scholarly journals Prevalence of High Risk Obstructive Sleep Apnoea by Berlin Questionnaire in Patients with Hypertension: Study from a Tertiary Care Hospital

2020 ◽  
Author(s):  
Ozaifa Kareem ◽  
Masood Tanvir ◽  
Ghulam Nabi Bader
Keyword(s):  
High Risk ◽  
Obstructive Sleep Apnoea ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Sleep Apnoea ◽  
Berlin Questionnaire ◽  
Care Hospital ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Mean

Abstract Background: Obstructive Sleep Apnoea (OSA), a condition characterized by a complete or partial cessation of airflow during sleep, can cause various cardiovascular disorders including hypertension. The aim of the study was to determine the prevalence of OSA in patients with hypertension. Methods: A cross-sectional prospective cohort study of 504 patients with hypertension was undertaken at a tertiary care hospital of India for a period of six months. OSA was evaluated using the Berlin questionnaire while the daytime sleepiness was determined using Epworth Sleepiness Scale. Data analysis was done using SPSS v. 20. Results: High risk of OSA was identified in 120 (23.8%) patients and the prevalence of sleepiness (Epworth Sleepiness score ˃16) was found to be 32.5% (95% CI, p˂0.001) in these patients. The mean neck circumference, waist circumference and waist-to-hip ratio for high-risk OSA group were 37.41 ± 3.396 cm, 105.90 ± 11.28 cm and 1.01 ± 0.065 respectively while for the low-risk group, these parameters were 35.45 ± 2.652 cm, 98.75 ± 10.87 cm and 0.99 ± 0.080 respectively (95% CI, p˂0.001). The mean blood pressure (BP) ≥133.52/84.37 mm Hg was recorded in patients with a high risk of OSA (95% CI, P<0.05), and resistant hypertension (3.3%) was significantly associated with the risk of OSA (95% CI, P<0.05).Conclusion: In the tertiary health care setting, the prevalence of high-risk of OSA in patients with hypertension is high. Screening for OSA should be a part of the hypertensive medical investigation and patients may benefit from a proper evaluation of OSA.

scholarly journals Prevalence of high risk obstructive sleep apnoea by Berlin questionnaire in patients with hypertension: study from a tertiary care hospital

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Ozaifa Kareem ◽  
Masood Tanvir ◽  
G. N. Bader
Keyword(s):  
High Risk ◽  
Obstructive Sleep Apnoea ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Sleep Apnoea ◽  
Berlin Questionnaire ◽  
Care Hospital ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Mean

Abstract Background Obstructive Sleep Apnoea (OSA), a condition characterized by a complete or partial cessation of airflow during sleep, can cause various cardiovascular disorders including hypertension. The aim of the study was to determine the prevalence of OSA in patients with hypertension. Methods A cross-sectional prospective cohort study of 504 patients with hypertension was undertaken at a tertiary care hospital of India for a period of 6 months. OSA was evaluated using the Berlin questionnaire while the daytime sleepiness was determined using Epworth Sleepiness Scale. Data analysis was done using SPSS v. 20. Results High risk of OSA was identified in 120 (23.8%) patients and the prevalence of sleepiness (Epworth Sleepiness score >16) was found to be 32.5% (95% CI, p < 0.001) in these patients. The mean neck circumference, waist circumference and waist-to-hip ratio for high-risk OSA group were 37.41 ± 3.396 cm, 105.90 ± 11.28 cm and 1.01 ± 0.065 respectively while for the low-risk group, these parameters were 35.45 ± 2.652 cm, 98.75 ± 10.87 cm and 0.99 ± 0.080 respectively (95% CI, p<0.001). The mean blood pressure (BP) ≥133.52/84.37 mmHg was recorded in patients with a high risk of OSA (95% CI, P < 0.05), and resistant hypertension (3.3%) was significantly associated with the risk of OSA (95% CI, P < 0.05). Conclusion In the tertiary health care setting, the prevalence of high-risk of OSA in patients with hypertension is high. Screening for OSA should be a part of the hypertensive medical investigation and patients may benefit from a proper evaluation of OSA.

scholarly journals Prevalence of Obstructive Sleep Apnoea in Patients with Hypertension: Study from a Tertiary Care Hospital

2020 ◽  
Author(s):  
Ozaifa Kareem ◽  
Masood Tanvir ◽  
Ghulam Nabi Bader
Keyword(s):  
High Risk ◽  
Obstructive Sleep Apnoea ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Sleep Apnoea ◽  
Berlin Questionnaire ◽  
Care Hospital ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Mean

Abstract Background: Obstructive Sleep Apnoea (OSA), a condition characterized by a complete or partial cessation of airflow during sleep, can cause various cardiovascular disorders including hypertension. The aim of the study was to determine the prevalence of OSA in patients with hypertension. Methods: A cross-sectional prospective cohort study of 504 patients with hypertension was undertaken at a tertiary care hospital of India for a period of six months. OSA was evaluated using the Berlin questionnaire and the Epworth Sleepiness Scale. Data analysis was done using SPSS v. 20. Results: High risk of OSA was identified in 120 (23.8%) patients and the prevalence of sleepiness (Epworth Sleepiness score ˃16) was found to be 32.5% (95% CI, p˂0.001) in these patients. The mean neck circumference, waist circumference and waist-to-hip ratio for high-risk OSA group were 14.75 ± 1.338 inches, 105.90 ± 11.28 cm and 1.01 ± 0.065 respectively while for the low-risk group, these parameters were 13.97 ± 1.045 inches, 98.75 ± 10.87 cm and 0.99 ± 0.080 respectively (95% CI, p˂0.001). The mean blood pressure (BP) ≥133.52/84.37 mm Hg was recorded in patients with a high risk of OSA (95% CI, P<0.05), and resistant hypertension (3.3%) was significantly associated with the risk of OSA (95% CI, P<0.05).Conclusion: In the tertiary health care setting, the prevalence of high-risk of OSA in patients with hypertension is high. Screening for OSA should be a part of the hypertensive medical investigation and patients may benefit from a proper evaluation of OSA.

scholarly journals Prevalence of Obstructive Sleep Apnoea in Patients with Hypertension: Study from a tertiary care hospital

2019 ◽  
Author(s):  
Ozaifa Kareem ◽  
Masood Tanvir ◽  
Ghulam N Bader
Keyword(s):  
High Risk ◽  
Obstructive Sleep Apnoea ◽  
Tertiary Care ◽  
Sleep Apnoea ◽  
Berlin Questionnaire ◽  
Care Hospital ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
The Mean ◽  
Scale Data

Abstract Background: Obstructive Sleep Apnoea (OSA), a condition characterized by a complete or partial cessation of airflow during sleep, can cause various cardiovascular disorders including hypertension. The aim of the study was to determine the prevalence of OSA in patients with hypertension. Methods: A cross-sectional prospective cohort study of 504 patients (253 males and 251 females) with hypertension was undertaken at Shri-Maharaja Hari Singh (SMHS) Hospital of Srinagar, India for a period of six months. OSA was evaluated using Berlin questionnaire and Epworth Sleepiness scale. Data analysis was done using SPSS v. 20. Results: High risk of OSA was identified in 120 (23.8%) patients and the prevalence of sleepiness (Epworth Sleepiness score ˃16) was found to be 32.5% (95% CI, P˂0.001) in these patients. The mean neck circumference, waist circumference and waist-to-hip ratio for high-risk OSA group was 14.75 ± 1.338 inches, 105.90 ± 11.28 cm and 1.01 ± 0.065 respectively while for the low-risk group, these parameters were 13.97 ± 1.045 inches, 98.75 ± 10.87 cm and 0.99 ± 0.080 respectively (95% CI, P˂0.001). The mean blood pressure (BP) ≥133.52/84.37 mm Hg was recorded in patients with high risk of OSA (95% CI, P<0.05) and resistant hypertension (3.3%) was significantly associated with the risk of OSA (95% CI, P<0.05). Conclusion: In the tertiary health care setting, the prevalence of high-risk of OSA in patients with hypertension is high. Screening for OSA should be a part of the hypertensive medical investigation and patients may benefit from proper evaluation of OSA.

scholarly journals Gender-wise Comparative Assessment of Lifestyle Patterns and Well-being Status among Healthcare Employees at a Tertiary Care Hospital

2021 ◽  
Author(s):  
Vanajakshamma Velam ◽  
Vyshnavi Kancherla ◽  
Latheef Kasala ◽  
Anusha Kancherla ◽  
Mounica Reddy Pillaram
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Well Being ◽  
Care Hospital ◽  
Cross Sectional ◽  
Significant Difference ◽  
Female Employees ◽  
The Mean ◽  
Lifestyle Patterns ◽  
Comprehensive Study

Abstract Background This study was an attempt to assess and compare the gender-wise lifestyle patterns and well-being status among the employees of a tertiary care teaching hospital. Material and Methods This is a cross-sectional, questionnaire-based study conducted at a tertiary care hospital between May and August 2019. A total of 777 employees belonging to both genders (male and female) and working at different professional levels were assessed. All the enrolled employees were subjected to a comprehensive study tool consisting of various dimensions of their health, which included physical, mental, social, spiritual and intellectual health dimensions. Results Among the participants, 327 (42.1%) were male and 450 (57.9%) were female. There was no significant difference in the mean age of male (37.91 ± 7.52) and female (36.85 ± 8.16) employees (p = 0.07). A significantly higher proportion of diabetes and hypertension were seen in male employees (9.8% and 14.4%, respectively) than in female (5.6% and 6.2% respectively). The overall well-being was better in male employees than in females and was statistically significant (p < 0.0001). We found that male employees had statistically significant better well-being in terms of physical, mental and social health whereas female employees had intellectual health. Conclusion The overall well-being in healthcare staff was good at our tertiary care hospital, and the outstanding/good well-being rate was higher in male employees than in female employees. Female employees experienced risks with regard to their physical health.

scholarly journals Use of monoclonal antibody therapy for nosocomial SARS-CoV-2 infection in patients at high risk for severe COVID-19: experience from a tertiary-care hospital in Germany

Infection ◽  
2021 ◽  
Author(s):  
Johanna Koehler ◽  
Barbara Ritzer ◽  
Simon Weidlich ◽  
Friedemann Gebhardt ◽  
Chlodwig Kirchhoff ◽  
...  
Keyword(s):  
High Risk ◽  
Tertiary Care Hospital ◽  
Severe Disease ◽  
Treatment Options ◽  
Tertiary Care ◽  
Antibody Therapy ◽  
Additional Treatment ◽  
Care Hospital ◽  
Cross Sectional ◽  
Asymptomatic Patients

AbstractAdditional treatment options for coronavirus disease (COVID-19) are urgently needed, particularly for populations at high risk of severe disease. This cross-sectional, retrospective study characterized the outcomes of 43 patients with nosocomial severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection with and without treatment using monoclonal SARS-CoV-2 spike antibodies (bamlanivimab or casirivimab/imdevimab). Our results indicate that treatment with monoclonal antibodies results in a significant decrease in disease progression and mortality when used for asymptomatic patients with early SARS-CoV-2 infection.

Seroprevalence of HBV, HCV, HIV, syphilis, and malaria among blood donors at tertiary care hospital blood bank

2020 ◽  
pp. 1-9
Author(s):  
Hira Qadir ◽  
Nadia Nasir ◽  
Shaheen Kouser ◽  
Huma Mansoori ◽  
Nida Qadir ◽  
...  
Keyword(s):  
Social Sciences ◽  
Blood Donors ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Descriptive Study ◽  
Blood Bank ◽  
Care Hospital ◽  
Cross Sectional ◽  
Disease Markers ◽  
The Mean

Abstract Objective:To ascertain the frequency of markers of transfusion-transmitted infections. among blood donors in a blood bank at a tertiary care hospital Material and Methods:The study was a retrospective cross-sectional descriptive study, covering from 1stJanuary 2013- October 2018 and was conducted in the blood bank section, in the Department of Pathology at Dow University of HealthSciences, Hospital. All blood donors were screened for hepatitis B, hepatitis C, HIV (I & II), syphilis through electrochemiluminescence and malaria (immunochromatography).Data was entered and subsequently analyzed by statistical package for social sciences (SPSS) version 21. The frequency of infectious disease markers (HbsAg, Anti HCV, HIV, syphilis, and malaria) was calculated among blood donors. Results:The total number of donors in our study was 29732, out of which 2587 donors were positive for an infectious disease.Out of the total donors, 29712 were male and 20 were female. There were 12 volunteer donors and 29720 exchange donors. The mean prevalence of donors with positive infectious markers was as follows; Anti HCV was 3 %, HbsAg was 2.9%, Syphilis was 2.0%, HIV was 0.5% and Malaria was 0.02 %. Conclusion:HbsAg and Anti HCV were the most frequent infections (3%) found in our blood donors, followed by syphilis with a frequency of 2%. Keywords: Blood transfusion, transfusion-transmitted infections, blood donors.

scholarly journals Postpartum Hemorrhage in Pregnancy beyond 40 Weeks of Gestation in a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (237) ◽  
Author(s):  
Rashmi Bastakoti Gaire ◽  
Suman Raj Tamrakar ◽  
Anjana Singh Dongol
Keyword(s):  
High Risk ◽  
Confidence Interval ◽  
Postpartum Hemorrhage ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
In Pregnancy

Introduction: Postpartum hemorrhage is defined as a blood loss of 500ml or more within 24 hours after birth. It is the leading cause of maternal mortality in low-income countries and the primary cause of nearly one-quarter of all maternal deaths globally. It occurs in up to 18% of total births. Post-dated pregnancy is a high-risk pregnancy with increased maternal morbidity. This study aims to determine the prevalence of postpartum hemorrhage in pregnancy beyond 40 weeks of gestation in a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted among pregnant women beyond 40 weeks in Dhulikhel hospital from October 2016 to March 2017. The study was conducted after ethical clearance from the hospital research committee (reference number#128/16). The sample size was calculated and convenient sampling was done. Statistical Package for the Social Sciences is used for analysis. Point estimate at 95% confidence interval was calculated along with frequency and percentage for binary data. Results: Out of 465 ladies enrolled in this study postpartum hemorrhage was seen in 6 (1.29%) (95% Confidence Interval = 0.267-2.31), and the mean age was 24.25+4.8. About 346 (74.4%) had a normal delivery, 104 (22.36%) had cesarean section and 15 (3.22%) had instrumental delivery. Conclusions: Postpartum haemorrhage prevalence is low among the pregnant women beyond 40 weeks compared to the standard study. Postpartum hemorrhage is the common leading cause of maternal mortality. So high-risk cases should be identified and active management should be done to reduce morbidity and mortality.

scholarly journals Prevalence of High Risk for Obstructive Sleep Apnoea and Its Risk Factors Among Adults Attending Government Primary Health Clinics in Kuantan

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Md Aris MA ◽  
Amir Hamzah AF ◽  
Abdullah F ◽  
Asha’ari ZA
Keyword(s):  
Risk Factors ◽  
Primary Care ◽  
High Risk ◽  
Obstructive Sleep Apnoea ◽  
Sleep Apnoea ◽  
Berlin Questionnaire ◽  
Health Clinics ◽  
Primary Health ◽  
Younger Age ◽  
Obstructive Sleep

INTRODUCTION: Obstructive sleep apnoea (OSA) is a sleep-related breathing disorder with recurrent episodes of apnoea or hypopnoea occurring during sleep. It is associated with an increased risk of cardiovascular disease. However, there is no applicable study that assesses the risk for OSA at the primary care level. This study aims to assess the prevalence of risk for OSA and its associated risk factors among adults attending primary care clinics. MATERIALS AND METHOD: This cross-sectional study was conducted among 252 adults attending four Klinik Kesihatan in Kuantan, Pahang. A self-administered validated Malay version of the Berlin Questionnaire was used to screen for the High Risk of OSA. The statistical analyses were done using t-statistics and chi-squared test then proceeded with binary logistic regression. RESULTS: The mean age of respondents was 53.3. Most of the respondents were male (54%), Malay (87.7%), and married (79.4%). The prevalence of High Risk for OSA was 32.9%. Among these, 94% of them presented with snoring and 16.9% presented with excessive daytime sleepiness. The risk factors that were significantly associated with High Risk of OSA includes younger age (AOR=0.951 CI=0.923-0.980); higher Body Mass Index (BMI) classification with obese type 1 (AOR=2.604 CI=1.278-5.308), obese type 2 (AOR=3.882 CI=1.078-13.975) and obese type 3 (AOR=6.800 CI=1.164-39.717); higher neck circumference (AOR=1.109 CI=1.007-1.221); hypertension (AOR=2.297 CI=1.122-4.702); and hypercholesterolaemia (AOR=2.040 CI=1.050-3.965). CONCLUSIONS: Nearly one-third of the adults attending primary health clinics were at High Risk for OSA. Screening for OSA was recommended particularly among those of younger age, higher BMI classification, and with co-morbidities.

scholarly journals Emergency Stay Duration of Patients in Emergency Department of A Tertiary Care Hospital in Nepal: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (222) ◽  
Author(s):  
Prashant Simkhada ◽  
Shradha Acharya ◽  
Roshan Lama ◽  
Sujata Dahal ◽  
Nita Lohola ◽  
...  
Keyword(s):  
Emergency Department ◽  
Length Of Stay ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Duration Of Stay ◽  
The Mean

Introduction: Emergency department of a hospital is responsible for providing medical and surgical care to patients arriving at the hospital in need of immediate care. Emergency department is not staffed or equipped to provide prolonged care. Duration of stay in the Emergency department directly affects the quality of patient care. Longer length of stay is associated with Emergency department overcrowding, decline in patient care, increased mortality and decreased patients satisfaction. The main aim of this study is to find the mean stay duration of patients in the emergency department of a tertiary care hospital in Nepal.Methods: This is a descriptive cross-sectional study which was conducted in a tertiary care teaching hospital from Jan 15,2019 to Jan 30, 2019. Ethical clearance was obtained from Kathmandu Medical College- Instutional Review Committee. The calculated sample size was 587. Consecutive sampling technique was used. The data thus obtained was entered in SPSS version 20 and necessary calculations were done. Results: The mean emergency stay duration was obtained to be 3.18 hours at 95% confidence interval (C.I  and standard deviation was 2.51 hours. Female had longer mean duration of stay (3.25 hours) compared to male (3.11 hours). The maximum length of stay was 15.3 hours. Most of the patients attending the emergency department were discharged right through the emergency department 398 ( 67.8%). Mean duration of stay was longest (5.06 hours) for the referral group. Conclusions: The mean stay duration in Emergency Department of tertiary care hospital in Nepal is getting shorter compared to similar study done previously.

scholarly journals Study of drug utilization pattern in gynecology department of tertiary care hospital of Rajasthan, India

2018 ◽  
Vol 7 (7) ◽  
pp. 2650
Author(s):  
Neelam Sharma ◽  
Anshul Jhanwar
Keyword(s):  
Drug Utilization ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Utilization Pattern ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
Related Information ◽  
The Mean

Background: With increasing awareness the flow of patients visiting gynecology outpatient department has increased. Drugs used in gynecology are one of the most selling drugs in India, however they are least studied with respect to drug utilization. Thus, present study was undertaken to analyse drug utilization pattern of Gynecology OPD in a tertiary care hospital.Methods: A retrospective, cross sectional, observational study of prescriptions in Gynecology OPD of Jhalawar medical college, Jhalawar. Data was obtained from medical record database of patients that attended Gynecology OPD from October 2017 to March 2018 over period of six months. Prescription records of patients were screened as per inclusion and exclusion criteria and 300 prescriptions were randomly selected. Patient related, and drug related information was collected on a customized data collection sheet.Results: The mean age of patients was 20.5±8.65 years and common age of presentation was >18-30 years. In infective cases, PID (40.6%) was common, and in non-infective cases, menorrhagia (23.8%) was common. The average number of drugs per prescription was 5.2. In drug category, minerals (46.4%) were most commonly prescribed, followed by antimicrobials (27.6%), and NSAIDs (20.1%). Polypharmacy was observed in 100% of the prescriptions.Conclusions: In the present study all of the drugs prescribed were generic which were from the essential medical list of NLEM and WHO. This study revealed deviation from rational prescribing by the prescribers because average number of drugs per prescription was significantly higher than that recommended by WHO.

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