Respiratory Function, Exercise Capacity and Peripheral Muscle Strength Among Patients With CF, PCD and Healthy Children

2019 ◽  
Author(s):  
Keyword(s):  
Muscle Strength ◽  
Exercise Capacity ◽  
Respiratory Function ◽  
Healthy Children ◽  
Peripheral Muscle

scholarly journals Exercise Capacity in Prepubertal Children with Cystic Fibrosis

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Emma Kilbride ◽  
John Widger ◽  
Juliette Hussey ◽  
Basil El Nazir ◽  
Peter Greally
Keyword(s):  
Cystic Fibrosis ◽  
Muscle Strength ◽  
Lung Function ◽  
Nutritional Status ◽  
Aerobic Exercise ◽  
Exercise Capacity ◽  
Healthy Children ◽  
Prepubertal Children ◽  
Peripheral Muscle ◽  
Control Versus

Background. Patients with cystic fibrosis (CF) are observed to have diminished lung function, nutritional status, and aerobic exercise capacity. All three parameters are related to prognosis and survival. However, there is little information regarding these parameters in prepubertal patients. Methods. Our study groups consisted of sixteen patients with CF (7 girls) and 99 healthy volunteers (52 girls). Subjects performed spirometry and a progressive exercise test to exhaustion on a cycle ergometer. Leg muscle strength was measured using an isokinetic dynamometer. Physical activity was examined using the modifiable activity questionnaire and accelerometer. Results. Nutritional status was similar between groups (BMI—boys control versus CF 18.5 versus 17.9, girls control versus CF 19.5 versus 17.4). Girls with CF were significantly smaller and lighter than controls. Lung function was significantly reduced in CF groups (FEV1—boys control versus CF 91% versus 84%, girls control versus CF 90% versus 82%). Patients with CF were as active and as fit as their healthy controls. Conclusion. In this group of prepubertal children with CF, nutritional status was comparable to healthy children of the same age. Their aerobic exercise tolerance and peripheral muscle strength were also relatively well preserved despite significantly lower lung function.

scholarly journals Beneficial Effect of Water-Based Exercise Training on Exercise Capacity in COPD Patients—a Pilot Study

2021 ◽  
Vol 2 ◽  
Author(s):  
Noppawan Charususin ◽  
Thiti Sricharoenchai ◽  
Karan Pongpanit ◽  
Kornanong Yuenyongchaiwat ◽  
Phuwarin Namdaeng ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Exercise Training ◽  
Exercise Capacity ◽  
Respiratory Function ◽  
Intervention Group ◽  
Exercise Program ◽  
Walk Test ◽  
Peripheral Muscle ◽  
Water Based ◽  
Balance Ability

Background: Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable condition, characterized by persistent airflow limitation. Exercise training is a core component of pulmonary rehabilitation in people with COPD. Water-based exercise has been studied, but it remains unclear whether water-based exercise program leads to the improvement in respiratory function, muscle strength, balance ability, and exercise capacity. We aim to study the effect of an 8-week water-based exercise program on respiratory function, muscle strength, balance ability, and exercise capacity in people with COPD.Methods: Fourteen stable COPD participants (FEV1 56.8 ± 24.6%pred) were recruited and randomized into a water-based exercise or a land-based exercise group. Both groups were trained for 8 weeks, two sessions per week. Pulmonary function, respiratory muscle strength, peripheral muscle strength, balance ability, exercise capacity [6-min walking test (6MWT), incremental shuttle walk test (ISWT), and endurance shuttle walk test (ESWT)] were assessed at baseline and at the end of the program. ANCOVA was used to conduct between-group comparisons of outcomes after adjusting for pre-intervention values.Results: Baseline characteristics of participants were not significantly different between the two groups (p ≥ 0.05). After the 8-week training program, participants in the intervention group achieved larger gains in ESWT (Δ663.4 ± 279.5 vs. Δ45.4 ± 93.2 s, p = 0.001). In addition, maximal inspiratory pressure (MIP) was significantly increased more in the intervention group (Δ11.1 ± 7.8 vs. Δ1.1 ± 5.7 cmH2O, p = 0.026). However, no significant differences in pulmonary function, peripheral muscle strength, balance ability variables, 6MWD (p = 0.248), and ISWT (p = 0.506) were observed between the two groups.Conclusions: The water-based exercise program could be recommended to the COPD rehabilitation program for improving the endurance exercise capacity and inspiratory muscle strength.Clinical Trial Registration:www.thaiclinicaltrials.org, identifier: TCTR20210125005.

P296 Association of peripheral muscle strength with exercise capacity and use of antibiotics in patients with cystic fibrosis

2020 ◽  
Vol 19 ◽  
pp. S139
Author(s):  
N. Evangelista Campos ◽  
F.M. Vendrusculo ◽  
M.F. Gheller ◽  
I. Silveira de Almeida ◽  
N. Acosta Becker ◽  
...  
Keyword(s):  
Cystic Fibrosis ◽  
Muscle Strength ◽  
Exercise Capacity ◽  
Peripheral Muscle

scholarly journals Is the peripheral muscle weakness a limitation to exercise on chronic kidney disease?

2020 ◽  
Vol 33 ◽  
Author(s):  
Davi de Souza Francisco ◽  
Ana Karla Vieira Brüggemann ◽  
Tarcila Dal Pont ◽  
Mariana Nunes Lúcio ◽  
Elaine Paulin
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Muscle Strength ◽  
Exercise Capacity ◽  
Muscle Weakness ◽  
Lower Limb ◽  
Public Health Problem ◽  
Healthy Individuals ◽  
Peripheral Muscle ◽  
Left Limb

Abstract Introduction: Chronic kidney disease (CKD) is a global public health problem with systemic repercussions, compromising muscle function and making patients less exercise tolerant. Objective: To verify the contribution of peripheral muscle strength in the exercise capacity of patients in hemodialysis (HD), as well as to compare peripheral muscle strength and exercise capacity between renal patients and healthy individuals. Method: 50 patients with chronic kidney disease (CKD) who performed HD and 13 healthy subjects underwent anthropometric evaluation, evaluation of peripheral muscle strength, pulmonary function test and exercise capacity assessment. Results: Simple linear regression indicated that the peripheral muscle strength contributed 41.4% to the distance walked in the six-minute walk test (R2 0.414; p < 0.001), showing that for every 1 Kgf reduced in the right lower limb the patient it stops walking 0.5m while for every 1 Kgf reduced in the lower left limb the patient stops walking 0.8m. In addition, it was observed that patients with CKD had a reduction in right lower limb muscle strength (129.44 ± 48.05 vs. 169.36 ± 44.30, p = 0.002), left (136.12 ± 52, 08 vs 168.40 ± 43.35, p = 0.01) and exercise capacity (421.20 ± 98.07 vs. 611.28 ± 80.91, p < 0.001) when compared to healthy pairs. Conclusion: Peripheral muscle weakness is an important limiting factor for exercise in CKD and patients on HD experience a decline in peripheral muscle strength and exercise capacity when compared to healthy individuals.

scholarly journals The impact of muscle strength on exercise capacity and symptoms

2020 ◽  
Vol 6 (4) ◽  
pp. 00089-2020
Author(s):  
Mohammed Abdul Malik Farooqi ◽  
Kieran Killian ◽  
Imran Satia
Keyword(s):  
Muscle Strength ◽  
Exercise Capacity ◽  
Functional Limitation ◽  
Cardiopulmonary Exercise Testing ◽  
Multiple Linear Regression Model ◽  
Quadriceps Strength ◽  
Exercise Intolerance ◽  
Maximal Power Output ◽  
Peripheral Muscle ◽  
The Impact

The capacity to exercise is a major contributor to functional limitation and is accompanied by increased morbidity and mortality. What are the most important physiological contributors to exercise capacity?Cross-sectional data from consecutive patients referred to the McMaster University Medical Centre exercise laboratory for incremental cardiopulmonary exercise testing from 1988 to 2012 were analysed. Exercise capacity was determined by maximal power output (MPO) in kpm·min−1. The contributions of quadriceps strength (maximal peak force in kg using maximal dynamic voluntary contractions against hydraulic resistance), inspiratory muscle strength (determined using maximal inspiratory pressure (MIP)), maximal breathing capacity (MBC) and gas exchange (carbon monoxide transfer coefficient (KCO)) were determined using regression coefficients in a multiple linear regression model. Dyspnoea and leg fatigue were measured using the modified Borg scale. Contributors to dyspnoea and leg fatigue were assessed using nonlinear regression.A total of 36 389 patients were included (60% male, mean±sd age 53±18 years). Mean±sd MPO, quadriceps strength and MIP achieved were 792±333 kpm·min−1, 46±18 kg and 75±31 cmH2O, respectively. MIP and quadriceps strength accounted for over half the variation in MPO (R2=0.57). Quadriceps strength was a stronger predictor of MPO (standardised regression coefficient, β±se 0.37±0.005) than MBC (β±se 0.16±0.005) and KCO (β±se 0.16±0.004), when adjusted for age, sex, height and weight. The effort required to cycle and breathe at any given power intensified systematically as both respiratory and peripheral muscle strength declined.Muscle weakness causes exercise intolerance and should be routinely assessed in patients presenting with fatigue and dyspnoea, and those with functional limitation both in the presence or absence of disease.

Exercise capacity, peripheral muscle strength, and balance are related in primary ciliary dyskinesia

2021 ◽  
Author(s):  
Hazal Sonbahar Ulu ◽  
Aslihan Cakmak ◽  
Deniz Inal Ince ◽  
Melda Saglam ◽  
Naciye Vardar Yagli ◽  
...  
Keyword(s):  
Muscle Strength ◽  
Exercise Capacity ◽  
Primary Ciliary Dyskinesia ◽  
Peripheral Muscle ◽  
Ciliary Dyskinesia
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