Assessment of protective effects of glucosamine and N-acetyl glucosamine against DNA damage induced by hydrogen peroxide in human lymphocytes

2014 ◽  
Vol 37 (4) ◽  
pp. 427-432 ◽  
Author(s):  
Khadijeh Jamialahmadi ◽  
Fatemeh Soltani ◽  
Maryam Nabavi fard ◽  
Javad Behravan ◽  
Fatemeh Mosaffa
Keyword(s):  
Hydrogen Peroxide ◽  
Dna Damage ◽  
Human Lymphocytes ◽  
Protective Effects

scholarly journals Protective effects of black tea extract against oxidative DNA damage in human lymphocytes

2015 ◽  
Vol 13 (2) ◽  
pp. 1839-1844 ◽  
Author(s):  
MIRIAM JEŽOVIČOVÁ ◽  
KATARÍNA KOŇARIKOVÁ ◽  
ZDEŇKA ĎURAČKOVÁ ◽  
JÁN KERESTEŠ ◽  
GABRIEL KRÁLIK ◽  
...  
Keyword(s):  
Dna Damage ◽  
Oxidative Dna Damage ◽  
Human Lymphocytes ◽  
Black Tea ◽  
Protective Effects ◽  
Black Tea Extract ◽  
Tea Extract

Effects of Chlorophyll-Related Compounds on Hydrogen Peroxide Induced DNA Damage within Human Lymphocytes

2005 ◽  
Vol 53 (7) ◽  
pp. 2746-2750 ◽  
Author(s):  
Ching-Yun Hsu ◽  
Chi-Ming Yang ◽  
Chiao-Ming Chen ◽  
Pi-Yu Chao ◽  
Shene-Pin Hu
Keyword(s):  
Hydrogen Peroxide ◽  
Dna Damage ◽  
Human Lymphocytes ◽  
Related Compounds

Protective effects of β-glucan extracted from Agaricus brasiliensis against chemically induced DNA damage in human lymphocytes

2006 ◽  
Vol 22 (4) ◽  
pp. 285-291 ◽  
Author(s):  
J. P. F Angeli ◽  
L. R. Ribeiro ◽  
M. L. C. Gonzaga ◽  
S. de A. Soares ◽  
M. P. S. N. Ricardo ◽  
...  
Keyword(s):  
Dna Damage ◽  
Human Lymphocytes ◽  
Protective Effects ◽  
Agaricus Brasiliensis ◽  
Chemically Induced

scholarly journals Protective effects of olive oil phenolics oleuropein and hydroxytyrosol against hydrogen peroxide-induced DNA damage in human peripheral lymphocytes

2021 ◽  
Vol 71 (1) ◽  
pp. 131-141
Author(s):  
Nataša Zorić ◽  
Nevenka Kopjar ◽  
Jadranka Vuković Rodriguez ◽  
Siniša Tomić ◽  
Ivan Kosalec
Keyword(s):  
Dna Damage ◽  
Free Radical ◽  
Antioxidant Capacity ◽  
Olive Oil ◽  
Human Lymphocytes ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Protective Effects ◽  
Human Peripheral Lymphocytes ◽  
Primary Dna Damage

AbstractThis study investigates antioxidant capacity and protective effects of phenolic compounds oleuropein (OLP) and hydroxytyrosol (HT), present in olive oil and olive leaves, against H2O2-induced DNA damage in human peripheral lymphocytes. Antioxidant potency was determined using the measurement of radical-scavenging activity (ABTS∙+ assay), ferric reducing power (FRAP assay) and cupric reducing antioxidant capacity (CUPRAC assay). Both substances were found to be potent antioxidant agents due to their free radical-scavenging activities. Antigenotoxic effects of oleuropein and hydroxytyrosol against H2O2-induced damage in human lymphocytes were evaluated in vitro by alkaline comet assay. At tested concentrations (1, 5, 10 µmol L−1), oleuropein and hydroxytyrosol did not induce a significant increase of primary DNA damage in comparison with the negative control. Pretreatment of human lymphocytes with each of the substances for 120 min produced a dose-dependent reduction of primary DNA damage in the tested cell type. Hydroxytyrosol showed a better protective effect against H2O2-induced DNA breaks than oleuropein which could be associated with their free radical-scavenging efficacy.

scholarly journals Antioxidant activity of herbaceous plant extracts protect against hydrogen peroxide-induced DNA damage in human lymphocytes

2013 ◽  
Vol 6 (1) ◽  
pp. 490 ◽  
Author(s):  
Kuan-Hung Lin ◽  
Yan-Yin Yang ◽  
Chi-Ming Yang ◽  
Meng-Yuan Huang ◽  
Hsiao-Feng Lo ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Dna Damage ◽  
Antioxidant Activity ◽  
Plant Extracts ◽  
Human Lymphocytes ◽  
Herbaceous Plant
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