Effects of an exercise programme with people living with HIV: research in a disadvantaged setting

ObjectiveTo explore experiences participating in a group-based physiotherapist (PT)-led exercise programme among people living with HIV and complex multimorbidity.DesignWe conducted a qualitative descriptive study using semistructured interviews.Recruitment and settingWe recruited community-dwelling adults living with HIV who engaged in a group-based PT-led exercise programme within an HIV-specialty hospital in Toronto, Canada. Interviews were conducted in-person or by telephone.ParticipantsEight men and two women with a median age of 58 years and median of six concurrent conditions in addition to HIV, who had attended ≥2 classes of the exercise programme.Data collectionInterviews explored (1) reasons for engaging in the programme, (2) experiences with exercise prior to and after joining the programme, (3) facilitators and barriers to engagement and (4) perceived impacts of participation on health and disability. We administered the HIV Disability Questionnaire and a demographic questionnaire.ResultsExperiences spanned perspectives prior to, during and after the PT-led exercise programme. Reasons for engaging in the programme included addressing health-related goals. Participants identified accessibility, the flexible schedule, interprofessional staff and the HIV-specific, group-based environment as facilitators to engagement. Participants reported high attendance rates, but identified episodic health challenges and overcrowded space as potential barriers to attending exercise classes. Perceived impacts on health and disability outcomes included improved physical, mental, social and cognitive health, and activities of daily living. Anticipated or actual experiences transitioning to independent exercise included facilitators (supportive programme leaders) and barriers (challenges motivatiing self to exercise alone).ConclusionsFeatures of the programme that facilitated engagement included the interprofessional, group-based environment that offered tailored exercise in an HIV-specific facility, whereby participants perceived benefits in domains of health and disability. However, challenges transitioning to independent exercise remain. Group-based PT-led exercise programmes may facilitate engagement in exercise among adults living with HIV and complex multimorbidity.

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The effects of a 16-week aerobic exercise programme on cognitive function in people living with HIV

AIDS Care ◽

10.1080/09540121.2016.1263723 ◽

2016 ◽

Vol 29 (6) ◽

pp. 667-674 ◽

Cited By ~ 17

Author(s):

Adam McDermott ◽

Lilia Zaporojan ◽

Patricia McNamara ◽

Colin P. Doherty ◽

Janice Redmond ◽

...

Keyword(s):

Cognitive Function ◽

Aerobic Exercise ◽

Exercise Programme ◽

People Living With Hiv ◽

Living With Hiv

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Creation of Data Repositories to Advance Nursing Science

Western Journal of Nursing Research ◽

10.1177/0193945917749481 ◽

2017 ◽

Vol 41 (1) ◽

pp. 78-95 ◽

Cited By ~ 2

Author(s):

Joseph Perazzo ◽

Margaret Rodriguez ◽

Jackson Currie ◽

Robert Salata ◽

Allison R. Webel

Keyword(s):

Collaborative Research ◽

Data Repository ◽

People Living With Hiv ◽

Cross Sectional ◽

Data Repositories ◽

Nursing Science ◽

Hiv Research ◽

Systematic Planning ◽

Living With Hiv ◽

And Training

Data repositories are a strategy in line with precision medicine and big data initiatives, and are an efficient way to maximize data utility and form collaborative research relationships. Nurse researchers are uniquely positioned to make a valuable contribution using this strategy. The purpose of this article is to present a review of the benefits and challenges associated with developing data repositories, and to describe the process we used to develop and maintain a data repository in HIV research. Systematic planning, data collection, synthesis, and data sharing have enabled us to conduct robust cross-sectional and longitudinal analyses with more than 200 people living with HIV. Our repository building has also led to collaboration and training, both in and out of our organization. We present a pragmatic and affordable way that nurse scientists can build and maintain a data repository, helping us continue to make to our understanding of health phenomena.

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Bartlett's Medical Management of HIV Infection

10.1093/med/9780190924775.001.0001 ◽

2019 ◽

Author(s):

John G. Bartlett ◽

Robert R. Redfield ◽

Paul A. Pham

Keyword(s):

Hiv Infection ◽

Nurse Practitioners ◽

Medical Management ◽

Clinical Care ◽

Hiv Infections ◽

Physician Assistants ◽

People Living With Hiv ◽

Hiv Research ◽

Reference Format ◽

Living With Hiv

With more than 30 million people living with HIV, nearly 2 million new HIV infections, and 1 million deaths in 2017 globally, the HIV epidemic continues to exert a considerable deleterious impact on the health of individuals, communities, and the economic growth of nations. However, remarkable advances have also been achieved: improvements in our scientific understanding of the biology of HIV, how it causes disease, and its prevention and treatment, coupled with unprecedented multi-sectoral global efforts, have resulted in rendering HIV infection essentially a manageable chronic disease. The 17th edition of Bartlett’s Medical Management of HIV Infection offers the best-available clinical guidance for treatment of patients with HIV, all in a portable, quick-reference format. Edited by preeminent and pioneering authorities in HIV research and clinical care, it has earned its status as the definitive work for physicians, physician assistants, nurse practitioners, pharmacists, and anyone working in the care of persons with HIV.

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The effects of a 12-week exercise programme for people living with HIV in Ethiopia

Sport Sciences for Health ◽

10.1007/s11332-021-00801-3 ◽

2021 ◽

Author(s):

Bizuneh Yirga Gebermariam ◽

Rowena Naidoo ◽

Verusia Chetty

Keyword(s):

Exercise Programme ◽

People Living With Hiv ◽

Living With Hiv

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Effects of a four-week aerobic exercise programme on depression, anxiety and general self-efficacy in people living with HIV on highly active anti-retroviral therapy

AIDS Care ◽

10.1080/09540121.2021.1883513 ◽

2021 ◽

pp. 1-9

Author(s):

Nse A. Odunaiya ◽

Samuel A. Agbaje ◽

Opeyemi Mercy Adegoke ◽

Oluwafemi O. Oguntibeju

Keyword(s):

Aerobic Exercise ◽

Self Efficacy ◽

Exercise Programme ◽

People Living With Hiv ◽

Highly Active ◽

Living With Hiv ◽

General Self Efficacy

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Evaluating the Impact of Incentives on Clinical Trial Participation: Protocol for a Mixed-Methods, Community-Engaged Study (Preprint)

10.2196/preprints.33608 ◽

2021 ◽

Author(s):

Jerome Timothy Galea ◽

Karah Yeona Greene ◽

Brandon Nguyen ◽

Andrea N. Polonijo ◽

Karine Dubé ◽

...

Keyword(s):

Clinical Trial ◽

Nationwide Survey ◽

Trial Participation ◽

People Living With Hiv ◽

Monetary Incentives ◽

Relative Importance ◽

Clinical Trial Participation ◽

Hiv Research ◽

Living With Hiv ◽

Research Studies

BACKGROUND Monetary incentives in research are frequently used to support participant recruitment and retention. However, scant empirical data exist regarding how researchers decide upon the type and amount of incentives offered. Likewise, there is little guidance to assist study investigators and institutional review boards (IRBs) in their decision-making on incentives. Monetary incentives, in addition to other factors such as the risk of harm or other intangible benefits, guide individuals’ decisions to enroll in research studies. These factors emphasize the need for evidence-informed guidance for study investigators and IRBs when determining the type and amount of incentives to provide to research participants. OBJECTIVE The specific aims are to: Aim 1) characterize key stakeholders’ views on and assessment of incentives in biomedical HIV research; Aim 2) reach consensus among stakeholders on the factors considered when choosing research incentives, including their relative importance, and, Aim 3) pilot test the use of the guidance from Aims 1 and 2 by presenting stakeholders vignettes of hypothetical research studies for which they will choose corresponding incentive types. METHODS Our two-year study involves monthly, active engagement with a stakeholder advisory board (SAB) of people living with HIV, researchers, and IRB members. For Aim 1, we will conduct a nationwide survey (N=300) among people living with HIV to understand their views regarding incentives used in HIV research. In Aim 2, we will collect qualitative data using focus groups with people living with HIV (n=60) and key informant interviews with stakeholders involved in HIV research (people living with HIV, IRB members, biomedical HIV researchers; n=36), to extend and deepen our understanding of how incentives in HIV research are perceived. These participants will also complete a conjoint analysis experiment to understand the relative importance that key attributes of HIV research studies have on study participation. Data from the nationwide survey (Aim 1) will be triangulated with the qualitative and conjoint analysis data (Aim 2) to create 25 “vignettes” that describe hypothetical HIV research studies. Finally, (Aim 3) individuals from each stakeholder group will select the most appropriate incentive they feel should be used in each of the 25 vignettes. RESULTS The SAB began monthly meetings in March 2021. All study aims are expected to be completed by December 2022. CONCLUSIONS By studying the role of incentives in HIV clinical trial participation, we will establish a decision-making paradigm to guide the choice of incentives for HIV –and eventually other types of similar research –to facilitate ethical recruitment of clinical research participants. CLINICALTRIAL ClinicalTrials.gov NCT04809636; https://clinicaltrials.gov/ct2/show/NCT04809636

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Design, analysis, and reporting of pilot studies in HIV: a systematic review and methodological study

Pilot and Feasibility Studies ◽

10.1186/s40814-021-00934-9 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Hussein Ali El-Khechen ◽

Mohammed Inam Ullah Khan ◽

Selvin Leenus ◽

Oluwatobi Olaiya ◽

Zoha Durrani ◽

...

Keyword(s):

Qualitative Methods ◽

Sample Size ◽

Contextual Information ◽

Primary Objective ◽

People Living With Hiv ◽

Size Estimation ◽

Methodological Study ◽

Pilot Studies ◽

Hiv Research ◽

Living With Hiv

Abstract Background Pilot studies are essential in determining if a larger study is feasible. This is especially true when targeting populations that experience stigma and may be difficult to include in research, such as people with HIV. We sought to describe how pilot studies have been used to inform HIV clinical trials. Methods We conducted a methodological study of pilot studies of interventions in people living with HIV published until November 25, 2020, using Medline, Embase, and Cochrane Controlled Register of Trials (CENTRAL). We extracted data on their nomenclature, primary objective, use of progression criteria, sample size, use of qualitative methods, and other contextual information (region, income, level, type of intervention, study design). Results Our search retrieved 10,597 studies, of which 248 were eligible. The number of pilot studies increased steadily over time. We found that 179 studies (72.2%) used the terms “pilot” or “feasibility” in their title, 65.3% tested feasibility as a primary objective, only 2% used progression criteria, 23.9% provided a sample size estimation and only 30.2% used qualitative methods. Conclusions Pilot studies are increasingly being used to inform HIV research. However, the titles and objectives are not always consistent with piloting. The design and reporting of pilot studies in HIV could be improved.

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Current Interventions for People Living with HIV Who Use Alcohol: Why Gender Matters

Current HIV/AIDS Reports ◽

10.1007/s11904-021-00558-x ◽

2021 ◽

Author(s):

Wendee M. Wechsberg ◽

Felicia A. Browne ◽

Courtney Peasant Bonner ◽

Yukiko Washio ◽

Brittni N. Howard ◽

...

Keyword(s):

Viral Suppression ◽

Intervention Studies ◽

Alcohol Misuse ◽

Small Samples ◽

People Living With Hiv ◽

Alcohol Intervention ◽

The World ◽

Significant Efficacy ◽

Hiv Research ◽

Living With Hiv

Abstract Purpose of Review Alcohol is the most misused substance in the world. For people living with HIV (PLWH), alcohol misuse may impact ART adherence and viral suppression. This review of the most recently published alcohol intervention studies with PLWH examines how these studies considered gender in the samples, design, and analyses. Recent Findings Three searches were conducted initially, and 13 intervention studies fit our criteria with alcohol outcomes. In general, most studies did not consider gender and had used small samples, and few demonstrated significant efficacy/effectiveness outcomes. Five studies considered gender in their samples or analyses and/or were woman-focused with larger samples and demonstrated significant outcomes. Summary It is essential for women who misuse alcohol to not only be well represented in alcohol and HIV research but also for studies to consider the barriers to reaching them and their contextual demands and/or co-occurring issues that may affect participation and outcomes in intervention research.

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Ageism in HIV Research

Innovation in Aging ◽

10.1093/geroni/igaa057.3106 ◽

2020 ◽

Vol 4 (Supplement_1) ◽

pp. 847-847

Author(s):

Tonya Taylor

Keyword(s):

Older Adults ◽

Sexual Behaviors ◽

Successful Aging ◽

People Living With Hiv ◽

Sexual Intimacy ◽

Media Campaigns ◽

Sex And Sexuality ◽

Hiv Research ◽

The Life Course ◽

Living With Hiv

Abstract Sex and sexuality are important determinants of health and wellbeing across the life course. The desire and capacity for sexual intimacy and pleasure among older adults are neglected areas of research due to ageist assumptions that they no longer engage in sexual activity. These assumptions are most pronounced in HIV research, where we aggressively studied intimate details of sexual behaviors of people living with HIV until they became “old.” Interest in the sexual behaviors among older adults with HIV has waned in HIV prevention, suggesting an inherent ageism within the field. We will discuss emerging new HIV and STI risks for older adults, declining trends in gerosexuality funding, HIV media campaigns targeted for older adults, and new evidence that suggest that interventions that engage older adults with HIV in conversations about sexual health, menopause, and erectile dysfunction may be an effective strategy for promoting overall successful aging

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