Quality of life and pain prevalence in postoperative patients with oral malignancy- a prospective longitudinal study

Background: Epidemiology of pain in oral cancer patients, the effects of curative treatment on this pain, and the impact that the pain experience may have on the patient.s quality of life is an overshadowed topic. Methods: A prospective and descriptive study on prevalence of pain, with its impact on quality of life (QOL) was carried out in 36 diagnosed cases of squamous cell carcinoma (SCC) of oral cavity, and were treated with a curative intension. QOL assessment was done using a questionnaire followed by clinical examination at 6months and 12 months post-treatment. Pain was assessed using memorial pain assessment card and pain faces. Results: 42 patients enrolled for this descriptive study but at the end of one year study period only 36 patients completed both the questionnaires. We observed that QOL in our patients, was significantly influenced by mode of soft tissue reconstruction, tongue mobility, speech intelligibility, cosmesis and oral competence. At 6months 16.7% patients reported no pain but at 12months this proportion increased to 52.8%. Severity of pain reduced significantly over time with significant improved pain relief. We observed significant correlation between pain, QOL and mood scale at 12months post-treatment. Conclusion: This study has clarified and statistically confirmed some principles on the residual QOL for patients treated by surgical resection and flap reconstruction for cancer of the oral cavity already presented in the literature. Pain is common among those presenting with curable head and neck cancer. Pain can be reduced by curative treatment. Health Renaissance, January-April 2013; Vol. 11 No.1; 125-133 DOI: http://dx.doi.org/10.3126/hren.v11i2.8219

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A Prospective longitudinal study comparing the impact of external radiation therapy with radical prostatectomy on health related quality of life (HRQOL) in prostate cancer patients

The Prostate ◽

10.1002/pros.10342 ◽

2004 ◽

Vol 58 (4) ◽

pp. 354-365 ◽

Cited By ~ 21

Author(s):

G. van Andel ◽

A.P. Visser ◽

A.H. Zwinderman ◽

M.C.C.M. Hulshof ◽

S. Horenblas ◽

...

Keyword(s):

Quality Of Life ◽

External Radiation ◽

Health Related Quality ◽

Prospective Longitudinal Study ◽

Related Quality ◽

Health Related ◽

External Radiation Therapy ◽

Prospective Longitudinal ◽

The Impact

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The impact of radiodermatitis in quality of life of patients with breast cancer during treatment: a prospective longitudinal study

Mastology ◽

10.29289/259453942018v28s1030 ◽

2018 ◽

Vol 28 (s1) ◽

pp. 29-29

Author(s):

Marceila A. Fuzissaki ◽

◽

Carlos E. Paiva ◽

Marco A. Oliveira ◽

Mariana T. M. Lima ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Longitudinal Study ◽

Prospective Longitudinal Study ◽

Prospective Longitudinal ◽

The Impact

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The Transplant Evaluation Rating Scale Predicts Clinical Outcomes 1 Year After Lung Transplantation: A Prospective Longitudinal Study

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.704319 ◽

2021 ◽

Vol 12 ◽

Author(s):

Mariel Nöhre ◽

Martina de Zwaan ◽

Maximilian Bauer-Hohmann ◽

Fabio Ius ◽

Christina Valtin ◽

...

Keyword(s):

Quality Of Life ◽

Lung Transplantation ◽

Clinical Outcomes ◽

Rating Scale ◽

Prospective Longitudinal Study ◽

Emotional Sensitivity ◽

Transplant Evaluation ◽

Prospective Longitudinal ◽

The Impact

Objectives: It has been recommended that all candidates for lung transplantation undergo pre-transplant psychosocial evaluation for risk assessment. However, psychosocial issues are only important if they correlate with outcomes after transplantation.Methods: In this prospective study patients who were referred for lung transplantation from 2016 to 2018 (n = 352) at Hannover Medical School were evaluated using the Transplant Evaluation Rating Scale (TERS). Clinical outcomes included listing, and post-transplant outcomes including mortality, medical aspects such as lung allograft dysfunction, hospitalizations, and renal function, behavioral aspects such as BMI and adherence, and mental issues such as levels of depression, anxiety, and quality of life. TERS scores were divided into tertiles and, in addition, the impact of the two subscale scores—“defiance” and “emotional sensitivity”—was investigated.Results: Of the patients who were transplanted (n = 271) and were still alive (n = 251), 240 had already reached their 1-year assessment at the end of 2020 and were evaluated 1 year after the operation. A subgroup of 143 received an extended mental assessment. BMI, adherence scores, levels of anxiety, depression, and quality of life 1 year post-transplantation differed significantly between TERS tertiles with higher TERS scores predicting less favorable outcomes. The TERS subscale “defiance” was predictive of BMI and adherence whereas the TERS subscale “emotional sensitivity” was predictive of symptoms of anxiety and depression, and quality of life 1 year after transplantation. Patients in the lowest TERS tertile were more likely to having been listed and—as a trend—to having survived the first year after transplantationConclusions: Our findings show that psychosocial factors as measured by TERS score are predictors of behavioral and mental outcomes 1 year after lung transplantation. The TERS allows us to focus on psychosocial risk factors that can be treated or minimized before or after transplantation.

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Study of Chemotherapy-Induced Cognitive Impairment in Women with Breast Cancer

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17238896 ◽

2020 ◽

Vol 17 (23) ◽

pp. 8896

Author(s):

Blanca Rodríguez Martín ◽

Eduardo José Fernández Rodríguez ◽

María Isabel Rihuete Galve ◽

Juan Jesús Cruz Hernández

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cognitive Impairment ◽

Cognitive Performance ◽

Anxiety And Depression ◽

Oncology Patients ◽

Prospective Longitudinal Study ◽

Prospective Longitudinal ◽

The Impact

Background: Oncology patients experience a large number of symptoms and, those referring to cognitive performance has an ever-increasing importance in clinical practice, due to the increase in survival rates and interest in the patient’s quality of life. The studies reviewed showed that chemotherapy-related cognitive impairment might occur in 15 and 50% of oncology patients. The main objective of this research was to study the impact of chemotherapy on the cognitive function of patients with locoregional breast cancer. Method: Analytical, prospective, longitudinal study using three measures, unifactorial intrasubject design, non-probability, and random selection sampling. The sample comprised women newly diagnosed with locoregional breast cancer in stages I, II, IIIA who received chemotherapy at the University Hospital of Salamanca (Complejo Asistencial Universitario de Salamanca), randomly selected for three years. Semi-structured interviews were conducted, and anxiety and depression (Hospital Anxiety and Depression scale, HAD); quality of life (QLQ-BR23 scale) and the following cognitive variables were assessed—processing speed, attention, memory, and executive functions (subtests of the Wechsler Intelligence Scale and the Trail Making Test). Results: The final sample size included 151 participants; 23 were excluded. A decline in cognitive performance was observed in patients, which did not completely recover two months after chemotherapy was completed. Additionally, worse cognitive performance was observed in patients with anxious or depressive symptoms. There was a negative impact on the quality of life. Conclusion: Chemotherapy had an impact on the cognitive performance of oncology patients in most cognitive domains studied.

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