Elevated mean platelet volume is associated with gestational diabetes mellitus

2014 ◽  
Vol 30 (9) ◽  
pp. 640-643 ◽  
Author(s):  
Ozlem Turhan Iyidir ◽  
Ceyla Konca Degertekin ◽  
Banu Aktas Yilmaz ◽  
Fusun Balos Toruner ◽  
Mujde Akturk ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Mean Platelet Volume ◽  
Platelet Volume

scholarly journals Mean Platelet Volume and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Zhongwei Zhou ◽  
Hongmei Chen ◽  
Mingzhong Sun ◽  
Huixiang Ju
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Mean Platelet Volume ◽  
Meta Analysis ◽  
Random Effect ◽  
Random Effect Model ◽  
Cochrane Library ◽  
Platelet Volume

Aim. To evaluate the association between mean platelet volume (MPV) and gestational diabetes mellitus (GDM). Methods. A systematic literature search was performed in PubMed, EMBASE, Web of Science, and The Cochrane Library up to 4 September 2017. Pooled standardized mean differences (SMD) and 95% confidence interval (CI) were calculated using a random-effect model. Results. Nineteen studies comprising 1361 GDM patients and 1911 normal pregnant women were included. MPV was increased in GDM patients when compared with healthy pregnant women (SMD: 0.79; 95% CI: 0.43–1.16; P<0.001). Subgroup analyses revealed that such trend was consistent in the third-trimester (SMD: 1.35; 95% CI: 0.72–1.98), Turkish (SMD: 0.81; 95% CI: 0.43–1.19), and Italian (SMD: 2.78; 95% CI: 2.22–3.34) patients with GDM and the patients diagnosed based on Carpenter and Coustan criteria (SMD: 1.04; 95% CI: 0.42–1.65). Significantly higher MPV also were observed within cross-sectional studies (SMD: 0.99; 95% CI: 0.49–1.49). Remarkable between-study heterogeneity and potential publication bias were observed in this meta-analysis; however, sensitivity analysis indicated that the results were not unduly influenced by any single study. Conclusions. GDM patients are accompanied by increased MPV, strengthening the clinical evidence that MPV may be a predictive marker for GDM.

Could mean platelet volume be a predictive marker for gestational diabetes mellitus?

Hematology ◽  
2008 ◽  
Vol 13 (1) ◽  
pp. 46-48 ◽  
Author(s):  
Alev Akyol Erikçi ◽  
Murat Muhçu ◽  
Özgür Dündar ◽  
Ahmet Öztürk
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Mean Platelet Volume ◽  
Predictive Marker ◽  
Platelet Volume

scholarly journals Relationship between mean platelet volume and vitamin D deficiency in gestational diabetes mellitus

2015 ◽  
Vol 59 (5) ◽  
pp. 448-454 ◽  
Author(s):  
Esra Bahar Gur ◽  
Muammer Karadeniz ◽  
Mine Genc ◽  
Fatma Eskicioglu ◽  
Murat Yalcin ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Vitamin D ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Vitamin D Deficiency ◽  
Mean Platelet Volume ◽  
Platelet Volume

Role of mean platelet volume in pregnancy to predict gestational diabetes mellitus in the first trimester

2019 ◽  
Vol 33 (21) ◽  
pp. 3689-3694 ◽  
Author(s):  
Eser Colak ◽  
Emel Ebru Ozcimen ◽  
Mehmet Ufuk Ceran ◽  
Yusuf Aytac Tohma ◽  
Sevsen Kulaksızoglu
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Mean Platelet Volume ◽  
First Trimester ◽  
Platelet Volume ◽  
In Pregnancy

scholarly journals Relationship Between Insulin Resistance and Mean Platelet Volume in Gestational Diabetes Mellitus

2015 ◽  
Vol 7 (02) ◽  
pp. 112-115 ◽  
Author(s):  
Suleyman Baldane ◽  
Suleyman Hilmi Ipekci ◽  
Aysegul Kebapcilar
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Pregnant Women ◽  
Mean Platelet Volume ◽  
Hypoglycemic Agents ◽  
Platelet Volume ◽  
Positive Correlation ◽  
The Relationship

ABSTRACT Objectives: A few studies have investigated the relationship between mean platelet volume (MPV) and gestational diabetes mellitus (GDM), and in these studies the relationship between MPV and insulin resistance has not been analyzed. Our aim in this study was to compare MPV values of the pregnant women with or without GDM and evaluate the relationship between MPV and homeostasis model assessment insulin resistance index (HOMA-IR) in pregnant women. Materials and Methods: One hundred and fourteen with GDM measurements being obtained before any dietary advice or therapy with insulin or hypoglycemic agents were given, and 76 with healthy pregnant women were included the study. Results: In the group with GDM, MPV value was found to be significantly higher than that of the control group (10.2 fl [8.0–12.2] vs. 9.9 fl [5.81–10.9], P = 0.004). HOMA-IR value was detected to be significantly higher in the group with GDM (2.46 [1.5–5.88] vs. 1.30 [0.17–2.92], P < 0.001). A positive correlation between MPV and HOMA-IR was found (r = 0.30, P = 0.002). Conclusion: We have shown that MPV was significantly elevated in GDM patients when compared to healthy pregnant women. Furthermore, we found that there was a positive correlation between MPV and HOMA-IR.

scholarly journals Mean platelet volume in the first trimester as a predictor of gestational diabetes mellitus

2020 ◽  
Vol 133 (11) ◽  
pp. 1364-1365 ◽  
Author(s):  
Zhuo Ren ◽  
Li Lin ◽  
Zhi Li ◽  
Xin-Ping Sun ◽  
Kai Yang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Mean Platelet Volume ◽  
First Trimester ◽  
Platelet Volume

scholarly journals Thrombocyte Alterations in Pregnant Women with Gestational Diabetes Mellitus

2018 ◽  
Vol 24 (1) ◽  
pp. 12 ◽  
Author(s):  
Senol Senturk ◽  
Mehmet Kagitci ◽  
Emine Seda Guvendag Guven
Keyword(s):  
Diabetes Mellitus ◽  
Platelet Count ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Mean Platelet Volume ◽  
Tolerance Test ◽  
Oral Glucose ◽  
Platelet Distribution Width ◽  
Platelet Volume ◽  
Distribution Width

<p><strong>Objective:</strong> Inflammation and its complications might develop in patients diagnosed with diabetes mellitus. It is shown that number, shape and functions of thrombocytes are important for development and prediction of inflammatory process. We aimed to show the changes of number, morphology and functions of platelets in the patients with gestational diabetes mellitus.</p><p><strong>study design:</strong> In a retrospective study, 928 cases in 24-28th weeks of gestation followed regularly in the same clinic were included. We performed 75g oral glucose tolerance test to all cases. Mean platelet volume, platelet distribution width and plateletcrit values of the cases with and without gestational diabetes mellitus according to American Diabetes Association criteria were compared to evaluate the platelet count, morphology, functions and activity.</p><p><strong>Results:</strong> Platelet count and plateletcrit values of cases were significantly higher in the patients with gestational diabetes mellitus. No significant differences were found between the cases with and without gestational diabetes mellitus in mean platelet volume and platelet distribution width values.</p><p><strong>Conclusion:</strong> There is tendency to inflammation in GDM and platelets are part of inflamatuary process in human metabolism. Our findings show that, platelets are affected in GDM. We believe that further studies in this subject will help understanding of pathophysiology of GDM.</p>

Sign in / Sign up

Export Citation Format

Share Document