scholarly journals Chemical composition, antimicrobial and free radical scavenging activities of Grewia pubescens

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Free Radical ◽  
Ethyl Acetate ◽  
Radical Scavenging ◽  
Fats And Oils ◽  
Free Radical Scavenging ◽  
Rhizopus Stolonifer ◽  
Penicillium Notatum ◽  
Methanol Extracts ◽  
Gas Chromatography Mass Spectroscopy ◽  
Free Radical Scavenging Activities

The phytochemical screening of n-hexane, ethyl acetate and methanol extracts of Grewia pubescens leaves showed the presence of alkaloids, steroids, terpenoids, flavonoids, saponins, anthraquinones, tannins, glycosides and fats and oils. The three extracts were tested on six bacterial and four fungal strains, and exhibited satisfactory inhibitory activities against Staphylococcus aureus, Escherichia coli, Bacillus subtilis, Pseudomona aeruginosa, Salmonella typhii, Klebsiellae pneumonae, Candida albicans, Aspergillus niger, penicillium notatum and Rhizopus stolonifer, except ethyl acetate extract which showed no antifungal property on penicillium notatum and Rhizopus stolonifer. Methanol extract of the plant possessed significant antioxidant activity by exhibiting DPPH free radical scavenging property with IC50 of 10.26 μM, using DPPH antioxidant assay. The compounds present in the extracts were characterised using Gas chromatography-Mass spectroscopy (GC-MS). Seven, three and six compounds were revealed in n-hexane, ethyl acetate and methanol extracts of Grewia pubescens leaves respectively, while hexadecanoic acid is the most abundant constituent in all three extracts with corresponding percentage of abundance of 47.92, 53.20 and 61.59.

scholarly journals In vitro inhibitory potential of avocado fruits, Persea americana (Lauraceae) against oxidation, inflammation and key enzymes linked to skin diseases

2021 ◽  
Vol 69 (2) ◽  
Author(s):  
Muhammed M. Hürkul ◽  
Sezen Yilmaz Sarialtin ◽  
Ayşegül Köroğlu ◽  
Tülay Çoban
Keyword(s):  
Lipid Peroxidation ◽  
Free Radical ◽  
Skin Diseases ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Persea Americana ◽  
Methanol Extracts ◽  
Hexane Extracts ◽  
Anti Inflammatory ◽  
Free Radical Scavenging Activities

Avocado (Persea americana Mill.) is a member of Lauraceae with one-seeded berry fruit and cultivated in all tropical, subtropical regions in the world and in the Southern coast region of Turkey. Oxidative damage caused by UV can trigger inflammation, resulting in serious inflammatory skin diseases including eczema, seborrheic dermatitis, hyperpigmentation and ageing. Enzyme inhibitors involved in melanogenesis, such as tyrosinase, have been used recently for hyperpigmentation and skin diseases in cosmetic products. Objective: This study aimed to evaluate the antioxidant, anti-inflammatory, anti-tyrosinase activities and total polyphenolic contents of the different parts of P. americana fruit. Methods: The fruit was divided into exocarp, mesocarp, seed, and then methanol and n-hexane extracts were prepared. DPPH and ABTS free radical scavenging capacities and inhibitory potentials on lipid peroxidation were determined to investigate the antioxidant potentials of the extracts. Anti-inflammatory activities of the extracts were evaluated by measuring the stabilization level of the human red blood cell membrane. The tyrosinase inhibitory activities of the samples were determined using mushroom tyrosinase. Results: In general methanol extracts possessed remarkable higher DPPH free radical scavenging activities than n-hexane extracts. The highest activity was determined in methanol extracts of seed (4.17 ± 0.04 mg/mL) followed by exocarp (5.25 ± 0.05 mg/mL). Overall methanol extracts possessed higher ABTS free radical scavenging activities than n-hexane extracts. The greatest ABTS free radical scavenging activity was obtained in methanol extracts of seed (0.03 ± 0.01 mg/mL). In the anti-lipid peroxidation assay, the greatest activity was noticed in methanol extracts of seed (7.71 ± 0.36 µg/mL) followed by exocarp (12.12 ± 0.34 µg/mL), while all n-hexane extracts were inactive. Overall methanol extracts exhibited higher anti-inflammatory and antioxidant properties than n-hexane extracts. However, the maximum anti-tyrosinase activity was determined in n-hexane extracts of exocarp (0.40 ± 0.01 mg/mL) followed by seed (0.46 ± 0.01 mg/mL). Conclusions: These extracts are promising candidates for use as natural products-based antioxidant and anti-inflammatory properties in inflammation-related disease, and also anti-tyrosinase properties in dermatological applications.

Antimicrobial and free radical scavenging activities of crude extract and fractions from the tuberous root of Mirabilis jalapa L.

2012 ◽  
Vol 2 (5) ◽  
pp. 209-216
Author(s):  
J. Gogoi ◽  
K. S. Nakhuru ◽  
A. K. Rai ◽  
P. Chattophadhayay ◽  
H. K. Gogoi ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Free Radical ◽  
Ethyl Acetate ◽  
Radical Scavenging ◽  
Amyl Alcohol ◽  
Free Radical Scavenging ◽  
Tuberous Root ◽  
Diffusion Method ◽  
Mirabilis Jalapa ◽  
Free Radical Scavenging Activities

Mirabilis jalapa L. belonging to family Nyctaginaceae is a widely used traditionalmedicinal plant in different parts of the world. In present study, aqueous methanolic extract and fractions from tuberous root of M. jalapa were evaluated for antimicrobial and free radical scavenging activities. The tuberousroot was extracted in 80 % methanol. Phytochemical constituents were tested following standard procedures which revealed the presence of terpenoids, flavonoids, tannins, steroids, phenolic compounds and alkaloids. The dried extract was further fractionated by using solvents chloroform, ethyl acetate, amyl alcohol, methanol and water. Free radical scavenging capacity was evaluated by 2, 2 diphenyl 1 picrylhydrazine (DPPHô€ˆ©Ë™) and 2, 2’–azinobis (3‐ethylbenzothiazoline‐6‐sulfonic acid) (ABTS+) assays. IC50 values of extractwere 60±0.71μg/ml and 80±0.56 μg/ml with DPPH and ABTS assays, respectively. Ethyl acetate and amyl alcohol fractions exhibited strong antioxidant activity among the fractions. Antimicrobial activity of extract and fractions was evaluated against selected human pathogens such as Staphylococcus aureus, Streptococcus mutans, Escherchia coli and Candida albicans by agar well diffusion method. The extract and fractions were most active against S. mutans and E. coli. The present study indicated that the root of M. jalapa possess potential antioxidant and broad spectrum antimicrobial activity which could be explored for pharmaceutical applications.

Anti-Acne Inducing Bacteria and Free Radical Scavenging Activities of Turmeric Rhizome Extracts Prepared Using Different Solvents

2017 ◽  
Author(s):  
R Nurficahyanti ◽  
P Charoenwiwattanakij ◽  
R Wattanalai ◽  
W Pothitirat
Keyword(s):  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activities

Antioxidant and Free Radical Scavenging Activities of Culinary-Medicinal Mushrooms, Golden Chanterelle Cantharellus cibarius and Angel's Wings Pleurotus porrigens

2010 ◽  
Vol 12 (3) ◽  
pp. 265-272 ◽  
Author(s):  
Mohammad Ali Ebrahimzadeh ◽  
Seyed Mohammad Nabavi ◽  
Seyed Fazel Nabavi ◽  
Shahram Eslami
Keyword(s):  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Medicinal Mushrooms ◽  
Free Radical Scavenging Activities

Free Radical Scavenging Activity of Methanol Extracts of Chungkukjang

2008 ◽  
Vol 13 (2) ◽  
pp. 77-83 ◽  
Author(s):  
Kyoung-Chun Seo ◽  
Jeong-Sook Noh ◽  
Na-Ri Yi ◽  
Ji-Myung Choi ◽  
Eun-Ju Cho ◽  
...  
Keyword(s):  
Free Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity ◽  
Methanol Extracts

MICROWAVE-ASSISTED SEED ESSENTIAL OIL OF ELEUTHEROCOCCUS SENTICOSUS AND ITS ANTIOXIDANT AND FREE RADICAL-SCAVENGING ACTIVITIES

2012 ◽  
Vol 37 (1) ◽  
pp. 119-127 ◽  
Author(s):  
VIVEK K. BAJPAI ◽  
AJAY SHARMA ◽  
SUNG HONG KIM ◽  
YONGHO KIM ◽  
JONG-JOO KIM ◽  
...  
Keyword(s):  
Free Radical ◽  
Essential Oil ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Eleutherococcus Senticosus ◽  
Microwave Assisted ◽  
Free Radical Scavenging Activities

scholarly journals On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK

2012 ◽  
Vol 54 (3) ◽  
pp. 245-257 ◽  
Author(s):  
Annia Galano ◽  
Dun Xian Tan ◽  
Russel J. Reiter
Keyword(s):  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activities
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