Instruction of feeding methods to Japanese pregnant women who cannot be confirmed as HTLV-1 carrier by western blot test

2013 ◽  
Vol 27 (13) ◽  
pp. 1392-1393 ◽  
Author(s):  
Shunji Suzuki ◽  
Masanobu Tanaka ◽  
Hideo Matsuda ◽  
Yuki Tsukahara ◽  
Yasushi Kuribayashi ◽  
...  
2020 ◽  
Vol 35 (3) ◽  
pp. 277-280
Author(s):  
Nathan Mise ◽  
Mayumi Ohtsu ◽  
Akihiko Ikegami ◽  
Yoko Hosoi ◽  
Yoshihiko Nakagi ◽  
...  

AbstractObjectivesExposure to inorganic arsenic (iAs) is a world-wide health concern. We reported that Japanese children and pregnant women are exposed to moderate levels of iAs through food. Reducing iAs contamination from foods of high iAs is an important issue unique in Japan. Integrated iAs is methylated to less toxic organic forms, and S-adenosyl-L-methyonine (SAM), a common methyl-donor of DNA and histones, is utilized in this process. Chronic consumption of SAM by iAs metabolism due to exposure to iAs might alter the epigenetic modification of genome. The SAM biosynthesis pathway is dependent on folate cycle, and it is possible that ingestion of sufficient folic acid (FA) is protective to iAs induced toxicity.MethodsIn the course of our cross-sectional body burden analyses of Pb and iAs in Japanese children and pregnant women, termed “PbAs study”, FA concentration in serum of 104 pregnant women was measured.ResultsMean (±SEM) of serum FA concentration was 15.8 ± 1.3 (ng/mL). There are significant number of people showing very high FA (>30 ng/ mL), and large fraction of them were taking supplements daily.ConclusionsThese results suggested that level of FA ingestion of Japanese pregnant women is high for supporting normal fetal development.


2005 ◽  
Vol 15 (2) ◽  
pp. 203-206 ◽  
Author(s):  
Ying Ji ◽  
Yukie Nakai ◽  
Omar Marianito Maningo Rodis ◽  
Naoyuki Kariya ◽  
Seishi Matsumura ◽  
...  

2018 ◽  
Vol 33 (12) ◽  
pp. 2017-2022
Author(s):  
Junichi Hasegawa ◽  
Seiji Wada ◽  
Atsushi Kasamatsu ◽  
Masamitsu Nakamura ◽  
Haruka Hamanoue ◽  
...  

2016 ◽  
Vol 23 (4) ◽  
pp. 570-575 ◽  
Author(s):  
Jacek Sroka ◽  
Angelina Wójcik-Fatla ◽  
Violetta Zając ◽  
Anna Sawczyn ◽  
Ewa Cisak ◽  
...  

1994 ◽  
Vol 5 (6) ◽  
pp. 409-414 ◽  
Author(s):  
H Young ◽  
P J Walker ◽  
D Merry ◽  
A Mifsud

A prototype Western blot kit was evaluated as a confirmatory test for syphilis using 131 sera characterized by other serological tests for syphilis. There were 114 treponemal sera (including 94 cases of early syphilis, 83 of which were untreated) and 17 non-treponemal problem sera (11 gave false positive reactions on screening with the TmpA recombinant antigen enzyme immunoassay (EIA), 3 gave false positive fluorescent treponemal antibody absorbed (FTA-abs) tests, and 3 false positive Captia Syphilis G EIA results). Based on the manufacturer's criteria of reactivity in multiple bands for designating a positive result the Western blot test gave a sensitivity of 99.1% (113/114) and a specificity of 88.2% (15/17) when indeterminate reactions were scored positive and 98.2% (112/114) and 100% (17/17) when indeterminate reactions were scored negative. Sensitivity was high in both treated and untreated infection. Corresponding sensitivities for the TPHA and FTA-abs when equivocal reactions were scored negative were 97.5% (111/114) and 99.1% (113/114). The high sensitivity of the FTA-abs in this study is probably due to the large number of untreated primary infections. Our results with the Western blot, confirm earlier studies using ‘in-house’ test systems and, support a role for a commercial Western blot test in the confirmatory diagnosis of syphilis. Further studies are required to confirm the high specificity and sensitivity of the kit in a larger series including a wider variety of non-treponemal cases as well as patients with untreated and treated infection.


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