scholarly journals Prevalence of Osteoporosis and Risk of Developing Fragility Fracture in Post-Menopausal Women

2018 ◽  
Vol 17 (1) ◽  
Author(s):  
Muhammad Hafiz Bin Hamzah ◽  
Aminudin Che Ahmad

Introduction: Osteoporosis and fragility fracture pose major health concern and cause significant financial burdens in healthcare system. The objectives of this study were to determine the prevalence of osteoporosis among post-menopausal women and to predict the risk of having the major osteoporotic and hip fracture in 10 years using the WHO Fracture Risk Assessment Tool. Materials and Methods: This was a cross-sectional study spanning over a two-year period (from June 2015 to June 2017) investigating post-menopausal women who did their Bone Mass Density (BMD) test at Hospital Melaka. Collected BMD data and parameters were used for analysif of the prevalence of osteoporosis among the study population and FRAX calculation was used to predict the average risk of fragility fracture in 10 years. Statistical analysis was done using SPSS statistical package. Results: Prevalence of osteoporosis among 388 post-menopausal women age 45 to 90 years old was 29.9%. More than half of patients had osteoporosis were Chinese (51%) followed by Malay (43%), Indian (5%) and others (1%). The 10 years average percentage of developing major osteoporosis was 10.81 ± 9.55 %, while the average percentage of developing hip fracture was 4.20 ± 6.53. Conclusion: Prevalence of the post-menopausal women who were osteoporotic was about 30% which is comparable to other countries (Japan, Egypt, Australia, Mexico, Argentina and India). The 10 years average percentage of developing major osteoporosis and hip fracture in our study is quite high, approximately around 20% and 10%, respectively.

Author(s):  
SUNIL SHASHIKANT BORKAR BORKAR

BACKGROUND: Increasing prevalence of osteoporosis and osteopenia in the Indian population is a major community health concern in future. Camp based screening of low bone mineral density (BMD) by using calcaneum quantitative ultrasound scan (QUS) is widely used low cost procedure in India. Hence Calcaneum QUS was used to determine the prevalence of osteoporosis and osteopenia in rural population of Gurukunj Ashram, Dist Amravati (Maharashtra) in present camp based study. METHODS: In present study total 99 participants aged 25-65 years were included.  Each participant was enquired for their demographic details, dietary habit, lifestyle pattern, exercise and menstrual history related information in prescribed format and assessed for BMD (as T score) by using calcaneum QUS. The data were express in percentages and proportions and results were expressed as descriptive statistics. Chi square test was used to compare the risk factors for categorical variables. RESULTS:  Out of total participants (n=99), 66.66% (n = 66) were female subjects and 33.3% (n = 33) were male. As per the WHO criteria of BMD, 34.34 % participants were osteoporotic, 56.56% were osteopenic, whereas approximately 9.09% had normal bone density. A significant association (χ2 = 38.50, P < 0.00001) was reported between the T‑score and different age groups. Study shows apparent increasing trend in the frequency of osteopenic and osteoporotic participants with age of 35 and 56 years onward respectively. CONCLUSIONS: Present camp based reports the high prevalence of low bone mass density in increasing age in rural population. 


2018 ◽  
Vol 11 ◽  
pp. 117954411775405 ◽  
Author(s):  
J Renwick Beattie ◽  
Diane Feskanich ◽  
M Clare Caraher ◽  
Mark R Towler

Studies have shown that Raman spectroscopic analysis of fingernail clippings can help differentiate between post-menopausal women who have and who have not suffered a fracture. However, all studies to date have been retrospective in nature, comparing the proteins in nails sourced from women, post-fracture. The objective of this study was to investigate the potential of a prospective test for hip fracture based on spectroscopic analysis of nail tissue. Archived toenail samples from post-menopausal women aged 50 to 63 years in the Nurses’ Health Study were obtained and analysed by Raman spectroscopy. Nails were matched case-controls sourced from 161 women; 82 who underwent a hip fracture up to 20 years after nail collection and 81 age-matched controls. A number of clinical risk factors (CRFs) from the Fracture Risk Assessment (FRAX) tool had been assessed at toenail collection. Using 80% of the spectra, models were developed for increasing time periods between nail collection and fracture. Scores were calculated from these models for the other 20% of the sample and the ability of the score to predict hip fracture was tested in model with and without the CRFs by comparing the odds ratios (ORs) per 1 SD increase in standardised predictive values. The Raman score successfully distinguished between hip fracture cases and controls. With only the score as a predictor, a statistically significant OR of 2.2 (95% confidence interval [CI]: 1.5-3.1) was found for hip fracture for up to 20 years after collection. The OR increased to 3.8 (2.6-5.4) when the CRFs were added to the model. For fractures limited to 13 years after collection, the OR was 6.3 (3.0-13.1) for the score alone. The test based on Raman spectroscopy has potential for identifying individuals who may suffer hip fractures several years in advance. Higher powered studies are required to evaluate the predictive capability of this test.


2009 ◽  
Vol 16 (03) ◽  
pp. 424-427
Author(s):  
IRSHAD UL HAQ ◽  
ZAHID MASOOD

Objectives: To Study the prevalence of osteoporosis among post menopausal women in the Faisalabad city and comparethat with other developed and developing countries. S t u d y Design: A Cross Sectional Study. Place and Duration of Study: Medina TeachingHospital Faisalabad and Al Bari Hospital Faisalabad from February 2008 to April 2008. Patients and Methods: A total of 300 post menopausalwomen were included after valid consent and observing inclusion and exclusion criteria. Quantitative Ultrasound Device (QUO) that is BMDwas assessed from the heel of each participant. T-Scores were obtained and WHO classification was followed. A scale was used to assessthe Body Mass Index measuring height and weight. Data collection sheet having structured questions was used for checklist for obtainingpertinent information. Results: Out of 300 post menopausal women overall prevalence of Osteoporosis (OP) was 20%. Further, 44% wereOsteopenic. Results were comparable with other countries as well. Conclusion: Osteoporosis (OP) is not uncommon in our country. It shouldbe considered as a Public Health Problem. Early screening and prompt treatment can prevent the heavy cost on fracture managements. InPakistan, even in Asia Key data is not available to convince Policy makers that OP is a serious burden on population and to invest in preventionis the better option. Health Education is imperative for target population.


2018 ◽  
Vol 9 (3) ◽  
pp. 117
Author(s):  
SanjayKumar Rai ◽  
Omna Shaki ◽  
Manoj Kashid ◽  
BarunK Chakrabarty

2016 ◽  
Vol 53 (2) ◽  
pp. 219
Author(s):  
Shazia Husain ◽  
Vibha Bhatnagar

Osteoporosis and cardiovascular disease (CVD) are a major growing public health problem with impact that crosses medical, social and economic lines. The aim of this study was to assess the prevalence and risk of osteoporosis and CVD in post menopausal women. A cross sectional study was conducted on 322 post menopausal women aged 45-55 years residing in Udaipur city, Rajasthan. Risk of osteoporosis in subjects was assessed using Osteoporosis Self Assessment Tool for Asian (OSTA) and risk of CVD was determined using CVD risk assessment tool. The body weight and age of subjects were calculated for the OSTA index sore. Total cholesterol, high density lipoprotein, diastolic blood pressure and smoking habits of subjects were assessed for CVD risk score. Results of OSTA assessment revealed that 24.22 % respondents were at medium risk of osteoporosis whereas results of CVD assessment showed that a large number of subjects i.e. 82.91 % were at medium risk of CVD. Combining both the assessment scores of subjects, 23.91 % post menopausal women were found at medium risk of both osteoporosis and CVD. Study showed a lower prevalence of osteoporosis having medium risk and higher prevalence of CVD having moderate risk in post menopausal women. The findings suggest that more studies should be done on these at risk population for preventive and therapeutic interventions.


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