scholarly journals Microbiota Against SARS CoV-2: Case Reports and a Model for Stopping the COVID-19 Pandemic

Author(s):  
Goran Belojevic ◽  
Goran Belojevic

Background: The aim of this work is to present two case reports of successful prevention and treatment of the COVID-19 and to propose a model for stopping the COVID-19 pandemic with probiotics. Material and Methods: We present two case reports during the COVID-19 epidemic in Serbia in which probiotics were used for the prevention and treatment of the COVID-19. Based on the biological plausibility we propose a model for stopping the COVID-19 pandemic with probiotics. Results: In Case 1, a female (75), chain smoker, asthmatic, gets a fever (38.5ºC), and a pronounced weakness. Treated at home with paracetamol. The next morning fever (39.0ºC), more pronounced weakness. We advise to stop with paracetamol and to take a probiotic, 3x1 tablet (4x10exp9 CFU Lactobacillus and Bifidobacterium spec.) during a meal. The same night temperature falls and remains at 36.9ºC, weakness disappears. Feeling healthy and strong ever since. Negative on the ELISA test for the COVID-19. In Case 2, a male, (63), hypertensive, has got infected from a colleague at work who was treated for the COVID-19 in a hospital. Did not take probiotics as prevention. Treated at home with a symptomatic therapy for two weeks, with the symptoms of fever, dry cough, and pronounced weakness. Positive on the ELISA test for the COVID-19. His wife (57), who had been taking one probiotic daily regularly, has felt healthy ever since, although they have slept together. We propose a model for stopping the COVID-19 pandemic. Advice the whole population to take one capsule of probiotics Lactobacillus and Bifidobacterium, during a meal. Those with COVID-19 one capsule three times daily. Those who are on mechanical ventilation- two capsules three times daily. Conclusion: Based on case reports and the biological plausibility we propose a model for stopping the COVID-19 pandemic with probiotics.

Author(s):  
Anshu Bamney ◽  
Hisham Jashami ◽  
Sarvani Sonduru Pantangi ◽  
Jayson Ambabo ◽  
Megat-Usamah Megat-Johari ◽  
...  

The COVID-19 pandemic has had far-reaching impacts on public health and safety, economics, and the transportation system. To reduce the spread of this disease, federal and local governments around the world have introduced stay-at-home orders and other restrictions on travel to “non-essential” businesses to implement social distancing. Preliminary evidence suggests substantial variability in the impacts of these orders in the United States, both across states and over time. This study examines this issue using daily county-level vehicle miles traveled (VMT) data for the 48 continental U.S. states and the District of Columbia. A two-way random effects model is estimated to assess changes in VMT from March 1 to June 30, 2020 as compared with baseline January travel levels. The implementation of stay-at-home orders was associated with a 56.4 percent reduction in VMT on average. However, this effect was shown to dissipate over time, which may be attributable to “quarantine fatigue.” In the absence of full shelter-in-place orders, travel was also reduced where restrictions on select businesses were introduced. For example, restrictions on entertainment, indoor dining, and indoor recreational activities corresponded to reductions in VMT of 3 to 4 percent while restrictions on retail and personal care facilities showed 13 percent lower traffic levels. VMT was also shown to vary based on the number of COVID case reports, as well as with respect to other characteristics, including median household income, political leanings, and how rural the county was in nature.


2003 ◽  
Vol 35 (2) ◽  
pp. 119-125 ◽  
Author(s):  
B. Fauroux ◽  
C. Boffa ◽  
I. Desguerre ◽  
B. Estournet ◽  
H. Trang ◽  
...  

BMJ ◽  
1989 ◽  
Vol 298 (6688) ◽  
pp. 1643-1643
Author(s):  
J W H Watt ◽  
K R Krishnan

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Juan Wang ◽  
Dan Norbäck

Abstract Background Poor acoustic conditions at home can have negative health impact. The aim was to investigate home environment factors and medical symptoms associated with noise disturbance. Methods All adults (≥18 y) registered in selected apartments in Sweden were invited to participate in a questionnaire survey including medical questions and personal factors. Totally 5775 adults participated (response rate 46%). Information on home environment was obtained through an indoor environment questionnaire. Two-level logistic regression models (individual, municipality) were performed to estimate associations. Results Totally 11.9% reported noise disturbance in general at home. Noise disturbance from voice/radio/TV/music/similar sounds from neighbours (13.2%), scraping sound/footsteps/thumping from neighbours (16.5%) and road traffic (16.1%) were common. Younger age and smoking were related to more noise disturbance and more medical symptoms. Noise disturbance was related to tiredness, headache and difficulty concentrating (OR = 1.70–8.19). Renting the apartment (OR = 2.53) and living above ground floor (OR = 1.37) were related to more noise disturbance in general. Living in newer buildings (constructed from 1986 to 2005) was related to less noise disturbance in general (OR = 0.40–0.59). A warmer climate (OR = 1.95), higher municipality population density (OR = 1.24), a longer living time (OR = 1.34), construction year (1961–1975) (OR = 2.42), renting (OR = 1.80–2.32), living above ground floor (OR = 1.45) and having a bathroom fan (OR = 1.84) were associated with increased noise disturbance from neighbours. Factors associated with increased noise disturbance from installations or ventilation/fans/heat pumps included a warmer climate, higher municipality population density, construction year (1961–1995), renting and any mechanical ventilation. Higher municipality population density, construction year (especially 1961–1985) and renting were associated with more noise disturbance from traffic (OR = 1.77–3.92). Renting the apartment (OR = 1.73) and living above ground floor (OR = 1.60) were related to more severe traffic noise disturbances. Noise disturbance in general was partly a mediator of the effects of old buildings, renting the apartment and lack of mechanical ventilation on medical symptoms (% of total effect mediated by noise disturbance: 19–44.8%). Conclusions Noise disturbance can be associated medical symptoms. Younger age, smoking, a warmer climate, higher municipality population density and different building factors (e.g. renting the apartment, construction period 1961–1985) can be associated with noise disturbance.


2021 ◽  
Author(s):  
CC Pavani ◽  
LR Vieira ◽  
TC Schott ◽  
D Sundfeld ◽  
NIP Pini ◽  
...  

SUMMARY Adequate removal of residual bonded materials from the enamel surface after orthodontic bracket debonding is critical, since any remaining composite may compromise enamel surface morphology and esthetics. The following clinical case reports present the association of at-home dental bleaching using 10% carbamide peroxide and the removal of residual bonded material using a super fine, tapered diamond bur followed by the use of an enamel microabrasion product after orthodontic bracket debonding. The proposed treatment considerably improved the esthetics and successfully removed the grooves created during the removal of the bonding composite, resulting in a smooth enamel surface.


PEDIATRICS ◽  
1989 ◽  
Vol 83 (6) ◽  
pp. 1023-1028
Author(s):  
Renato Stein ◽  
Gerard J. Canny ◽  
Desmond J. Bohn ◽  
Joseph J. Reisman ◽  
Henry Levison

The management of children with severe acute asthma who required admission to the intensive care (ICU) of this hospital during 1982 to 1988 was reviewed retrospectively. A total of 89 children were admitted to the ICU on 125 occasions. During the study period, 24% of the patients were admitted to the ICU on more than one occasion. Prior to admission to this hospital, patients had been symptomatic for a mean of 48 hours. Although all patients had received bronchodilators before admission to hospital, only 23% of patients had received oral corticosteroids. According to initial arterial blood gas values determined in the ICU, 77% of the patients had hypercapnia (PaCO2 >45 mm Hg). The pharmacologic agents used in the ICU included nebulized β2agonists (100% of admissions), theophylline (99%), steroids (94%), nebulized ipratropium bromide (10%), IV albuterol (38%), and IV isoproterenol (10%). Mechanical ventilation was necessary in 33% of admissions; the mean duration of ventilation was 32 hours. Ten patients had pneumothorax; in six cases, these were related to mechanical ventilation. Three of the patients who received mechanical ventilation died, representing a mortality of 7.5%. In each of these patients, sudden, severe asthma episodes had developed at home, resulting in respiratory arrest. They had evidence of hypoxic encephalopathy at the time of admission to the ICU and eventually were declared brain dead. It was concluded that delay in seeking medical care and underuse of oral corticosteroids at home may have contributed to the need for ICU admission. The mortality and morbidity for children with severe asthma who require ICU admissions are small, provided that bronchodilators and IV steroids are used optimally and that patients who require mechanical ventilation are carefully selected.


2020 ◽  
Vol 24 (4) ◽  
pp. 287-292
Author(s):  
Serena Tomasino ◽  
Rosa Sassanelli ◽  
Corrado Marescalco ◽  
Francesco Meroi ◽  
Luigi Vetrugno ◽  
...  

At the end of 2019, a novel coronavirus (COVID-19) was identified as the cause of a cluster of pneumonia cases, with high needs of mechanical ventilation in critically ill patients. It is still unclear whether different types of COVID-19 pneumonia require different ventilator strategies. With electrical impedance tomography (EIT) we evaluated, in real time and bedside, the distribution of ventilation in the different pulmonary regions before, during, and after pronation in COVID-19 respiratory failure. We present a brief literature review of EIT in non-COVID-19 patients and a report of 2 COVID-19 patients: one that did not respond well and another one that improved during and after pronation. EIT might be a useful tool to decide whether prone positioning should or should not be used in COVID-19 pneumonia.


CHEST Journal ◽  
2020 ◽  
Vol 158 (6) ◽  
pp. 2493-2501 ◽  
Author(s):  
Ries J.M. van den Biggelaar ◽  
Anda Hazenberg ◽  
Nicolle A.M. Cobben ◽  
Michael A. Gaytant ◽  
Karin M. Vermeulen ◽  
...  

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