Screening For Osteoporosis And Osteopenia In Rural Population Using Calcaneum QUS – A Camp Based Study

2020 ◽  
Vol 8 (02) ◽  
Author(s):  
SUNIL SHASHIKANT BORKAR BORKAR
Keyword(s):  
Rural Population ◽  
Mass Density ◽  
Age Groups ◽  
Health Concern ◽  
Categorical Variables ◽  
Bone Mass Density ◽  
Dietary Habit ◽  
Mineral Density ◽  
T Score ◽  
Prevalence Of Osteoporosis

BACKGROUND: Increasing prevalence of osteoporosis and osteopenia in the Indian population is a major community health concern in future. Camp based screening of low bone mineral density (BMD) by using calcaneum quantitative ultrasound scan (QUS) is widely used low cost procedure in India. Hence Calcaneum QUS was used to determine the prevalence of osteoporosis and osteopenia in rural population of Gurukunj Ashram, Dist Amravati (Maharashtra) in present camp based study. METHODS: In present study total 99 participants aged 25-65 years were included.  Each participant was enquired for their demographic details, dietary habit, lifestyle pattern, exercise and menstrual history related information in prescribed format and assessed for BMD (as T score) by using calcaneum QUS. The data were express in percentages and proportions and results were expressed as descriptive statistics. Chi square test was used to compare the risk factors for categorical variables. RESULTS:  Out of total participants (n=99), 66.66% (n = 66) were female subjects and 33.3% (n = 33) were male. As per the WHO criteria of BMD, 34.34 % participants were osteoporotic, 56.56% were osteopenic, whereas approximately 9.09% had normal bone density. A significant association (χ2 = 38.50, P < 0.00001) was reported between the T‑score and different age groups. Study shows apparent increasing trend in the frequency of osteopenic and osteoporotic participants with age of 35 and 56 years onward respectively. CONCLUSIONS: Present camp based reports the high prevalence of low bone mass density in increasing age in rural population. 

scholarly journals Image Analysis of Periapical Radiograph for Bone Mineral Density Prediction

2018 ◽  
Vol 8 (4) ◽  
pp. 2083 ◽  
Author(s):  
Rini Widyaningrum ◽  
Sri Lestari ◽  
Ferry Jie
Keyword(s):  
Bone Mineral Density ◽  
Image Analysis ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Negative Correlation ◽  
Mass Density ◽  
The Body ◽  
Bone Mass Density ◽  
Mineral Density ◽  
T Score

<span>Osteoporosis is a systemic skeletal disease. Parameter from any bone site in the body has possibility to be developed as a predictor of osteoporosis. The alteration in the mandible trabecular bone is visible in periapical radiographs. The aim of this study was to correlate the area parameter and the integrated density of periapical radiograph with bone mineral density. Image analysis of periapical radiograph i.e. measurement of area parameter and integrated density was done on Region of Interest (ROI) by using canny edge detection method. Result of this study showed that the area parameter has asignificant (α&lt;0.05) negative correlation with the bone mass density (BMD) of the lumbar spine (r = -0.371) and T-score of the lumbar spine (r = -0.383). The linear regression test showed that the area parameter only can be used to predict T-score of the lumbar spine (F=5.822, α&lt;0.05). The integrated density showed a significant (α &lt; 0.05) negative correlation with T-score of hip (r = -0.332) and T-score of lumbar spine (r = -0.377). It can be concluded that the area parameter can be used as one of input parameters for computer-aided system of osteoporosis early detection by using periapical radiograph.</span>

scholarly journals Association Between Urinary Triclosan With Bone Mass Density and Osteoporosis in US Adult Women, 2005‒2010

2019 ◽  
Vol 104 (10) ◽  
pp. 4531-4538 ◽  
Author(s):  
Shaofang Cai ◽  
Jiahao Zhu ◽  
Lingling Sun ◽  
Chunhong Fan ◽  
Yaohong Zhong ◽  
...  
Keyword(s):  
Mass Density ◽  
Premenopausal Women ◽  
Bone Mass Density ◽  
Adult Women ◽  
Laboratory Studies ◽  
Mineral Density ◽  
Health And Nutrition ◽  
Collagen Accumulation ◽  
The Relationship ◽  
Prevalence Of Osteoporosis

Abstract Context Laboratory studies have demonstrated that triclosan (TCS) can cause significant interstitial collagen accumulation and an increase in trabecular bone. However, little is known about the relationship between TCS exposure and human bone health. Methods We used 2005 to 2010 National Health and Nutrition Examination Survey data to examine the association between urinary TCS concentration and bone mineral density (BMD) and osteoporosis in US adult women aged ≥20 years. After inclusion and exclusion, 1848 women were analyzed. Results After adjustment for other covariates, we observed significant associations between tertile 3 of TCS concentration and lower BMD in regions of the total femur (β = −0.016; 95% CI = −0.032, −0.000), intertrochanteric region (β = −0.022; 95% CI = −0.042, −0.002), and lumbar spine (β = −0.014; 95% CI = −0.029, 0.001), respectively, relative to tertile 1. Compared with women at tertile 1, those at tertile 3 were more likely to have increased prevalence of osteoporosis in the intertrochanteric region (OR = 2.464; 95% CI = 1.190, 5.105). Conclusion This epidemiological study investigated the association between urinary TCS concentration and BMD and osteoporosis in US adult women. We found urinary TCS concentration was negatively associated with BMD and was positively associated with the prevalence of osteoporosis. The evidence was stronger in postmenopausal women than in premenopausal women. Future prospective studies are needed to validate these findings.

scholarly journals Study of prevalence of osteoporosis in males of above 40 years age group attending SMS Hospital, Jaipur

2017 ◽  
Vol 3 (4) ◽  
pp. 837
Author(s):  
Parwez Qureshi ◽  
R. C. Meena ◽  
Jakir Husain ◽  
Gaurav Deshwar ◽  
Vineet Maheshwari ◽  
...  
Keyword(s):  
Vitamin D ◽  
Dietary Habits ◽  
Good Control ◽  
Age Group ◽  
Mineral Density ◽  
Cross Sectional ◽  
T Score ◽  
Vitamin D Levels ◽  
Study Population ◽  
Prevalence Of Osteoporosis

<p class="abstract"><strong>Background:</strong> Whenever osteoporosis is discussed, the focus is on women; men are far less likely to receive a diagnosis of osteoporosis or osteoporotic fracture because of considerable gaps in knowledge on male osteoporosis. The aim and objectives were to study the prevalence of osteoporosis in males of above 40 year age group attending SMS Hospital Jaipur &amp; to explore the influence of various modifiable and non-modifiable risk factors on BMD.</p><p class="abstract"><strong>Methods:</strong> Study Location: SMS Medical College and Hospital, Jaipur. Study design: Hospital based cross sectional study. Study period: April 2015 to December 2016. Sample Size: 200. Work up: After taking ethical clearance and informed verbal consent, demographic and clinical details were noted along with S- calcium, Vitamin D and bone mineral density assessment. Osteoporosis was defined as T score ≤−2.5 bone mass −1 to −2.5 and normal as &gt;−1. Data thus collected was analysed with help of SPSS 22.0 through frequency, percentages, Mean, SD and ANOVA.<strong></strong></p><p class="abstract"><strong>Results:</strong> Prevalence of osteopenia and osteoporosis in the study population was 28.5% and 11.5%. Age wise maximum prevalence was in the age group 71-80 years (31.81%). Prevalence of osteoporosis was more among Muslim community 20.83%, more in low socio economic group (BPL). T score of study population was -0.3705±1.41. The mean BMI, S-Calcium, Vitamin D levels and T score values among osteopenic and osteoporotic patients were statistically highly significant when compared to patients without osteo-penic/porotic changes (p&lt;0.05).</p><p><strong>Conclusions:</strong> Osteoporosis is a silent killer and prevention is better than cure as prevention requires simple steps such as good dietary habits, active life style, good control of systemic disorders, reduced intake of tobacco and alcohol.</p>

scholarly journals P1621VITAMIN D SUPPLEMENTATION: CHANGES IN BONE MINERAL DENSITY IN KIDNEY TRANSPLANT PATIENTS WITH LONG TERM DURATION OF THE GRAFT

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Yuri Battaglia ◽  
Michele Provenzano ◽  
Francesco Tondolo ◽  
Antonio Bellasi ◽  
Pasquale Esposito ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Kidney Transplant ◽  
Bone Mineral ◽  
Categorical Variables ◽  
Z Score ◽  
Mineral Density ◽  
T Score

Abstract Background and Aims In the medical literature, several studies have linked bone mineral density (BMD) with vitamin D deficiency in kidney transplant patients (KTRs). However, in spite of the fact that ergocalciferol, cholecalciferol and calcifediol reduce parathyroid hormone (PTH) and improves calcium levels, their effects on the bone mineral density (BMD) in KTRs remain undefined. In consideration of the lack of data available, we aim at investigating the effect of inactive form of vitamin D supplementation on the BMD over a follow-up period up to 2 year, in a real-life cohort of long-term kidney transplant(KT). Method This study was carried out in KTRs who were followed up in a Nephrology Unit. Exclusion criteria were parathyroidectomy, therapy with bisphosphonate, previous history of bone fractures. Demographic, clinical and immunosuppressive agents were collected. Based on 25-OH-D levels, KTRs were classified as suffering from deficiency (&lt; 30 ng/mL). BMD was evaluated at lumbar vertebral bodies (LV) and right femoral hip (FH) by a single operator, using a standard dual energy X-ray absorptiometry. According to WHO criteria, results were expressed as T-score (standard deviation [SD] relative to young healthy adults), and Z-score (SD relative to age-matched controls). Osteoporosis and osteopenia were defined as T score ≤ −2.5 SD and T score &lt; −1 and &gt; −2.5 SD, respectively. Laboratory data, 25-OH-D, and BMD were measured at baseline and after 24 months of supplementation therapy. Vitamin D deficiency was corrected using standard treatment strategy recommended for general population. Continuous variables were expressed as mean ± SD whereas categorical variables as percentage. The Student’s t test and chi-square test were used to compare to compare continuous and categorical variables, respectively. For before and after comparisons of continuous variables, the paired t-test or one-sample Wilcoxon signed rank test were used based on variable’s distribution. Results Data pertaining to 111 out of 133 consecutive outpatients were collected, of whom most were males (69.4%), no-smokers (89.1%) and treated with glucocorticoids (84%). The mean age was 53.9±11.6 years and months after transplant was 161.6±128.3. No statistical differences were found among patients with normal BMD, osteopenia or osteoporosis at LV and FH in terms of age at transplant, gender distribution, time on dialysis, BMI and eGFR, serum calcium, serum phosphate, 25-OH-D and iPTH. At baseline, 25-OH-D was 13.9±7.2 ng/ml and the prevalence of osteopenia/osteoporosis was 40.9% (T-Score -1.69±0.37; Z-score -1.16±1.09) and 21.8 % (T-Score -3.15±0.50; Z-score -2.27±0.58) at LV; 55.3 % (T-Score -1.8±0.46; Z-score -0.84±0.633) and 14 % (T-Score -2.83±0.39; Z-score -1.65±0.49) at FH. After 27.6±3.7 months of therapy with cholecalciferol at mean dose of 13.396±7.537 UI at week, 25-OH-D values increased to 29.4±9.4 ng/ml (p&lt;0.0001) while no statistically significant changes were found in Z-score and T-score at both sites, except for a mild improvement in lumbar vertebral Z-score, reaching −0.82± 0.7 (p = 0.06) in KTRs with osteopenia Conclusion Our study showed BMD remained stable after up to 2 years of inactive vitamin D therapy in long-term kidney transplant with vitamin D deficiency. A mild increase in Z-score was observed in the L-spine. Further designated studies should be conducted to demonstrate the effect of vitamin D on BMD.

scholarly journals Autoimmunological serum parameters and bone mass density in premature ovarian insufficiency: a retrospective cohort study

2020 ◽  
Author(s):  
Klara Beitl ◽  
Klara Rosta ◽  
Nina Poetsch ◽  
Manuel Seifried ◽  
Daniel Mayrhofer ◽  
...  
Keyword(s):  
Bone Mass ◽  
Retrospective Cohort ◽  
Mass Density ◽  
Dual Energy ◽  
Premature Ovarian Insufficiency ◽  
Bone Mass Density ◽  
Ovarian Insufficiency ◽  
X Ray ◽  
T Score ◽  
Normal Women

Abstract Purpose It is still not clear whether to screen women with primary premature ovarian insufficiency for autoimmunity. Moreover, a possible association of autoimmunity with decreased bone mass density in premature ovarian insufficiency patients has not been evaluated. Thus, the objectives of this study were to review our experience with the use of an autoimmune screening panel in premature ovarian insufficiency women and to focus on bone mass density. Methods In a retrospective cohort study, 76 chromosomally normal women with primary premature ovarian insufficiency were included. The main outcome parameters were the results of an autoimmune screening panel and of dual-energy X-ray absorptiometry. Results Median age was 33 years. Sixty percent of premature ovarian insufficiency patients revealed abnormal dual-energy X-ray absorptiometry results (minimal T-score < −1.0). Any signs of autoimmunity were found in 21 women (36.2%). The most frequent abnormal results were increased thyroperoxidase antibodies (24.1%) and thyroglobulin antibodies (20.7%). A longer duration of amenorrhea (β = −0.015; p = 0.007), any abnormality during autoimmune screening (β = −0.940; p = 0.010), and a lower body mass index (β = −0.057; p = 0.036) were associated with a lower minimal T-score. Conclusion In chromosomally normal women with primary premature ovarian insufficiency, the prevalence of autoimmunity and decreased bone mass density seem high. Our data highlight the association between autoimmune abnormalities and decreased dual-energy X-ray absorptiometry results.

scholarly journals Aging and Bone Health in Individuals with Developmental Disabilities

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Joan Jasien ◽  
Caitlin M. Daimon ◽  
Stuart Maudsley ◽  
Bruce K. Shapiro ◽  
Bronwen Martin
Keyword(s):  
Developmental Disabilities ◽  
Bone Health ◽  
Mass Density ◽  
Health Concern ◽  
Bone Mass Density ◽  
Low Bone Mass ◽  
Comprehensive Overview ◽  
Men And Women ◽  
Age Related ◽  
Caucasian Women

Low bone mass density (BMD), a classical age-related health issue and a known health concern for fair skinned, thin, postmenopausal Caucasian women, is found to be common among individuals with developmental/intellectual disabilities (D/IDs). It is the consensus that BMD is decreased in both men and women with D/ID. Maintaining good bone health is important for this population as fractures could potentially go undetected in nonverbal individuals, leading to increased morbidity and a further loss of independence. This paper provides a comprehensive overview of bone health of adults with D/ID, their risk of fractures, and how this compares to the general aging population. We will specifically focus on the bone health of two common developmental disabilities, Down syndrome (DS) and cerebral palsy (CP), and will discuss BMD and fracture rates in these complex populations. Gaining a greater understanding of how bone health is affected in individuals with D/ID could lead to better customized treatments for these specific populations.

scholarly journals KORELASI KADAR CRP, TNF-α DAN BONE MINERAL DENSITY DENGAN CARBOXYTERMINAL CROSSLINKED TELOPEPTIDE TYPE I OF COLLAGEN DI PENDERITA ARTRITIS REUMATOID

2018 ◽  
Vol 18 (2) ◽  
pp. 77
Author(s):  
Kusworini Handono ◽  
BP Putra Suryana ◽  
Sulistyorini Sulistyorini
Keyword(s):  
Bone Mineral Density ◽  
Bone Resorption ◽  
Bone Mass ◽  
Bone Mineral ◽  
Mass Density ◽  
Bone Mass Density ◽  
Bone Resorption Marker ◽  
Type I ◽  
Mineral Density ◽  
Tnf Α

Rheumatoid Arthritis (RA) is a systemic autoimmune disease accompanied by decreasing bone mass density and ultimately leads toosteoporosis. The cause of decreased bone mass density is still unknown, but the inflammation has been suspected as an important factor.The correlation between the severity of inflammation with the decrease in bone mass density in Indonesian RA patients has not been muchstudied. The purpose of this study was to know the assessment in the correlation between levels of C-reactive protein (CRP), Tumour NecrosisFactor-α (TNFα) and bone mineral density (BMD) with bone resorption marker CTx-1 β-Cross Laps in premenopausal RA patients.Thisobservational study using cross sectional design, was carried out in the Rheumatology Clinic and Central Laboratory of RSSA, Malang fromAugust 2009 until October 2010. All 47 RA patients were diagnosed according to revised of the 1997 American College of Rheumatology(ACR). Measurement of CRP levels uses turbidimetry method, TNF-α and CTX-1 β-Cross Laps levels using ELISA methods and the measurementof BMD using DEXA. The results of this study showed mean levels of CRP were 4.288±1.775 g/L, TNF-α were 322.077±275.248 pg/mLand CTX-1 β-Cross Laps were 0.588±0.139 ng mL. The correlation of CRP and TNF-α levels with CTX-1 β-Cross Laps level were r=0.5832,p=0.453 and r=0.615, p=0.041. Correlation of CTX-1 β-Cross Laps level and Femoral Neck BMD was r=–0.469, p=0.143 and r=0.248,p=0.799 for L average BMD. There was no correlation between CRP level and BMD results with bone resorption marker CTX-1 β-Cross Laps,but there is a significant correlation between high levels of TNFα with CTX-1 β-Cross Laps. It seems that TNF-α appears to be contributed tothe decrease of bone mass density in RA patients.

scholarly journals Low Bone Mineral Density and Calcium Levels as Risks for Mortality in Patients with Self-Discontinuation of Anti-Osteoporosis Medication

2021 ◽  
Vol 19 (1) ◽  
pp. 197
Author(s):  
Chun-Sheng Hsu ◽  
Shin-Tsu Chang ◽  
Yuan-Yang Cheng ◽  
Hsu-Tung Lee ◽  
Chih-Hui Chen ◽  
...  
Keyword(s):  
Lumbar Spine ◽  
Femoral Neck ◽  
Mortality Risk ◽  
Calcium Level ◽  
Cox Regression ◽  
Mass Density ◽  
Bone Mass Density ◽  
Mineral Density ◽  
Osteoporosis Medication ◽  
The Right

Bone mass density (BMD) has been used universally in osteoporosis diagnosis and management. Adherence to anti-osteoporosis medication is related to mortality risk. This study aimed to investigate the relationship between mortality and low BMD of the femoral neck and vertebra among patients self-discontinuing anti-osteoporosis medication. Between June 2016 and June 2018, this single-center retrospective study recruited 596 participants who self-discontinued anti-osteoporosis medication. Patients were categorized into four groups by BMD of the right femoral neck and lumbar spine. Occurrence and causes of mortality were obtained from medical records. Independent risk factors and the five-year survival of various levels of BMD were analyzed by Cox regression and the Kaplan–Meier survival analysis. BMD value and serum calcium level were significantly lower in the mortality group (p < 0.001). Compared to the reference, the adjusted hazard ratio (HR) for all-cause mortality in patients with lower BMD of both the lumbar spine and femoral neck was 3.03. The five-year cumulative survival rate was also significantly lower (25.2%, p < 0.001). A low calcium level was also associated with mortality (HR: 0.87, 95% CI: 0.76–0.99, p = 0.033). In conclusion, lower BMD and calcium levels were associated with higher mortality risk in patients with poor adherence. Hence, patients self-discontinuing anti-osteoporosis medication should be managed accordingly.

scholarly journals Enzyme-inducing antiseizure drugs associate with low bone mineral density in men with epilepsy

2021 ◽  
Author(s):  
Aline de Fátima Dias ◽  
Lucas Scárdua Silva ◽  
Rafael Batista João ◽  
Amanda Canal Rigotti ◽  
Gabriel Ferri Baltazar ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Age Of Onset ◽  
Young Group ◽  
Categorical Variables ◽  
Mineral Density ◽  
Chi Square ◽  
T Score ◽  
Age Range ◽  
The Impact

Introduction: Little is known about the impact of enzyme-inducing antiseizure drugs (EI-ASD) on the reduction of Bone Mineral Density (BMD) in men with epilepsy (MWE). Objectives: To evaluate the BMD in MWE exposed to EI-ASDs (phenytoin, carbamazepine and phenobarbital) and its relationship with the duration of epilepsy. Methods: We evaluated BMD from 74 consecutive MWE (median age (range), 52.5 (25- 74) years) exposed to previous or current EI-ASDs, followed at UNICAMP-Brazil. Individuals were split into two groups (young-group, 31 individuals [25-49 years]; older group, 43 subjects, [50-74 years]). The BMD test evaluated t-score indexes from the femoral neck, whole femur and lumbar spine. Osteopenia was defined with t-score of - 1.0 to -2.4; osteoporosis, with T-scores lower than -2.5. Data were extracted from medical records. We analyzed data with SPSS22, performed chi-square tests for categorical variables and applied a partial correlation test (controlled for age) between BD scores and duration of epilepsy. Results: BMD was reduced in 49/74 men (66.2%). Both groups presented equivalent proportions of BMD abnormalities (p=0.087) (young-group [14/41 normal (45%), 12/31 osteopenia (39%), 5/31 osteoporosis (16%)]; older-group [11/43 normal (26%), 16/43 osteopenia (37%), 16/43 osteoporosis (37%)]. BMD did not correlate with the duration of disease or age of onset. Conclusion: BMD reduction is highly prevalent in MWE exposed to EI-ASD, including young individuals. Data suggest that exposure to EI-ASD may associate with early BMD reduction, which evolve to osteopenia and osteoporosis. BMD evaluation in MWE and appropriate treatment may be necessary to reduce fractures’ risk.

scholarly journals Densitas Massa Tulang pada Pasien HIV/AIDS

2017 ◽  
Vol 3 (4) ◽  
pp. 200
Author(s):  
Nadia Ayu Mulansari ◽  
Nanang Sukmana ◽  
Bambang Setyohadi ◽  
Siti Setiati
Keyword(s):  
Bone Mineral Density ◽  
Bone Mass ◽  
Bone Mineral ◽  
Mass Density ◽  
Bone Mass Density ◽  
Mineral Density ◽  
Cross Sectional ◽  
Keywords Hiv ◽  
Hiv Seropositive ◽  
Hiv Aids

Pendahuluan. Tingginya angka kejadian HIV/AIDS pada usia muda yang mencapai 50% dari total kasus HIV/AIDS di Indonesia menjadi permasalahan yang serius, khususnya terkait kualitas hidup pasien. Selain infeksi oportunistik, keadaan osteopenia dan juga osteoporosis sering ditemukan pada pasien dengan HIV/AIDS. Namun demikian, penelitian mengenai gambaran massa tulang pada pasien HIV/AIDS di Indonesia sampai saat ini belum didapatkan.Metode. Studi potong lintang dilakukan pada pasien dewasa dengan infeksi HIV naif antiretroviral di Rumah Sakit dr. Cipto Mangunkusumo (RSCM) Jakarta pada Februari-Mei 2008. Pemeriksaan bone mineral density (BMD) dilakukan dengan menggunakan DXA scanning. Hasil. Berdasarkan pemeriksaan BMD didapatkan sebanyak 29,3% subjek ostopenia, 1,3% osteoporosis dan sisanya normal. Osteopenia/osteoporosis didapatkan lebih besar pada subjek yang mengonsumsi alkohol, merokok, hitung limfosit CD4+ <200 sel/mm3 dan IMT<18,5 dengan proporsi masing-masing secara berturut-turut yaitu 53,6%; 36,9%; 35,5%; dan 37,6%. Lama infeksi HIV pada penelitian ini tidak menunjukkan hasil yang berbeda.Simpulan. Didapatkan keadaan osteopenia dan osteoporosis pada pasien dengan HIV/AIDS. Pada pasien HIV/AIDS dengan riwayat merokok, konsumsi alkohol, hitung limfosit CD4+ <200 sel/mm3 dam IMT rendah, didapatkan angka osteopenia/osteoporosis yang lebih tinggi.Kata kunci: HIV, naif antiretroviral, osteopenia/osteoporosis Bone Mass Density in HIV/AIDS PatientsIntroduction. Indonesia has a high incidence of young HIV-positive population which is 20-29 years of age is in the highest group (50%). For this reason, it is important to make a better quality of life for them. Unfortunately, beside all the opportunistic infection, it was proved that osteopenia/osteoporosis has become a new emerging metabolic condition for HIV-infected patients. There is still no study about the description of bone mass density in HIV/AIDS patients in Indonesia. Methods. A cross sectional study was conducted in a total of 75 HIV-seropositive antiretroviral-naïve patients. Bone mineral density (BMD) was determined by dual energy X-ray absorptiometry in lumbar spine. Results. Seventy-five subjects had been recruited. Low BMD was found in 29.3% HIV-seropositive patients with osteopenia and 1,3% with osteoporosis. There was a higher number of osteopenia/osteoporosis in subjects who consume alcohol, smoking, lymphocyte CD4 <200 cells/mm3 and low body mass index (BMI). Duration of infection did not show any differences in both HIV with osteopenia/osteoporosis and subjects with normal bone condition. Conclusions. Osteopenia and osteoporosis were found in patients with HIV/AIDS in RSCM with lower bone density in subjects who consumed alcohol, smoke, lymphocyte CD4 <200 cells/mm3 and low BMI. Keywords: HIV, antiretroviral naïve, osteopenia/osteoporosis 

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