Enhancement of Clearances by Activated Charcoal in an in Vitro Model of Peritoneal Dialysis

1982 ◽  
Vol 6 (2-3) ◽  
pp. 85-95 ◽  
Author(s):  
Howard L. Lang ◽  
Karl D. Nolph ◽  
Terry J. McGary
Keyword(s):  
Peritoneal Dialysis ◽  
Activated Charcoal ◽  
In Vitro Model ◽  
Vitro Model

scholarly journals In Vitro Evaluation of the Activities of Telavancin, Cefazolin, and Vancomycin against Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus in Peritoneal Dialysate

2007 ◽  
Vol 51 (12) ◽  
pp. 4521-4524 ◽  
Author(s):  
Frances L. Clouse ◽  
Laurie B. Hovde ◽  
John C. Rotschafer
Keyword(s):  
Staphylococcus Aureus ◽  
Peritoneal Dialysis ◽  
In Vitro Model ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Dialysis Fluid ◽  
Methicillin Resistant ◽  
Peritoneal Dialysate ◽  
Peritoneal Dialysis Fluid ◽  
Vitro Model

ABSTRACT This study compared the ability of telavancin to the ability of cefazolin and vancomycin to eliminate staphylococci from peritoneal dialysis fluid by using a static in vitro model to simulate the conditions of peritoneal dialysis. The results showed that telavancin exhibited statistically significantly better kill (P < 0.05) against both methicillin-susceptible and methicillin-resistant Staphylococcus aureus.

AN ANALYSIS OF CONTINUOUS FLOW PERITONEAL DIALYSIS (CFPD) KINETICS USING AN IN-VITRO MODEL

ASAIO Journal ◽  
2002 ◽  
Vol 48 (2) ◽  
pp. 177
Author(s):  
M. Roberts ◽  
E. Dinovo ◽  
N. Yanagawa ◽  
D. B.N. Lee
Keyword(s):  
Peritoneal Dialysis ◽  
Continuous Flow ◽  
In Vitro Model ◽  
Vitro Model

Biocompatibility Assessment of Peritoneal Dialysis Solutions With a New In Vitro Model of Preconditioned Human HL60 Cells

2009 ◽  
Vol 33 (7) ◽  
pp. 544-550 ◽  
Author(s):  
Sebastian Koball ◽  
Gero Korten ◽  
Jan Stange ◽  
Reinhard Schmidt ◽  
Steffen Mitzner
Keyword(s):  
Peritoneal Dialysis ◽  
In Vitro Model ◽  
Hl60 Cells ◽  
Vitro Model ◽  
Dialysis Solutions ◽  
Peritoneal Dialysis Solutions

Continuous Ambulatory Peritoneal Dialysis (CAPD) Peritonitis: The Effect of Antibiotic on the Adherence of Coagulase-Negative Staphylococci to Silicone Rubber Catheter Material

1989 ◽  
Vol 9 (2) ◽  
pp. 103-105 ◽  
Author(s):  
Roger G. Finch ◽  
Richard Edwards ◽  
Rachel Filik ◽  
Mark H. Wilcox
Keyword(s):  
Peritoneal Dialysis ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
Silicone Rubber ◽  
In Vitro Model ◽  
Major Complication ◽  
Drug Selection ◽  
Coagulase Negative Staphylococci ◽  
Vitro Model ◽  
Rubber Catheter

Peritonitis is the major complication of continuous ambulatory peritoneal dialysis (CAPO) and is caused predominantly by coagulase-negative staphylococci (CNS). Adherence to the silicone rubber Tenckhoff catheter has been identified as one factor in the pathogenesis and persistence of these infections. We have studied the adherence of CNS from patients and controls to silicone rubber in an in vitro model to determine whether this phenomenon can be modified by antibiotics. Adherence was strong for 7/27 (26%) CAPO isolates and for 3/27 (11%) of control strains. The strongly adherent CAPO isolates, when exposed to subinhibitory concentrations of vancomycin, cefuroxime, and ciprofloxacin, showed minimal alteration in adherence with vancomycin in both broth and used dialysate, whereas cefuroxime and ciprofloxacin both significantly reduced it. These observations may have implications for drug selection and prevention of CAPO peritonitis caused by CNS.

scholarly journals 1160 AN IN VITRO MODEL FOR ASSESSING ANTIMICROBIAL ACTIVITY DURING PERITONEAL DIALYSIS

1985 ◽  
Vol 19 (4) ◽  
pp. 304A-304A
Author(s):  
Itamar Shalit ◽  
David F Welch ◽  
Melvin I Marks
Keyword(s):  
Antimicrobial Activity ◽  
Peritoneal Dialysis ◽  
In Vitro Model ◽  
Vitro Model

An in vitro model for investigation of vitamin A effects on wound healing

2021 ◽  
pp. 1-6
Author(s):  
Hoda Keshmiri Neghab ◽  
Mohammad Hasan Soheilifar ◽  
Gholamreza Esmaeeli Djavid
Keyword(s):  
Wound Healing ◽  
Endothelial Cell ◽  
Vitamin A ◽  
In Vitro Model ◽  
Cellular Proliferation ◽  
Endothelial Cell Migration ◽  
Normal Fibroblast ◽  
Anti Inflammatory ◽  
Vitro Model

Abstract. Wound healing consists of a series of highly orderly overlapping processes characterized by hemostasis, inflammation, proliferation, and remodeling. Prolongation or interruption in each phase can lead to delayed wound healing or a non-healing chronic wound. Vitamin A is a crucial nutrient that is most beneficial for the health of the skin. The present study was undertaken to determine the effect of vitamin A on regeneration, angiogenesis, and inflammation characteristics in an in vitro model system during wound healing. For this purpose, mouse skin normal fibroblast (L929), human umbilical vein endothelial cell (HUVEC), and monocyte/macrophage-like cell line (RAW 264.7) were considered to evaluate proliferation, angiogenesis, and anti-inflammatory responses, respectively. Vitamin A (0.1–5 μM) increased cellular proliferation of L929 and HUVEC (p < 0.05). Similarly, it stimulated angiogenesis by promoting endothelial cell migration up to approximately 4 fold and interestingly tube formation up to 8.5 fold (p < 0.01). Furthermore, vitamin A treatment was shown to decrease the level of nitric oxide production in a dose-dependent effect (p < 0.05), exhibiting the anti-inflammatory property of vitamin A in accelerating wound healing. These results may reveal the therapeutic potential of vitamin A in diabetic wound healing by stimulating regeneration, angiogenesis, and anti-inflammation responses.

Sign in / Sign up

Export Citation Format

Share Document