scholarly journals ULTRASTRUCTURAL CHARACTERISTICS OF THE LARYNGEAL MUCOSA AND CARTILAGE RAT IS NORMAL

World Science ◽  
2021 ◽  
Author(s):  
Ivasivka K. P.
Keyword(s):  
Mucous Membrane ◽  
Fundamental Study ◽  
Laryngeal Cartilage ◽  
Laryngeal Mucosa ◽  
The Future ◽  
Ultrastructural Characteristics ◽  
And Cartilage

In our work, the aim was to conduct a fundamental study of the issue concerning the ultrastructural characteristics of the mucous membrane and cartilaginous corset of the rat larynx in the norm.This information in the future will make it possible to form a base that will be used to compare the components of the mucosa and laryngeal cartilage in the norm with the dynamics of their changes as a result of experimental opioid exposure.

Dynamics of changes in the structural components of the mucosa and cartilage of the larynx of rats at the end of 28th and 35th days of experimental opioid exposure

2021 ◽  
pp. 79-88
Author(s):  
Khrystyna P. Ivasivka ◽  
Evgeniy V. Paltov ◽  
Zoryana Z. Masna ◽  
Yuri Ya. Kryvko ◽  
Maryana B. Cherkes
Keyword(s):  
Mucous Membrane ◽  
Structural Components ◽  
Fundamental Study ◽  
The Future ◽  
And Cartilage

In our work we aimed to conduct a fundamental study of the process of morphological disorganization of the structural components of the mucous membrane and cartilage of the larynx at the end of the 28 and 35 days of experimental opioid effects at the microstructural level. This information in the future will allow to form a pathomorphological base, which will be used to compare the components of the mucous membrane and cartilage of the larynx in the norm with the dynamics of their changes as a result of experimental opioid effects at different times.

scholarly journals PATHOMORPHOLOGICAL CHARACTERISTICS OF CHANGES IN THE STRUCTURAL COMPONENTS OF THE MUCOSA AND CARTILAGE OF THE LARYNX OF RATS AT THE END OF THE SEVENTH DAY OF THE EXPERIMENTAL OPIOID EFFECT

2021 ◽  
Author(s):  
Ivasivka K. P. ◽  
Paltov E. V. ◽  
Masna Z. Z.
Keyword(s):  
Mucous Membrane ◽  
Structural Components ◽  
Fundamental Study ◽  
The Future ◽  
And Cartilage

In our work we aimed to conduct a fundamental study of the process of morphological disorganization of the structural components of the mucous membrane and cartilage of the larynx at the end of the seventh day of experimental opioid effects at the microstructural level. This information in the future will allow to form a pathomorphological base, which will be used to compare the components of the mucous membrane and cartilage of the larynx in the norm with the dynamics of their changes as a result of experimental opioid effects at different times.

scholarly journals CHARACTERISTICS OF THE STRUCTURAL COMPONENTS OF THE MUCOSA AND CARTILAGE OF THE LARYNX OF RATS IN NORMAL

World Science ◽  
2021 ◽  
Author(s):  
Ivasivka Kh. P. ◽  
Paltov E. V. ◽  
Masna Z. Z.
Keyword(s):  
Mucous Membrane ◽  
Structural Components ◽  
Fundamental Study ◽  
Morphological Organization ◽  
The Future ◽  
And Cartilage

The aim was to conduct a fundamental study of the issue concerning the morphological organization of the mucous membrane and cartilaginous corset of the rat larynx in the norm. Our goal is achieved through the use of morphological methods of preparation and microstructural research.This information in the future will allow to form a morphological base, which will be used to compare the components of the mucous membrane and cartilage of the larynx in the norm with the dynamics of their changes as a result of experimental opioid exposure.

scholarly journals Dynamics of changes in the ultrastructural characteristics of the mucosa and cartilage of the larynx of rats at the end of 35 and 42 days of experimental opioid exposure and after 56 days with opioid withdrawal

2021 ◽  
Vol 11 (9) ◽  
pp. 841-851
Author(s):  
K. Ivasivka ◽  
E. Paltov ◽  
Z. Masna ◽  
I. Chelpanova
Keyword(s):  
Mucous Membrane ◽  
Opioid Analgesic ◽  
Ultrastructural Level ◽  
Opioid Withdrawal ◽  
Ultrastructural Organization ◽  
National Medical ◽  
Laryngeal Mucosa ◽  
Medical University ◽  
And Cartilage ◽  
Different Parts

In our work, we studied the ultrastructural organization of rat laryngeal mucosa and cartilage at the end of 35 and 42 days of experimental opioid exposure and at the end of 56 days with opioid withdrawal. As a result of our study at the end of the 35th day at the ultrastructural level revealed hypersecretion of goblet cells, mucus contained impurities of lymphocytes, single neutrophils and erythrocytes. In the enlarged lumens of the hemocapillaries of the lamina propria of the mucous membrane and submucosal base of different parts of the larynx, the adhesion of erythrocytes was noted. At the end of 42 days in rats, the changes were characterized by moderate damage to cytoplasmic organelles in epitheliocytes. Alternative changes developed in the chondrocytes of elastic and hyaline cartilages. Marked by an increase in the number of active fibroblasts, next to which were numerous fibrils of collagen fibers. The main substance of connective tissue, near dilated vessels, was impregnated with transudate, which was accompanied by the development of perivasal edema. Glycogen grains and vacuoles filled with neutral fats were visualized in the cytoplasm of chondrocytes.At the end of 56 days in rats with two-week withdrawal of the opioid analgesic, we found the development of alternative processes in the epitheliocytes of different parts of the larynx, as well as in chondrocytes, especially in elastic cartilage. Dyscirculatory processes in vessels of own plate of a mucous membrane and a submucous basis of various departments of a larynx were registered. Necrotic changes developed in the columnar epitheliocytes of the submucosal mucosa. Mitochondria swelled, their matrix brightened, cristae collapsed. The results of the article correspond to the research plan of  Danylo Halytskyi Lviv National Medical University and are part of the research topic of the Department of Normal Anatomy "Morphofunctional features of organs in pre - and postnatal periods of ontogenesis, under the influence of opioids, food supplements, reconstructive surgery and obesity" 0120U002129) during 2020 - 2024.

scholarly journals Dynamics of changes in the structural components of the mucosa and cartilage of the larynx of rats at the end of 42 days of experimental opioid exposure and after 56 days with opioid withdrawal

2021 ◽  
Vol 11 (7) ◽  
pp. 201-218
Author(s):  
Khrystyna Ivasivka
Keyword(s):  
Mucous Membrane ◽  
Apical Part ◽  
Structural Components ◽  
Histological Techniques ◽  
Laryngeal Mucosa ◽  
Pas Reaction ◽  
Experimental Group ◽  
Hematoxylin Eosin ◽  
And Cartilage ◽  
Excessive Accumulation

In our work we aimed to study the pathomorphological manifestations among the structural components of the laryngeal mucosa and cartilage in the later stages of the experimental opioid effect. This goal was achieved through the use of histological techniques to visualize the structural components of the laryngeal mucosa and cartilage. Histological sections with a thickness of 5 -7 mm were made. Histological specimens were prepared according to conventional methods using the dye hematoxylin, eosin, azan according to the method of Heidenhain, PAS-reaction according to Mc-Manus and Alcian blue according to Steedman. Microscopic examinations and photographing of the preparations were performed using an MBI-1 microscope and a Nicon D 3100 digital camera.At the end of 42 days of experimental exposure, the epithelial layer of the epiglottis was inhomogeneously thickened, with excessive accumulation on its pharyngeal and apical part of the stratum corneum. Individual epitheliocytes of the pharyngeal part of the epiglottis underwent necrotic changes, the horny substance loosened in places. On the pharyngeal surface of the mucous membrane found a small amount of mucus with impurities of erythrocytes. Dyscirculatory processes were also registered in the animals of the experimental group. In particular, dilatation and overflow of erythrocytes of vessels of own plate of a mucous membrane of an epiglottis, and also polymorphonuclear infiltration of own plate of a mucous membrane were observed.

scholarly journals Fundamental Study of the Etiology of Abnormal Sensations of the Larynx; Nerve Endings in the Laryngeal Mucosa

1988 ◽  
Vol 1988 (Supplement23) ◽  
pp. 18-23
Author(s):  
Takemoto Shin ◽  
Shigeru Wada ◽  
Michiru Kawasoe ◽  
Tadatsugu Maeyama
Keyword(s):  
Nerve Endings ◽  
Fundamental Study ◽  
Laryngeal Mucosa

scholarly journals Morphometric characteristics of the mucous membrane and the cartilaginous component of the larynx are normal at different times during the experimental opioid effect and during withdrawal

Morphologia ◽  
2021 ◽  
Vol 15 (2) ◽  
pp. 25-30
Author(s):  
K.P. Ivasivka ◽  
Ye.V. Paltov ◽  
Z.Z. Masna ◽  
I.V. Chelpanova
Keyword(s):  
Mucous Membrane ◽  
Scientific Literature ◽  
Opioid Analgesic ◽  
Morphometric Parameters ◽  
Morphometric Characteristics ◽  
Prolonged Administration ◽  
Laryngeal Mucosa ◽  
Opioid Drugs ◽  
Conventional Methods ◽  
Sexually Mature

Background. The problem of uncontrolled use of opioid drugs is extremely relevant based on the data of domestic and world statistics which are covered in the scientific literature. That is why the study of indicators of morphometric characteristics of the laryngeal mucosa under opioid exposure under experimental opioid exposure will be of interest to both morphologists and practical otorhinolaryngologists. Objective: To study the morphometric parameters of the laryngeal mucosa in normal at different times of the experimental opioid effect and its cancellation. Methods. The material of the study were sexually mature, outbred rats - males in the amount of 61 animals, weighing 80 - 135 g, aged 4.5 - 7.5 months. Histological specimens were prepared according to conventional methods. All morphometric studies were performed using primary (unedited) photographs taken on a Meiji MT4300 LE microscope, Canon EOS 550D x100 lens. All statistical calculations were performed using RStudio v. 1.2.5042. Results. Throughout the experiment, the change of morphometric parameters of the laryngeal mucosa with signs of wavy growth and decline was clearly observed at all times. More positive was the dynamics of morphometric parameters after the abolition of the opioid analgesic, which hypothetically suggests the process of recovery of the mucosa, even after prolonged administration of the opioid.

Mucous membrane pemphigoid: nasal and laryngeal manifestations

2003 ◽  
Vol 117 (11) ◽  
pp. 885-888 ◽  
Author(s):  
O. J. H. Whiteside ◽  
P. Martinez Devesa ◽  
I. Ali ◽  
J. W. R. Capper
Keyword(s):  
Mucous Membrane ◽  
Scar Tissue ◽  
Mucous Membrane Pemphigoid ◽  
Mucosal Surfaces ◽  
Laryngeal Mucosa ◽  
Diagnostic Role ◽  
Blistering Disease ◽  
Low Threshold ◽  
Laser Excision ◽  
Prompt Action

Mucous membrane pemphigoid (MMP) is a sub-epithelial blistering disease that primarily involves mucosal surfaces but may also involve the skin. Clinically, it appears as vesiculobullous lesions of the oral cavity and eyes, but other tissues such as the nasopharyngeal and laryngeal mucosa can also be affected. Ultimately, scarring and airway stenosis may occur. The condition should be managed by a multidisciplinary team led by a dermatologist. Immunosuppressive therapy forms the mainstay of treatment, with surgery having both a diagnostic role and a use in the treatment of complications such as airway obstruction. There must be a low threshold of suspicion for laryngeal involvement in this group of patients, so that prompt action can be taken. Once laryngeal stenosis has occurred repeated endoscopic laser excision of scar tissue can be used to maintain an adequate airway. Adjuvant use of mitomycin-C can be used beneficially in the treatment of laryngeal complications of MMP.

A Fundamental Study of an Animation Presentation System for JSL Signs

1993 ◽  
Vol 5 (6) ◽  
pp. 594-600
Author(s):  
Mina Terauchi ◽  
◽  
Yuji Nagashima ◽  
Kazuyuki Kanda ◽  
Takateru Nishimura ◽  
...  
Keyword(s):  
Rigid Body ◽  
Sign Language ◽  
Object Oriented ◽  
Rigid Bodies ◽  
Hearing Impaired ◽  
Fundamental Study ◽  
Key Frame ◽  
Joint Structure ◽  
The Future ◽  
Frame Method

We describe a system of presenting the animation of the Japanese Signs by a Key-Frame Method as part of a supporting system for hearing-impaired persons. According to this system, JSL Signs are extracted from Japanese sentences whose elemental forms have been analyzed, and sign language corresponding to each sign is presented in image by using the angle displacement of each joint as a parameter. As a result of obtaining animated sign presentations by using several sample sentences, it was possible to recognize signs. However, since presented images are skelton models, it will be required in the future to examine a more effective image presentation system for the cases in which more realistic models are presented. In addition, in order to solve various problems associated with Key-Frame Method, we also examined an animated presentation system with the concept of Object-Oriented introduced. Taking note of the fact that a human is a multi-joint structure, we define a descriptive form in which the movement of each rigid body and the positional relationship between rigid bodies are treated as knowledge. By so doing, it now becomes possible to provides more flexible descrive forms and motion expressions.

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