scholarly journals Ultrasonographic estimation of Thyroid gland volume in healthy subjects of interior Sindh (Province of Pakistan).

2020 ◽  
Vol 27 (01) ◽  
pp. 185-190
Author(s):  
Jawad Ali Memon

Ultrasonography is the most common & easy method to estimate the thyroid gland volume. There is wide variation in the volume of the thyroid gland in normal individuals of different ages, sex, races & geography location. Objectives: To estimate the ultrasonographic thyroid gland volume & its reference range in healthy volunteers of interior Sindh, province of Pakistan. Study Design: Cross Sectional Prospective study. Setting: Conducted in Department of Radiology of PUMHS Nawabshah. Period: From 15 August 2017 to 15 February 2018. Material & Methods: Total 102 healthy subjects were included. The subjects having history of any thyroid disease or surgery, systematic disease, iodine deficiency or taking any drug were excluded. Every subject’s thyroid ultrasound was performed by experienced radiologist & thyroid gland volume of each lobe was calculated. Results: The mean total thyroid gland volume of all study subjects was 9.14+2.97 cm3. The mean volume of right lobe is significantly larger than that of left lobe (5.27+3.82 vs 3.82+1.41, p< 0.005). The mean thyroid volume of the male subjects was larger than in the females (11.67+3.06 vs 8.50+2.87 cm3), the difference between both sexes was statistically significant (p< 0.005) (Table-I). There was no statistically correlation was found between thyroid gland volume with body mass index ((p< 0.005). Conclusion: We tried to contribute to establish the reference values for our local population and further large studies are required to establish national wide reference values of thyroid gland volume.

2021 ◽  
Vol 8 (7) ◽  
pp. 864
Author(s):  
Chia D. Msuega ◽  
Aondoaseer A. Ugande ◽  
Kator P. Iorpagher ◽  
Ochekawo I. Obekpa ◽  
Abdullahi A. Abdullahi

Background: Thyroid gland volume is highly variable among communities. Current study was aimed to determine the local normative data on thyroid volume, assessed by ultrasonography in asymptomatic Nigerian adults.Methods: A prospective cross-sectional study conducted at a tertiary hospital between February 2020 to February 2021, which included 500 clinically asymptomatic adults in Makurdi, North-Central Nigeria. Age specific reference values for thyroid volume were obtained. Structured questionnaire was used to obtain information on other variables that could influence thyroid gland volume. The data obtained, including that from blood tests of thyroid function was collated and analysed using SPSS 23, with p=0.05.Results: The mean total thyroid gland volume for both lobes in the entire population of the study was 6.91±2.41 cm3. The mean thyroid volume for both lobes in males 7.09±2.60 cm3 was higher than that of females 6.73±2.38 cm3. The mean right and left lobe volumes were 3.56±1.14 cm3 and 3.35±1.10 cm3 respectively. The right lobe volume was significantly greater than the left lobe (p=0.000). There was a consistent steady increase in thyroid gland volume with increasing age for the general, male and female population until at least the 5th or 6th decade. The total thyroid gland volume significantly correlated with the individual’s body parameters. Highest correlation was found with height (r=0.256, p<0.05)).Conclusions: Ultrasonography was valuable in the determination of thyroid gland volume and normal values were different in various communities.


Author(s):  
A. J. Salaam ◽  
S. M. Danjem ◽  
A. A. Salaam ◽  
H. A. Angba ◽  
P. O. Ibinaiye

Objective: To sonographically determine the thyroid gland volume in normal adults in Jos University Teaching Hospital, as well as how it relates to anthropometric factors. Background: The thyroid gland is one of the largest endocrine glands in the body weighing about 10-25g.  It regulates the rate of metabolism and controls the growth and rate of function of many other systems in the body. These it does, by producing thyroid hormones, principally thyroxine (T4) and triiodothyronine (T3). The accurate estimation of the size of the thyroid is very important for the evaluation and management of thyroid disorders. Thus, knowing the normal size in a geographic location would form a baseline for detecting abnormalities. Ultrasonography is a cheap, readily available, easy to perform and non-invasive method to image the thyroid gland, hence its use in this resource-limited setting. Methods: This is a cross-sectional study of sonographic measurement of thyroid gland volume on 400 normal (healthy) adults in Jos, Plateau State, Northern part of Nigeria. All examinations were performed using LOGIC 5, a real-time ultrasound machine using a 10MHZ linear transducer and ultrasound transmission gel to act as a coupling gel. Measurements of each lobe and isthmus were obtained in longitudinal (length), transverse (width) and depth(breath) in centimetres (cm). Blood samples were taken for thyroid function tests. The weight and heights were obtained. The data obtained were statistically analyzed using SPSS software version 17. The results were presented in forms of tables, graphs and chart. Results: The mean thyroid volume for males   6.03 cm3±2.22 was higher than that of females 5.62 cm3±2.14. The mean right lobe volume (RLV) was 3.09 cm3±1.47 and that of males and females were 3.16 cm3 ±1.34 and 3.04 cm3 ±1.55 respectively. The mean left lobe volume (LLV) was 2.69 cm3 ± 1.37 and that of males and females were 2.89 cm3±1.32 and 2.57 cm3±1.39 respectively. The right lobe volume was significantly greater than the left lobe(p=0.000). The total mean isthmus volume was 0.27 cm3±0.31. The mean isthmus volume in males 0.3±0.28 is significantly higher than that of females 0.24±0.23 (p=0.025). The BMI increases in females with increasing age. BMI and BSA are higher in males. Conclusion: The volume obtained in this study was slightly lower than those reported by previous studies in Nigerian adults. The right lobe volume was higher than that of the left and the volume was higher in males compared to females. Anthropometric parameters were noted to affect the thyroid volume.


1986 ◽  
Vol 113 (2) ◽  
pp. 226-232 ◽  
Author(s):  
Laszlo Hegedüs ◽  
Dagmar Veiergang ◽  
Steen Karstrup ◽  
Jens Mølholm Hansen

Abstract. Thyroid function and thyroid gland volume, ultrasonically determined, were investigated in 27 hyperthyroid patients with solitary autonomous thyroid nodules before and during one year after 131I-treatment. Total thyroid volume decreased gradually from 40.9 ± 3.5 ml (mean ± sem) before treatment to 23.9 ± 1.8 ml (P < 0.001) at 3 months after 131I-treatment. No further change was observed. All but two patients received only one dose of 131I, and in spite of a significant decrease also of the non-adenoma side of the gland, none became hypothyroid. We conclude that 131I-therapy has an important place in the treatment of solitary autonomous thyroid nodules since all our patients became euthyroid within 3 months, only 2 of 27 patients needed more than one dose of 131I, no cases of hypothyroidism occurred, and thyroid volume was substantially decreased.


2018 ◽  
Vol 69 (4) ◽  
pp. 422-429
Author(s):  
Hedyeh Ziai ◽  
Nicole L. Lebo ◽  
Ania Z. Kielar ◽  
Michael J. Odell

Purpose To determine whether an ultrasonography (US)-defined thyroid volume can accurately predict substernal extension or tracheal narrowing. Methods After research ethics approval, we identified patients with thyroid nodules investigated with both US and computed tomography (CT). Reviewers assigned scores for both substernal extension and tracheal compression on CT using pre-established classification systems. Statistical analysis with receiver operating characteristic curve analysis was performed to find the US-determined thyroid volume thresholds that correlated with each substernal extension and tracheal compression. Results This study included 120 patients (mean age 63.4 years; SD ± 15.9; 67% female). Thirty-five patients (29%) had substernal extension. The mean US total thyroid gland volume in patients with and without substernal extension were 92.4 and 37.6 cm3, respectively ( P < .001). 86% of patients with substernal extension had tracheal narrowing vs. 27% of patients without substernal extension ( P < .0001). A cutoff dominant gland volume of ≥37.5 cm3 showed 83% sensitivity and 79% specificity for substernal extension (area under the curve [AUC] = 0.84). A total thyroid gland volume threshold of ≥37.8 cm3 showed 89% sensitivity and 87% specificity for any degree of tracheal narrowing (AUC = 0.90). Conclusions This study suggests that US volumes may be used as a predictor to identify those patients with thyroid enlargement who are most at risk of substernal extension and tracheal compression and who may benefit from preoperative CT imaging for optimal surgical and anesthetic planning.


1991 ◽  
Vol 124 (3) ◽  
pp. 238-244 ◽  
Author(s):  
Raija M. Takalo ◽  
Hanna P. Mäkäräinen ◽  
R. Kaarina Jaakkola

Abstract. The purpose of this work was to determine by ultrasound the volume and echo structure of the thyroid gland in 13-year-old schoolchildren in northern Finland. 76 healthy schoolchildren underwent cervical ultrasound examinations during the period of Jan-Feb 1990, performed with a real-time scanner using a 7.5 MHz linear transducer and direct contact method. The volume of each lobe was calculated according to the formula for a volume of rotation ellipsoid by multiplication of maximal thickness, width and height of the lobe by the correction factor 0.479. Any focal lesion that could be distinguished in the homogenous thyroid parenchyma was assessed for echogenicity as compared with the normal thyroid gland and was measured with electronic calipers. The mean thyroid volume was 6.5±1.6 ml (mean ±sd), being 6.3±1.8 ml in the boys and 6.7± 1.4 ml in the girls. The sex difference was not significant. The right lobe was significantly larger than the left one (mean 3.7 and 2.8 ml, respectively). Thyroid volume was correlated with body weight and body surface area in both sexes. Abnormal lesions in terms of echo structure were noted in one subject (1.3%). Comparing the results with the findings reported from other countries, it can be concluded that the thyroid volume in these 13-year-old Finnish schoolchildren was about 30% less than that reported for the same age group in the FRG (with insufficient iodine intake) and about 35% more than in 13-year-old schoolchildren in Sweden (with sufficient iodine intake).


2015 ◽  
Vol 143 (3-4) ◽  
pp. 141-145 ◽  
Author(s):  
Ertan Şahin ◽  
Umut Elboğa ◽  
Ebuzer Kalender

Introduction. It is important to know the size of the thyroid gland, and its normal value may vary among different geographic regions. Objective. In this study, we aimed to establish reference ranges for thyroid volume in euthyroid adults and to compare these results with the literature data. Methods. Between June 2011 and June 2012, 461 patients with normal laboratory results (serum TSH, anti-TG, anti-TPO antibodies and urine iodine level) that underwent thyroid gland ultrasound examination were retrospectively analyzed. Two hundred and 92 patients were females and 169 were males; the age range was 18-61 years with mean age 30.84?9.97 years. Length, breadth and thickness were measured, and the volume of each lobe was estimated using the ellipsoid formula. Results. The overall mean thyroid volume in all patients who were examined was 12.98?2.53 mL. The mean thyroid volume in females and males was 12.09?2.05 mL and 14.53?2.55, respectively (p<0.05). The right thyroid lobe volume was greater than the left in all patients of both sexes. In addition, the study establishes a significant correlation between the thyroid volume and height, weight and body surface area of the subjects of both sexes (p<0.05). In the light of our findings we can provide reference values in order to evaluate patients who have thyroid hyperplasia or who are considered as normal. Conclusion. We consider that further studies are necessary to establish national references thyroid volume for each country.


2000 ◽  
Vol 84 (2) ◽  
pp. 139-141 ◽  
Author(s):  
Michael Zimmermann ◽  
Pierre Adou ◽  
Toni Torresani ◽  
Christophe Zeder ◽  
Richard Hurrell

In areas where iodized salt is not available, oral iodized oil is often used to correct I deficiency despite a lack of consensus on the optimal dose or duration of effect, particularly in children, a main target group. Annual doses ranging from 400 to 1000 mg have been advocated for school-age children. Because lower doses of iodized oil have been shown to be effective in treating I deficiency in adults, the aim of this study was to evaluate the efficacy and safety of a low dose of oral iodized oil in goitrous I-deficient children. Goitrous children (n 104, mean age 8·4 years, range 6–12 years, 47 % female) received 0·4 ml oral iodized poppyseed-oil containing 200 mg I. Baseline measurements included I in spot urines (UI), serum thyroxine (T4), whole blood thyroid-stimulating hormone (TSH), and thyroid-gland volume using ultrasound. At 1, 5, 10, 15, 30 and 50 weeks post-intervention, UI, TSH and T4 were measured. At 10, 15, 30 and 50 weeks, thyroid-gland volume was remeasured. At 30 and 50 weeks the mean percentage change in thyroid volume from baseline was -35 % and -41 % respectively. The goitre rate fell to 38 % at 30 weeks and 17 % at 50 weeks. No child showed signs of I-induced hypo- or hyperthyroidism. UI remained significantly increased above baseline for the entire year (P < 0·001); the median UI at 50 weeks was 97 μg/l, at the World Health Organization cut-off value (100 μg/l) for I-deficiency disorders risk. In this group of goitrous children, an oral dose of 200 mg I as Lipiodol (Guerbert, Roissy CdG Cedex, France) was safe and effective for treating goitre and maintaining normal I status for at least 1 year.


2011 ◽  
Vol 2011 ◽  
pp. 1-4 ◽  
Author(s):  
Mohamed Yousef ◽  
Abdelmoneim Sulieman ◽  
Bushra Ahmed ◽  
Alsafi Abdella ◽  
Khaled Eltom

This study aimed to establish a local reference of thyroid volume in Sudanese normal subjects using ultrasound. A total of 103 healthy subjects were studied, 28 (27.18%) females and 75 (72.82%) males. Thyroid volume was estimated usingellipsoid formula. The mean age and range of the subjects was 21.8 (19–29) years; the mean body mass index (BMI) was 22.3 (16.46–26.07) kg/m2. The overall mean volume ± SD volume of the thyroid gland for both lobes in all the patients studied was 6.44 ± 2.44 mL. The mean volume for both lobes in females and males were 5.78 ± 1.96 mL and 6.69 ± 2.56 mL, respectively. The males' thyroid volume was greater than the females'. The mean volume of the right and left lobes of the thyroid gland in males and females were 3.38 ± 1.37 mL and 3.09 ± 1.24 mL, respectively. The right thyroid lobe volume was greater than the left. The values obtained in this study were lower than those reported from previous studies.


Author(s):  
Sibel Bayramoglu ◽  
Sema Aksoy ◽  
Akgun Unat ◽  
Fatma Beyazal Celiker ◽  
Seyma Yıldız ◽  
...  

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