A study on the bacteriological profile of urinary tract infection in   adults and their antibiotic sensitivity pattern in a tertiary care hospital in central Kerala, India

Background: Urinary tract infection is one of the most common bacterial infections in humans and a major cause of morbidity. The etiology of UTI and the antibiotic sensitivity pattern varies with the widespread availability of antimicrobial agents; UTI has become difficult to treat because of appearance of pathogens with increasing resistance to antimicrobial agents.Methods: A descriptive study done during January-June 2013. All positive urine culture and sensitivity reports of males and females aged 20-70years were included. A total of 373 positive urine culture cases were taken from the culture and sensitivity register from Microbiology department and details were entered using a questionnaire.Results: Out of 373 adults, males were 137 (36.7%) and females were 236 (63.3%). E. coli (74.3 %) was the most common organism, followed by Klebsiella (15.8%), Enterococcus, Pseudomonas and Staphylococcus. The incidence of UTI was more in patients in the age group of 60-70years. E. coli and Klebsiella were sensitive to Amikacin (97.1%), Nitrofurantoin (90.7%), Gentamycin and Imipenem. Both organisms were resistant to Ampicillin (>90%).Conclusions: In this study, females were mostly affected and the most common organisms were E.Coli and Klebsiella. These organisms were most sensitive to Amikacin, Nitrofurantoin and resistant predominantly to Ampicillin. The sensitivity and resistance pattern of uropathogens to common antimicrobial agents must be taken into account when selecting treatment plans for UTI.

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A STUDY ON THE BACTERIOLOGICAL PROFILE OF URINARY TRACT INFECTION INADULTS AND THEIR ANTIMICROBIAL SENSITIVITY PATTERN IN DMCH, LAHERIASARAI, BIHAR

10.36106/ijsr/3725437 ◽

2020 ◽

pp. 31-32

Author(s):

Neha Jha ◽

R. S. Prasad ◽

P. N. Jha ◽

Debarshi Jana

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Antimicrobial Agents ◽

Urine Culture ◽

Positive Urine Culture ◽

E Coli ◽

Antimicrobial Sensitivity ◽

Sensitivity Pattern ◽

Positive Urine ◽

Culture And Sensitivity

Background: Urinary tract infection is one of the most common bacterial infections in humans and a major cause of morbidity. The etiology of UTI and the antimicrobial sensitivity pattern varies with the widespread availability of antimicrobial agents; UTI has become difficult to treat because of appearance of pathogens with increasing resistance to antimicrobial agents. Methods: A descriptive study done during January 2020 to June 2020. All positive urine culture and sensitivity reports of males and females aged 20-70years were included. A total of 373 positive urine culture cases were taken from the culture and sensitivity register from Microbiology department and details were entered using a questionnaire. Results: Out of 373 adults, males were 137 (36.7%) and females were 236 (63.3%). E. coli (74.3 %) was the most common organism, followed by Klebsiella (15.8%), Enterococcus, Pseudomonas and Staphylococcus. The incidence of UTI was more in patients in the age group of 60-70years. E. coli and Klebsiella were sensitive to Amikacin (97.1%), Nitrofurantoin (90.7%), Gentamycin and Imipenem. Both organisms were resistant to Ampicillin (>90%). Conclusions: In this study, females were mostly affected and the most common organisms were E.Coli and Klebsiella. These organisms were most sensitive to Amikacin, Nitrofurantoin and resistant predominantly to Ampicillin. The sensitivity and resistance pattern of uropathogens to common antimicrobial agents must be taken into account when selecting treatment plans for UTI.

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Bacteriological profile and antibiotic sensitivity pattern in patients with Urinary tract infection

Journal of Pathology of Nepal ◽

10.3126/jpn.v7i1.16910 ◽

2017 ◽

Vol 7 (1) ◽

pp. 1066-1069 ◽

Cited By ~ 1

Author(s):

N Subedi ◽

S Pudasaini

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Urine Culture ◽

Antibiotic Sensitivity ◽

Sensitivity Test ◽

Age Group ◽

E Coli ◽

Bacteriological Profile ◽

Culture And Sensitivity ◽

Culture Positive

Background: Urinary tract infection is one of the common bacterial infections seeking treatment in clinical practice. A variety of organisms are associated with UTI and the most common organisms are Escherichia coli and other coliforms. Bacteriological investigations of UTI are not complete without antibiotic sensitivity test of the isolate. The aim of this study is to determine the bacteriological profile and antibiotic sensitivity patterns and their disease association.Materials and methods: This study was conducted in Shankarapur Hospital over a period of one year. All cases of suspected UTI sent for urine culture and sensitivity test were evaluated in this study. Disease associated with UTI, bacteriological profile and antibiotic sensitivity patterns were evaluated.Results: A total of 974 cases were sent for urine culture and sensitivity test. The total culture positive cases were 165 (17.4%). The most common age group for culture positive test was 21- 30 years (33.3%) followed by 31- 40 years (25.5%). Female patients formed the majority of culture positive cases (84.8%) and E Coli (86.1%) was the most common organism isolated. Piperacillin- tazobactum and ceftriaxone were the most common antibiotic sensitive to the organisms. Simple uncomplicated UTI and PID were the most common indication for subjecting the patients to urine culture.Conclusion: UTI is most commonly seen in female of reproductive age group and the most common causative organism is E coli. Culture result and antibiogram helps the clinician for specific treatment of UTI.

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Clinical, Etiological and Antibiotic Susceptibility Profiles of Community-Acquired Urinary Tract Infection in a Western Hemisphere of Baghdad

Bangladesh Journal of Medical Science ◽

10.3329/bjms.v14i4.19071 ◽

2015 ◽

Vol 14 (4) ◽

pp. 352-358

Author(s):

Naser S Hussein

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Clinical Presentation ◽

Urine Culture ◽

Medical Science ◽

Antibiotic Sensitivity ◽

Western Hemisphere ◽

Positive Urine Culture ◽

Positive Urine

Background: In majority of community-acquired urinary tract infection (CA-UTI) cases, physicians can prescribe empirical therapy without a pretreatment urine culture especially in resource poor settings, where the cost of urine culture is more than cost of treatment itself. Objective: With growing problem of drug resistance globally as well as data on CA-UTI in Iraq are scare. We conduct this study to analyze clinical presentation, etiology and antibiotic sensitivity of bacteria causing community acquired urinary tract infection (CA-UTI). Material and Methods: Outpatients urine cultures and clinical presentations were collected from April 2012 to October 2012. A positive urine culture was defined as growth of a single bacteria with colony count of more than 100,000 CFU/ml and disk diffusion technique was performed to determine antibiotics susceptibility of isolated bacteria species. Clinical symptoms, causative uropathogens and their antibiotic sensitivity were recorded. Results: Of 299 urine cultures processed, a positive urine culture was detected in 100 subjects. Dysuria and bladder irritability (frequency and urgency) were the most common clinical presentation. 39% of isolated bacteria was Escherichia coli and Staphylococcus strains (30%). The isolated uropathogens showed a substantial sensitivity reduction to most of test antibiotics. Conclusion: Clinical presentation had a minor role in diagnosis of CA-UTI and this study revealed that E. coli and Staphylococcus strains were most prevalent isolated uropathogens. Susceptibility test showed there was a high sensitivity to nitrofurantoin, amikacin and imipenem.Bangladesh Journal of Medical Science Vol.14(4) 2015 p.352-358

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Antibiotic sensitivity pattern in urinary tract infection among adults in central part of Nepal

Journal of Chitwan Medical College ◽

10.3126/jcmc.v9i4.26894 ◽

2019 ◽

Vol 9 (4) ◽

pp. 18-23

Author(s):

Arun Sedhain ◽

Abja Sapkota ◽

Bidhan Shrestha

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urine Culture ◽

College Teaching ◽

Sensitivity Test ◽

E Coli ◽

Common Organism ◽

Sensitivity Pattern ◽

Culture And Sensitivity

Background: Urinary tract infection (UTI) is characterized by pathological invasion of the urinary tract by microorganisms. Majorities of organisms causing UTI are gram negative bacteria, most common of which is E. coli. Urine culture and sensitivity test is used to isolate the organism and to identify the susceptible drug of choice for appropriate treatment. This hospital-based study was carried out to analyze the spectrum and antibiotic susceptibility of microorganisms causing UTI. Methods: A retrospective study was done to analyze the results of urine culture and sensitivity test done at Chitwan Medical College Teaching Hospital over a period of two and half years. Standard guideline and protocol were used to collect the urine sample and to perform the test. Data analysis was done using SPSS version 21.0. Result: Out of 12, 925 urine samples submitted for culture and sensitivity test during the study period, bacterial pathogens were isolated from 3, 173 (24.54%) samples, which was significantly higher among females (28%) than the males (17%). The most common organism isolated on the culture was E. coli (68.5%) followed by Klebsiella (18.4%). Sensitivity of the uropathogens was seen highest with colistin (79.2%) followed by teicoplanin (64.58%), Aztreonam (63.25%) and Nitrofurantoin (61.16%). Most common antibiotics that showed resistance to the microorganisms in this study were Ampicillin (60.93%), Cotrimoxazole (53.72%), Cefixime (40.57%) and Levofloxacin (32.93%). Conclusions: This study has found a usual pattern of UTI with higher prevalence among females and E. coli being the most common organism. Nitrofurantoin has been found to have a good susceptibility for the treatment of UTI.

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Recent Antibiotic Sensitivity Pattern of Escherichia Coli in Urinary Tract Infection

TAJ Journal of Teachers Association ◽

10.3329/taj.v30i1.39125 ◽

2018 ◽

Vol 30 (1) ◽

pp. 61-65

Author(s):

Md Abdul Bari ◽

Mashiur Arefin ◽

Moriom Nessa ◽

Golam Mostofa ◽

Tafiqul Islam

Keyword(s):

Escherichia Coli ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urine Culture ◽

Antibiotic Sensitivity ◽

E Coli ◽

Sensitivity Pattern ◽

Marked Resistance ◽

Culture Positive

The objective of the study is to assess the recent sensitivity pattern of Escherichia coli in Urinary tract infection (UTI). Widespread use of antibiotics has led to the emergence of resistant microorganisms. As the antibiotic sensitivity patterns of the microorganisms are frequently changing, this retrospective analysis was designed to assess the recent antibiotic sensitivity pattern of Escherichia coli (E. coli) in urinary tract infection among the human population. Details of 358 urine culture positive reports for E. coli and their antibiotic sensitivity pattern pertaining to the study period of 6 months from Jan 2017 to June 2017 were collected from Microbiology Laboratory of Diagnostic Centers at Rajshahi and the results were statistically analyzed. The antibiotics tested for sensitivity were amikacin, gentamycin, ciprofloxacin, levofloxacin, cotrimoxazole, nitrofurantoin, ceftazidime, ceftriaxone and cefixime. The sensitivity pattern of E.coli to antibiotics in UTI was amikacin (82.68 gentamycin (75.97%), nitrofurantoin (70.67), levofloxacin (44.13%), ceftazidime (42.17%), co-trimoxazole (40.78%), ceftriaxone (38.54%), ciprofloxacin (35.75%), and cefixime (24.02%). The study highlighted the marked resistance of E. coli to quinolones and third generation cephalosporins.TAJ 2017; 30(1): 61-65

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Pattern of Antimicrobial Sensitivity of Organisms Causing Urinary Tract Infection in Nephrotic Syndrome in Children

Bangladesh Journal of Child Health ◽

10.3329/bjch.v40i3.33056 ◽

2017 ◽

Vol 40 (3) ◽

pp. 154-159

Author(s):

Tanuka Barua ◽

Sukhendu Shekhar Sen ◽

Jhulan Das Sharma ◽

Mahmood Ahmed Chowdhury Arzu ◽

Lutfanessa ◽

...

Keyword(s):

Urinary Tract Infection ◽

Nephrotic Syndrome ◽

Urinary Tract ◽

Tract Infection ◽

Antimicrobial Agents ◽

Urine Culture ◽

Culture Media ◽

E Coli ◽

Sensitivity Pattern ◽

Nephrotic Children

Background: Urinary tract infection (UTI) is a common infection in nephrotic syndrome children having a propensity for long term renal damage. Organisms causing UTI in nephrotic syndrome are becoming resistant to common antimicrobial agents and increase the morbidity and mortality. Surveillance of local antibiotic sensitivity pattern is necessary for proper management of UTI in nephrotic children.Objective: To see the pattern of antimicrobials sensitivity of organisms causing UTI in Nephrotic syndrome children.Methods: This was a hospital based cross-sectional study conducted in the department of Paediatrics, Chittagong Medical College Hospital, Chittagong from January 2009 to December 2009. 52 nephrotic children aged 2-6 years with typical clinical features were included. A clean catch midstream urine sample were collected in aseptic procedure and sent for inoculation in culture media. In case of collection failure, urine was collected by sterile catheterization. Bacterial isolates were tested for microbial sensitivity. Data regarding etiological organisms and antibiogram were analyzed using appropriate statistical method.Results: UTI was found in 30.8% nephrotic children. E-coli was the commonest organism isolated in urine culture followed by klebsiella. All organisms isolated on culture were more or less resistant to commonly used antibiotics except to amikacin. E coli were resistant to most of antibiotics and resistance to cotrimoxazol is quite high for all isolates. Ciprofloxacin as oral and amikacin as parenteral are good for first line treatment of UTI in nephrotic syndrome.Conclusion: Resistance among organisms causing UTI in nephrotic syndrome is an emergent problem now a day. Routine urine culture should be advised since treatment failure is likely to occur with commonly used antibiotics. Risk factor for emergence of antibiotic resistance of these pathogens should be evaluated.Bangladesh J Child Health 2016; VOL 40 (3) :154-159

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URINARY INFECTION AT DEPARTMENT OF UROLOGY OF HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2018.3.16 ◽

2018 ◽

pp. 100-108

Author(s):

Dinh Khanh Le ◽

Dinh Dam Le ◽

Khoa Hung Nguyen ◽

Xuan My Nguyen ◽

Minh Nhat Vo ◽

...

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Urine Culture ◽

Clinical Manifestations ◽

University Hospital ◽

E Coli ◽

Positive Urine ◽

Tract Infections

Objectives: To investigate clinical characteristics, bacterial characteristics, drug resistance status in patients with urinary tract infections treated at Department of Urology, Hue University Hospital. Materials and Method: The study was conducted in 474 patients with urological disease treated at Department of Urology, Hue Universiry Hospital from July 2017 to April 2018. Urine culture was done in the patients with urine > 25 Leu/ul who have symptoms of urinary tract disease or infection symptoms. Patients with positive urine cultures were analyzed for clinical and bacterial characteristics. Results: 187/474 (39.5%) patients had symptoms associated with urinary tract infections. 85/474 (17.9%) patients were diagnosed with urinary tract infection. The positive urine culture rate was 45.5%. Symptoms of UTI were varied, and no prominent symptoms. E. coli accounts for the highest proportion (46.67%), followed by, Staphycoccus aureus (10.67%), Pseudomonas aeruginsa (8,0%), Streptococcus faecali and Proteus (2.67%). ESBL - producing E. coli was 69.23%, ESBL producing Enterobacter spp was 33.33%. Gram-negative bacteria are susceptible to meropenem, imipenem, amikacin while gram positive are vancomycin-sensitive. Conclusions: Clinical manifestations of urinary tract infections varied and its typical symptoms are unclear. E.coli is a common bacterium (46.67%). Isolated bacteria have a high rate of resistance to some common antibiotics especially the third generation cephalosporins and quinolones. Most bacteria are resistant to multiple antibiotics at the same time. Gram (+) bacteria are susceptible to vancomycin, and gram (-) bacteria are susceptible to cefoxitin, amikacin, and carbapenem. Key words: urinary tract infection

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Incidence of Acute Pyelonephritis in Hospitalized Children under 5 Years Old with Positive Urine Culture

Universitas Médica ◽

10.11144/javeriana.umed59-4.piel ◽

2018 ◽

Vol 59 (4) ◽

pp. 1-5

Author(s):

Alexandra Castaño González ◽

Juan Gabriel Ruiz Peláez

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Acute Pyelonephritis ◽

Urine Culture ◽

Renal Scintigraphy ◽

Hospitalized Children ◽

Positive Urine Culture ◽

Positive Urine ◽

Urinary Culture

Introduction: Urinary tract infection is a major cause of child morbidity. The diagnosis of acute pyelonephritis is important to decide the treatment. Methods: Retrospective observational study. We collected information of urinalysis, urine Gram and urine culture of hospitalized children between 3 months and 5 years old, with suspected urinary tract infection between January 2008 and December 2010. In patients with positive urine culture, the results of renal scintigraphy (Gamma scan) were evaluated to estimate the incidence of acute pyelonephritis. Results: We identified 1,463 medical records. Urinary culture was obtained in 237 patients, of whom 54.4% were positive. Renal scintigraphy was obtained in 93 of these patients and 59.1% were positive. Conclusions: The incidence of acute pyelonephritis in patients with confirmed urinary tract infection was 59.1%.

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Impact of Constipation in Children on Urinary Tract Infection (UTI)

Bangladesh Journal of Child Health ◽

10.3329/bjch.v34i1.5697 ◽

1970 ◽

Vol 34 (1) ◽

pp. 17-20 ◽

Cited By ~ 1

Author(s):

Seikh Azimul Hoque ◽

Md Tariqul Islam ◽

Farid Ahmed ◽

Mohammed Hanif ◽

Shahnoor Islam ◽

...

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urine Culture ◽

Single Species ◽

Control Group ◽

Positive Urine Culture ◽

Positive Urine ◽

History Of ◽

The Difference

Objectives: The study was done to find out the relationship between constipation andurinary tract infection (UTI) in children.Methods: The study was a case control study between two groups in a tertiary carechildren hospital in Dhaka city. In group-1 (n=45) those children having history ofconstipation and in group-2 (n=78) as a control group having no history of constipationwere included in this study. Growths of a single species of organism with colony countof >105/ml in a clean-catch midstream single urine sample was considered as evidenceof urinary tract infection.Results: Positive urine culture was found in 8.9% (4/45) cases in children who hadhistory of constipation and 1.3% (1/78) in children who had no history of constipation.Though the number of positive urine culture was seven times more in children withconstipation than those who were not constipated but the difference between the twogroups was not statistically significant (p=0.059) .Conclusion: Culture documented UTI in children with constipation is seven timesmore than without constipation showing impact of constipation on urinary tract infection(UTI) in children.Key words: Urinary tract infection (UTI); constipation.DOI: 10.3329/bjch.v34i1.5697Bangladesh Journal of Child Health 2010; Vol.34(1): 17-20

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