Ischemic Stroke and its Association with Risk Factors at Nepalgunj Medical College  Teaching Hospital Kohalpur

Introduction: Incidence of stroke increases with age and growing elderly population worldwide, the number of patients with stroke are likely to increase. It is the third most common cause of death in world in that 85% are ischemic in nature. Atherosclerosis is a major risk factor in cerebrovascular diseases. Carotid Intima Media thickness (CIMT) is a surrogate marker of atherosclerosis and provides a non-invasive method for the risk assessment of cerebrovascular diseases. Aims: To study the atherosclerotic risk profile of patients admitted with ischemic stroke in medical ward with study of the carotid artery intima-media thickness in patients with acute ischemic stroke. Methods: 92 patients with ischemic strokes were studied in this observational study. Carotid Doppler was performed in all patients with emphasis on carotid artery stenosis and intima thickening. Analysis of Association of various risk factors was done in detail. Study period was from June 2019 to May 2020. Results: Higher degree of stenosis was associated with hypoechoic plaques and cortical strokes. Hypertension was the most common and most significant risk factor. Multiple risk factors also appear to have synergistic actions. Conclusion: Various modifiable risk factors provide valuable target for primary and secondary prevention of stroke. Carotid Doppler is a very cheap and highly effective tool for further management of stroke patients. Most of the asymptomatic patients, risk factors may warrant precautionary carotid Doppler, and may result in significant reduction in disease burden on the families and the community and should be encouraged.

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The Effects of an Intensive Lifestyle Modification Program on Carotid Artery Intima-Media Thickness: A Randomized Trial

American Journal of Health Promotion ◽

10.4278/0890-1171-21.6.510 ◽

2007 ◽

Vol 21 (6) ◽

pp. 510-516 ◽

Cited By ~ 19

Author(s):

Steven G. Aldana ◽

Roger Greenlaw ◽

Audrey Salberg ◽

Ray M. Merrill ◽

Ron Hager ◽

...

Keyword(s):

Risk Factors ◽

Heart Disease ◽

Cardiovascular Risk ◽

Carotid Artery ◽

Cardiac Rehabilitation ◽

Cardiovascular Risk Factors ◽

Dietary Habits ◽

Intima Media Thickness ◽

Media Thickness ◽

Number Of Patients

Purpose. This study evaluated the effect of the Dr. Dean Ornish Program for Reversing Heart Disease on cardiovascular disease as measured by the intima-media thickness of the common carotid artery and compared this effect to outcomes from patients participating in traditional cardiac rehabilitation. Design. Randomized clinical trial. Setting. SwedishAmerican Health System. Subjects. Ninety three patients with clinically confirmed coronary artery disease were randomly assigned to the intervention (n = 46) or traditional cardiac rehabilitation (n = 47). Intervention. Dr. Dean Ornish Program for Reversing Heart Disease. Measures. Ultrasound of the carotid artery and other cardiovascular risk factors were measured at baseline, 6, and 12 months. Analysis. Intent-to-treat analysis. Results. There was no significant reduction in the carotid intima-media thickness of the carotid artery in the Ornish group or the cardiac rehabilitation group. Ornish Program participants had significantly improved dietary habits (p < .001), weight (p < .001), and body mass index (p < .001) as compared with the rehabilitation group. The decrease in the number of patients with angina from baseline to 12 months was 44% in Ornish and 12% in cardiac rehabilitation. Conclusions. The Ornish Program appears to causes improvements in cardiovascular risk factors but does not appear to change the atherosclerotic process as it affects the carotid artery.

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Association between Carotid Artery Intima-Media Thickness and Stroke Risk Factors in Ischemic Stroke

Korean Journal of Stroke ◽

10.5853/kjs.2011.13.2.129 ◽

2011 ◽

Vol 13 (3) ◽

pp. 129

Author(s):

Kwangsoo Kim ◽

Ju Young Na

Keyword(s):

Risk Factors ◽

Ischemic Stroke ◽

Carotid Artery ◽

Stroke Risk ◽

Intima Media Thickness ◽

Stroke Risk Factors ◽

Media Thickness

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Carotid artery intima-media thickness in patients with acute ischemic stroke and its correlation with risk factors for atherosclerosis and/or stroke

Asian Journal of Medical Sciences ◽

10.3126/ajms.v6i1.10301 ◽

2014 ◽

Vol 6 (1) ◽

pp. 22-27

Author(s):

Shovan Kumar Das ◽

Amit Sarkar ◽

Subhraprakash Pramanik ◽

Mitabha Bandyopadhyay ◽

Koushik Mondal ◽

...

Keyword(s):

Risk Factors ◽

Ischemic Stroke ◽

Carotid Artery ◽

Acute Ischemic Stroke ◽

Intima Media Thickness ◽

Cross Sectional Study ◽

Cross Sectional ◽

Media Thickness ◽

Matched Study ◽

Atherosclerotic Risk Factors

Introduction: Stroke is the second leading cause of mortality worldwide. Ischemic stroke is more prevalent than hemorrhagic stroke and atherosclerosis is the major cause of ischemic stroke. The increased carotid artery intima-media thickness (CIMT) is considered to be useful indicator of early atherosclerosis. So, this study was aimed to correlate the relationship between atherosclerotic risk factors and intima-media thickness of carotid artery in patients with acute ischemic stroke. Material and Methods: In this cross-sectional study, 100 consecutive patients of acute ischemic stroke and 50 healthy relatives of patients as control were studied for presence of atherosclerotic risk factors and carotid artery intima?media thickness by B-mode Doppler ultrasonography.Results: In this age and sex matched study, higher CIMT measurement was found among patients of acute ischemic stroke than healthy controls (0.849 ± 0.196 vs 0.602 ± 0.092; p < 0.001). The CIMT was well correlated with smoking (Beta = 0.295; t = 5.728; 95% CI 0.088 to 0.181; p < 0.001); hypertension (Beta = 0.387; t = 6.518; CI 0.112 to 0.209; p < 0.001); di abetes (Beta = 0.237; t = 4.848; CI 0.074 to 0.175; p < 0.001); hypercholesterolemia (Beta = 0.292; t = 5.840; CI 0.096 to 0.195; p < 0.001), but not with age (p = 0.153). The CIMT was also found to be higher among acute ischemic stroke patients who were smoker, hypertensive, diabetic and hypercholesterolemic than non?smoker, normotensive, non-diabetic and normo-cholesterolemic respectively. Conclusion: The CIMT being indicator of atherosclerosis can be used as future predictor of ischemic stroke. DOI: http://dx.doi.org/10.3126/ajms.v6i1.10301 Asian Journal of Medical Sciences Vol.6(1) 2015 22-27

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CAROTID DOPPLER AS A BIOMARKER TO DETERMINE STENOSIS IN ISCHEMIC STROKE AND MANAGEMENT OF ICU PATIENT

International Journal of Advanced Research ◽

10.21474/ijar01/11865 ◽

2020 ◽

Vol 8 (10) ◽

pp. 375-380

Author(s):

Samia Perwaiz Khan ◽

◽

Sabeeh Jaffrey ◽

Safia Izhar ◽

Khwaja Zafar Ahmed ◽

...

Keyword(s):

Ischemic Stroke ◽

General Hospital ◽

Color Doppler ◽

Invasive Procedure ◽

Intima Media Thickness ◽

Cerebrovascular Diseases ◽

Consent Form ◽

Plaque Morphology ◽

Media Thickness ◽

Carotid Doppler

Atherosclerosis is common cause of cerebrovascular diseases. Carotid Doppler is tool to determine atherosclerotic risk in patients leading to stroke. Carotid sonography isa invasive procedure and is most commonly being used. Proper management of atherosclerotic plaque and thickness could be reducing morbidity and mortality.All those patients with stroke admitted to Medicare cardiac and general hospital will be included in the study. All those patients with stroke due to intracerebral hemorrhage will be excluded from the study .Consent form was filled by the relatives of patients. Carotid Doppler was carried out external, middle and internal carotid arteries. Performa and consent form was filled by patient/ attendant. Pre and post antiplatelet and antithrombotic therapy color Doppler was done.Out of a total of 25 patients with stroke admitted or attending the walk-in clinic of medicare cardiac 7 general hospital . Intima media thickness was increased in 25 (100%) above 0.1mm ,calcified plaques were found in 20 ( 90%) patients and stenosis was less than 40% in 19 patients and above 50% in 6 patients. Control shown to have normal intima media thickness 0.1-0.6 mm , no plaques or stenosis. Carotid Doppler is found to be most useful biomarker to determine stenosis in ischemic stroke and plaque morphology also to management of intensive care unit patient.

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