scholarly journals Clinical Profile, Bacterial Isolates and Antibiotic Susceptibility Patterns in Urinary Tract Infection in Children – Hospital Based Study

1970 ◽  
Vol 28 (2) ◽  
pp. 52-61 ◽  
Author(s):  
KK Malla ◽  
MS Sarma ◽  
T Malla ◽  
A Thapalial

Keywords: Urinary tract infection; culture and suseptibility patternsDOI = 10.3126/jnps.v28i2.1388J. Nepal Paediatr. Soc. Vol.28(2) 2008 p.52-61

Medicine ◽  
2017 ◽  
Vol 96 (37) ◽  
pp. e7834 ◽  
Author(s):  
Gholamreza Pouladfar ◽  
Mitra Basiratnia ◽  
Mojtaba Anvarinejad ◽  
Pejman Abbasi ◽  
Fatemeh Amirmoezi ◽  
...  

2021 ◽  
Vol 10 (4) ◽  
pp. 2820-2830

Recently, the world's problem has become in the spread of microbes and the extent of their impact on public health, especially the problem of urinary tract infections (UTIs). Therefore, the purpose of the study was to clarify the extent of infection of the urinary tract and the extent of development of these microbes in resistance to antibiotics (antibiotic susceptibility pattern). The pathogens are isolated from hospitals and private medical centers. In this study, two hundred twenty-five urine samples were collected from various sources, where 126 patients were infected with bacteria while 99 patients had no infection. In Gram-negative bacteria, the most common bacteria were E. coli (55.5%) followed by Klebsiella spp (23.0%), Proteus spp (7.14%), Pseudomonas spp (6.34%), and Acinetobacter spp (3.96%). In the Gram-positive bacteria Staphylococcus spp (2.38%) and Enterococcus spp (1.58%) were found. Antibiotic susceptibilities for Gram-negative and positive bacteria were investigated according to clinical laboratory standard institute(CLSI 2019). In Gram-negative bacteria, Amikcin, Impinem, and levofloxacin were sensitive. However, in Gram-positive bacteria, levofloxacin, ofloxacin, and linezolid were sensitive. At the same time, most of the remaining antibiotics are 100% resistant to pathogenic-bacterial isolates. This study showed bacteria that are isolated from urine which causing urinary tract infection and showed resistance to almost all antibiotics, so UTI is difficult to treat by common antibiotics.


2020 ◽  
Author(s):  
Gebremedhin Yenehun Worku ◽  
Yerega alamneh belete ◽  
Woldaregay Erku Abegaz

Abstract Background: Urinary tract infection (UTI) is caused by colonization and growth of microorganisms within the urinary system. Diabetic patients are more prone to bacterial urinary tract infections due to impaired host defense and high glucose concentration in urine. Surveillance of urinary tract pathogens and their antibiogram is a key to patient management. The aim of this study was to determine the prevalence of bacterial UTI and antimicrobial susceptibility patterns (AST) among diabetes patients. Methods: Hospital-based cross-sectional study was conducted from May to July, 2018. Two hundred twenty-five mid-stream urine samples were collected for culture and identification based on the standard protocol. Antimicrobial susceptibility test was done for all positive urine cultures by Kirby Bauer's disk diffusion method based on CLSI guidelines. Data were entered into Epi-data version 3.2.1 and exported to the Statistical Package for the Social Science (SPSS) version 20 statistical software. Binary and multiple logistic regression test results were used.Results: The study result revealed 9.8% overall UTI prevalence. Five species of bacterial uropathogens were isolated. Among these, E. coli (63.6%) was the leading followed by K. pneumoniae (13.6%). In this study, significant bacteriuria was strongly associated with duration of diabetics, previous UTI and symptomatic UTI. Gram-negative bacterial isolates showed high level of sensitivity (100%) to nitrofurantoin and meropenem. On the contrary, high level of resistance (100 %) for ampicillin, doxycycline, cefuroxime, and (94.4 %) amoxacillin-clavulanate were observed. No resistance was observed among gram positive bacterial isolates except penicillin (100 % resistance). Over all prevalence of MDR was 100 % For Gram-negative bacteria.Conclusion: Presence of previous urinary tract infection and duration of diabetes were found as important factors that increase the prevalence of UTI among diabetes patients. This study also showed high prevalence of drug resistance to doxycycline, amoxacillin-clavulanate, cefuroxime and penicillin for both Gram- negative and Gram- positive bacteria. Therefore, since therapeutic selection for empirical treatment and management should be based on the knowledge of the local bacterial profile and antimicrobial response, we suggest physicians take this high resistance profile in to consideration when prescribing antimicrobials against the pathogens in question.


Author(s):  
C. O. Aleke ◽  
K. O. Ugwu ◽  
O. N. Akoma ◽  
I. M. Ezeonu

Urinary Tract Infection (UTI) is one of the significant healthcare and hygienic-based diseases ravaging millions of people, especially in third world countries with poor hospital settings. This cross-sectional and laboratory investigation was done to determine the incidence of nosocomial urinary tract infections (NUTIs) and antibiotic susceptibility pattern of the uropathogenic bacterial isolates from hospital patients in Nsukka, Southeastern Nigeria. Urine specimens of fifty patients were collected and analyzed between May and June 2018. Kirby-Bauer disk diffusion method was used for detection of antibiotic susceptibility pattern for all isolates. Bacteriuria was observed in urine specimens of 31 (62%) out of the 50 participants, with the specimens of 13 yielding significant growth at 42% rate of nosocomial urinary tract infections (NUTIs). The most predominant bacterial isolate of urinary tract infection was Staphylococcus spp. (31%); followed by Escherichia, Klebsiella and Proteus with (23%) each. Isolates were mostly susceptible to Ciprofloxacin (87.1%), while other isolates were mainly resistant to Zinnacef (937%). Pertinent recommendations were made with respect to treatment, multidrug resistance mitigation and aseptic and optimal health services delivery practices.


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