scholarly journals Bacteriological profile and antibiotic sensitivity pattern in patients with Urinary tract infection

2017 ◽  
Vol 7 (1) ◽  
pp. 1066-1069 ◽  
Author(s):  
N Subedi ◽  
S Pudasaini
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Urine Culture ◽  
Antibiotic Sensitivity ◽  
Sensitivity Test ◽  
Age Group ◽  
E Coli ◽  
Bacteriological Profile ◽  
Culture And Sensitivity ◽  
Culture Positive

Background: Urinary tract infection is one of the common bacterial infections seeking treatment in clinical practice. A variety of organisms are associated with UTI and the most common organisms are Escherichia coli and other coliforms. Bacteriological investigations of UTI are not complete without antibiotic sensitivity test of the isolate. The aim of this study is to determine the bacteriological profile and antibiotic sensitivity patterns and their disease association.Materials and methods: This study was conducted in Shankarapur Hospital over a period of one year. All cases of suspected UTI sent for urine culture and sensitivity test were evaluated in this study. Disease associated with UTI, bacteriological profile and antibiotic sensitivity patterns were evaluated.Results: A total of 974 cases were sent for urine culture and sensitivity test. The total culture positive cases were 165 (17.4%).  The most common age group for culture positive test was 21- 30 years (33.3%) followed by 31- 40 years (25.5%). Female patients formed the majority of culture positive cases (84.8%) and E Coli (86.1%) was the most common organism isolated. Piperacillin- tazobactum and ceftriaxone were the most common antibiotic sensitive to the organisms. Simple uncomplicated UTI and PID were the most common indication for subjecting the patients to urine culture.Conclusion: UTI is most commonly seen in female of reproductive age group and the most common causative organism is E coli. Culture result and antibiogram helps the clinician for specific treatment of UTI.

scholarly journals A study on the bacteriological profile of urinary tract infection in adults and their antibiotic sensitivity pattern in a tertiary care hospital in central Kerala, India

2017 ◽  
Vol 5 (2) ◽  
pp. 666 ◽  
Author(s):  
Jubina Bency A. T. ◽  
Priyanka R. ◽  
Ponnu Jose
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Antimicrobial Agents ◽  
Urine Culture ◽  
Antibiotic Sensitivity ◽  
Positive Urine Culture ◽  
E Coli ◽  
Sensitivity Pattern ◽  
Positive Urine ◽  
Culture And Sensitivity

Background: Urinary tract infection is one of the most common bacterial infections in humans and a major cause of morbidity. The etiology of UTI and the antibiotic sensitivity pattern varies with the widespread availability of antimicrobial agents; UTI has become difficult to treat because of appearance of pathogens with increasing resistance to antimicrobial agents.Methods: A descriptive study done during January-June 2013. All positive urine culture and sensitivity reports of males and females aged 20-70years were included. A total of 373 positive urine culture cases were taken from the culture and sensitivity register from Microbiology department and details were entered using a questionnaire.Results: Out of 373 adults, males were 137 (36.7%) and females were 236 (63.3%). E. coli (74.3 %) was the most common organism, followed by Klebsiella (15.8%), Enterococcus, Pseudomonas and Staphylococcus. The incidence of UTI was more in patients in the age group of 60-70years. E. coli and Klebsiella were sensitive to Amikacin (97.1%), Nitrofurantoin (90.7%), Gentamycin and Imipenem. Both organisms were resistant to Ampicillin (>90%).Conclusions: In this study, females were mostly affected and the most common organisms were E.Coli and Klebsiella. These organisms were most sensitive to Amikacin, Nitrofurantoin and resistant predominantly to Ampicillin. The sensitivity and resistance pattern of uropathogens to common antimicrobial agents must be taken into account when selecting treatment plans for UTI.

scholarly journals Antibiotic sensitivity pattern in urinary tract infection among adults in central part of Nepal

2019 ◽  
Vol 9 (4) ◽  
pp. 18-23
Author(s):  
Arun Sedhain ◽  
Abja Sapkota ◽  
Bidhan Shrestha
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urine Culture ◽  
College Teaching ◽  
Sensitivity Test ◽  
E Coli ◽  
Common Organism ◽  
Sensitivity Pattern ◽  
Culture And Sensitivity

Background: Urinary tract infection (UTI) is characterized by pathological invasion of the urinary tract by microorganisms. Majorities of organisms causing UTI are gram negative bacteria, most common of which is E. coli. Urine culture and sensitivity test is used to isolate the organism and to identify the susceptible drug of choice for appropriate treatment. This hospital-based study was carried out to analyze the spectrum and antibiotic susceptibility of microorganisms causing UTI. Methods: A retrospective study was done to analyze the results of urine culture and sensitivity test done at Chitwan Medical College Teaching Hospital over a period of two and half years. Standard guideline and protocol were used to collect the urine sample and to perform the test. Data analysis was done using SPSS version 21.0. Result: Out of 12, 925 urine samples submitted for culture and sensitivity test during the study period, bacterial pathogens were isolated from 3, 173 (24.54%) samples, which was significantly higher among females (28%) than the males (17%). The most common organism isolated on the culture was E. coli (68.5%) followed by Klebsiella (18.4%). Sensitivity of the uropathogens was seen highest with colistin (79.2%) followed by teicoplanin (64.58%), Aztreonam (63.25%) and Ni­trofurantoin (61.16%). Most common antibiotics that showed resistance to the microorganisms in this study were Ampicillin (60.93%), Cotrimoxazole (53.72%), Cefixime (40.57%) and Levofloxacin (32.93%). Conclusions: This study has found a usual pattern of UTI with higher prevalence among females and E. coli being the most common organism. Nitrofurantoin has been found to have a good sus­ceptibility for the treatment of UTI.

scholarly journals Recent Antibiotic Sensitivity Pattern of Escherichia Coli in Urinary Tract Infection

2018 ◽  
Vol 30 (1) ◽  
pp. 61-65
Author(s):  
Md Abdul Bari ◽  
Mashiur Arefin ◽  
Moriom Nessa ◽  
Golam Mostofa ◽  
Tafiqul Islam
Keyword(s):  
Escherichia Coli ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urine Culture ◽  
Antibiotic Sensitivity ◽  
E Coli ◽  
Sensitivity Pattern ◽  
Marked Resistance ◽  
Culture Positive

The objective of the study is to assess the recent sensitivity pattern of Escherichia coli in Urinary tract infection (UTI). Widespread use of antibiotics has led to the emergence of resistant microorganisms. As the antibiotic sensitivity patterns of the microorganisms are frequently changing, this retrospective analysis was designed to assess the recent antibiotic sensitivity pattern of Escherichia coli (E. coli) in urinary tract infection among the human population. Details of 358 urine culture positive reports for E. coli and their antibiotic sensitivity pattern pertaining to the study period of 6 months from Jan 2017 to June 2017 were collected from Microbiology Laboratory of Diagnostic Centers at Rajshahi and the results were statistically analyzed. The antibiotics tested for sensitivity were amikacin, gentamycin, ciprofloxacin, levofloxacin, cotrimoxazole, nitrofurantoin, ceftazidime, ceftriaxone and cefixime. The sensitivity pattern of E.coli to antibiotics in UTI was amikacin (82.68 gentamycin (75.97%), nitrofurantoin (70.67), levofloxacin (44.13%), ceftazidime (42.17%), co-trimoxazole (40.78%), ceftriaxone (38.54%), ciprofloxacin (35.75%), and cefixime (24.02%). The study highlighted the marked resistance of E. coli to quinolones and third generation cephalosporins.TAJ 2017; 30(1): 61-65

scholarly journals Bacteriological Profile and Antibiogram of Uropathogens in Pediatric Age Group Population from a Tertiary Care Hospital in Western Nepal

2020 ◽  
Vol 8 (02) ◽  
pp. 51-56
Author(s):  
Subhash Lal Karn ◽  
Ravi Kumar Kushwaha ◽  
Sulochana Khatiwada ◽  
Shristi Raut Adhikari ◽  
Buddhi Raj Pokhrel ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urine Culture ◽  
Age Group ◽  
Pediatric Age ◽  
E Coli ◽  
Pediatric Age Group ◽  
Bacteriological Profile ◽  
Group Population

INTRODUCTION Urinary tract infection (UTI) is one of the most common bacterial infections encountered in day to day pediatrics practices. It has been a significant cause of acute morbidity and is also a significant cause of hospital attendance among children. In children, despite the presence of simple and reliable methods of preliminary screening of children's urine, UTI continues to be under-diagnosed. AIMS & OBJECTIVE The study aimed to know the clinical and bacteriological profile of urinary tract infection and to find out the drug resistance of bacterial isolates in pediatric age group population attending Universal College of Medical Sciences Teaching Hospital, Bhairahawa. MATERIALS & METHODOLOGY Three hundred and seven non-repetitive urine samples from UTI suspected pediatric patients were included in the study and subjected for microscopic urine analysis followed by semi- quantitative culture by calibrated loop method for estimation of significant bacteriuria. RESULTS Present study showed that UTIs are more common in girls (54.07%) than in boys (45.92%). In terms of urine culture, 98 (31.92%) subjects had positive urine culture. There was no consistent symptom common to all patients with UTI other than fever. E. coli was the commonest uropathogens isolated. E. coli was the principal isolates showing high susceptibility to Imipenem (90.5%).

scholarly journals Clinical, Epidemiological and Bacteriological Profile of Culture Positive Urinary Tract Infections in Febrile Children – A Cross Sectional Study

2021 ◽  
Vol 8 (10) ◽  
pp. 522-526
Author(s):  
Bhavani Shankar Rokkam ◽  
Chowdary Babu Menni ◽  
Ramu Pedada ◽  
Deepak Kumar Alikana
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Urine Culture ◽  
Signs And Symptoms ◽  
Cross Sectional ◽  
Bacteriological Profile ◽  
Tract Infections ◽  
Culture Positive

BACKGROUND Urinary tract infections (UTI) constitute a common cause of morbidity in infants and children. When associated with abnormalities of urinary tract, they may lead to long-term complications including renal scarring, loss of function and hypertension. Most urinary tract infections remain undiagnosed if investigations are not routinely performed to detect them. Prompt detection and treatment of urinary tract infections and any complicating factors are important. The objective of the study is to know the clinical, epidemiological and bacteriological profile (i.e. clinical signs and symptoms, age, sex, family history, associated urinary tract abnormalities, & causative organisms) of urinary tract infections in febrile children with culture positive urinary tract infection. METHODS This descriptive, cross sectional observational study was conducted at outpatient clinics of our “child health clinics” between May 2016 and April 2017 (one year). All children aged 0 to 12 years with culture positive urinary tract infections were included in this study to evaluate the clinical, epidemiological and bacteriological profile. RESULTS A total of 69 children with culture positive urinary tract infections were included in this study. Out of 69 children included in this study, 36 (52.2 %) were females and 33 (47.8 %) were males. Overall female preponderance was seen and the M: F ratio was 0.9:1. But during first year of life in our study group we had more boys (10, 14.49 %) affected with urinary tract infection than girls. 49.3 % of urinary tract infections in the present study belonged to lower socio-economic status. Most common organism causing urinary tract infection in our group was E. coli (56.5 %). Fever (100 %), anorexia or refusal of feeds (52.2 %), dysuria (46.4 %), vomiting (46.4 %) and abdominal pain (39.1 %) were the predominant clinical manifestations observed in our study. CONCLUSIONS Urinary tract infection is a common medical problem in children and it should be considered as a potential cause of fever in children. As febrile children with urinary tract infection usually present with non-specific signs and symptoms, urine culture should be considered as a part of diagnostic evaluation. KEYWORDS Urinary Tract Infections (UTI), Febrile Children, Bacteriological Profile, Urine Culture

scholarly journals A retrospective study on prevalence, bacteriological profile and antibiotic sensitivity pattern of urinary tract infection in children of 2-12 years age in a tertiary care centre, Puducherry, India

2019 ◽  
Vol 6 (5) ◽  
pp. 1818
Author(s):  
Dharmalingam Angamuthu ◽  
Chandru Bhaskar ◽  
Nalini Aswathaman
Keyword(s):  
Urinary Tract Infection ◽  
Retrospective Study ◽  
Urinary Tract ◽  
Tract Infection ◽  
Age Group ◽  
E Coli ◽  
Sensitivity Pattern ◽  
Female Predominance ◽  
Culture Positive ◽  
In Infants And Children

Background: Urinary tract infections (UTIs) are a common cause of acute bacterial illness in infants and children(1).Diagnosis is often missed in infants and children as urinary symptoms are minimal and nonspecific. It is becoming increasingly difficult to treat due to increasing prevalence of antimicrobial resistance among organisms.Method: It was done as a retrospective cross sectional study conducted on Children of 2-12 years of age suspected to have UTI  from January 2018 to December 2018 in Pediatric Department of AVMCH.Results: Out of 286 children with symptoms suggestive of Urinary tract infection, 22(7.7%) were found to have culture positive UTI with 9.2% prevalence in 2-6 years age group as against 6.4% in 7-12 years of age group. Culture positive UTI was predominantly found in males in 2-6 years age group as against female predominance in 7-12 years age group. E. coli (45.5%) was the commonest organism isolated among them followed by Klebsiella. 90% of organisms were sensitive to Nitrofurantoin  and 80% were sensitive to Amikacin(80%).Discussion: Culture positive UTI  rate varies with gender and age group. It was predominantly found in males in 2-6 years age group as against female predominance in 7-12 years age group. E. coli and Klebsieella were the most common organisms with predominant sensitivity to Nitrofurantoin and Amikacin similar to other studies. Limitation of this study Retrospective study, small sample size and follow up for complications not done.Conclusion: This study concludes E. coli and Klebsieella were the most common organisms with predominant sensitivity to Nitrofurantoin and Amikacin. Antibiotics need to be selected based on organisms and their sensitivity pattern.

Bacteriological Profile of Urinary Tract Infection of Children at GMC Teaching Hospital

2013 ◽  
Vol 3 (3) ◽  
pp. 22-25
Author(s):  
SP Shrestha ◽  
AK Shrestha ◽  
L Lamsal ◽  
M Joshi
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Teaching Hospital ◽  
Resistance Rate ◽  
E Coli ◽  
Medical College ◽  
Culture Positivity ◽  
Bacteriological Profile ◽  
Culture Positive

This study aimed to find bacterial profile of urinary tract infection (UTI) in children between 2 months to 15 years of age. This is a hospital based retrospective study conducted at Gandaki medical college and teaching hospital, Pokhara over a period of 18 months. Among the total 575 children enrolled for the study, 110 children (19.1%) were found to be culture positive. Most common age group having culture positivity is 1-5 years (40%). Present study showed that UTI is more common in girls (69.1%) than in boys (30.9%). E. coli was still the most commonly isolated bacteria (70.9%) followed by Proteus (20%), Klebsiella (5.4%) and Pseudomonas sp. in (1.8%). E. coli was sensitive to Nitrofurantoin (84.6 %), Amikacin (80.7%), Gentamicin (73%) and Ofloxacin in (53.8%). Most commonly used drugs for the treatment of UTI like Cefixime and Ceftriaxone was sensitive only in 15% and 10% respectively. Similarly, Klebsiella was sensitive to Amikacin and Gentamicin (100%) but sensitive to Nitrofurantoin in only 66% of cases. Proteus was sensitive to Nitrofurantoin (95.4%), Amikacin (86%) and to Gentamicin (59%). High resistance rate was observed to Cefixime and Ceftriaxone, the commonly used drugs for its treatment in OPD basis. DOI: http://dx.doi.org/10.3126/jcmc.v3i3.8633 Journal of Chitwan Medical College 2013; 3(3): 22-25

scholarly journals Emerging antibiotic resistance pattern of urinary tract infection (UTI) due to Escherichia Coli (E.Coli).

2021 ◽  
Vol 28 (12) ◽  
pp. 1804-1811
Author(s):  
Salman Azhar ◽  
Talha Munir ◽  
Mian Sajjad Ahmed ◽  
Wasif Baig ◽  
Ahmed Nawaz Baber ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Antibiotic Resistance ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urine Culture ◽  
Diffusion Method ◽  
Resistance Pattern ◽  
E Coli ◽  
Antibiotic Resistance Pattern ◽  
Culture And Sensitivity

Objective: To determine the emerging antibiotic resistance pattern of adult patients of MDR UTI cases caused by E.Coli. Study Design: Retrospective Data. Setting: Departments of Medicine and Obstetrics & Gynecology, Madinah Teaching Hospital / University Medical and Dental College, Faisalabad. Period: August 2016 to Sep 2018. Material & Methods: This retrospective study included 187 patients meeting the operational definition of multi-drug resistance cases of urinary tract infection caused by E. coli. All cases either male or female of age above 15 years with positive reports of urine culture and sensitivity for E.coli were included in the study. Along with the demographic variables urine WBC’s, results of urine culture and sensitivity were noted. Antibiotic sensitivity pattern of all the E.coli resistant UTI cases was analyzed. After identification of the microbe, antimicrobial sensitivity was accessed using Kirby–Bauer disc diffusion method on the Mueller–Hinton agar. The antimicrobial susceptibility test was performed against E. coli strains by using the following antibiotics: Piperacilin, Amoxicilin-Calvulanic, Pipmedic Acid, Cefipime, Ceftrixone, Cefuroxime, Cefoperazone-sulbactam, Ceftazidime, Cephradine, Ciprofloxacin, Ofloxacin, Levofloxacin, ofloxacin, Nitrofurantoin, Amikacin, Tombramycin, Gentamicin, Linezolid, Doxycycline, Sulphamethoxazole, Imipenem, Meropenem, Aztreonam in order to obtain an antibiogram. Results: In our data, 66.8% (n=125) were MDR UTI, and more than half of these cases were 63.2% (n=79) were females. Among the total 187 cases, 97.3% patients were resistant to most of the beta-lactam antibiotics, 95.7% were resistant to most of the quinolones and 68.4% were resistant to most of the aminoglycosides. Conclusion: This increasing antibiotic resistance is very alarming and steps should be taken to reduce the misuse of antibiotics. Studies should be done to control the risk factors leading to E. coli UTI. By following proper pharmacological guidelines, principles to use antibiotics and manage outpatient cases of UTIs, the incidence of MDR UTI can be controlled.

scholarly journals A STUDY ON THE BACTERIOLOGICAL PROFILE OF URINARY TRACT INFECTION INADULTS AND THEIR ANTIMICROBIAL SENSITIVITY PATTERN IN DMCH, LAHERIASARAI, BIHAR

2020 ◽  
pp. 31-32
Author(s):  
Neha Jha ◽  
R. S. Prasad ◽  
P. N. Jha ◽  
Debarshi Jana
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Antimicrobial Agents ◽  
Urine Culture ◽  
Positive Urine Culture ◽  
E Coli ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern ◽  
Positive Urine ◽  
Culture And Sensitivity

Background: Urinary tract infection is one of the most common bacterial infections in humans and a major cause of morbidity. The etiology of UTI and the antimicrobial sensitivity pattern varies with the widespread availability of antimicrobial agents; UTI has become difficult to treat because of appearance of pathogens with increasing resistance to antimicrobial agents. Methods: A descriptive study done during January 2020 to June 2020. All positive urine culture and sensitivity reports of males and females aged 20-70years were included. A total of 373 positive urine culture cases were taken from the culture and sensitivity register from Microbiology department and details were entered using a questionnaire. Results: Out of 373 adults, males were 137 (36.7%) and females were 236 (63.3%). E. coli (74.3 %) was the most common organism, followed by Klebsiella (15.8%), Enterococcus, Pseudomonas and Staphylococcus. The incidence of UTI was more in patients in the age group of 60-70years. E. coli and Klebsiella were sensitive to Amikacin (97.1%), Nitrofurantoin (90.7%), Gentamycin and Imipenem. Both organisms were resistant to Ampicillin (>90%). Conclusions: In this study, females were mostly affected and the most common organisms were E.Coli and Klebsiella. These organisms were most sensitive to Amikacin, Nitrofurantoin and resistant predominantly to Ampicillin. The sensitivity and resistance pattern of uropathogens to common antimicrobial agents must be taken into account when selecting treatment plans for UTI.

URINARY INFECTION AT DEPARTMENT OF UROLOGY OF HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL

2018 ◽  
pp. 100-108
Author(s):  
Dinh Khanh Le ◽  
Dinh Dam Le ◽  
Khoa Hung Nguyen ◽  
Xuan My Nguyen ◽  
Minh Nhat Vo ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urinary Tract Infections ◽  
Urine Culture ◽  
Clinical Manifestations ◽  
University Hospital ◽  
E Coli ◽  
Positive Urine ◽  
Tract Infections

Objectives: To investigate clinical characteristics, bacterial characteristics, drug resistance status in patients with urinary tract infections treated at Department of Urology, Hue University Hospital. Materials and Method: The study was conducted in 474 patients with urological disease treated at Department of Urology, Hue Universiry Hospital from July 2017 to April 2018. Urine culture was done in the patients with urine > 25 Leu/ul who have symptoms of urinary tract disease or infection symptoms. Patients with positive urine cultures were analyzed for clinical and bacterial characteristics. Results: 187/474 (39.5%) patients had symptoms associated with urinary tract infections. 85/474 (17.9%) patients were diagnosed with urinary tract infection. The positive urine culture rate was 45.5%. Symptoms of UTI were varied, and no prominent symptoms. E. coli accounts for the highest proportion (46.67%), followed by, Staphycoccus aureus (10.67%), Pseudomonas aeruginsa (8,0%), Streptococcus faecali and Proteus (2.67%). ESBL - producing E. coli was 69.23%, ESBL producing Enterobacter spp was 33.33%. Gram-negative bacteria are susceptible to meropenem, imipenem, amikacin while gram positive are vancomycin-sensitive. Conclusions: Clinical manifestations of urinary tract infections varied and its typical symptoms are unclear. E.coli is a common bacterium (46.67%). Isolated bacteria have a high rate of resistance to some common antibiotics especially the third generation cephalosporins and quinolones. Most bacteria are resistant to multiple antibiotics at the same time. Gram (+) bacteria are susceptible to vancomycin, and gram (-) bacteria are susceptible to cefoxitin, amikacin, and carbapenem. Key words: urinary tract infection

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