scholarly journals Relationship between mean platelet volume and vitamin D deficiency in gestational diabetes mellitus

2015 ◽  
Vol 59 (5) ◽  
pp. 448-454 ◽  
Author(s):  
Esra Bahar Gur ◽  
Muammer Karadeniz ◽  
Mine Genc ◽  
Fatma Eskicioglu ◽  
Murat Yalcin ◽  
...  
2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Zhongwei Zhou ◽  
Hongmei Chen ◽  
Mingzhong Sun ◽  
Huixiang Ju

Aim. To evaluate the association between mean platelet volume (MPV) and gestational diabetes mellitus (GDM). Methods. A systematic literature search was performed in PubMed, EMBASE, Web of Science, and The Cochrane Library up to 4 September 2017. Pooled standardized mean differences (SMD) and 95% confidence interval (CI) were calculated using a random-effect model. Results. Nineteen studies comprising 1361 GDM patients and 1911 normal pregnant women were included. MPV was increased in GDM patients when compared with healthy pregnant women (SMD: 0.79; 95% CI: 0.43–1.16; P<0.001). Subgroup analyses revealed that such trend was consistent in the third-trimester (SMD: 1.35; 95% CI: 0.72–1.98), Turkish (SMD: 0.81; 95% CI: 0.43–1.19), and Italian (SMD: 2.78; 95% CI: 2.22–3.34) patients with GDM and the patients diagnosed based on Carpenter and Coustan criteria (SMD: 1.04; 95% CI: 0.42–1.65). Significantly higher MPV also were observed within cross-sectional studies (SMD: 0.99; 95% CI: 0.49–1.49). Remarkable between-study heterogeneity and potential publication bias were observed in this meta-analysis; however, sensitivity analysis indicated that the results were not unduly influenced by any single study. Conclusions. GDM patients are accompanied by increased MPV, strengthening the clinical evidence that MPV may be a predictive marker for GDM.


Author(s):  
Ankita Kumari ◽  
Shaila Mitra ◽  
Harish C Tiwari ◽  
Reena Srivastav

Background: Hypovitaminosis D has been associated with a number of adverse pregnancy outcomes, and has been recognised as a public health concern. The objective of this study was to determine the impact of Vitamin D deficiency on maternal complications like gestational diabetes mellitus (GDM) and preeclampsia (PE) among pregnant women.Methods: This was a case control study undertaken at antenatal clinics and indoor of BRD Medical College, Gorakhpur, Uttar Pradesh, India. Two maternal blood samples, one at <20 weeks and other at term along with cord blood at delivery were taken. Patients were classified into preeclampsia (n=60), gestational diabetes mellitus (n=35) and control group (n=180) after abstracting past medical records at delivery. Vitamin D was estimated by 25- Hydroxyvitamin D125 RIA kit and categorized according to ACOG criteria. Statistical analysis was done by using chi square test, binary logistic regression and Pearson’s correlation coefficient to compare between two variables. P<0.05 was considered statistically significant.Results: Out of 275 women included in the study, 78% of women were Vitamin D deficient. Mean serum vitamin D was significantly lower among preeclamptic women 11.53±6.22 ng/ml and GDM women 12.62±6.69 ng/ml as compared to controls 24.25±14.44 ng/ml (median=18.2 ng/ml) (P<0.05). Vitamin D deficiency was significantly higher in pregnant women GDM (94.28% vs 68.3%) and preeclampsia (96.67% vs 68.3%) when compared to uncomplicated group.Conclusions: Maternal vitamin D deficiency is highly prevalent in early pregnancy and is significantly associated with elevated risk for GDM and preeclampsia.


Hematology ◽  
2008 ◽  
Vol 13 (1) ◽  
pp. 46-48 ◽  
Author(s):  
Alev Akyol Erikçi ◽  
Murat Muhçu ◽  
Özgür Dündar ◽  
Ahmet Öztürk

2018 ◽  
Vol 9 ◽  
Author(s):  
Mansour Amraei ◽  
Safoura Mohamadpour ◽  
Kourosh Sayehmiri ◽  
Seyedeh Fatemeh Mousavi ◽  
Ehsan Shirzadpour ◽  
...  

2013 ◽  
Vol 209 (6) ◽  
pp. 560.e1-560.e8 ◽  
Author(s):  
Geum Joon Cho ◽  
Soon-Cheol Hong ◽  
Min-Jeong Oh ◽  
Hai-Joong Kim

2021 ◽  
Author(s):  
chun yang ◽  
Jing Wu ◽  
Sheng Ge ◽  
Wenguang Sun

Abstract Background This study was to assess vitamin D nutritional status and risk factors among pregnancy of shanghai in China. Methods A cross-sectional study conducted in the Sixth Affiliated People’s Hospital of Shanghai Jiao Tong University. All pregnancy was measured for plasma vitamin D, total blood cholesterol (TCh), high-density lipoprotein (HDL), low-density lipoprotein (LDL) or very-low-density lipoprotein (VLDL) cholesterol and triglycerides, and completed OGTTs test. Age, height, and weight variables came from their electronic medical records. Criteria for vitamin D status were: <12 ng/ml: severe deficiency; 12–19 ng/ml: deficiency; 20–29 ng/ml: insufficiency; 30–50 ng/ml: normal; and > 50 ng/ml (particularly > 60 ng/ml): possibly leading to adverse effects. Vitamin D was measured from December 2016 to April 2017. Results Our study included 953 pregnant women. The mean vitamin D level of pregnancy was 16.06 (range 10.90 to 20.60) ng/ml,and severe vitamin D deficiency was 31.79%(303); vitamin D deficiency was 40.71 %(388); vitamin D insufficiency was 25.08%(239); normal vitamin D was 2.42%(23). Vitamin D deficiency risk factors were age over 30, parity over 2, overweight, obese, gestational diabetes mellitus, and hyperglycemia. Conclusions It is a high prevalence of vitamin D deficiency of Chinese pregnancy in shanghai. Aging more than 30 years, the parity of more than 2, overweight and obesity, gestational diabetes mellitus and hyperglycemia are risk factors for vitamin D deficiency. Public health strategies should focus on the population of pregnancy in shanghai in China.


2019 ◽  
Vol 33 (21) ◽  
pp. 3689-3694 ◽  
Author(s):  
Eser Colak ◽  
Emel Ebru Ozcimen ◽  
Mehmet Ufuk Ceran ◽  
Yusuf Aytac Tohma ◽  
Sevsen Kulaksızoglu

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