Study on the Device "Gondola" for Motor Rehabilitation in Parkinson's Disease

Author(s):  
2013 ◽  
Vol 28 (1) ◽  
pp. 85-95 ◽  
Author(s):  
Emily K. Plowman ◽  
Nicholas Maling ◽  
Nagheme J. Thomas ◽  
Stephen C. Fowler ◽  
Jeffrey A. Kleim

2016 ◽  
Vol 94 (4) ◽  
pp. 455-461 ◽  
Author(s):  
Francesco Angelucci ◽  
Jacopo Piermaria ◽  
Francesca Gelfo ◽  
Jacob Shofany ◽  
Marco Tramontano ◽  
...  

Increasing evidence suggests that motor rehabilitation may delay Parkinson’s disease (PD) progression. Moreover, parallel treatments in animals up-regulate brain-derived neurotrophic factor (BDNF). Thus, we investigated the effect of a motor rehabilitation protocol on PD symptoms and BDNF serum levels. Motor rehabilitation training consisted of a cycle of 20 days/month of physiotherapy divided in 3 daily sessions. Clinical data were collected at the beginning, at the end, and at 90 days follow-up. BDNF serum levels were detected by ELISA at 0, 7, 14, 21, 30, and 90 days. The follow-up period had a duration of 60 days (T30–T90). The results showed that at the end of the treatment (day 30), an improvement in extrapyramidal signs (UPDRS III; UPDRS III – Gait and Balance items), motor (6 Minute Walking Test), and daily living activities (UPDRS II; PDQ-39) was observed. BDNF levels were increased at day 7 as compared with baseline. After that, no changes in BDNF were observed during the treatment and in the successive follow-up. This study demonstrates that motor rehabilitation training is able to ameliorate PD symptoms and to increase temporarily BDNF serum levels. The latter effect may potentially contribute to the therapeutic action.


Author(s):  
Pablo Arias ◽  
Javier Cudeiro

In the last years the role of sensory rhythmic stimulation (SRS) on motor rehabilitation in PD has become a new line of interest for researches and therapists given the promising results reported in scientific literature. This kind of strategies present a whole range of features which make it very appealing for its daily use, namely, they are easy to use, they have not distorting side-effects, and, chiefly, their effectiveness have been reported either in presence as in absence of antiparkinsonian medication.


2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Francesca Baglio ◽  
Alice Pirastru ◽  
Niels Bergsland ◽  
Marta Cazzoli ◽  
Eleonora Tavazzi

Abstract Parkinson’s disease (PD) is the second most common neurological disease affecting the elderly population. Pharmacological and surgical interventions usually employed for PD treatment show transient effectiveness and are associated with the insurgence of side effects. Therefore, motor rehabilitation has been proposed as a promising supplement in the treatment of PD, reducing the global burden of the disease and improving patients quality of life. The present systematic review aimed to critically analyse the literature concerning MRI markers of brain functional and structural response to motor rehabilitation in PD. Fourteen out of 1313 studies were selected according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Despite the limited number of retrieved studies coupled with their heterogeneity prevent ultimate conclusions from being drawn, motor rehabilitation seems to have beneficial effects on PD as measured both with clinical outcomes and MRI derived indices. Interestingly, consistent results seem to indicate that motor rehabilitation acts via a dual mechanism of strengthening cortico-subcortical pathways, restoring movements automaticity, or activating compensatory networks such as the fronto-parietal one. The employment of more advanced and quantitative MRI methods is warranted to establish and validate standardized metrics capable of reliably determining the changes induced by rehabilitative intervention.


2016 ◽  
Vol 21 (3) ◽  
pp. 1650-1658 ◽  
Author(s):  
Hassan Mohammadi-Abdar ◽  
Angela L. Ridgel ◽  
Fred M. Discenzo ◽  
Kenneth A. Loparo

2007 ◽  
Vol 26 (3) ◽  
pp. 452-462 ◽  
Author(s):  
A. Peppe ◽  
C. Chiavalon ◽  
P. Pasqualetti ◽  
D. Crovato ◽  
C. Caltagirone

2017 ◽  
Vol 56 (02) ◽  
pp. 138-144 ◽  
Author(s):  
Sergio Albiol-Pérez ◽  
José-Antonio Gil-Gómez ◽  
Maria-Teresa Muñoz-Tomás ◽  
Hermenegildo Gil-Gómez ◽  
Raquel Vial-Escolano ◽  
...  

SummaryObjectives: Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor clinical alterations among others. Postural problems have serious consequences for patients, not only limiting their daily life but also increasing some risks, like the risk of fall. Inadequate postural control and postural instability is a major problem in PD patients. A Virtual Motor Rehabilitation System (VMR) has been tested in patients with PD in the intervention period. Our purpose was to analyze the evolution of the spatial postural control during the intervention period, to see if there are any changes caused precisely by this intervention.Methods: Ten people with PD carried out 15 virtual rehabilitation sessions. We tested a groundbreaking system based on Virtual Motor Rehabilitation in two periods of time (baseline evaluation and final evaluation). In the training sessions, the participants performed a customizable treatment using a low-cost system, the Active Balance Rehabilitation system (ABAR). We stored the pressure performed by the participants every five hundredths of a second, and we analyzed the patients’ pressure when they maintained their body on the left, on the right, and in the center in sitting position. Our system was able to measure postural control in every patient in each of the virtual rehabilitation sessions.Results: There are no significant differences in the performance of postural control in any of the positions evaluated throughout the sessions. Moreover, the results show a trend to an improvement in all positions. This improvement is especially remarkable in the left/right positions, which are the most important positions in order to avoid problems such as the risk of fall. With regard to the suitability of the ABAR system, we have found outstanding results in enjoyment, success, clarity, and helpfulness.Conclusions: Although PD is a progressive neurodegenerative disorder, the results demonstrate that patients with PD maintain or even improve their postural control in all positions. We think that the main factor influencing these results is that patients use more of their available cognitive processing to improve their postural control. The ABAR system allows us to make this assumption because the system requires the continuous attention of patients, promoting cognitive processing.


2016 ◽  
Vol 24 (11) ◽  
pp. 1254-1264 ◽  
Author(s):  
Hassan Mohammadi-Abdar ◽  
Angela L. Ridgel ◽  
Fred M. Discenzo ◽  
Robert S. Phillips ◽  
Benjamin L. Walter ◽  
...  

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