scholarly journals Hepatoblastoma in an 18- Year Old Female; Rare Entity

2020 ◽  
Vol 3 (1) ◽  
pp. 320-322
Author(s):  
Daisy Maharjan ◽  
Deepshikha Gaire ◽  
Ram Chandra Adhikari

Hepatoblastoma is a rare malignant hepatic tumor in adults. It is associated with poor prognosis as it is usually diagnosed late when the tumor is completely unresectable. Presented here, is a case of an 18-year old female with pain abdomen, vomiting, and mass over the right hypochondriac region for one month. CT scan revealed soft tissue density mass on the right lobe of liver suggestive of focal nodular hyperplasia with differential diagnosis of atypical hemangioma. Liver angiography also suggested a vascular tumor of giant hemangioma with inferior exophytic extension. The patient underwent a right extended hepatectomy. Histopathological examination revealed hepatoblastoma with predominant fetal pattern and small focal areas of embryonal pattern. The patient had an uneventful postoperative recovery and is currently undergoing chemotherapy. We present this case for its rarity and ability to masquerade other primary liver tumors in the adult age as seen in our patient.

2017 ◽  
Vol 4 (4) ◽  
pp. 1478
Author(s):  
Digvijoy Sharma ◽  
Nagari Bheerappa ◽  
Venu Madhav Thumma ◽  
Suryaramchandra Varma ◽  
Kunduru Navakishore ◽  
...  

Hepatoblastoma (HB) is a rare malignant primary tumour of the liver and occurs mostly in the pediatric group within the first 3 years of life. It is extremely unusual to find hepatoblastoma in adults and is a very rare cause of primary malignant liver tumour in adults and due to this patient may be diagnosed at late stages of the disease at leading to poor prognosis in this group. Reported here a case of a 20-year-old boy with a large liver mass with abdominal pain. Triphasic CT revealed the presence of a large heterogenous tumor in the right lobe of liver suggestive of hepatocellular carcinoma. Patient underwent a right hepatectomy. Final histopathology was reported as Epithelial type hepatoblastoma. The patient had an uneventful post-operative recovery. We present this case for its rarity and ability to masquerade other primary liver tumors in the adult age as seen in our patient.


Author(s):  
Kotaro Matsumoto ◽  
Kentaro Kikuchi ◽  
Ayako Hara ◽  
Hiromichi Tsunashima ◽  
Koichi Tsuneyama ◽  
...  

AbstractA 25-year-old woman with fever and epigastric pain was referred to our hospital. Blood examination showed significant liver dysfunction, markedly high C-reactive protein (CRP 19.1 mg/dL) and procalcitonin (48.3 ng/mL) levels. Dynamic computed tomography showed a tumor approximately 120 mm in size in the right lobe of the liver, but with no abscess formation. The patient was hospitalized and started on antibiotics; her CRP level improved, but the procalcitonin level did not decrease. Histopathological examination of the liver tumor biopsy revealed fibrolamellar hepatocellular carcinoma (FLC). Positive staining of the FLC with an anti-procalcitonin antibody suggested the production of procalcitonin.


2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Luca Giovanella ◽  
Fabrizio Fasolini ◽  
Sergio Suriano ◽  
Luca Mazzucchelli

A 68-year-old woman with solid/trabecular follicular thyroid carcinoma inside of an autonomously functioning thyroid nodule is described in this paper. The patient was referred to our clinic for swelling of the neck and an increased pulse rate. Ultrasonography showed a slightly hypoechoic nodule in the right lobe of the thyroid. Despite suppressed TSH levels, the -pertechnetate scan showed a hot area corresponding to the nodule with a suppressed uptake in the remaining thyroid tissue. Histopathological examination of the nodule revealed a solid/trabecular follicular thyroid carcinoma. To the best of our knowledge, this is the first case of hyperfunctioning follicular solid/trabecular carcinoma reported in the literature. Even if a hyperfunctioning thyroid carcinoma is an extremely rare malignancy, careful management is recommended so that a malignancy will not be overlooked in the hot thyroid nodules.


2020 ◽  
Vol 26 (3) ◽  
pp. 30
Author(s):  
Elena Cantone ◽  
Aldo Torrisi ◽  
Antonio Romano ◽  
Antonia Cama ◽  
Giulia Foschi ◽  
...  

Introduction: We described a rare clinical case of osteoma associated with homolateral radicular cyst of the maxillary sinus. Observation: Imaging showed two different lesions in the right maxillary sinus. We performed a combined surgical approach to completely remove the lesions and used a plasma rich in growth factors membrane to repair dental roots. No relapse after a 2 years follow-up was observed. Commentaries: The simultaneous presence of two large lesions, a 23,7 mm osteoma and a 33,7 mm radicular cyst in the same maxillary sinus, has been rarely described in the literature. Although nasal endoscopy and imaging are mandatory to assess the diagnosis, the definitive diagnosis was obtained after histopathologic examination. A combined surgical approach allowed a complete removal of both lesions, ensuring, at same time, an optimal surgical field. Plasma rich in growth factors membrane due to its cohesive properties was particularly useful in improving bone neoformation and periodontal regeneration. Conclusion: Diagnostic assessment of maxillary lesions requires nasal endoscopy, imaging and histopathological examination. If these lesions are symptomatic, they should be completely removed and minimally invasive surgery is indicated. Plasma rich in growth factors membrane ensures a good postoperative recovery.


2020 ◽  
Vol 13 (1) ◽  
pp. 158-163
Author(s):  
Nicholas Pigg ◽  
Daniel Aboubechara ◽  
Roberto Fourzali ◽  
Brian Baigorri

Use of yttrium-90 (Y-90) is used for primary liver tumors and a handful of liver metastatic lesions. Y-90 treatment for metastatic adrenocortical carcinoma (ACC) to the liver is currently off-label, with one previously documented case report. In this case report, we present a 52-year-old woman with ACC and extensive liver metastatic disease. After failed chemotherapy, multidisciplinary discussion suggested potential Y-90 treatment for palliative purposes. After undergoing Y-90 treatment separately to the right and then the left hepatic lobes, subsequent patient visits demonstrated significantly improved clinical function as well as complete radiographic resolution of liver metastatic disease mainly from ACC. This case report demonstrates the potential efficacy of Y-90 for off-label uses in liver metastatic disease. This case and similar cases may open the door to a wide variety of potential indications for Y-90 treatment.


2013 ◽  
Vol 02 (02) ◽  
pp. 093-096
Author(s):  
P. Savithri

AbstractIn unusual cases of malrotation or incomplete rotation of caecum , the appendix is not located in the lower right quadrant. When the caecum is high [subhepatic caecum] the appendix is located in the right hypochondriac region and the pain in these cases is located there, not in the lower right quadrant. In this position , the symptoms and signs of acute appendicitis may mimic acute cholecystitis, diagnosis in such cases is a great diagnostic challenge. The author observed this less frequent anomaly in a middle aged male cadaver. After opening the abdomen while tracing peritoneal reflections abnormality was identified. The caecum and appendix were present in relation with inferior surface of liver. Embryologically, the caecal swelling appears as a small conical dilation of the caudal limb of primitive intestinal loop and it is the last part of the gut to reenter the abdominal cavity. It is temporarily located in the right upper quadrant directly below the right lobe of liver. From here it descends into the right iliac fossa. The failure to descend leads to subhepatic caecum.


2019 ◽  
Vol 2019 (12) ◽  
Author(s):  
Faisal Al-Zayer ◽  
Abdulla H Aljaroof ◽  
Maram Al-Marhoun ◽  
Basem Abualsaud ◽  
Mohammed Al-Zaher ◽  
...  

Abstract Diaphragmatic hernia in the absence of trauma in adults is very rare. It occurs as a result of unilateral diaphragmatic agenesis. The diagnosis of this rare condition is typically made in early infancy. However, in asymptomatic patients, the diagnosis is often delayed for months and even years. We present a case of a 27-year-old female, who was referred 48-hours after Caesarean section with suspected pulmonary embolism. Computed tomography scan revealed herniation of the liver as well as bowel loops into the right hemi-thorax. Exploration through a right thoracotomy revealed right diaphragmatic agenesis. The contents were reduced into the abdomen, and the defect was repaired using a mesh. The patient had an uneventful postoperative recovery and was discharged home 10 days later. This case highlights the acute late presentation of right diaphragmatic eventration with abdominal visceral herniation in adulthood. The condition may be triggered by the increasing size of gravid uterus.


2020 ◽  
Vol 16 (1) ◽  
Author(s):  
Moaied A. Hassan

Abstract Background Mesenchymal hamartoma is the second most common benign liver tumor in children, with 20% of the cases diagnosed during the neonatal period. The exact etiology in still unclear, and most investigators believe that it is a developmental anomaly rather than a true neoplasm. The presentation of these tumors is highly variable depending on the lesion’s size, ranging from small asymptomatic lesions to very large tumors with life threatening complications. Radical surgical excision, whenever possible, is the gold standard for treating these lesions to avoid the problems of local recurrence and possible malignant transformation. We present the rare occurrence of an entirely solid, giant hepatic mesenchymal hamartoma in a 3-week-old male newborn and discuss the mode of presentation, as well as the diagnostic and therapeutic approach. Case presentation A 3-week-old male newborn was referred to our institution with huge abdominal distension and respiratory distress. Imaging studies confirmed the presence of a very large solid intraabdominal mass occupying the majority of the abdominal cavity and abutting the inferior aspect of the right lobe of the liver, but did not reveal the diagnosis. At laparotomy, a huge solid mass was found attached to the right lobe of the liver. Complete excision was done, and histopathological examination confirmed the diagnosis of mesenchymal hamartoma. Conclusion Although rare, mesenchymal hamartoma of the liver can present as a neonatal surgical emergency. Emergency intervention is required in symptomatic patients. Radical surgical intervention is possible and is the treatment of choice to relieve the patient’s symptoms and avoid future complications.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Konstantinos G. Spiridakis ◽  
Mathaios E. Flamourakis ◽  
Ioannis G. Gkionis ◽  
Eleni I. Kaloeidi ◽  
Anthoula I. Fachouridi ◽  
...  

Abstract Background Diaphragmatic hernia involves protrusion of abdominal contents into the thorax through a defect in the diaphragm. This defect can be caused either by developmental failure of the posterolateral foramina to fuse properly, or by traumatic injury of the diaphragm. Left-sided diaphragmatic hernias are more common (80–90%) because the right pleuroperitoneal canal closes earlier and the liver protects the right diaphragm. Diaphragmatic hernias in adults are relatively asymptomatic, but in some cases may lead to incarcerated bowel, intraabdominal organ dysfunction, or severe pulmonary disease. The aim of this report is to enlighten clinical doctors about this rare entity that can have fatal consequences for the patient. Case presentation We present a rare case of a right-sided strangulating diaphragmatic hernia in an adult Caucasian patient without history of trauma. Clinical examination revealed bowel sounds in the right hemithorax, which were confirmed by the presence of loops of small intestine into the right part of the thorax through the right diaphragm, as was shown on chest X-ray and computerized tomography. Deterioration of the clinical status of the patient led to an operation, which revealed strangulated necrotic small bowel. Approximately 1 m of bowel was removed, and laterolateral anastomosis was performed. The patient had an uneventful postoperative recovery and was discharged 8 days later. Conclusions Surgery is required to replace emerged organs into the abdomen and to repair diaphragmatic lesion. A delayed approach can have catastrophic complications for a patient.


2018 ◽  
Vol 5 (7) ◽  
pp. 2679
Author(s):  
Sivakumar Thirunavukkarasu ◽  
Atreya M. Subramanian

Thyroid tuberculosis although known to be a rare entity provides a diagnostic challenge to the clinician. Clinically, radiologically and even histologically proving to be difficult to arrive at a diagnosis. Its incidence according to literature is 0.1-0.4%. Tuberculosis may be found at multiple sites but incidence in the thyroid, pancreas, striated and cardiac muscle is extremely rare. Herein, we discuss a case of a 60 year old female complaining of a swelling in the front of the neck (more on the right side) since 45 days. Clinically it appeared to be a thyroid swelling. An ultrasound showed a bulky right lobe with heterogeneous echoes. FNAC showed features suggestive of a follicular adenoma. Intraoperatively a firm thyroid was palpable and total thyroidectomy was done. Histopathological examination was done revealing langhan giant cells and an area of caseous necrosis, confirming tuberculosis. The patient was started on thyroid replacement therapy and anti-tubercular therapy. The patient had no significant complications in the 6 months follow up period. In tuberculosis endemic areas, one must maintain a high index of suspicion for thyroid swellings which may show foci of tuberculosis, especially if they have an elevated ESR and other foci of tuberculosis. 


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