scholarly journals Natural products targeting the p53 tumor suppressor-A novel approach for future cancer therapy- A review

2021 ◽  
Vol 1 (2) ◽  
pp. 167-176
Author(s):  
Ali Esmail Al-Snafi
Keyword(s):  
Natural Products ◽  
Cancer Therapy ◽  
Tumor Suppressor ◽  
Medicinal Plants ◽  
Cancer Prevention ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
Novel Approach ◽  
Prevention And Treatment ◽  
Expression And Activity

Mutations of p53, a tumor suppressor gene, are known to be involved in multiplication and metastasis of tumors. A number of natural products targeted the p53-MDM2 pathway. This review is an attempt to highlight the medicinal plants that can modulate the expression and activity ofp53tumor suppression, for cancer prevention and treatment.

A synergistic polyphosphoester-based co-delivery system of the anticancer drug doxorubicin and the tumor suppressor gene p53 for lung cancer therapy

2018 ◽  
Vol 6 (20) ◽  
pp. 3262-3273 ◽  
Author(s):  
Jie Liu ◽  
Jinlin He ◽  
Mingzu Zhang ◽  
Guoqiang Xu ◽  
Peihong Ni
Keyword(s):  
Lung Cancer ◽  
Cancer Therapy ◽  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Anticancer Drug ◽  
Delivery System ◽  
Suppressor Gene ◽  
Polymeric Prodrug ◽  
Lung Cancer Therapy ◽  
Tumor Suppressor Gene P53

Hybrid micelles composed of polymeric prodrug and gene carrier were constructed by polyphosphoester-based co-delivery system for lung cancer therapy.

Sequentially Site‐Specific Delivery of Apoptotic Protein and Tumor‐Suppressor Gene for Combination Cancer Therapy

Small ◽  
2019 ◽  
Vol 15 (40) ◽  
pp. 1902998 ◽  
Author(s):  
Xiaojie Chen ◽  
Qiuwen Zhu ◽  
Xiao Xu ◽  
Shiyang Shen ◽  
Ying Zhang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Tumor Suppressor ◽  
Tumor Suppressor Gene ◽  
Suppressor Gene ◽  
Site Specific ◽  
Apoptotic Protein ◽  
Combination Cancer Therapy
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