scholarly journals Melanotrichoblastoma: A Rare Case Report from B. P. Koirala Institute of Health Sciences, Dharan, Nepal

2017 ◽  
Vol 2 (1) ◽  
pp. 145-147
Author(s):  
Sairil Pokharel ◽  
S Karki ◽  
A Pradhan ◽  
S Agrawal
Keyword(s):  
S100 Protein ◽  
Malignant Lesion ◽  
Punch Biopsy ◽  
Health Sciences ◽  
Definitive Diagnosis ◽  
Temporal Region ◽  
Immunohistochemistry Analysis ◽  
Rare Case Report ◽  
The Right ◽  
Adnexal Tumors

Melanotrichoblastoma is a variant of pigmented trichoblastoma. It shows heavily pigmented epithelial lobules and differentiaion toward the hair bulb. Abundant dendritic melanocytes are found within the tumor masses. These melanocytes show positivity for S100 protein, HMG45/gp 100 and tyrosinase. The case is being reported because of its rarity.A twenty eight year lady presented to Dermatology OPD with a single nodular lesion on the right temporal region since last five years. Punch biopsy was done. Haematoxylin and eosin stained slides were studied and immunohistochemistry analysis was also done.Variably sized epithelial lobules of basaloid cells spanning the entire dermis was noted on H and E stained slides. Some lobules showed pale looking cells- a reminiscent of follicular germinative cells. Intralesional melanocytes with pigmentation were observed. Immunohistochemistry results showed the melanocytes positive for HMB-45 and S100 and the stroma positive for CD 34. Hence, a definitive diagnosis of Melanotrichoblastoma was made.This case is being presented to emphasize the difficulty posed by adnexal tumors in clinical diagnosis due to their clinical similarity with malignant lesion and rarity.Birat Journal of Health Sciences Vol.2/No.1/Issue 2/ Jan - April 2017

scholarly journals Blaschkoian Lichen Planus in an Amazghi; A Rare Case Report

2014 ◽  
Vol 8 (1) ◽  
pp. 45-50
Author(s):  
Ebtisam Elghblawi
Keyword(s):  
Lichen Planus ◽  
Previous History ◽  
Unknown Origin ◽  
Skin Lesions ◽  
Punch Biopsy ◽  
Late Presentation ◽  
Inflammatory Dermatosis ◽  
Rare Case Report ◽  
Lines Of Blaschko ◽  
The Right

Lichen planus (LP) is a common acquired inflammatory dermatosis of unknown origin with several morphological forms. Linear lichen planus is frequently seen but cases of zonal/ zosteriform/ dermatomal/ blaschkoid LP are rare. Typically LP is merely acknowledged as an old companion to a dermatologist in the clinic. Nonetheless sometimes it comes in masquerades. Many reports have documented LP to occur in scars of previous herpes zoster (HZ) lesions. Zosteriform LP without evidence of HZ is an extremely rare occurrence in the head and neck area. To the best of my knowledge such a condition has not been reported in the literature previously. I report a healthy 53-year old Amazaghi woman with grouped lichenoid, unilateral linear plaque skin lesion on the right side of the face that followed the lines of Blaschko with no previous history of HZ on the involved area. The punch biopsy specimen confirmed the typical histology of lichen planus. A clinical diagnosis was made based on the clinical picture and biopsy reading. Usually Blaschko linear skin lesions develop later in life with distinctive features, and thus it should be differentiated from other acquired skin dermatoses. I report this case of LP type for its scarcity and to add one more case to the list of existing literature, with the idiosyncrasy of late presentation onset.

The Invisible Evil Twin of an Adrenal Adenoma

2019 ◽  
Vol 4 (1) ◽  
pp. 58
Author(s):  
Aimi Fadilah Mohamad ◽  
Fatimah Zaherah Mohamed Shah ◽  
Nur Aisyah Zainordin ◽  
Ur 'Aini Eddy Warman ◽  
Nazimah Ab Mumin ◽  
...  
Keyword(s):  
Adrenal Glands ◽  
Adrenal Adenoma ◽  
Definitive Diagnosis ◽  
Dynamic Tests ◽  
Venous Sampling ◽  
Aldosterone Secretion ◽  
Aldosterone Level ◽  
Suppression Test ◽  
The Right ◽  
Secondary Causes

Primary aldosteronism (PA) causes a persistently elevated blood pressure (BP) due to excessive release of the hormone aldosterone from the adrenal glands. Classically, it is called Conn’s syndrome and is described as the triad of hypertension and hypokalemia with the presence of unilateral adrenal adenoma. It can be cured with surgical resection of the aldosterone-secreting adenoma leading to resolution of hypertension, hypokalemia and increased cardiovascular risk associated with hyperaldosteronism. We present a case of a man with previous ischemic heart disease (IHD) who presented with resistant hypertension. Investigations for secondary causes of hypertension revealed an elevated aldosterone level and saline suppression test confirmed the diagnosis of PA. Radiological examination revealed a left adrenal adenoma and a normal right adrenal gland. However, adrenal venous sampling showed lateralization of aldosterone secretion towards the right. He subsequently underwent a laparoscopic right adrenalectomy which improved his BP control promptly. This case highlights the importance of recognizing the need to investigate for secondary causes of hypertension. It also underscores the importance of dynamic tests, which may not be easily accessible to most clinicians but should pursue, to allow a definitive diagnosis and effective treatment.

scholarly journals Intrascrotal lipoblastoma in adulthood

2019 ◽  
Vol 12 (12) ◽  
pp. e231320
Author(s):  
Mário José Pereira-Lourenço ◽  
Duarte Vieira-Brito ◽  
João Pedro Peralta ◽  
Noémia Castelo-Branco
Keyword(s):  
Case Report ◽  
Magnetic Resonance ◽  
S100 Protein ◽  
Surgical Excision ◽  
Large Mass ◽  
Histological Diagnosis ◽  
Physical Exam ◽  
Nodular Lesion ◽  
Inferior Portion ◽  
The Right

This case report describes the case of a 37-year-old man that noticed an intrascrotal right mass with 1 month of evolution. During physical exam presented with a large mass at the inferior portion of the right testicle, clearly separated from the testicle, with a tender consistency and mobile. An ultrasound was performed that showed a solid and subcutaneous nodular lesion, extra testicular, heterogeneous, measuring 7.2 cm. Pelvic magnetic resonance imageMRI showed a lesion compatible with a lipoma. The patient was subjected to surgical excision of the lesion by scrotal access, having histology revealed a lipoblastoma (LB) of the scrotum. Histological diagnosis was obtained by microscopic characteristics (well-circumscribed fatty neoplasm) and immunohistochemistry (stains for CD34, S100 protein and PLAG1 were positive; stains for MDM2 and CDK4 were negative). LB is extremely rare after adolescence in any location, being this first described case of intrascrotal LB described in adulthood.

scholarly journals A Rare Case Report of Unusual Path of Left Internal Jugular Central Line

2021 ◽  
pp. 1-3
Author(s):  
Rajashekar Rangappa Mudaraddi ◽  
Hany Fawzi Greiss ◽  
Navin Kumar Manickam
Keyword(s):  
Superior Vena Cava ◽  
Case Reports ◽  
Superior Vena ◽  
Vena Cava ◽  
Central Line ◽  
Left Superior Vena Cava ◽  
Common Procedure ◽  
Rare Case Report ◽  
The Right ◽  
Line Path

Central venous cannulation is the most common procedure performed in perioperative setting and intensive care unit. Many case reports reported unusual positioning of central line catheters. Here, we would like to report a case of central line path in persistent left superior vena cava, a rare entity with a course similar to the right internal jugular central line. Preoperative computed tomography chest showed duplex superior vena cava which was not reported.

scholarly journals Intraorbital wooden foreign body detected by computed tomography and magnetic resonance imaging

2016 ◽  
Vol 30 (1) ◽  
pp. 88-91 ◽  
Author(s):  
Alfredo Di Gaeta ◽  
Francesco Giurazza ◽  
Eugenio Capobianco ◽  
Alvaro Diano ◽  
Mario Muto
Keyword(s):  
Computed Tomography ◽  
Foreign Body ◽  
Magnetic Resonance ◽  
Delayed Diagnosis ◽  
Clinical History ◽  
Definitive Diagnosis ◽  
Double Vision ◽  
Resonance Imaging ◽  
Wooden Foreign Body ◽  
The Right

To identify and localize an intraorbital wooden foreign body is often a challenging radiological issue; delayed diagnosis can lead to serious adverse complications. Preliminary radiographic interpretations are often integrated with computed tomography and magnetic resonance, which play a crucial role in reaching the correct definitive diagnosis. We report on a 40 years old male complaining of pain in the right orbit referred to our hospital for evaluation of eyeball pain and double vision with an unclear clinical history. Computed tomography and magnetic resonance scans supposed the presence of an abscess caused by a foreign intraorbital body, confirmed by surgical findings.

scholarly journals LGG-05. MOLECULAR GUIDED THERAPY FOR A PEDIATRIC LOW GRADE GLIOMA: A CASE REPORT

2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii367-iii367
Author(s):  
Jayne VonBergen ◽  
Beth Armstrong ◽  
Morgan Schmitt
Keyword(s):  
Targeted Therapy ◽  
Standard Treatment ◽  
Head Tilt ◽  
Study Patient ◽  
Low Grade ◽  
Temporal Region ◽  
Low Grade Gliomas ◽  
Leptomeningeal Involvement ◽  
The Right ◽  
Guided Therapy

Abstract Low grade gliomas are the most common type of central nervous system tumors among children. Despite the fact that they are not typically life threatening, low grade gliomas remain a significant clinical challenge. Case Study: Patient is a 4-year-old male who presented at 20 months of age with several weeks of ataxia, emesis, and head tilt. Imaging revealed a right temporal lobe lesion; he was subsequently taken to surgery, where a gross total resection was achieved. Imaging 9 months post resection revealed recurrent disease within the right temporal region with leptomeningeal involvement. Four months later imaging revealed progression of multifocal disease and new growth within the sella. At this time the patient started standard treatment, Carboplatin and Vincristine, per CCG 9952A. Persistent slow progression was observed despite receiving standard therapy. The patient developed a grade 3 reaction to carboplatin, worsening with each subsequent dose. At this time, he was referred to our Precision Genomics Neuro Oncology program for tumor molecular characterization. Somatic tumor testing revealed an ETV6-NTRK3 fusion, at which time standard treatment was stopped, and patient began targeted therapy, Larotrectinib. Imaging was preformed 2 months post start of targeted therapy and revealed interval decrease in size of previously enhancing nodular lesions; findings consistent with treatment response. Disease burden continues to decrease with therapy. This case illustrates a clear benefit of using molecular guided therapy in low grade gliomas.

scholarly journals Atypical Growth Pattern of an Intraparenchymal Meningioma

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Zhen Zeng ◽  
Tijiang Zhang ◽  
Yihua Zhou ◽  
Xiaoxi Chen
Keyword(s):  
Growth Pattern ◽  
Pineal Region ◽  
Pathological Examination ◽  
Intracranial Meningioma ◽  
Temporal Region ◽  
Right Cerebral Hemisphere ◽  
Dural Attachment ◽  
The Right ◽  
Chinese Male ◽  
Irregular Mass

Meningiomas are the most common primary nonneuroglial extra-axial neoplasms, which commonly present as spherical or oval masses with a dural attachment. Meningiomas without dural attachment are rare and, according to their locations, are classified into 5 varieties, including intraventricular, deep Sylvain fissure, pineal region, intraparenchymal, or subcortical meningiomas. To the best of our knowledge, intraparenchymal meningioma with cerebriform pattern has never been reported. In this paper, we report a 34-year-old Chinese male patient who presented with paroxysmal headaches and progressive loss of vision for 10 months and blindness for 2 weeks. A thorough physical examination revealed loss of bilateral direct and indirect light reflex. No other relevant medical history and neurologic deficits were noted. Computed tomography and magnetic resonance imaging scans showed an irregular mass with a unique cerebriform pattern and extensive peritumoral edema in the parietal-occipital-temporal region of the right cerebral hemisphere. The initial diagnosis was lymphoma. Intraoperatively, the tumor was completely buried in a sulcus in the parietal-occipital-temporal region without connecting to the dura. The histological diagnosis was intracranial meningioma based on pathological examination. Therefore, when an unusual cerebriform growth pattern of a tumor is encountered, an intraparenchymal meningioma should be considered as a differential diagnosis.

scholarly journals Pyogenic granuloma of tongue: A rare case report

2014 ◽  
Vol 6 (3) ◽  
pp. 84-86
Author(s):  
Sonam Sharma ◽  
Amita Sharma ◽  
Ashok Kumar ◽  
Shivani Kalhan ◽  
Jasmine Kaur
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Male Patient ◽  
Rare Case ◽  
Pyogenic Granuloma ◽  
Definitive Diagnosis ◽  
Medical Sciences ◽  
New Approaches ◽  
Rare Case Report ◽  
Chronic Irritation

Pyogenic granuloma (PG) is a kind of inflammatory hyperplasia in response to chronic irritation. Here, we report a case of 64 year old male patient with PG on midline of the dorsum of the posterior third of the tongue. Its differential diagnosis, the importance of biopsy findings in establishing definitive diagnosis and about the new approaches for its treatment is discussed. DOI: http://dx.doi.org/10.3126/ajms.v6i3.10619Asian Journal of Medical Sciences Vol.6(3) 2015 84-86

scholarly journals Estimation of activity of administered 18F-fluorodeoxyglucose by measurement of the dose equivalent rate on the right temporal region of the head

2016 ◽  
Vol 3 (1) ◽  
Author(s):  
Kenta Sakaguchi ◽  
Makoto Hosono ◽  
Tomomi Imamura ◽  
Naomi Takahara ◽  
Misa Hayashi ◽  
...  
Keyword(s):  
Temporal Region ◽  
Dose Equivalent ◽  
18F Fluorodeoxyglucose ◽  
Equivalent Rate ◽  
The Right

scholarly journals Lupus vulgaris mimicking cutaneous leishmaniasis: A case report

2022 ◽  
Vol 13 (1) ◽  
pp. 53-56
Author(s):  
Nouf Faihan Bin Rubaian ◽  
Haya Fahad Alzamami ◽  
Gadah Abdulatif Alhosawi ◽  
Leena Abdulrahman Almuhaish
Keyword(s):  
Delayed Diagnosis ◽  
Punch Biopsy ◽  
Lupus Vulgaris ◽  
Cutaneous Tuberculosis ◽  
Dorsal Aspect ◽  
Skin Punch Biopsy ◽  
Diagnostic Difficulties ◽  
Anti Tubercular Therapy ◽  
The Right ◽  
Saudi Male

Lupus vulgaris (LV) is a progressive, chronic form of cutaneous tuberculosis (CTB). The head and neck regions are the most commonly affected sites, followed by the arms and legs. Occurring in unusual sites may pose diagnostic difficulties. Herein, we report a case of LV present on the dorsal aspect of the right hand in a twenty-year-old Saudi male. It was misdiagnosed as leishmaniasis as the patient lived in an area in which it was endemic, and was treated accordingly with no benefit. A skin punch biopsy was taken and the diagnosis of LV was confirmed. The lesion responded well to anti-tubercular therapy (ATT), yet healed with atrophic scarring. Although rare, clinicians must be aware of the importance of considering CTB as an important differential, as misdiagnosis or delayed diagnosis of this entity may eventually cause prolonged morbidity.

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