scholarly journals Radiation-Induced Meningioma Following Radiotherapy for Pituitary Adenonoma: A Case Report

2013 ◽  
Vol 12 (1) ◽  
Author(s):  
Dr Ellyda Muhammed Nordin

It is well known that ionizing radiation has an onco-genetic activity and has been implicated in the causation of brain tumors. However, when a new growth appears adjacent to the site of previous tumor, the diagnosis is more toward recurrence. In addition to that, the possible cause might be overlooked, when it occurs many years after radiation treatment. We report a case of radiation-induced meningioma developed 20 years after the patient received radiotherapy for pituitary adenoma.

2012 ◽  
Vol 01 (01) ◽  
pp. 078-079
Author(s):  
Sachin Borkar ◽  
Deepak Agrawal

Abstract Although exposure to high dose ionizing radiation (following therapeutic radiotherapy) has been incriminated in the pathogenesis of many brain tumors, exposure to chronic low dose ionizing radiation has not yet been shown to be associated with tumorigenesis. The authors report a case of a 50-year-old atomic reactor scientist who received a cumulative dose of 78.9 mSv over a 10-year period and was detected to have an acoustic neuroma another 15 years later. Although there is no proof that exposure to ionizing radiation was the cause for the development of the acoustic neuroma, this case highlights the need for extended follow-up periods following exposure to low dose ionizing radiation.


Neurosurgery ◽  
1990 ◽  
Vol 26 (2) ◽  
pp. 329-331 ◽  
Author(s):  
Michael D. Partington ◽  
Dudley H. Davis

Abstract Radiation-induced meningiomas are becoming increasingly well-recognized. We report a case of a 35-year-old man who developed a suprasellar meningioma 9 years after receiving a radiation dose of 4480 cGy for a pituitary adenoma. The literature is also reviewed.


2021 ◽  
Vol 5 (9) ◽  
pp. CR1-CR4
Author(s):  
Sam Ponraj Davidson. S ◽  
Somasundaram Elangovan ◽  
Suman Jhansi Lakshmi ◽  
B. Senthil Kumar

Osteonecrosis was first described as a consequence of ionizing radiation used in the treatment of malignant tumors but later a variety of causes for osteonecrosis were found which include, Medication induced, radiation induced, chemical induced and infection induced. Terms such as: bisphosphonate osteonecrosis (BON), Bisphosphonate Associated Osteonecrosis of the Jaws (BONJ), Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ), Antiresorptive Osteonecrosis of the Jaw (ARONJ) and Medication Related Osteonecrosis of the Jaw (MRONJ) have all had proponents and all continue to be utilized. However, Migliorati  first proposed a designation of the disease as osteochemonecrosis. This case report is about a chemical induced osteonecrosis patient who placed rat poison inside the mouth. 


2021 ◽  
Vol 12 ◽  
Author(s):  
Jinci Lu ◽  
Liam Chen

Pituitary sarcoma arising in association with pituitary adenoma is an uncommon finding. Most cases of secondary sarcoma have been noted to arise with a median interval of 10.5 years post radiation. In this case report, we describe a 77-year-old man with an incidental discovery of a pituitary macroadenoma on magnetic resonance imaging (MRI) and underwent radiotherapy. Three years after radiation treatment, there was an acute change in clinical symptoms and increase in tumor size and mass effect on the optic chiasm which prompted surgical resection. A pituitary adenoma along with a separate spindle-cell sarcomatous component was identified in histology. Immunohistochemical stain for muscle markers confirmed a development of pituitary rhabdomyosarcoma (RMS). Molecular profiling of the tumor identified mutations in TP53, ATRX, LZTR1, and NF1. Despite its rarity, characterization of pituitary RMS with immunohistochemistry and molecular studies may provide an insight to its pathophysiological relationship with pituitary adenoma.


2008 ◽  
Vol 93 (2) ◽  
pp. 263-267 ◽  
Author(s):  
Thomas B. Daniels ◽  
Bruce E. Pollock ◽  
Robert C. Miller ◽  
Claudia F. Lucchinetti ◽  
Jacqueline A. Leavitt ◽  
...  

2019 ◽  
Vol 105 (6) ◽  
pp. NP4-NP7
Author(s):  
Laurien De Roeck ◽  
Sandra Nuyts

Introduction: The most important long-term effect of radiotherapy is induction of secondary cancers. A rare radiation-induced tumor is a squamous cell carcinoma of the external auditory canal. Case reports have been described in Asian patients after radiotherapy for nasopharyngeal cancer. Case description: We describe an unusual case report of a 53-year-old Caucasian man who developed squamous cell carcinomas of the right and left external auditory canal, respectively 29 and 30 years after radiotherapy for a pituitary adenoma. Conclusion: In young patients with benign tumors, we should always evaluate whether the benefits of radiotherapy outweigh the risks and side effects. After radiotherapy, screening programs should be developed since early detection improves salvage treatment of these secondary and often morbid tumors.


2016 ◽  
Vol 15 (2) ◽  
pp. 215-217 ◽  
Author(s):  
Ami Patel-Yadav ◽  
Anurag Singh

AbstractBackgroundSuccess with acupuncture-like transcutaneous nerve stimulation (ALTENS) in the treatment of radiation-induced xerostomia has not been reported after an extended time.MethodsWe report a case of successful ALTENS therapy 5 years after radiation treatment.ResultsThe patient discontinued treatments in a second course due to complete resolution of symptoms.ConclusionThis case report demonstrates a potential for offering ALTENS to those long suffering from radiation-induced xerostomia.


Author(s):  
M. L. Knotek

Modern surface analysis is based largely upon the use of ionizing radiation to probe the electronic and atomic structure of the surfaces physical and chemical makeup. In many of these studies the ionizing radiation used as the primary probe is found to induce changes in the structure and makeup of the surface, especially when electrons are employed. A number of techniques employ the phenomenon of radiation induced desorption as a means of probing the nature of the surface bond. These include Electron- and Photon-Stimulated Desorption (ESD and PSD) which measure desorbed ionic and neutral species as they leave the surface after the surface has been excited by some incident ionizing particle. There has recently been a great deal of activity in determining the relationship between the nature of chemical bonding and its susceptibility to radiation damage.


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