Prevalence of High Risk for Obstructive Sleep Apnoea and Its Risk Factors Among Adults Attending Government Primary Health Clinics in Kuantan

INTRODUCTION: Obstructive sleep apnoea (OSA) is a sleep-related breathing disorder with recurrent episodes of apnoea or hypopnoea occurring during sleep. It is associated with an increased risk of cardiovascular disease. However, there is no applicable study that assesses the risk for OSA at the primary care level. This study aims to assess the prevalence of risk for OSA and its associated risk factors among adults attending primary care clinics. MATERIALS AND METHOD: This cross-sectional study was conducted among 252 adults attending four Klinik Kesihatan in Kuantan, Pahang. A self-administered validated Malay version of the Berlin Questionnaire was used to screen for the High Risk of OSA. The statistical analyses were done using t-statistics and chi-squared test then proceeded with binary logistic regression. RESULTS: The mean age of respondents was 53.3. Most of the respondents were male (54%), Malay (87.7%), and married (79.4%). The prevalence of High Risk for OSA was 32.9%. Among these, 94% of them presented with snoring and 16.9% presented with excessive daytime sleepiness. The risk factors that were significantly associated with High Risk of OSA includes younger age (AOR=0.951 CI=0.923-0.980); higher Body Mass Index (BMI) classification with obese type 1 (AOR=2.604 CI=1.278-5.308), obese type 2 (AOR=3.882 CI=1.078-13.975) and obese type 3 (AOR=6.800 CI=1.164-39.717); higher neck circumference (AOR=1.109 CI=1.007-1.221); hypertension (AOR=2.297 CI=1.122-4.702); and hypercholesterolaemia (AOR=2.040 CI=1.050-3.965). CONCLUSIONS: Nearly one-third of the adults attending primary health clinics were at High Risk for OSA. Screening for OSA was recommended particularly among those of younger age, higher BMI classification, and with co-morbidities.

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Prevalence of Risks for Obstructive Sleep Apnoea and Its Risk Factors among Adults Attending Government Primary Health Clinics in Kuantan

IIUM Medical Journal Malaysia ◽

10.31436/imjm.v18i2.589 ◽

2020 ◽

Vol 18 (2) ◽

Author(s):

Azwan Faiz Amir Hamzah ◽

Mohd Aznan Md Aris ◽

Fa'iza Abdullah ◽

Zamzil Amin Asha'ari

Keyword(s):

Risk Factors ◽

Primary Care ◽

High Risk ◽

Obstructive Sleep Apnoea ◽

Excessive Daytime Sleepiness ◽

Daytime Sleepiness ◽

Sleep Apnoea ◽

Primary Health ◽

Younger Age ◽

Obstructive Sleep

Introduction: Obstructive sleep apnoea (OSA) is a sleep related breathing disorder with recurrent episodes of apnoea or hypopnoea occurring during sleep. It is associated with increased risk of cardiovascular disease and prone to accidents. However, there is no applicable study that assess the risk for OSA at the primary care level. Objective: This study aims to assess the prevalence of risk for OSA and OSA symptoms and its associated risk factors among adults attending primary care clinics. Materials and method: This cross-sectional study was conducted among 252 adults attending four Klinik Kesihatan in Kuantan, Pahang. The inclusion criteria was adults age 30 years old and above. The exclusion criteria were a known case of Hypothyroidism, Depression and pregnancy. A self-administered validated Malay version of Berlin Questionnaire(BQ) was used to screen for high risk of OSA. The statistical analyses were done using IBM SPSS version 23.0. Results: Majority of the respondents were male (54%), Malay (87.7%), and married (79.4%). The prevalence of High Risk for OSA was 32.9%. Among these, 94% of them presented with snoring and 16.9% presented with excessive daytime sleepiness. Among male, Malay and married; 48%, 32.6% and 36.5% respectively was shown to be High Risk for OSA. The risk factors that were found significantly associated with High Risk of OSA includes younger age (AOR=0.951 CI=0.923-0.980); higher BMI classification with obese type 1 (AOR=2.604 CI=1.278-5.308), obese type 2 (AOR=3.882 CI=1.078-13.975) and obese type 3 (AOR=6.800 CI=1.164-39.717); higher neck circumference (AOR=1.109 CI=1.007-1.221); hypertension (AOR=2.297 CI=1.122-4.702); and hypercholestrolaemia (AOR=2.040 CI=1.050-3.965). Conclusions: This study shows that nearly one third of the adults attending primary health clinic are at High Risk for OSA and nearly 17% of them presented with excessive daytime sleepiness. Further study need to be carry out particularly among those of younger age, higher BMI classification, and with co-morbidities.

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Prevalence of high risk obstructive sleep apnoea by Berlin questionnaire in patients with hypertension: study from a tertiary care hospital

Sleep Science and Practice ◽

10.1186/s41606-020-00052-0 ◽

2020 ◽

Vol 4 (1) ◽

Author(s):

Ozaifa Kareem ◽

Masood Tanvir ◽

G. N. Bader

Keyword(s):

High Risk ◽

Obstructive Sleep Apnoea ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Sleep Apnoea ◽

Berlin Questionnaire ◽

Care Hospital ◽

Cross Sectional ◽

Obstructive Sleep ◽

The Mean

Abstract Background Obstructive Sleep Apnoea (OSA), a condition characterized by a complete or partial cessation of airflow during sleep, can cause various cardiovascular disorders including hypertension. The aim of the study was to determine the prevalence of OSA in patients with hypertension. Methods A cross-sectional prospective cohort study of 504 patients with hypertension was undertaken at a tertiary care hospital of India for a period of 6 months. OSA was evaluated using the Berlin questionnaire while the daytime sleepiness was determined using Epworth Sleepiness Scale. Data analysis was done using SPSS v. 20. Results High risk of OSA was identified in 120 (23.8%) patients and the prevalence of sleepiness (Epworth Sleepiness score >16) was found to be 32.5% (95% CI, p < 0.001) in these patients. The mean neck circumference, waist circumference and waist-to-hip ratio for high-risk OSA group were 37.41 ± 3.396 cm, 105.90 ± 11.28 cm and 1.01 ± 0.065 respectively while for the low-risk group, these parameters were 35.45 ± 2.652 cm, 98.75 ± 10.87 cm and 0.99 ± 0.080 respectively (95% CI, p<0.001). The mean blood pressure (BP) ≥133.52/84.37 mmHg was recorded in patients with a high risk of OSA (95% CI, P < 0.05), and resistant hypertension (3.3%) was significantly associated with the risk of OSA (95% CI, P < 0.05). Conclusion In the tertiary health care setting, the prevalence of high-risk of OSA in patients with hypertension is high. Screening for OSA should be a part of the hypertensive medical investigation and patients may benefit from a proper evaluation of OSA.

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Prevalence of High Risk Obstructive Sleep Apnoea by Berlin Questionnaire in Patients with Hypertension: Study from a Tertiary Care Hospital

10.21203/rs.3.rs-50792/v2 ◽

2020 ◽

Author(s):

Ozaifa Kareem ◽

Masood Tanvir ◽

Ghulam Nabi Bader

Keyword(s):

High Risk ◽

Obstructive Sleep Apnoea ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Sleep Apnoea ◽

Berlin Questionnaire ◽

Care Hospital ◽

Cross Sectional ◽

Obstructive Sleep ◽

The Mean

Abstract Background: Obstructive Sleep Apnoea (OSA), a condition characterized by a complete or partial cessation of airflow during sleep, can cause various cardiovascular disorders including hypertension. The aim of the study was to determine the prevalence of OSA in patients with hypertension. Methods: A cross-sectional prospective cohort study of 504 patients with hypertension was undertaken at a tertiary care hospital of India for a period of six months. OSA was evaluated using the Berlin questionnaire while the daytime sleepiness was determined using Epworth Sleepiness Scale. Data analysis was done using SPSS v. 20. Results: High risk of OSA was identified in 120 (23.8%) patients and the prevalence of sleepiness (Epworth Sleepiness score ˃16) was found to be 32.5% (95% CI, p˂0.001) in these patients. The mean neck circumference, waist circumference and waist-to-hip ratio for high-risk OSA group were 37.41 ± 3.396 cm, 105.90 ± 11.28 cm and 1.01 ± 0.065 respectively while for the low-risk group, these parameters were 35.45 ± 2.652 cm, 98.75 ± 10.87 cm and 0.99 ± 0.080 respectively (95% CI, p˂0.001). The mean blood pressure (BP) ≥133.52/84.37 mm Hg was recorded in patients with a high risk of OSA (95% CI, P<0.05), and resistant hypertension (3.3%) was significantly associated with the risk of OSA (95% CI, P<0.05).Conclusion: In the tertiary health care setting, the prevalence of high-risk of OSA in patients with hypertension is high. Screening for OSA should be a part of the hypertensive medical investigation and patients may benefit from a proper evaluation of OSA.

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Prevalence of Obstructive Sleep Apnoea in Patients with Hypertension: Study from a Tertiary Care Hospital

10.21203/rs.3.rs-50792/v1 ◽

2020 ◽

Author(s):

Ozaifa Kareem ◽

Masood Tanvir ◽

Ghulam Nabi Bader

Keyword(s):

High Risk ◽

Obstructive Sleep Apnoea ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Sleep Apnoea ◽

Berlin Questionnaire ◽

Care Hospital ◽

Cross Sectional ◽

Obstructive Sleep ◽

The Mean

Abstract Background: Obstructive Sleep Apnoea (OSA), a condition characterized by a complete or partial cessation of airflow during sleep, can cause various cardiovascular disorders including hypertension. The aim of the study was to determine the prevalence of OSA in patients with hypertension. Methods: A cross-sectional prospective cohort study of 504 patients with hypertension was undertaken at a tertiary care hospital of India for a period of six months. OSA was evaluated using the Berlin questionnaire and the Epworth Sleepiness Scale. Data analysis was done using SPSS v. 20. Results: High risk of OSA was identified in 120 (23.8%) patients and the prevalence of sleepiness (Epworth Sleepiness score ˃16) was found to be 32.5% (95% CI, p˂0.001) in these patients. The mean neck circumference, waist circumference and waist-to-hip ratio for high-risk OSA group were 14.75 ± 1.338 inches, 105.90 ± 11.28 cm and 1.01 ± 0.065 respectively while for the low-risk group, these parameters were 13.97 ± 1.045 inches, 98.75 ± 10.87 cm and 0.99 ± 0.080 respectively (95% CI, p˂0.001). The mean blood pressure (BP) ≥133.52/84.37 mm Hg was recorded in patients with a high risk of OSA (95% CI, P<0.05), and resistant hypertension (3.3%) was significantly associated with the risk of OSA (95% CI, P<0.05).Conclusion: In the tertiary health care setting, the prevalence of high-risk of OSA in patients with hypertension is high. Screening for OSA should be a part of the hypertensive medical investigation and patients may benefit from a proper evaluation of OSA.

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Prevalence of Obstructive Sleep Apnoea in Patients with Hypertension: Study from a tertiary care hospital

10.21203/rs.2.11327/v1 ◽

2019 ◽

Author(s):

Ozaifa Kareem ◽

Masood Tanvir ◽

Ghulam N Bader

Keyword(s):

High Risk ◽

Obstructive Sleep Apnoea ◽

Tertiary Care ◽

Sleep Apnoea ◽

Berlin Questionnaire ◽

Care Hospital ◽

Cross Sectional ◽

Obstructive Sleep ◽

The Mean ◽

Scale Data

Abstract Background: Obstructive Sleep Apnoea (OSA), a condition characterized by a complete or partial cessation of airflow during sleep, can cause various cardiovascular disorders including hypertension. The aim of the study was to determine the prevalence of OSA in patients with hypertension. Methods: A cross-sectional prospective cohort study of 504 patients (253 males and 251 females) with hypertension was undertaken at Shri-Maharaja Hari Singh (SMHS) Hospital of Srinagar, India for a period of six months. OSA was evaluated using Berlin questionnaire and Epworth Sleepiness scale. Data analysis was done using SPSS v. 20. Results: High risk of OSA was identified in 120 (23.8%) patients and the prevalence of sleepiness (Epworth Sleepiness score ˃16) was found to be 32.5% (95% CI, P˂0.001) in these patients. The mean neck circumference, waist circumference and waist-to-hip ratio for high-risk OSA group was 14.75 ± 1.338 inches, 105.90 ± 11.28 cm and 1.01 ± 0.065 respectively while for the low-risk group, these parameters were 13.97 ± 1.045 inches, 98.75 ± 10.87 cm and 0.99 ± 0.080 respectively (95% CI, P˂0.001). The mean blood pressure (BP) ≥133.52/84.37 mm Hg was recorded in patients with high risk of OSA (95% CI, P<0.05) and resistant hypertension (3.3%) was significantly associated with the risk of OSA (95% CI, P<0.05). Conclusion: In the tertiary health care setting, the prevalence of high-risk of OSA in patients with hypertension is high. Screening for OSA should be a part of the hypertensive medical investigation and patients may benefit from proper evaluation of OSA.

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Using the Berlin Questionnaire To Identify Pre-Operative Patients at High Risk of Obstructive Sleep Apnoea.

10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a2138 ◽

2009 ◽

Author(s):

J D'Costa ◽

E Peak ◽

S Mackay ◽

D Simmons ◽

RD McEvoy ◽

...

Keyword(s):

High Risk ◽

Obstructive Sleep Apnoea ◽

Sleep Apnoea ◽

Berlin Questionnaire ◽

Obstructive Sleep

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Relationship Between Obstructive Sleep Apnoea, Oxygen Desaturation and Cardiovascular Risk

Revista de Chimie ◽

10.37358/rc.19.10.3582 ◽

2019 ◽

Vol 70 (10) ◽

pp. 3582-3586

Keyword(s):

Risk Factors ◽

Coronary Heart Disease ◽

Heart Disease ◽

Cardiovascular Risk ◽

Obstructive Sleep Apnoea ◽

Cardiovascular Events ◽

Sleep Apnoea ◽

Oxygen Desaturation ◽

Obstructive Sleep Apnoea Syndrome ◽

Obstructive Sleep

Obstructive sleep apnoea syndrome (OSAS) increases the risk cardiovascular events regardless of the presence of previous cardiovascular disease. As both OSAS and coronary heart disease (CHD) have same risk factors it’s often difficult to quantify the proportion of each risk factor in developing cardiac events. The aim of this study was to evaluate the 10-year risk of developing a coronary heart disease (CHD) event or stroke in newly diagnosed OSAS patients. 65 patients diagnosed with OSAS over a period of four months in Oradea Sleep Laboratory were included. Demographic characteristics, anthropometric parameters, clinical and biochemical data, sleep disorder and daytime sleepiness assessment, results of polysomnography were collected in all patients. In 55 selected patients by age range from 34 to 74 years old, cardiovascular risk was assessed using Framingham score calculator. Statistical analysis was performed using SPSS-PC version 7.5 and Stata 10.The estimated 10-years risk of a CHD event was 18.97% (± 9.67) in all cases. It was higher in men (22.17% ± 9.24) compare to women (12.39% ± 6.92) and it was not significantly different by stages of OSAS severity (20.58% ±9.41 in patients with severe OSAS versus 15.4% in mild OSAS), suggesting that apnea hypopnea index is not a major confounding factor. Desaturation of oxygen is a better outcome to define the relation between OSAS and cardiovascular diseases. OSAS and cardiovascular risk factors increased risk for future adverse cardiovascular events related to the severity of oxygen desaturation. Keywords: obstructive sleep apnoea syndrome, cardiovascular events, risk factors, oxygen desaturation

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