Effect of Low-Available Carbohydrate Diet with High Dietary Fiber Using Okara and Konjac on Blood Glucose Levels in Mice

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 2253-PUB
Author(s):  
KOHEI SURUGA ◽  
KAZUNARI KADOKURA ◽  
AYAKA MIYATA ◽  
TSUYOSHI TOMITA ◽  
YOSHIHIRO SEKINO ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Dietary Fiber ◽  
Carbohydrate Diet ◽  
Glucose Levels ◽  
Blood Glucose Levels

2167-PUB: Effect of Low-Available Carbohydrate Diet Containing Okara and Konjac on Blood Glucose Levels in Spontaneous Diabetic Torii Fatty Rats

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 2167-PUB
Author(s):  
KOHEI SURUGA ◽  
TSUYOSHI TOMITA ◽  
MASAKAZU KOBAYASHI ◽  
TADAHIKO MITSUI ◽  
KAZUNARI KADOKURA
Keyword(s):  
Blood Glucose ◽  
Carbohydrate Diet ◽  
Glucose Levels ◽  
Blood Glucose Levels

The Effect of Yacon Leaf Powder (Smallanthus Sonchifolius) on White Rats (Rattus norvegicus) Blood Glucose Levels with High Sugar Diet

2021 ◽  
Vol 8 (2) ◽  
pp. 217-220
Author(s):  
Thatit Nurmawati ◽  
Sandi Alfa Wiga Arsa ◽  
Nawang Wulandari ◽  
Agus Saparudin
Keyword(s):  
Blood Glucose ◽  
Treatment Group ◽  
Carbohydrate Diet ◽  
Glucose Levels ◽  
Smallanthus Sonchifolius ◽  
High Carbohydrate ◽  
White Rats ◽  
Blood Glucose Levels ◽  
Treatment Dose ◽  
Significant Difference

Maintaining a lifestyle can reduce the incidence of DM (diabetes mellitus). DM occurs due to insulin disorders so that blood glucose levels increase, which can lead to various complications. The management of blood glucose levels by activating the insulin function can be done by using natural ingredients such as the Yakon (Smallanthus sonchifolius) plant. Yakon leaves contain phenol which can reduce blood glucose. The design of this study was experimental with a pre-posttest approach with control-group design, using male and healthy white rats (Rattus norvegicus). Rats were divided into 3 groups, treatment dose 1, treatment dose 2 and control. The rats were given a high carbohydrate diet during 9 weeks to make the rats hyperglycemic. In the treatment group, dose 1 was 150 mg/kg BW, dose 2 was 300 mg kg BW, and was given for 3 days. The results showed that the rats in the treatment group dose 1 had decreased in the average blood sugar level of 114.10 mg / dl (p 0.002) and dose 2 was 105.27 mg / dl (p 0.005). This showed that there was an effect of treatments on blood sugar levels. The comparison results showed that there was a significant difference between the dose 1, the dose 2 group and the control (Sig. (2-tailed) = 0.001 (α) = 0.05). There was no significant difference in the treatment group dose 1 and treatment dose 2 (Sig. (2-tailed) = 0.693, (α) = 0.05). Yakon leaves can be used alternative to lower to control blood glucose levels in rats receiving a high-carbohydrate diet

scholarly journals Effect of the Intake of a Snack Containing Dietary Fiber on Postprandial Glucose Levels

Foods ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 1500
Author(s):  
Hyeon-Ki Kim ◽  
Takuya Nanba ◽  
Mamiho Ozaki ◽  
Hanako Chijiki ◽  
Masaki Takahashi ◽  
...  
Keyword(s):  
Older Adults ◽  
Blood Glucose ◽  
Dietary Fiber ◽  
Postprandial Glucose ◽  
Living Conditions ◽  
Fiber Content ◽  
Free Living ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Free Living Conditions

To examine the effects of the intake of a snack containing dietary fiber under free-living conditions on postprandial glucose levels in older adults, nine healthy older adults aged 76.9 ± 1.6 years (mean ± standard error) completed two crossover trials: 1) regular snack (BISCUIT) intake and 2) intake of snacks with a high dietary fiber content (DF-BISCUIT). In both trials, each participant consumed either BISCUIT or DF-BISCUIT between lunch and dinner time for 1 week. During the intervention, the blood glucose levels of all the subjects were observed using a continuous glucose monitoring system. Lower 24 h blood glucose levels were yielded in the DF-BISCUIT than the BISCUIT trials. Moreover, compared to the BISCUIT trials, the blood glucose levels after dinner and areas under the curve (AUCs) were significantly decreased in the DF-BISCUIT treatments. The blood glucose levels and AUCs after the intake of the next day’s breakfast were suppressed in the DF-BISCUIT treatments compared to those in the BISCUIT trials. Our data indicate that the intake of snacks with a high dietary fiber content under free-living conditions is an effective way to restrain postprandial glucose levels and that the effect lasts until breakfast the next day.

scholarly journals Proximate Composition and Dietary Fiber Analyses of Heat-dried Pericarp of Citrus maxima and its Effect on Blood Glucose Levels in Rats

2018 ◽  
Vol 65 (10) ◽  
pp. 471-477
Author(s):  
Misato Nishioka ◽  
Shuko Toshima ◽  
Ryoko Yamamoto ◽  
Hideki Shiratsuchi ◽  
Hiroko Tomoyori
Keyword(s):  
Blood Glucose ◽  
Dietary Fiber ◽  
Proximate Composition ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Citrus Maxima

scholarly journals Efek Pemberian Biskuit Ulva terhadap Penurunan Kadar Glukosa Darah Tikus yang Diinduksi Sukrosa

2021 ◽  
Vol 16 (1) ◽  
pp. 63
Author(s):  
Ellya Sinurat ◽  
Dina Fransiska ◽  
Sihono Sihono ◽  
Rinta Kusumawati
Keyword(s):  
Blood Glucose ◽  
Dietary Fiber ◽  
Glucose Intolerance ◽  
Negative Control ◽  
Test Method ◽  
Male Rats ◽  
Oral Glucose ◽  
Glucose Levels ◽  
Blood Biochemical ◽  
Blood Glucose Levels

Rumput laut Ulva sp. memiliki kandungan serat pangan tinggi yang diketahui memiliki aktivitas hipoglikemik. Penelitian ini telah melakukan penambahan Ulva sp. pada biskuit sebagai makanan sehat yang kaya serat pangan. Tujuan penelitian untuk mengetahui pengaruh pemberian biskuit Ulva terhadap penurunan kadar glukosa darah pada tikus jantan yang diinduksi sukrosa jenuh. Selain itu, diamati profil hematologi dan biokimia klinis darah sebelum dan setelah pemberian biskuit Ulva. Uji antidiabetes dilakukan menggunakan uji toleransi glukosa oral terhadap tikus jantan yang diinduksi sukrosa jenuh. Biskuit Ulva yang diberikan 1 g/kg berat badan (BB) tikus dengan perlakuan kontrol negatif (pakan tanpa biskuit), biskuit tanpa Ulva sp., dan biskuit Ulva setara dengan Ulva sp. 1, 5, dan 10 mg/kg BB. Perlakuan dosis diberikan pada 5 ekor tikus percobaan sekali sehari selama 14 hari. Pengamatan terhadap intoleransi glukosa dilakukan melalui pengukuran glukosa darah setelah pemberian sukrosa jenuh ke semua perlakuan pada hari ke-14, dan diukur pada menit ke-0, 30, 60, dan 120. Penimbangan tikus dilakukan pada hari ke-0, 7, dan 14, sedangkan analisis hematologi dan biokimia klinis darah dilakukan pada hari ke-0 dan ke-14. Pemberian biskuit Ulva berpengaruh signifikan terhadap kadar glukosa darah, serta menurunkan hematokrit dan hemoglobin darah tikus. Biskuit dengan dosis Ulva setara 1 mg/kg BB mampu menurunkan kadar glukosa darah tikus secara efektif pada menit ke-60. Tidak ada perbedaan kenaikan berat badan tikus jantan antara kelompok kontrol negatif dan biskuit Ulva pada hari ke-0, 7, dan 14. Pemberian biskuit Ulva sampai dengan 10 mg/kg BB tidak mempengaruhi SGOT, SGPT, ureum, dan kreatinin tikus. ABSTRACTSeaweed Ulva sp. contains high dietary fiber which is known to have hypoglycemic activity. In this study, the addition of Ulva sp. in biscuit products as a healthy food rich in dietary fiber. The objective of this study was to determine the effect of Ulva added biscuits on blood glucose levels reduction in male rats induced by saturated sucrose. In addition, clinical hematology and blood biochemical profiles before and after the administration of Ulva biscuits were also observed. Antidiabetic method used the oral glucose intolerance test method on male rats induced by saturated sucrose. Ulva biscuits were given at 1 g/kg body weight of rats for each treatment. This test used five treatments, namely negative control (rats feeding without biscuits), rat feeding without Ulva added biscuits; and rat feeding with Ulva biscuits equivalent to 1, 5, and 10 mg Ulva sp. /kg BW. Each dose treatment was given to five experimental rats once a day for 14 days. Observations on glucose intolerance included measurement of blood glucose levels by giving saturated sucrose to all treatments and measured at 0, 30, 60, and 120 minutes after administration of saturated sucrose. The weighing was carried out on day 0, 7, and 14, while clinical hematological and blood biochemical analyzes were performed on day 0 and 14. The administration of Ulva biscuits had a significant effect on the blood glucose levels of male rats, lowering  hematocrit and hemoglobin in rat blood. The concentration of 0.1% Ulva biscuits in biscuits (equivalent to a dose of Ulva sp. 1 mg/kg BW) was able to effectively reduce the blood glucose levels of rats after 60 minutes. There was no difference in weight gain of male rats between the negative control group and Ulva biscuits on days 0, 7, and 14. The diet of Ulva biscuits with 10 mg/kg BW Ulva sp. did not affect the SGOT, SGPT, urea, and creatinine of rats.

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