scholarly journals Test-retest reliability of an adaptive thermal pain calibration procedure in healthy volunteers

2021 ◽  
Author(s):  
Carolyn Amir ◽  
Margaret Rose-McCandlish ◽  
Rachel Weger ◽  
Troy C. Dildine ◽  
Dominik - Mischkowski ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Time Windows ◽  
Calibration Procedure ◽  
Pain Tolerance ◽  
Small Samples ◽  
Intra Class Correlation ◽  
Thermal Pain ◽  
Pain Ratings ◽  
Stimulus Offset ◽  
Test Retest Reliability

Quantitative sensory testing (QST) allows researchers to evaluate associations between noxious stimuli and acute pain in clinical populations and healthy participants. Despite its widespread use, our understanding of QST’s reliability is limited, as reliability studies have used small samples and restricted time windows. We examined the reliability of pain ratings in response to noxious thermal stimulation in 171 healthy volunteers (n = 99 female, n = 72 male) who completed QST on multiple visits ranging from 1 day to 952 days between visits. On each visit, participants underwent an adaptive pain calibration in which they experienced 24 heat trials and rated pain intensity after stimulus offset on a 0-10 Visual Analog Scale. We used linear regression to determine pain threshold, pain tolerance, and the correlation between temperature and pain for each session and examined the reliability of these measures. Threshold and tolerance were moderately reliable (Intra-class correlation [ICC]=0.66 and 0.67, respectively; p<.001), whereas temperature-pain correlations had low reliability (ICC=0.23). In addition, pain tolerance was significantly more reliable in female participants than male participants, and we observed similar trends for other pain sensitive measures. Our findings indicate that threshold and tolerance are largely consistent across visits, whereas sensitivity to changes in temperature vary over time and may be influenced by contextual factors.

scholarly journals The Influence of Maximal Strength and Knee Angle on the Reliability of Peak Force in the Isometric Squat

Sports ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. 140
Author(s):  
Arthur E. Lynch ◽  
Robert W. Davies ◽  
Philip M. Jakeman ◽  
Tim Locke ◽  
Joanna M. Allardyce ◽  
...  
Keyword(s):  
Peak Force ◽  
Knee Angle ◽  
Force Output ◽  
Reliable Measure ◽  
Intra Class Correlation ◽  
Retest Reliability ◽  
Test Retest Reliability ◽  
Intra Class Correlation Coefficient ◽  
Acceptable Reliability ◽  
Maximal Effort

This study aimed to investigate the test-retest reliability of peak force in the isometric squat across the strength spectrum using coefficient of variation (CV) and intra-class correlation coefficient (ICC). On two separate days, 59 healthy men (mean (SD) age 23.0 (4.1) years; height 1.79 (0.7) m; body mass 84.0 (15.2) kg) performed three maximal effort isometric squats in two positions (at a 120° and a 90° knee angle). Acceptable reliability was observed at both the 120° (CV = 7.5 (6.7), ICC = 0.960 [0.933, 0.977]) and 90° positions (CV = 9.2 (8.8), ICC = 0.920 [0.865, 0.953]). There was no relationship between peak force in the isometric squat and the test-retest reliability at either the 120° (r = 0.052, p = 0.327) or 90° (r = 0.014, p = 0.613) positions. A subgroup of subjects (n = 17) also completed the isometric squat test at a 65° knee angle. Acceptable reliability was observed in this position (CV = 9.6 (9.3), ICC = 0.916 [0.766, 0.970]) and reliability was comparable to the 120° and 90° positions. Therefore, we deem isometric squat peak force output to be a valid and reliable measure across the strength spectrum and in different isometric squat positions.

scholarly journals Guideline for Selecting Types of Reliability and Suitable Intra-class Correlation Coefficients in Clinical Research

2021 ◽  
Author(s):  
Khalil Taherzadeh Chenani ◽  
Farzan Madadizadeh
Keyword(s):  
Clinical Research ◽  
Correlation Coefficients ◽  
Reliability Test ◽  
Research Information ◽  
Rater Reliability ◽  
Intra Class Correlation ◽  
Medical Researchers ◽  
Different Types ◽  
Test Retest Reliability ◽  
Cluster Correlation

Introduction: Reliability is an integral part of measuring the reproducibility of research information. Intra-cluster correlation coefficient (ICC) is one of the necessary indicators for reliability reporting, which can be misleading in terms of its diversity. The main purpose of this study was to introduce the types of reliability and appropriate ICC indices.  Methods: In this tutorial article, useful information about the types of reliability and indicators needed to report the results, as well as the types of ICC and its applications were explained for dummies. Results: Three general types of reliability include inter-rater reliability, test-retest reliability, and intra-rater reliability was presented. 10 different types of ICC were also introduced and explained. Conclusion: The research results may be misleading if any of the reliability types and calculation criteria types are chosen incorrectly. Therefore, to make the results of the study more accurate and valuable. Medical researchers must seek help from relevant guidelines such as this study before conducting reliability analysis.  

scholarly journals Relationships between Irritable Bowel Syndrome Pain, Skin Temperature Indices of Autonomic Dysregulation, and Sensitivity to Thermal Cutaneous Stimulation

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Fong Wong ◽  
Anthony C. Rodrigues ◽  
Christopher D. King ◽  
Joseph L. Riley ◽  
Siegfried Schmidt ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Pain Sensitivity ◽  
Thermal Hyperalgesia ◽  
Thermal Stimulation ◽  
Thermal Pain ◽  
Pain Ratings ◽  
Irritable Bowel ◽  
Thermal Pain Sensitivity ◽  
Pain Patients ◽  
Skin Temperatures

This study evaluated relationships between irritable bowel syndrome (IBS) pain, sympathetic dysregulation, and thermal pain sensitivity. Eight female patients with diarrhea-predominant IBS and ten healthy female controls were tested for sensitivity to thermal stimulation of the left palm. A new method of response-dependent thermal stimulation was used to maintain pain intensity at a predetermined level (35%) by adjusting thermal stimulus intensity as a function of pain ratings. Clinical pain levels were assessed prior to each testing session. Skin temperatures were recorded before and after pain sensitivity testing. The temperature of palmar skin dropped (1.5) when the corresponding location on the opposite hand of control subjects was subjected to prolonged thermal stimulation, but this response was absent for IBS pain patients. The patients also required significantly lower stimulus temperatures than controls to maintain a 35% pain rating. Baseline skin temperatures of patients were significantly correlated with thermode temperatures required to maintain 35% pain ratings. IBS pain intensity was not significantly correlated with skin temperature or pain sensitivity. The method of response-dependent stimulation revealed thermal hyperalgesia and increased sympathetic tone for chronic pain patients, relative to controls. Similarly, a significant correlation between resting skin temperatures and thermal pain sensitivity for IBS but not control subjects indicates that tonic sympathetic activation and a thermal hyperalgesia were generated by the chronic presence of visceral pain. However, lack of a significant relationship between sympathetic tone and ratings of IBS pain casts doubt on propositions that the magnitude of IBS pain is determined by psychological stress.

Test–retest reliability of pain location using three different body chart grids: a study on healthy volunteers

Physiotherapy ◽  
2015 ◽  
Vol 101 ◽  
pp. e860
Author(s):  
D. Leoni ◽  
C. Cescon ◽  
H. Carolin ◽  
G. Capra ◽  
R. Clijsen ◽  
...  
Keyword(s):  
Healthy Volunteers ◽  
Retest Reliability ◽  
Pain Location ◽  
Test Retest Reliability

Distraction and Redefinition in the Reduction of Low and High Intensity Experimentally-Induced Pain

1987 ◽  
Vol 7 (2) ◽  
pp. 155-164 ◽  
Author(s):  
Debora L. Dubreuil ◽  
Norman S. Endler ◽  
Nicholas P. Spanos
Keyword(s):  
Short Duration ◽  
High Intensity ◽  
Pain Tolerance ◽  
Pressure Pain ◽  
Low Intensity ◽  
Pain Ratings ◽  
Lower Pain ◽  
Intensity Condition ◽  
Experimentally Induced

Subjects underwent either low intensity or high intensity acute focal pressure pain of relatively short duration on a baseline and posttest trial. On the posttest subjects in each intensity condition either engaged in distraction (shadowing letters), attended to sensations (redefinition) or were given no treatment (controls). Distraction was more effective than redefinition at reducing rated pain and at enhancing pain tolerance for subjects in the high intensity condition. Subjects who scored as repressors gave lower pain ratings than sensitizers. Moreover, in the high intensity condition repressors given distraction reported significant increases in pain tolerance while sensitizers given distraction showed no changes in tolerance.

Transient Analgesia Evoked by Noxious Stimulus Offset

2002 ◽  
Vol 87 (4) ◽  
pp. 2205-2208 ◽  
Author(s):  
Joshua D. Grill ◽  
Robert C. Coghill
Keyword(s):  
Chronic Pain ◽  
Pain Intensity ◽  
Relative Proportion ◽  
Noxious Stimulus ◽  
Temporal Contrast ◽  
Nociceptive Processing ◽  
Perceived Pain ◽  
Pain Ratings ◽  
Stimulus Offset ◽  
Escape Behaviors

Pain has long been thought to wax and wane in relative proportion to fluctuations in the intensity of noxious stimuli. Dynamic aspects of nociceptive processing, however, remain poorly characterized. Here we show that small decreases (±1–3°C) in noxious stimulus temperatures (47–50°C) evoked changes in perceived pain intensity that were as much as 271% greater than those of equal magnitude increases. These decreases in perceived pain intensity were sufficiently large to be indistinguishable from those evoked by 15°C decreases to clearly innocuous levels. Furthermore, decreases in pain ratings following noxious stimulus offset were significantly greater than those occurring during adaptation to constant temperature stimuli. Together, these findings indicate that an analgesic mechanism is activated during noxious stimulus offset. This analgesic phenomenon may serve as a temporal contrast enhancement mechanism to amplify awareness of stimulus offset and to reinforce escape behaviors. Disruption of this mechanism may contribute importantly to chronic pain.

Paradoxical differences in pain ratings of the same stimulus intensity

2017 ◽  
Vol 16 (1) ◽  
pp. 181-181
Author(s):  
M.E. McPhee ◽  
K.K. Petersen ◽  
M.S. Hoegh ◽  
T. Graven-Nielsen
Keyword(s):  
Stimulus Intensity ◽  
Analogue Scale ◽  
Temporal Summation ◽  
Pain Tolerance ◽  
Pain Rating ◽  
Baseline Assessment ◽  
Identical Stimulus ◽  
Pain Ratings ◽  
Pain Detection ◽  
Stimulation Paradigm

Abstract Aims Stimulus intensity used for assessing temporal summation of pain (TSP) is commonly set at the participants’ pain tolerance. Yet pain ratings during TSP rarely reach that initial pain tolerance pain rating. This study aimed to explore the differences between baseline pain tolerance assessed by cuff algometry and subsequent pain ratings of the same stimulus intensity, and the reliability of these ratings over 2 sessions. Methods In two sessions, separated by one week, 24 healthy, pain-free males had their pressure pain detection (PDT) and tolerance threshold (PTT) recorded using a staircase inflation paradigm (5 kPa increments, 1sec-ON:4sec-OFF) with a cuff algometry system. The pain intensity was assessed during cuff stimulation using an electronic visual analogue scale (VAS, 0–10 cm). Three different inflation paradigms were then performed, using the PTT level as stimulation intensity, and a 1-s duration for each stimulus: PEAKS: 3 inflations at 0.17 Hz, SLOW: 10 inflations at 0.01 Hz, FAST: 10 inflations at 0.5 Hz). Approximately 5-min was kept between the staircase assessment and the first stimulation paradigm, and between each of the 3 inflation paradigms. The PTT and first inflation VAS rating from each paradigm was extracted. Results The VAS rating of PTT pressure was higher in the staircase (VAS: 8.5±2.1 cm) than the first PPT stimulus in any other paradigm (PEAKS: 5.4±2.0; SLOW: 4.6±2.1; FAST: 4.0±2.3, P < 0.05). VAS ratings were also lower in each subsequent paradigm (i.e. PEAKS > SLOW > FAST, P < 0.05). Intra-class coefficients demonstrated excellent reliability for each paradigm (all ICC > 0.79) between sessions. Conclusions PTT, as assessed with the staircase inflation paradigm, was rated more painful during baseline assessment than when the identical stimulus profile (PPT intensity for 1-s) was applied afterwards and this finding is considered reliable.

Sign in / Sign up

Export Citation Format

Share Document