scholarly journals The anxiolytic effect of some plant extracts in clinical trials and animal models

2021 ◽  
Vol 5 (3) ◽  
pp. 038-043
Author(s):  
Malkhaz Makashvili ◽  
Giorgi Andronikashvili ◽  
Tamila Bagashvili ◽  
Tea Gurashvili ◽  
Ketevan Gogeshvili ◽  
...  
Keyword(s):  
Animal Models ◽  
Prescription Drugs ◽  
Plant Extracts ◽  
Anxiolytic Effect ◽  
Endemic Plant ◽  
Strong Argument ◽  
Current Drug ◽  
Animal Models Of Anxiety ◽  
Experimental Trials ◽  
Endemic Plant Species

The phenomenon of anxiety remains poorly understood and there is much to be learnt about its’s effective treatment. Here we discuss the data of available scientific literature concerning the use of plant derived extracts in the treatment of anxiety. Study of the treating effects of natural alternatives to prescription drugs is very important in regard to limitations of current drug therapies. Significance of the study of treating efficacy of endemic plant species, endemic to Georgia in particular, and the use of animal models, such as rat grooming and rat behavior in maze, for evaluation of the anxiolytic efficacy of phytomedicines is discussed as well. We conclude, that medical as well as experimental trials in animal models of anxiety provide strong argument for the use of plant extracts as an alternative to the current drug therapies for anxiety.

Anxiolytic-like profiles of histamine H3 receptor agonists in animal models of anxiety: a comparative study with antidepressants and benzodiazepine anxiolytic

2009 ◽  
Vol 205 (2) ◽  
pp. 177-187 ◽  
Author(s):  
Fumikazu Yokoyama ◽  
Miki Yamauchi ◽  
Masayo Oyama ◽  
Kunihiro Okuma ◽  
Kaname Onozawa ◽  
...  
Keyword(s):  
Animal Models ◽  
Comparative Study ◽  
Histamine H3 Receptor ◽  
Receptor Agonists ◽  
H3 Receptor ◽  
Animal Models Of Anxiety ◽  
Histamine H3

scholarly journals Mauritian coloured nectar no longer a mystery: a visual signal for lizard pollinators

2006 ◽  
Vol 2 (2) ◽  
pp. 165-168 ◽  
Author(s):  
Dennis M Hansen ◽  
Karin Beer ◽  
Christine B Müller
Keyword(s):  
Experimental Evidence ◽  
Plant Species ◽  
Flowering Plants ◽  
Visual Signal ◽  
Honest Signal ◽  
Endemic Plant ◽  
Floral Trait ◽  
Flower Visitation ◽  
Artificial Flowers ◽  
Endemic Plant Species

Most floral nectars are clear as water, and the enigmatic coloured nectar in three endemic plant species in Mauritius has puzzled scientists studying it. One hypothesis about the possible ecological function of coloured nectar is that it serves as a visual signal for pollinators. Recent studies have shown that at least two of the three Mauritian plant species with coloured nectar are visited and pollinated by endemic Phelsuma geckos. We here provide experimental evidence for the visual signal hypothesis by showing that Phelsuma ornata geckos prefer coloured over clear nectar in artificial flowers. In flowering plants, coloured nectar could additionally function as an honest signal that allows pollinators to assert the presence and judge the size of a reward prior to flower visitation, and to adjust their behaviour accordingly, leading to increased pollinator efficiency. Our study provides a first step in understanding this rare and intriguing floral trait.

scholarly journals Pyrrolizidine Alkaloids and Fatty Acids from the Endemic Plant Species Rindera umbellata and the Effect of Lindelofine-N-oxide on Tubulin Polymerization

Molecules ◽  
2013 ◽  
Vol 18 (9) ◽  
pp. 10694-10706 ◽  
Author(s):  
Boris Mandić ◽  
Milena Simić ◽  
Ivan Vučković ◽  
Ljubodrag Vujisić ◽  
Miroslav Novaković ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Plant Species ◽  
Pyrrolizidine Alkaloids ◽  
Tubulin Polymerization ◽  
Endemic Plant ◽  
Endemic Plant Species

Investigation of the synergistic effects of paclitaxel and herbal substances and endemic plant extracts on cell cycle and apoptosis signal pathways in prostate cancer cell lines

Gene ◽  
2019 ◽  
Vol 687 ◽  
pp. 261-271 ◽  
Author(s):  
Zeynep Özlem Doğan Şiğva ◽  
Tuğçe Balci Okcanoğlu ◽  
Çığır Biray Avci ◽  
Sunde Yilmaz Süslüer ◽  
Çağla Kayabaşi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cell Cycle ◽  
Cell Lines ◽  
Cancer Cell ◽  
Plant Extracts ◽  
Prostate Cancer Cell ◽  
Synergistic Effects ◽  
Signal Pathways ◽  
Endemic Plant ◽  
Prostate Cancer Cell Lines

Genetic Animal Models of Anxiety

2009 ◽  
pp. 179-189
Author(s):  
Rupert J. Egan ◽  
Carisa L. Bergner ◽  
Peter C. Hart ◽  
Justin L. LaPorte ◽  
Allan V. Kalueff
Keyword(s):  
Animal Models ◽  
Animal Models Of Anxiety
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