scholarly journals Proximate Composition and Dietary Fiber Analyses of Heat-dried Pericarp of Citrus maxima and its Effect on Blood Glucose Levels in Rats

2018 ◽  
Vol 65 (10) ◽  
pp. 471-477
Author(s):  
Misato Nishioka ◽  
Shuko Toshima ◽  
Ryoko Yamamoto ◽  
Hideki Shiratsuchi ◽  
Hiroko Tomoyori
Foods ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 1500
Author(s):  
Hyeon-Ki Kim ◽  
Takuya Nanba ◽  
Mamiho Ozaki ◽  
Hanako Chijiki ◽  
Masaki Takahashi ◽  
...  

To examine the effects of the intake of a snack containing dietary fiber under free-living conditions on postprandial glucose levels in older adults, nine healthy older adults aged 76.9 ± 1.6 years (mean ± standard error) completed two crossover trials: 1) regular snack (BISCUIT) intake and 2) intake of snacks with a high dietary fiber content (DF-BISCUIT). In both trials, each participant consumed either BISCUIT or DF-BISCUIT between lunch and dinner time for 1 week. During the intervention, the blood glucose levels of all the subjects were observed using a continuous glucose monitoring system. Lower 24 h blood glucose levels were yielded in the DF-BISCUIT than the BISCUIT trials. Moreover, compared to the BISCUIT trials, the blood glucose levels after dinner and areas under the curve (AUCs) were significantly decreased in the DF-BISCUIT treatments. The blood glucose levels and AUCs after the intake of the next day’s breakfast were suppressed in the DF-BISCUIT treatments compared to those in the BISCUIT trials. Our data indicate that the intake of snacks with a high dietary fiber content under free-living conditions is an effective way to restrain postprandial glucose levels and that the effect lasts until breakfast the next day.


2021 ◽  
Vol 16 (1) ◽  
pp. 63
Author(s):  
Ellya Sinurat ◽  
Dina Fransiska ◽  
Sihono Sihono ◽  
Rinta Kusumawati

Rumput laut Ulva sp. memiliki kandungan serat pangan tinggi yang diketahui memiliki aktivitas hipoglikemik. Penelitian ini telah melakukan penambahan Ulva sp. pada biskuit sebagai makanan sehat yang kaya serat pangan. Tujuan penelitian untuk mengetahui pengaruh pemberian biskuit Ulva terhadap penurunan kadar glukosa darah pada tikus jantan yang diinduksi sukrosa jenuh. Selain itu, diamati profil hematologi dan biokimia klinis darah sebelum dan setelah pemberian biskuit Ulva. Uji antidiabetes dilakukan menggunakan uji toleransi glukosa oral terhadap tikus jantan yang diinduksi sukrosa jenuh. Biskuit Ulva yang diberikan 1 g/kg berat badan (BB) tikus dengan perlakuan kontrol negatif (pakan tanpa biskuit), biskuit tanpa Ulva sp., dan biskuit Ulva setara dengan Ulva sp. 1, 5, dan 10 mg/kg BB. Perlakuan dosis diberikan pada 5 ekor tikus percobaan sekali sehari selama 14 hari. Pengamatan terhadap intoleransi glukosa dilakukan melalui pengukuran glukosa darah setelah pemberian sukrosa jenuh ke semua perlakuan pada hari ke-14, dan diukur pada menit ke-0, 30, 60, dan 120. Penimbangan tikus dilakukan pada hari ke-0, 7, dan 14, sedangkan analisis hematologi dan biokimia klinis darah dilakukan pada hari ke-0 dan ke-14. Pemberian biskuit Ulva berpengaruh signifikan terhadap kadar glukosa darah, serta menurunkan hematokrit dan hemoglobin darah tikus. Biskuit dengan dosis Ulva setara 1 mg/kg BB mampu menurunkan kadar glukosa darah tikus secara efektif pada menit ke-60. Tidak ada perbedaan kenaikan berat badan tikus jantan antara kelompok kontrol negatif dan biskuit Ulva pada hari ke-0, 7, dan 14. Pemberian biskuit Ulva sampai dengan 10 mg/kg BB tidak mempengaruhi SGOT, SGPT, ureum, dan kreatinin tikus. ABSTRACTSeaweed Ulva sp. contains high dietary fiber which is known to have hypoglycemic activity. In this study, the addition of Ulva sp. in biscuit products as a healthy food rich in dietary fiber. The objective of this study was to determine the effect of Ulva added biscuits on blood glucose levels reduction in male rats induced by saturated sucrose. In addition, clinical hematology and blood biochemical profiles before and after the administration of Ulva biscuits were also observed. Antidiabetic method used the oral glucose intolerance test method on male rats induced by saturated sucrose. Ulva biscuits were given at 1 g/kg body weight of rats for each treatment. This test used five treatments, namely negative control (rats feeding without biscuits), rat feeding without Ulva added biscuits; and rat feeding with Ulva biscuits equivalent to 1, 5, and 10 mg Ulva sp. /kg BW. Each dose treatment was given to five experimental rats once a day for 14 days. Observations on glucose intolerance included measurement of blood glucose levels by giving saturated sucrose to all treatments and measured at 0, 30, 60, and 120 minutes after administration of saturated sucrose. The weighing was carried out on day 0, 7, and 14, while clinical hematological and blood biochemical analyzes were performed on day 0 and 14. The administration of Ulva biscuits had a significant effect on the blood glucose levels of male rats, lowering  hematocrit and hemoglobin in rat blood. The concentration of 0.1% Ulva biscuits in biscuits (equivalent to a dose of Ulva sp. 1 mg/kg BW) was able to effectively reduce the blood glucose levels of rats after 60 minutes. There was no difference in weight gain of male rats between the negative control group and Ulva biscuits on days 0, 7, and 14. The diet of Ulva biscuits with 10 mg/kg BW Ulva sp. did not affect the SGOT, SGPT, urea, and creatinine of rats.


2020 ◽  
Author(s):  
Kazunari Kadokura ◽  
Tsuyoshi Tomita ◽  
Sachiyo Hata ◽  
Kazuhiko Kamata ◽  
Kohei Suruga

Abstract Background: Low-carbohydrate diets are popular nutritional therapeutics based on recommendations of the American Diabetes Association (2013). In previous reports, we suggested a new diet-intake restriction method using low-sugar, high-dietary fiber noodles containing okara and konjac and reported their effect on blood glucose levels in healthy animals and animal models of type 2 diabetes. This study aimed to compare the effect of low-sugar, high-dietary fiber noodles with that of normal wheat noodles on glycemic response in healthy adult men.Methods: The study was a randomized, cross-over design to investigate the effects of normal wheat noodles versus low-sugar, high-dietary fiber noodles on glucose and insulin responses at 120 min. Plasma glucose and insulin levels were measured at 0, 15, 30, 45, 60, and 120 min after intake of normal wheat noodles or low-sugar, high-dietary fiber noodles.Results: No abnormalities and side effects were observed in the low-sugar, high-dietary fiber noodles group. Additionally, in men who consumed low-sugar, high-dietary fiber noodles, the increase in postprandial blood glucose levels and insulin levels was significantly suppressed compared with that in men who consumed normal wheat noodles. Conclusions: To the best of our knowledge, this is the first report on the effectiveness of low-sugar, high-dietary fiber noodles on postprandial blood glucose levels in healthy humans; our findings also suggest that such type of noodles might be beneficial for patients with diabetes or celiac disease who consume noodles.Trial registration: UMIN000023986


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2253-PUB
Author(s):  
KOHEI SURUGA ◽  
KAZUNARI KADOKURA ◽  
AYAKA MIYATA ◽  
TSUYOSHI TOMITA ◽  
YOSHIHIRO SEKINO ◽  
...  

2006 ◽  
Vol 31 (03) ◽  
Author(s):  
H Hager ◽  
E Giorni ◽  
A Felli ◽  
B Mora ◽  
M Hiesmayr ◽  
...  

2017 ◽  
Author(s):  
Ina Darashkevich ◽  
Tatiana Mochort ◽  
Lola Niconova ◽  
Serhey Tishkovsky

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1167-P
Author(s):  
HUN-SUNG KIM ◽  
EUN YOUNG LEE ◽  
KUN-HO YOON

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