scholarly journals Intra-Abdominal Malignant Solitary Fibrous Tumor with Peritoneal Dissemination: A Case Report

Author(s):  
Vivian Ma ◽  
Vivian Ma ◽  
Lawrence Turner ◽  
Robert van Wiltenburg ◽  
Conrad D Oja ◽  
...  

Solitary fibrous tumor (SFT) is a rare mesenchymal tumor primarily found in the pleura, with occasional presentations in extra-pleural locations. SFTs are typically diagnosed based on compressive symptoms due to their large size. Most SFTs are benign with a low recurrence rate, with an overall good prognosis with an overall 5-year survival of over 90%. Approximately 12-22% of SFTs are malignant and are associated with a higher recurrence rate of up to 78%. Given the low incidence and sparse case series literature, no adjuvant therapies have demonstrated a survival benefit. We present the first case of abdominal malignant SFTs with peritoneal dissemination, describing the presentation, histopathology, treatment planning and surveillance.

2017 ◽  
Vol 103 (1_suppl) ◽  
pp. S9-S11 ◽  
Author(s):  
Nicola Tamburini ◽  
Nicolò Fabbri ◽  
Gabriele Anania ◽  
Pio Maniscalco ◽  
Francesco Quarantotto ◽  
...  

Introduction Solitary fibrous tumor of the pleura is an uncommon tumor with an indolent course and a good prognosis after surgical resection. However, the tumor occasionally follows an unpredictable clinical course and malignant transformation has been reported to increase the rate of local recurrence. Solitary extrathoracic metastasis from solitary fibrous tumor of the pleura is an uncommon finding. Case Presentation In this case report we present the first case of a synchronous single pulmonary and pancreatic metastasis treated with minimally invasive surgery. Conclusions Pancreatic recurrence should be considered in the postoperative follow-up in patients with solitary fibrous tumor of the pleura.


2013 ◽  
Vol 2013 ◽  
pp. 1-6
Author(s):  
Javier Cuello ◽  
Ricardo Brugés

Solitary fibrous tumors of the kidney are extremely rare tumors with unpredictable behavior. We describe a case of a patient with a solitary fibrous tumor of kidney with malignant findings with distant metastasis and nephrectomy managed with subcutaneous interferon achieving 23 months of progression-free survival. To date there is no prospective evaluation of any specific modality of treatment, but the surgical management and long-term followup are the only ones so far recommended strategies in the management of these patients. Studies are awaited with more patients to evaluate the different strategies of systemic therapy reported so far to allow adding survival benefit.


2021 ◽  
Vol 11 ◽  
Author(s):  
Jingwen Zhang ◽  
Jumin Liu ◽  
Zhihao Zhang ◽  
Beizong Tian

BackgroundA solitary fibrous tumor of the chest (SFTC) is a subtype of solitary fibrous tumor (SFT) with a low incidence rate. The purpose of this study is to analyze the diagnosis and treatment of SFTC and the difference between benign and malignant solitary fibrous tumor of the pleura (SFTP) to improve the understanding of this rare disease.MethodsA retrospective analysis of fifty patients with SFTC (33 cases in the pleura and 17 in the lung) was performed. Clinical and imaging characteristics, pathological features, and treatment follow-up outcomes were analyzed.ResultsThe common symptoms of the 50 patients included a cough, expectoration, chest tightness, fever, and chest pain. Space occupying lesions were found via plain computed tomography (CT) and enhanced CT was used for enhancement of the tumors. It was also found that 18 cases had necrosis, and 5 cases had calcification. The histopathology results showed that frequent nuclear division, obvious morphological variation, necrosis, and the high expression of Ki-67 cells are markers of malignant SFTC. There were significant differences in age, chest tightness, necrotic foci in CT, and expression of Ki-67 between the benign and malignant SFTP cases. All the patients who received treatment were given an excellent prognosis.ConclusionA combination of enhanced CT, histopathology, and immunohistochemistry can be used for the accurate diagnosis of SFTC. Advanced age, chest tightness, necrotic foci in CT, and a high Ki-67 index were more likely to be malignant SFTP. Operation and radiofrequency ablation can provide favorable outcomes for both benign and malignant SFTC.


2018 ◽  
Vol 48 ◽  
pp. 48-54 ◽  
Author(s):  
Adrian Fernandez ◽  
Miles Conrad ◽  
Ryan M. Gill ◽  
Won-Tak Choi ◽  
Vishal Kumar ◽  
...  

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. 11042-11042 ◽  
Author(s):  
Maristella Saponara ◽  
Bruno Vincenzi ◽  
Giuseppe Badalamenti ◽  
Carlo Morosi ◽  
Silvana Pilotti ◽  
...  

2014 ◽  
Vol 82 (2) ◽  
pp. 127-129 ◽  
Author(s):  
Daniele Castellani ◽  
Giancarlo Sebastiani ◽  
Simone Maurelli ◽  
Alessandro Andrisano ◽  
Luigi Mazzone ◽  
...  

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Brian Cervenka ◽  
Brenda Villegas ◽  
Uttam Sinha

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm that can present essentially anywhere in the body. Presentations in the hypopharynx are extremely rare with only two previous cases reported. We report the first case of postcricoid SFT occurring in a 58-year-old male requiring a microsuspension laryngoscopy excision following an unsuccessful transoral robotic attempt. The excision was uneventful, and the patient is currently without recurrence. Current management strategies of the hypopharyngeal SFT, the unique differential diagnosis, and challenges in surgical approaches in the postcricoid region are discussed.


Orbit ◽  
2008 ◽  
Vol 27 (6) ◽  
pp. 426-431 ◽  
Author(s):  
Eric S. Tam ◽  
Edmund C. Chen ◽  
Navdeep Nijhawan ◽  
John T. Harvey ◽  
David Howarth ◽  
...  

2020 ◽  
Vol 11 ◽  
pp. 238
Author(s):  
Hammad Ghanchi ◽  
Tye Patchana ◽  
Eisha Christian ◽  
Chao Li ◽  
Mark Calayag

Background: Solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) is a rare tumor which originates from the walls of capillaries and has historically been thought to be able to occur anywhere in the body that blood vessels are found. It is rarely found in the sellar region. Case Description: InS this report, we present the first case of this tumor occurring in the sellar region of a pediatric patient. This 12-year-old male presented with progressive vision loss which prompted surgical resection after a sellar lesion was discovered on imaging. The initial transsphenoidal approach resulted in subtotal resection and the patient experienced reoccurrence within 3 months. He underwent an orbitozygomatic craniotomy to achieve gross total tumor resection. Conclusion: We conducted a literature review of intracranial SFT/HPC in the pediatric population and found it to be an extremely rare occurrence, with <30 cases reported. The incidence of SFT/HPC occurring in the sellar region for any age group was also found to be a rare entity. Treatment recommendations for this tumor are also scarce, based on retrospective chart reviews from the adult population. The role for adjuvant radiation has mixed results.


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