Guardrail Need: Embankments and Culverts

Author(s):  
Dan Wolford ◽  
Dean L. Sicking

A cost-effectiveness analysis was used to study safety-treatment options for embankments and culverts on resurfacing, restoration, and rehabilitation (3R) projects. An examination of the need for cable and W-beam guardrails to shield traffic from roadside embankments and roadside culverts, respectively, was made. Average embankment and culvert accident severities were estimated using Highway Safety Information System data from Utah and Michigan. Average accident severities were calibrated through computer simulations of ran-off-road accidents. Simplified design charts were developed to allow highway engineers to quickly determine the need for cable guardrail on 3R projects.

SAGE Open ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 215824402093992
Author(s):  
Xiuguang Song ◽  
Jianqing Wu ◽  
Hongbo Zhang ◽  
Rendong Pi

Crash severity, as a major concern in the routing and scheduling of hazardous material shipments, has caused great loss of lives and property damage every year. Although abundant studies have been conducted to identify the relationship between different factors on crash severity, the analysis of the severity of hazard material transportation (HMT) crashes is very limited. Factors including road, vehicle, driver, and environment are not well considered in previous studies. This article analyzed the influence of various factors on HMT crash severity using Highway Safety Information System data. The random forest combined with the ordered logistic model is used for factor analysis. The results showed that annual average daily traffic, fatigues/asleep, number of lanes, speeding, adverse weather, and light are the six most important factors affecting HMT crash severity. Different from the non-HMT crashes, driver factor (e.g., driver age, gender, and drug/alcohol influence) was found to be not significantly related to crash severity. Speeding should be strictly forbidden for HMT drivers, considering the potential increased crash severity. Increasing the level of lighting can help reduce the number of severe crashes. The corresponding recommendations were provided based on the regression results.


2021 ◽  
Author(s):  
Ronald Chow ◽  
Elizabeth Horn Prsic ◽  
Hyun Joon Shin

Introduction: A recent systematic review and meta-analysis by our group reported on thirteen published cohorts investigating 110,078 patients. Patients administered statins after their COVID-19 diagnosis and hospitalization were found to have a lower risk of mortality. Given this reported superiority, a logical next question would be whether statins are cost-effective treatment options for hospitalized COVID-19 patients. In this paper, we report on a cost-effectiveness analysis of statin-containing treatment regimens for hospitalized COVID-19 patients, from a United States healthcare perspective. Methods: A Markov model was used, to compare statin use and no statin use among hospitalized COVID-19 patients. The cycle length was one week, with a time horizon of 4 weeks. A Monte Carlo microsimulation, with 20,000 samples were used. All analyses were conducted using TreeAge Pro Healthcare Version 2021 R1.1. Results: Treatment of hospitalized COVID-19 patients with statins was both cheaper and more effective than treatment without statins; statin-containing therapy dominates over non-statin therapy. Conclusion: Statin for treatment of COVID-19 should be further investigated in RCTs, especially considering its cost-effective nature. Optimistically and pending the results of future RCTs, statins may also be used broadly for treatment of hospitalized COVID-19 patients.


PHARMACON ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 968
Author(s):  
Monica D. Lestari ◽  
Gayatri Citraningtyas ◽  
Hosea Jaya Edi

ABSTRACTPneumonia is an infectious disease in the lower respiratory tract that affects the lung tissue. Ceftriaxone and Gentamicin antibiotics are the most numerous and good for use in the treatment of pneumonia, but of the two antibiotics is not yet known the options for more cost effective treatment, so it needs to be done the cost effectiveness analysis in order to facilitate the selection of more cost-effective treatment options especially in toddler. This study aims to determine which therapies are more cost-effective than the use of antibiotics Ceftriaxone and Gentamicin in pneumonia patients in the January-December 2018 period in the Bhayangkara Manado Hospital using descriptive research methods with retrospective data collection. The sample in this study were 22 patients, 12 patients using ceftriaxone antibiotics and 10 patients using gentamicin antibiotics. The results showed that pneumonia treatment in infants using Ceftriaxone antibiotics was more cost-effective with ACER ceftriaxone value of Rp. 503,872 / day and ICER value of Rp. 145,588 / day. Keywords : Antibiotics, CEA (Cost-Effectiveness Analysis), Pharmacoeconomy, Toddler Pneumonia. ABSTRAKPneumonia merupakan penyakit infeksi pada saluran pernapasan bagian bawah yang mengenai jaringan paru. Antibiotik Seftriakson dan Gentamisim yang paling banyak dan baik untuk digunakan dalam pengobatan pneumonia, namun dari kedua antibiotik tersebut belum diketahui pilihan terapi yang lebih cost-effective, sehingga perlu dilakukan analisis efektivitas biaya agar dapat mempermudah dalam pemilihan alternatif pengobatan yang lebih cost-effective khususnya pada balita. Penelitian ini bertujuan untuk menentukan terapi yang lebih cost-effective dari penggunaan antibiotik Seftriakson dan Gentamisin pada pasien pneumonia rawat inap periode Januari-Desember 2018 di Rumah Sakit Bhayangkara Manado dengan menggunakan metode penelitian deskriptif dengan pengambilan data secara retrospektif. Sampel pada penelitian ini sebanyak 22 pasien yaitu 12 pasien menggunakan antibiotik Seftriakson dan 10 pasien menggunakan antibiotik Gentamisin. Hasil penelitian menunjukkan pengobatan pneumonia pada balita menggunakan antibiotik Seftriakson lebih cost-effective dengan nilai ACER seftriakson sebesar Rp. 503,872/hari dan nilai ICER sebesar Rp. 145.588/hari. Kata Kunci : Pneumonia Balita, Antibiotik, CEA (Cost-Effectiveness Analysis), Farmakoekonomi


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