scholarly journals Mucinous Carcinoma of the breast with micropapillary pattern and psammomatous calcification: A case study.

2021 ◽  
Vol 11 (1) ◽  
pp. 1886-1890
Author(s):  
Koushiki Bhattacharjee ◽  
Manna Valiathan
Keyword(s):  
Incidental Finding ◽  
Radical Mastectomy ◽  
Mucinous Carcinoma ◽  
Left Breast ◽  
Psammoma Bodies ◽  
Carcinoma Of The Breast ◽  
Outer Quadrant ◽  
Nulliparous Female ◽  
Micropapillary Pattern

Mucinous carcinoma with a micropapillary pattern is an unusual form of Invasive breast cancer exhibiting dual mucinous and micropapillary differentiation. The present case is of a 47-year-old nulliparous female who presented with an incidental finding of a hard lump in her left breast. Mammography revealed a BIRADS 4 lesion. Modified radical mastectomy was done and the specimen was grossed, revealing a tumor of 3x2.6x2.6 cm in the outer quadrant. Microscopy revealed the tumor having extracellular mucin pools with floating psammoma bodies and focal micropapillary pattern. Four of the twenty-six lymph nodes sampled were found to have tumor deposits. The micropapillary pattern was maintained in the metastatic deposits. Immunohistochemistry revealed ER and PR positivity and Her2Neu negativity. EMA corroborated the findings. It is important to recognize the micropapillary pattern in mucinous carcinomas of the breast as these tumors tend to be more aggressive than pure mucinous breast lesions. 

scholarly journals Pure Mucinous Breast Carcinoma with Micropapillary Pattern in a 32-Year-Old Female

2021 ◽  
pp. 338-341
Author(s):  
Nahid Sadeghi ◽  
Razieh Shahnazari ◽  
Fariba Asadi
Keyword(s):  
Varicose Veins ◽  
Brain Magnetic Resonance Imaging ◽  
Radical Mastectomy ◽  
Mucinous Carcinoma ◽  
Needle Aspiration ◽  
Left Breast ◽  
Good Prognosis ◽  
Case Presentation ◽  
The Face ◽  
Micropapillary Pattern

Background: Mucinous carcinoma (MC) is a rare breast malignancy with a large extracellular mucin secretion. It has a good prognosis in comparison to other breast malignancies.  Case presentation: We report a 32 years old female with multiple hard palpable masses in the left breast with rapid growth in 6 months. She was mentally retarded with lower limb varicose veins associated with mucocutaneous lesions on the face. She underwent ultrasound examination of the breast, thyroid and lower extremity veins. Core needle biopsy and fine needle aspiration from left breast lesions and right thyroid nodules showed MC and follicular lesion with hurtle cell change, respectively. Suspected metastasis in the left rib and calvarium in the subsequent bone scan survey and brain magnetic resonance imaging was reported. She underwent radical mastectomy and right hemi-thyroidectomy. Conclusion: Pure mucinous carcinoma with micropapillary pattern (MUMPC) is a new histology variant of Pure Mucinous Carcinoma (PMC) that shows favorable prognosis with less aggression and occurs in older patients. However, PMC in our patient occurred at a young age with greater aggression.

Adenoid Cystic Carcinoma of the Breast detected with Contrast-Enhanced Spectral Mammography: A Case Report

2020 ◽  
Vol 16 ◽  
Author(s):  
Yun-Chung Cheung ◽  
Shir-Hwa Ueng ◽  
Shu-Hang Ng ◽  
Wen-Lin Kuo
Keyword(s):  
Left Breast ◽  
Breast Cancers ◽  
Resonance Imaging ◽  
Carcinoma Of The Breast ◽  
Outer Quadrant ◽  
Additional Information ◽  
Adenoid Cystic ◽  
Modern Technique ◽  
Contrast Enhanced ◽  
Rim Enhancement

Background: Contrast-enhanced spectral mammogram (CESM) is a modern technique providing additional information to detect or diagnose the breast cancers. Introduction: We present a rare ACC of breast on CESM. Methods: A 49-year-old woman with surgicopathological proved ACC is reported with features on CESM, sonography and contrast-enhanced magnetic resonance imaging (CE-MRI). Results: Sonography revealed a 1.4 cm × 1.2 cm × 1 cm circumscribe round mass in the upper outer quadrant of the left breast that was diagnosed to fibroadenoma. The mammogram did not show any discernible mass, however the recombined subtracted images displayed a circumscribe mass with thin rim enhancement and enhanced internal patches that were resembling to CE-MRI. Finally, the mass was proved to ACC. Conclusion: CESM facilitates detection of an isodense cancer and provides the enhanced features for differential diagnosis. Resembling CE-MRI, CESM displayed rim enhancement and internal enhanced patches as diagnostic clues for this case of ACC.

scholarly journals Pure Mucinous Breast Carcinoma with Micropapillary Pattern (MUMPC): A Case Report

2019 ◽  
Vol 12 (2) ◽  
pp. 554-559
Author(s):  
Yuka Asano ◽  
Shinichiro Kashiwagi ◽  
Mizuki Nagamori ◽  
Sayaka Tanaka ◽  
Yuko Kuwae ◽  
...  
Keyword(s):  
Breast Carcinoma ◽  
Left Breast ◽  
World Health ◽  
Histopathological Diagnosis ◽  
Axillary Lymph ◽  
Invasive Micropapillary Carcinoma ◽  
Outer Quadrant ◽  
Atypical Cells ◽  
Micropapillary Pattern ◽  
Mucinous Breast Carcinoma

Pure mucinous breast carcinoma with micropapillary pattern (MUMPC) was proposed as a new histopathological variant of pure mucinous carcinoma (PMC) with tumor cells forming a micropapillary architecture. The Classification of Tumours of the Breast by the World Health Organization, however, does not differentiate MUMPC as a distinct subtype. There is currently no consensus whether tumors that exhibit these features are classified as PMC or invasive micropapillary carcinoma (IMPC) with associated mucin production. A 45-year-old woman was examined for a tumor in her left breast. Upon physical examination, an elastic hard mass of around 5 cm along with accompanying skin flare and ulceration was palpated in the upper outer quadrant of the left breast. Mammary ultrasonography revealed a clearly marginated hypoechoic tumor of 55.0 × 46.9 × 37.0 mm in size in the upper outer quadrant of the left breast. A vacuum-assisted biopsy (VAB) was performed in the same site and histopathological diagnosis of PMC was made. Contrast-enhanced magnetic resonance imaging (MRI) showed a T1W1 low-intensity signal and a T2W1 high-intensity signal at the primary focus, ring enhancement of the tumor margin, and stranding enhancement inside the tumor. A preoperative diagnosis of left breast cancer (PMC), cT4bN1M0, stage IIIB, luminal B-like was made. We performed a simple mastectomy with axillary lymph node dissection. A 55.0 × 48.1 × 37.1 mm tumor with the gelatinous cut surface was excised. Histopathological examination of the excised specimen revealed mucin lake formation in the tumor containing clusters of atypical cells. The atypical cells showed swollen, irregular nuclei and a papillary growth pattern that lead to the diagnosis of MUMPC.

Prognostic Significance of Micropapillary Pattern in Pure Mucinous Carcinoma of the Breast

2008 ◽  
Vol 16 (3) ◽  
pp. 251-256 ◽  
Author(s):  
Amanjit Bal ◽  
Kusum Joshi ◽  
Suresh Chander Sharma ◽  
Ashim Das ◽  
Alka Verma ◽  
...  
Keyword(s):  
Prognostic Significance ◽  
Mucinous Carcinoma ◽  
Carcinoma Of The Breast ◽  
Micropapillary Pattern

Micropapillary pattern in pure mucinous carcinoma of the breast - does it matter or not?

2018 ◽  
Vol 74 (2) ◽  
pp. 248-255 ◽  
Author(s):  
Xiaoli Xu ◽  
Rui Bi ◽  
Ruohong Shui ◽  
Baohua Yu ◽  
Yufan Cheng ◽  
...  
Keyword(s):  
Mucinous Carcinoma ◽  
Carcinoma Of The Breast ◽  
Micropapillary Pattern

scholarly journals Small Cell Neuroendocrine Carcinoma of the Breast: Report of a Case

2018 ◽  
Vol 2 (2) ◽  
pp. 98
Author(s):  
Ayse Parali ◽  
Afife Ozkal ◽  
Fulya Buse Gungor ◽  
Mukaddes Kubra Melemez ◽  
Betul Simsek ◽  
...  
Keyword(s):  
Neuroendocrine Tumor ◽  
Radical Mastectomy ◽  
Small Cell ◽  
Limited Information ◽  
Carcinoma Of The Breast ◽  
Small Cell Neuroendocrine Carcinoma ◽  
Outer Quadrant ◽  
The Right ◽  
Disease Free

Small cell neuroendocrine tumor of the breast is a rare clinical condition. Although there’s limited information about this entity, it is considered to have a poor prognosis. A 44-yearold woman presented with a 5 cm mass in the lower-outer quadrant of the right breast and its tru-cut biopsy results revealed a neuroendocrine tumor. She underwent a modified radical mastectomy followed by neoadjuvant chemotherapy and radiotherapy. She remains disease-free at the end of her 6-months follow-up period.International Journal of Human and Health Sciences Vol. 02 No. 02 April’18. Page : 98-101

scholarly journals Metastatic Carcinoma Breast Presenting as Appendicular Abscess

2021 ◽  
Author(s):  
Meenakshi Yeola (Pate) ◽  
Kushagra Singh ◽  
Darshana Tote ◽  
Azeem Javed Aalam ◽  
Pankaj Gharde
Keyword(s):  
Adjuvant Chemotherapy ◽  
Ductal Carcinoma ◽  
Incidental Finding ◽  
Iliac Fossa ◽  
Locally Advanced ◽  
Radical Mastectomy ◽  
Left Breast ◽  
Metastatic Carcinoma ◽  
Breast Lump ◽  
High Grade Fever

Breast cancer is the most common cancer in females worldwide and presents mostly as a hard painless lump in breast. Authors report a case of a 59-year-old female who presented to emergency department with complaints of pain and lump in right iliac fossa, high grade fever with chills and rigor, multiple episodes of vomiting. She was febrile having tachycardia with normal blood pressure. Examination revealed a firm tender lump in right iliac fossa with guarding of abdomen. Incidental finding of a large left sided breast lump was noted. Radiological investigations revealed appendicular abscess. She was undertaken for emergency diagnostic laparoscopy followed by appendectomy. Surprisingly, histopathology revealed deposits of ductal carcinoma in appendix. She developed faecal fistula at incision site. On further evaluation of left breast lump it was diagnosed as locally advanced breast carcinoma. Patient was managed with neo-adjuvant chemotherapy followed by left sided Modified Radical Mastectomy (MRM) and adjuvant chemotherapy. She was on regular follow-up since then. Appendicular metastasis is one of the rare sites of metastasis of breast malignancy and presentation as appendicular abscess made the diagnosis and management challenging.

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