Impact of Acceptance and Body Compassion in Endometrial Cancer

2019 ◽  
Author(s):  
Stefanie Denu

Objective: This study explored the predictive role of body-related components, such as body compassion and body mass index, and components of the Acceptance and Commitment Therapy (ACT) model, such as mindfulness and experiential avoidance, on the experience of pain and quality of life quality of life in endometrial cancer survivors.Methods: Surveys were sent to members of a national online support group for endometrial cancer patients who had completed treatment. The study included 82 total participants.Results: ACT components and body-related components, as a set, predicted pain interference and quality of life but not pain severity. Experiential avoidance was determined to be an independent predictor of quality of life. Negative affect, used as a covariate, independently predicted unique variance in pain severity, pain interference, and quality of life. Age was an independent predictor of pain interference and quality of life. Lastly, obese endometrial cancer survivors endorsing higher experiential avoidance, lower mindfulness, and lower body compassion compared to non-obese endometrial cancer survivors.Conclusions: Body-related and ACT components, taken together, may be predictive of pain interference and quality of life, while experiential avoidance may contribute uniquely to quality of life, rendering it a key target of future intervention for endometrial cancer survivors post-treatment.

2017 ◽  
Vol 33 (4) ◽  
pp. 857-864 ◽  
Author(s):  
Alexander R. Lucas ◽  
Brian C. Focht ◽  
David E. Cohn ◽  
Maryanna D. Klatt ◽  
Janet Buckworth

2019 ◽  
Vol 29 (3) ◽  
pp. 531-540 ◽  
Author(s):  
Dimitrios A Koutoukidis ◽  
Rebecca J Beeken ◽  
Ranjit Manchanda ◽  
Matthew Burnell ◽  
Nida Ziauddeen ◽  
...  

ObjectivesTo explore the effectiveness of a theory-based behavioral lifestyle intervention on health behaviors and quality of life in endometrial cancer survivors.’MethodsThis was a secondary analysis of a randomized controlled pilot trial conducted in two UK hospitals enrolling disease-free stage I-IVA endometrial cancer survivors. Participants were allocated to an 8-week group-based healthy eating and physical activity intervention or usual care using 1:1 minimization. Participants were followed up at 8 and 24 weeks, with the 8-week assessment being blinded. Diet, physical activity, and quality of life were measured with the Alternative Healthy Eating Index 2010, Stanford 7-Day Physical Activity Recall, and the EORTC Quality of life Questionnaire Core 30, respectively. We analyzed all eligible participants using the intention-to-treat approach in complete cases, adjusting for baseline values, body mass index, and age.ResultsWe enrolled 60 of the 296 potentially eligible endometrial cancer survivors (May - December 2015). Fifty-four eligible participants were randomized to the intervention (n=29) or usual care (n=31), and 49 had complete follow-up data (n=24 in the intervention and n= 25 in usual care). Intervention adherence was 77%. At 8 weeks, participants in the intervention improved their diet compared to usual care (difference in Alternative Healthy Eating Index 2010 score 7.5 (95% CI: 0.1 to 14.9), P=0.046) but not their physical activity (0.1 metabolic equivalent-h/day 95% CI: (-1.6 to 1.8), P=0.879), or global quality of life score (5.0 (95% CI: -3.4 to 13.3), P=0.236). Global quality of life improved in intervention participants at 24 weeks (difference 8.9 (95% CI: 0.9 to 16.8), P=0.029). No intervention-related adverse events were reported.ConclusionsThe potential effectiveness of the intervention appeared promising. A future fully-powered study is needed to confirm these findings.Trial registration numberNCT02433080.


2014 ◽  
Vol 132 (1) ◽  
pp. 137-141 ◽  
Author(s):  
Anke Smits ◽  
Alberto Lopes ◽  
Nagindra Das ◽  
Ruud Bekkers ◽  
Khadra Galaal

2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Michael C. Robertson ◽  
Elizabeth J. Lyons ◽  
Jaejoon Song ◽  
Matthew Cox-Martin ◽  
Yisheng Li ◽  
...  

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. e20635-e20635
Author(s):  
Grecory Tsoukalas ◽  
Alexandros Tzovaras ◽  
Nikolaos Tsoukalas ◽  
Sofia Stamatopoulou ◽  
George Gatsos ◽  
...  

e20635 Background: Osseous metastases in patients suffering from cancer, is a multifactor symptom which affects quality of life. Methods: The Samarium group (SG) n=53 patients received a single bolus infusion of (153)Sm (37 MBq/kg), and we compared with a Control group(CG) n=37. Both groups of patients who had metastatic bone cancer requiring analgesia answered the following questionnaires: Greek Brief Pain Inventory (GBPI), Brief Multidimensional Life Satisfaction Scale (BMLSS), Hospital Anxiety Depression Scale (HADS), ECOG/WHO/Zubrod score and Hospital Satisfaction Scale (HSS),day 0 and 30±3 days after the intervention start.There was no statistically significant(SS) difference for the variables(V-) sex, age, pain’s localization and lodging. Results: Pain severity and pain interference change over time was the same for both groups P= 0.0005. For the V- HADS-anxiety, SG showed no SS improvementP= 0.397, something which was achieved for the CG,P= 0.031. The V- HADS improved SS for both groups P= 0.031 and P= 0.003 respectively which changed over time with the same way. This may show the strong relation between pain and depression. The V- ECOG also changed over time in the same way for both SG(P=0.005) and CG (P=0.014). The percentage of patients who changed scale towards improvement for their quality of life was 24,3% for the CG and 15,1% for the SG. The V-BMLSS change over time was similar for both groups. There was no SS difference for the V-HSS towards medical and nursing personnel for both groups (P=1.000). Myelotoxicity for the SG was moderate and reversible, as well as the side effects for the CG. Finally an equivalence test between the two groups, showing that both treatment regimens were equivalent for all variables: Pain severity=0.034, Pain interference=0.009, HAD-anxiety P=0.048, HAD-depression=0.033, BMLSS=0.016, ECOG=0.0005. During our study among the patients of the SG in some cases the stabilization of bone lesions was observed, and in one case partial and/or complete remission. Conclusions: Administration of (153)Sm is another equivalent option for those patients who are intolerant or resistant to medication treatment having a better cost-effectiveness result.


2011 ◽  
Vol 121 (1) ◽  
pp. 169-173 ◽  
Author(s):  
Meike Becker ◽  
Tetyana Malafy ◽  
Michaela Bossart ◽  
Karl Henne ◽  
Gerald Gitsch ◽  
...  

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