The Comparative Metabolism of the Mollicutes (Mycoplasmas): The Utility for Taxonomic Classification and the Relationship of Putative Gene Annotation and Phylogeny to Enzymatic Function in the Smallest Free-Living Cells

1997 ◽  
Vol 23 (4) ◽  
pp. 269-354 ◽  
Author(s):  
J. Dennis Pollack ◽  
Marshall V. Williams ◽  
Ronald N. McElhaney
2018 ◽  
Vol 49 (3) ◽  
pp. 236-243 ◽  
Author(s):  
Catalina Martínez Jaramillo ◽  
Claudia Milena Trujillo Vargas

Bi-allelic mutations in LRBA (from Lipopolysaccharide-responsive and beige-like anchor protein) result in a primary immunodeficiency with clinical features ranging from hypogammaglobulinemia and lymphoproliferative syndrome to inflammatory bowel disease and heterogeneous autoimmune manifestations. LRBA deficiency has been shown to affect vesicular trafficking, autophagy and apoptosis, which may lead to alterations of several molecules and processes that play key roles for immunity. In this review, we will discuss the relationship of LRBA with the endovesicular system in the context of receptor trafficking, autophagy and apoptosis. Since these mechanisms of homeostasis are inherent to all living cells and not only limited to the immune system and also, because they are involved in physiological as well as pathological processes such as embryogenesis or tumoral transformation, we envisage advancing in the identification of potential pharmacological agents to manipulate these processes.


2017 ◽  
Vol 49 (5) ◽  
pp. 467-481 ◽  
Author(s):  
Robert LÜCKING ◽  
R. Greg THORN ◽  
Irja SAAR ◽  
Michele D. PIERCEY-NORMORE ◽  
Bibiana MONCADA ◽  
...  

AbstractMolecular studies have shown the type collection of Omphalina oreades to be conspecific with a small brown basidiolichen from the Appalachian range in Newfoundland, both with 4-spored basidia. Two sequences deposited in GenBank, originally identified as O. grisella, fell in the same clade. Sequences of the type collection of Omphalia grisella, with 2-spored basidia, formed a sister clade together with two GenBank deposits, one identified as O. grisella and the other as Omphalina velutina. Omphalina oreades is recombined here as Lichenomphalia oreades comb. nov., and the species redescribed and illustrated. Sequences of the internal transcribed spacer regions of nuclear ribosomal DNA (ITS rDNA) from the algae associated with two collections of L. oreades fell within a highly supported clade with members of an undetermined species of Coccomyxa. The most abundant algal ribosomal large subunit sequence from granules at the base of a different collection matched GenBank sequences identified as Chloroidium ellipsoideum, which is probably either a free-living algal species or a partner to a species of Trapeliopsis. The second most abundant sequence matched Coccomyxa subellipsoidea and is the most likely photobiont of L. oreades. Further studies are required to elucidate the relationship of L. velutina to these taxa.


1954 ◽  
Vol 2 (3) ◽  
pp. 325 ◽  
Author(s):  
HT Clifford ◽  
FE Binet

From measurements of fruit lengths, fruit weights, and lengths of fruiting umbels of trees from the species Eucalyptus elaeophora and E. goniocalyx and their presumed hybrid swarm, a formula is calculated for taxonomic classification using statistical discriminant theory. The rates of misclassification expected with the use of this formula are estimated. A simple geometrical model of the relationship of the species and the hybrid is investigated.


2000 ◽  
Vol 6 (S2) ◽  
pp. 836-837
Author(s):  
David L. Spector

Green fluorescent protein (GFP) and its variants have become powerful tools with which to study the dynamics of many fundamental processes in living cells. I will first discuss the advantages of GFP and important parameters that one must consider in performing live-cell microscopy experiments including how to keep cells happy on the microscope stage. I will then go on to discuss work from our laboratory using multiple microscopic approaches to address questions related to gene expression.Many of the basic processes that are essential for normal cell growth and division are regulated in the nucleus, ie. DNA replication, transcription, RNA processing and transport. The organization of these functions in the nucleus must be highly controlled in order to enable cells and/or the entire organism to function properly. However, relatively little has been known about the relationship of nuclear organization to gene expression.


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