Efficacy and safety of herbal medicines external application with Tuina in congenital muscular torticollis : A systematic review and meta-analysis protocol

Review question / Objective: By 3 to 4 months of age, infants can keep their necks upright and look into both eyes horizontally. But infants with CMT have a wry neck also known as a twisted neck. Complementary therapies have been commonly used to treat CMT, such as tuina, acupuncture, herbal medicine. Among them, external application of herbal medicine is non-surgical and non-invasive inventions so it can be used widely in East Asia. This review aims to evaluate any form of external application of herbal medicines in CMT, such as cream, oil, extract, form of patch, etc. Information sources: We will electronically search the following database 4 English databases(MEDLINE, PubMed, EMBASE, the Cochrane Central Register of Controlled Trials), 3 Chinese databases(China National Knowledge Infrastructure(CNKI), Chinese Scientific Journal Database(VIP), Wan Fang Database), 4 Korean medical databases(Oriental Medicine Advanced Searching Integrated System(OASIS), Korean Studies Information Service System(KISS), National Digital Science Links(NDSL), Research Information Sharing Service(RISS)) from their founding date to June 2022, without any language restrictions.

Applied Behavior Analysis as Treatment for Autism Spectrum Disorders: Topic Modeling and Linguistic Analysis of Reddit Posts

Background: It is critical for professionals to understand the discourse landscape within various online and social media outlets in order to support families of children with autism in treatment decision-making. This need is heightened when considering treatments that have garnered excitement and controversy, such as applied behavioral analysis (ABA) therapy.Method: The specific aims of this study were to identify the main themes in Reddit posts about ABA-based interventions for autism using topic modeling, to examine the linguistic aspects of Reddit conversations using the Linguistic Inquiry and Word Count (LIWC) analysis, and to examine the relationship between linguistic aspects and user category (i.e., pro- vs. anti-ABA vs. undecided, parent vs. professional vs. an individual with autism).Results: The topic modeling resulted in 11 themes that ranged across various elements, such as autism as a condition and its management, stakeholders, and consequences of autism and the support needed. The posts of individuals were focused on personal experiences and opinions as opposed to clinical and research information sharing. Linguistic analysis indicated that the posts reveal an intimate stance rather than an empirical stance.Conclusions: Results provide insight into perspectives of ABA. This type of research may help in developing and distributing appropriate and evidence-based information.

Innovative technology of information analysis of electrocardiosignals for the purpose of diagnostics of diseases of internal organs at any stage of their development

Given the results of years of research information on the properties of electrocardiosignals, set their properties, characteristic of the impulse nature, the proposed methods of information analysis of electrocardiosignals to diagnose diseases of internal organs at any stage of development, protected by patents of the Russian Federation. The main stages of the technology of information analysis of electrocardiosignals for the purpose of diagnostics of diseases of internal organs are described. The rationale for the diagnosis of these diseases at any stage of their development is given. Data were obtained according to which targeted therapeutic and preventive measures at the initial stage of disease development can provide effective prevention of their final stage, which is dangerous for human life due to its complications.

Keefektivan Pembelajaran Secara Online Terhadap Perkembangan Fisik Motorik Anak

The problem in this research is that in the online learning process the teachercannot monitor the physical development of the child's motor skills, because children studyat home and at home, the children cannot freely leave the house to play or go recreation.As a result, many parents think that playing cellphones is the main solution. The purposeof this study was to determine the effectiveness of online learning on motoric physicaldevelopment. The benefits of this research are expected to provide insight, boththeoretically and practically, for researchers in accordance with the focus of the researchbeing carried out. This research is a descriptive study, while the research information is asource of reference as well as previous research. Data collection was carried out by meansof observation, interview and documentation techniques. The instrument used by theresearcher was a physical motor indicator. Data analysts use an interactive analysis modelby collecting data, reducing data, presenting data, and drawing conclusions. The results ofresearch on children's physical motor development during online learning have decreased.

Graphic design as a means of advertising transmission ideas in polygraphy

The purpose of the article is a substantiation of the use of visual images in the form of graphic models in printing advertising, consideration of the basic categories of graphic design in advertising, generalization of theoretical approaches to understanding the essence and content of the visual design of the advertising product. Methodology: analysis, synthesis, generalization. The research methodology consists in the application of general and special methods of cognition, in particular, the author used comparative analysis, synthesis and generalization, terminological, chronological and other research methods, among which a special place is occupied by review-analytical monitoring of publications. The scientific novelty lies in the substantiation of the introduction of the visual image of the text in the layout of the advertising project as a necessary addition to the traditional use of graphics, taking into account the peculiarities of the advertising communication process. This provided an opportunity to generalize and specify the specifics of the development of advertising ideas in printing through graphic design. Conclusions: As a result of the study it was found that the basis of graphic design in advertising is the application in practice of interdisciplinary knowledge and skills, the specifics of figurative expression in the artistic sense of the word. It was also found that the use of means of visualization of verbal and nonverbal information in the creative advertising concept is a very important component when considering the design function as a means of transmitting advertising information in printing. Derivatives that underlie the disclosure of creative advertising ideas with the help of design tools have been identified. Key words: graphic design, visual communication, modeling, advertising, printing, information, visual, images, design, idea, research, information, technique, means, transfer, design, drawing, technique, environment, synthetic, landscape, style, direction, transformation.

PET PRODUCTS: RANGE AND CLASSIFICATION CRITERIA

Background. The market of goods for pets in Ukraine is promising and is characterized by rapid growth.The pet goods assortment is very wide and includes different subgroups. However, there is no works on the classification of the assortment of pet goods, except for food for them. The aim of the article is developing a classification of pet goods on base of the analysis of assortment. Materials and methods. General scientific methods of cognition: analysis, comparison and generalization were used during the research. Information base of the research: the range of products for animals presented in online stores. Results. According to the results of the analysis of the range of goods for animals in specialized and universal online stores, 9 types of goods for the transportation of pets have been identified.Goods for the transportation of pets can be classified according to the method of transportation and type of transport, type of goods, material from which it is made, size of the product, design features and other characteristics. The main classification features of goods for the arrangement of places of pet residence were determined: the type of goods, the type of animals for which it is intended, the material from which the product is made, the size. Additional classification features include design, equipment, the possibility of transformation, the presence of additional functions. The main classification features of goods for pet food were defined: purpose, type of animals, the material from which the product is made, type of product, size. Toilets fillers for pets can be classified by type of animals, type (material) of filler, functions (principle of action) of filler, size of fractions, the presence of flavor. The assortment of tools for dog and cat grooming includes different devices and acessories, which can be classified according to different characteristics depending on the type of product. The goods related to ammunition for dogs and cats can be classified by type of product, breed and/or size of the animal, the material from which the products are made, size, and other characteristics depending on the features of the type of product. Conclusion. The classification of goods for transportation, arrangement of accommodation and food, ammunition and toys for pets, which were developed in the work, indicates that their assortment is complex and can be classified on at least 5 signs.

Towards a Semantic Interoperable Flemish Research Information Space: Development and Implementation of a Flemish Application Profile for Research Datasets

In Flanders, Research Performing Organizations (RPO) are required to provide information on publicly financed research to the Flemish Research Information Space (FRIS), a current research information system and research discovery platform hosted by the Flemish Department of Economics, Science and Innovation. FRIS currently discloses information onresearchers, research institutions, publications, and projects. Flemish decrees on Special and Industrial research funding, and the Flemish Open Science policy require RPOs to also provide metadata on research datasets to FRIS. To ensure accurate and uniform delivery of information across all information providing institutions on research datasets to FRIS, it isnecessary to develop a common application profile for research datasets. This article outlines the development of the Flemish application profile for research datasets that was developed by the Flemish Open Science Board (FOSB) WorkingGroup Metadata and Standardization. The main challenge was to achieve interoperability among stakeholders, which in part had existing metadata schemes and research information infrastructures in place, while others were still in the early stages of development.

Improving Data Transparency and Accessibility in the Research Community through the Construction of Accurately Simulated Time-to-Event Datasets

BackgroundA lack of availability of data and statistical code being published alongside journal articles provides a significant barrier to open scientific discourse, and reproducibility of research. Information governance restrictions inhibit the active dissemination of individual level data to accompany published manuscripts. Realistic, accurate time-to-event synthetic data can aid in the acceleration of methodological developments in survival analysis and beyond by enabling researchers to access and test published methods using data similar to that which they were developed on.MethodsThis paper presents methods to accurately replicate the covariate patterns and survival times found in real-world datasets using simulation techniques, without compromising individual patient identifiability. We model the joint covariate distribution of the original data using covariate specific sequential conditional regression models, then fit a complex flexible parametric survival model from which to simulate survival times conditional on individual covariate patterns. We recreate the administrative censoring mechanism using the last observed follow-up date information from the initial dataset. Metrics for evaluating the accuracy of the synthetic data, and the non-identifiability of individuals from the original dataset, are presented.ResultsWe successfully create a synthetic version of an example colon cancer dataset consisting of 9064 patients which aims to show good similarity to both covariate distributions and survival times from the original data, without containing any exact information from the original data, therefore allowing them to be published openly alongside research. ConclusionsWe evaluate the effectiveness of the simulation methods for constructing synthetic data, as well as providing evidence that it is almost impossible that a given patient from the original data could be identified from their individual unique date information. Simulated datasets using this methodology could be made available alongside published research without breaching data privacy protocols, and allow for data and code to be made available alongside methodological or applied manuscripts to greatly improve the transparency and accessibility of medical research.

Public Attitudes Towards Sharing Loyalty Card Data for Academic Health Research: a Qualitative Study

Background: A growing number of studies show the potential of loyalty card data for use in health research. However, research into public perceptions of using this data is limited. This study aimed to investigate public attitudes towards donating loyalty card data for academic health research, and the safeguards the public would want to see implemented. The way in which participant attitudes varied according to whether loyalty card data would be used for either cancer or COVID-19 research was also examined. Methods: Participants (N=40) were recruited via Prolific Academic to take part in semi-structured telephone interviews, with questions focused on data sharing related to either COVID-19 or ovarian/bowel cancer as the proposed health condition to be researched. Content analysis was used to identify sub-themes corresponding to the two a priori themes, attitudes and safeguards.Results: Participant attitudes were found to fall into two categories, either rational or emotional. Under rational, most participants were in favour of sharing loyalty card data. Support of health research was seen as an important reason to donate such data, with loyalty card logs being considered as already within the public domain. With increased understanding of research purpose, participants expressed higher willingness to donate data. Within the emotional category, participants shared fears about revealing location information and of third parties obtaining their data. With regards to safeguards, participants described the importance of anonymisation and the level of data detail; the control, convenience and choice they desired in sharing data; and the need for transparency and data security. The change in hypothetical purpose of the data sharing, from Covid-19 to cancer research, had no impact on participants’ decision to donate, although did affect their understanding of how loyalty card data could be used. Conclusions: Based on interviews with the public, this study contributes recommendations for those researchers and the wider policy community seeking to obtain loyalty card data for health research. Whilst participants were largely in favour of donating loyalty card data for academic health research, information, choice and appropriate safeguards are all exposed as prerequisites upon which decisions are made.