scholarly journals Chronic Calcific Pancreatitis Associated Diabetes Presenting as Involuntary Weight Loss and Multiple Soft Tissue Calcifications in a Young Male

2018 ◽  
Vol 2 (2) ◽  
pp. 52-55
Author(s):  
Ravi Kant ◽  
Aditya Sudan

Introduction: Chronic Calcific Pancreatitis, a rare form of secondary diabetes occurs due to recurrent alcohol induced acute pancreatitis. Case Summary: A 28 year old male patient presented with significant involuntary weight loss associat-ed with a history of passing clay colored sticky stools for the past 1 year. He was also detected to have deranged blood sugars on routine work up at a local hospital for increased thirst and increased urine output. There was a history of recurrent bouts of moderate to severe abdominal pain over the past 3 to 4 years. At the time of initial presentation his Random blood sugar values was 468 mg/dL. Other routine tests tests were within normal limits. His serum amylase levels were 185 U/L and serum Lipase levels were 467 U/L. Conclusions: Chronic fibro calcific pancreatitis is a rare cause of diabetes in young patients but has a characteristic clinical picture with a young patient presenting with features of malabsorption and low BMI, low propensity for DKA , low beta cell reserve and sensitivity to Insulin. 

2017 ◽  
Vol 63 (4) ◽  
pp. 231-235
Author(s):  
Alexandr I. Tsiberkin ◽  
Tatiana L. Karonova ◽  
Anna B. Dalmatova ◽  
Elena N. Grineva

Prolactinomas are the most common of hormone secreting pituitary adenomas. Patients with prolactinomas generally have a benign prognosis. An algorithm is currently available for managing of this disease. Giant prolactinoma larger than 40 mm with severe invasive growth account for about 2—3% of the prolactin-secreting pituitary adenomas and evidence about management of such patients is limited. This case illustrates progress of a giant prolactin-secreting pituitary adenoma up to 70 mm in young male with a family history of prolactinomas in the absence of the adequate therapy for 8 years after initial diagnosis. After evaluation, it was decided to prescribe medical treatment. Cabergoline therapy started after evaluation appeared to be effective and had lead to significant decrease of serum prolactin level and shrinkage of pituitary adenoma. Described case emphasize the crucial role of identification of hyperprolactinemia among young patients on early stages of the disease. Our observation implies that treatment with dopamine agonists might be effective even in cases with giant prolactinomas.


2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Nagham Saeed Jafar ◽  
Warkaa Al Shamkhani ◽  
Sunil Roy Thottuvelil Narayanan ◽  
Anil Kumar Rajappan

Cardiac sarcoidosis is a major cause of death in patients with systemic sarcoidosis. Cardiac manifestations are seen in 2.3% of the patients. Atrioventricular (AV) block is one of the common manifestations of cardiac sarcoidosis. Other presentations of cardiac involvement include congestive heart failure, ventricular arrhythmias, and sudden cardiac death. The presence of AV block in young patients should raise the suspicion of sarcoidosis. AV block may be the only manifestation and patients may not have clinical evidence of pulmonary involvement. Here we describe a young male presented with exercise induced AV block rapidly progressing to complete heart block with recurrent syncope needing urgent pacemaker implantation. Factors that suggested an infiltrative process included his young age, rapidly progressive conduction abnormalities in the ECG in the absence of coronary disease, and previous history of cutaneous sarcoidosis.


2021 ◽  
Vol 8 (5) ◽  
pp. 1653
Author(s):  
Ashish Arsia ◽  
Priya Hazrah ◽  
Shabab Anwar ◽  
Shaji Thomas ◽  
Pooja Abbey ◽  
...  

Primary nodal gastrinoma is a rare entity and the diagnosis is often contemplative when no other non - nodal primary site can be identified despite thorough investigations and operative exploration. Here we report one such case wherein a primary nodal gastrinoma was diagnosed as an entity of exclusion. Additionally, the location of the disease outside the confines of the conventional gastrinoma triangle further contributes to the rarity of the presentation. A young male patient had presented to us with history of multiple operations in the past for recurrent upper abdominal pain presumably consequential to peptic ulcer disease viz a trucal vagotomy and gastrojejunostomy, duodenal ulcer perforation surgery and a cholecystectomy. CT scan and endoscopic USG showed a preaortic calcified node located outside the limits of the gastrinoma triangle. A raised serum gastrin level and an endoscopic guided FNAC confirmed the diagnosis of a gastrinoma. A 68 Ga-DOTANOC PET CT revealed an exclusive nodal uptake with no discenable primary lesion. Normalization of gastrin levels after removal of the involved pre-aortic node further pointed to the diagnosis of primary nodal gastrinoma. A high index of clinical suspicion is warranted especially in a history of multiple surgeries for recurrent upper abdominal pain and location of the lesion outside the confines of the ‘Gastrinoma Triangle’ should not be deterrent for the diagnosis.


2017 ◽  
Vol 03 (01) ◽  
pp. 084-086
Author(s):  
Mukesh Sharma ◽  
Purnima Thakur ◽  
Vikas Fotedar ◽  
Anjna Sharma ◽  
Debajyoti Chatterjee

AbstractWe report a case of intracranial hemangiopericytoma of a young male of 22 years who presented with neurological signs of impaired memory, left hemiparesis, headache, and two episodes of focal seizures. A significant history of head trauma 9 years back was given. A space-occupying lesion was identified in the bilateral frontoparietal region. The surgical intervention involved bilateral frontoparietal craniotomy and Simpson Grade II excision of tumor. Postoperative conformal radiotherapy was administered. A marked neurological improvement was subsequently observed. Peak incidence of this disease is in the fourth or fifth decade. However, our case is an exception presenting at an age of 22 years. Associated history of head trauma has only been infrequently reported in the past.


2020 ◽  
Vol 8 ◽  
pp. 2050313X2091092
Author(s):  
Anne DD Joseph ◽  
Thirunavukarasu Kumanan ◽  
Naarani Aravinthan ◽  
Navaneethakrishnan Suganthan

Remitting seronegative symmetrical synovitis with pitting edema is a rare but well-recognized clinical entity that is easily overlooked due to lack of clinical vigilance. It is classically described as an acute onset of symmetrical tenosynovitis of both upper and lower extremities with pitting edema, mostly noted in elderly population. Young patients with other rheumatological diseases and unilateral involvement had also been reported, but symmetrical remitting seronegative symmetrical synovitis with pitting edema in a young patient is a rare observation. We hereby report a case of a remitting seronegative symmetrical synovitis with pitting edema in a young male affected by no rheumatological diseases in the past, typically fulfilling the diagnostic criteria and well responded to low-dose steroid therapy. The salient features of the present case in terms of age, remitting seronegative symmetrical synovitis with pitting edema possibly related to undifferentiated arthropathy, reactive arthritis, or diabetes mellitus.


2016 ◽  
Vol 9 (1) ◽  
pp. 44
Author(s):  
Md. Abdul Aziz ◽  
Fatema Ahmed ◽  
Shafiqul Islam ◽  
Md. Sirajul Lslam ◽  
Rafiquzzaman Khan ◽  
...  

Autoantibody mediated acquired haomophilia is a rare disease. Hereditary haemophilia usually presents with traumatic or spontaneous bleeding in a young male with positive family history in maternal side.In this case study we described an elderly male patient presenting with short history of recurrent ecchymosis with no similar history in the past and no family history of similar illness. He ultimately turned out to be a case of acquired haemophilia due to SLE.


2021 ◽  
Vol 2 (3) ◽  
pp. 31-34
Author(s):  
Ratna Pancasari ◽  
Cholid Tri Tjahjono ◽  
Anna Fuji Rahimah ◽  
Indra Prasetya

Background: In young males, an acute myocardial infarction is an uncommon event. Thrombolism caused by nephrotic syndrome (NS) is one of the pathophysiologies of their infarctions. Case Illustration: A-24-y.o male patient, presenting with prolong typical chest pain since 72 hours before admission. The chest leads on an electrocardiogram (ECG) indicated ST-Elevation. Cardiac troponin was significantly raised. Since the previous two weeks, he has been experiencing nephrotic syndrome symptoms including anasarca edema.It was supported by laboratory data which is obtained proteinuria, hyperlipidemia and hypoalbuminemia. A complete acute occlusion of the proximal portion of the left anterior descending artery was revealed by coronary angiography. Increased fibrinogen levels appeared to be a contributing factor for hypercoagulable state in this patient, implying a correlation between coronary thrombosis and nephrotic syndrome. Discussion: Myocardial infarction (MI) is rare in young males, but it occurs 8 times more often in patients with NS than in the general population. Clinicians should pay closer attention to the history of previous diseases with a high risk of thromboembolism in young patients with MI, and they should specifically promote thromboembolism prevention and care in patients with renal disease to decrease the incidence of thromboembolism complications. Conclusion: Nephrotic syndrome should be considered as a contributing factor in any patient presenting with acute STEMI, particularly in young males.


2014 ◽  
Vol 21 (2) ◽  
pp. 239-244

Abstract The chronic subdural hematoma is a common pathology in elderly patients. There is usually a history of head trauma. The diagnosis of chronic subdural hematomas in young patients is very rare and few cases have been reported in the literature. The authors present a case of a patient of 16 years old who presented headache of two months of evolution, which was conducted by tomography diagnosis of chronic subdural hematoma. The patient had no history of mild trauma. Surgical management was performed, showing a satisfactory evolution.


2017 ◽  
Vol 20 (1) ◽  
pp. 35-37
Author(s):  
Anamika Jha

Tuberculosis is endemic in our part of the world and may have uncommon presentations like pancreatic involvement. A young male presented to the OPD with recent history of pain in epigastric region and was subsequently diagnosed with a multi-loculated cystic neoplasm in pancreatic head region on ultrasonography and CT scan. The pancreatic origin was confirmed on surgery while the histopathological study revealed tuberculous nature. This case report highlights the importance of considering tuberculosis in the differential diagnosis in pancreatic masses, especially, with atypical appearances, in young patients or with background predisposing to TB and the need for histological diagnosis.  


2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Sandrine Péneau ◽  
Kelly Virecoulon-Giudici ◽  
Julia Baudry ◽  
Caroline Méjean ◽  
Denis Lairon ◽  
...  

AbstractOrganic food consumption has risen in many countries during the past decades, but individual behaviors leading to these choices remain unclear.. The aim of this study was to evaluate the associations between cognitive restraint, weight loss diet history and organic food intake, in French adults. This cross-sectional analysis included 21,516 participants from the NutriNet-Santé cohort (26.4% male, mean age 55.3 years; SD = 13.8). Cognitive restraint was evaluated by the Three-Factor Eating Questionnaire and practice of weight-loss diet in the past years was assessed by an ad hoc questionnaire. Organic food intake of 17 food groups was assessed by the Organic-Food Frequency Questionnaire. Adjusted means of proportions of organic food intakes out of total food intakes were compared across quartiles of the cognitive restraint score and weight loss diet history. Analyses were adjusted for sociodemographic and lifestyle factors. Women with higher levels of cognitive restraint had in average a lower contribution of organic foods in their diet (26.5% in Q4 vs. 30.9% in Q1; p < 0.0001). In addition, women with a history of weight loss diet had in average a lower contribution of organic foods in their diet (27.1% in current/past vs. 28.5% in never dieters; p = 0.0012). Associations were observed in men for specific food groups. Overall, individuals, and in particular women, with higher cognitive restraint scores or with a history of weight loss diet consumed less organic food. Results suggest that it can be too complex to follow both weight control and organic food choice strategies at the same time.


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