scholarly journals Post-hospital Mortality Forecast in Young and Middle-Aged Patients with Myocardial Infarction

Doctor Ru ◽  
2020 ◽  
Vol 19 (5) ◽  
pp. 24-29
Author(s):  
E.A. Shishkina ◽  
◽  
O.V. Khlynova ◽  
A.B. Cheremnykh ◽  
◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Hospital Mortality ◽  
Middle Aged ◽  
Aged Patients ◽  
Mortality Forecast

scholarly journals Sex Differences in Perceived Stress and Early Recovery in Young and Middle-Aged Patients With Acute Myocardial Infarction

Circulation ◽  
2015 ◽  
Vol 131 (7) ◽  
pp. 614-623 ◽  
Author(s):  
Xiao Xu ◽  
Haikun Bao ◽  
Kelly Strait ◽  
John A. Spertus ◽  
Judith H. Lichtman ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Sex Differences ◽  
Perceived Stress ◽  
Middle Aged ◽  
Early Recovery ◽  
Aged Patients

scholarly journals Racial Disparities in Adverse Cardiovascular Outcomes After a Myocardial Infarction in Young or Middle‐Aged Patients

2021 ◽  
Author(s):  
Mariana Garcia ◽  
Zakaria Almuwaqqat ◽  
Kasra Moazzami ◽  
An Young ◽  
Bruno B. Lima ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Coronary Artery Disease ◽  
Socioeconomic Status ◽  
Coronary Artery ◽  
Racial Disparities ◽  
Middle Aged ◽  
Aged Patients ◽  
Black Patients ◽  
Artery Disease

Background Black patients tend to develop coronary artery disease at a younger age than other groups. Previous data on racial disparities in outcomes of myocardial infarction (MI) have been inconsistent and limited to older populations. Our objective was to investigate racial differences in the outcome of MI among young and middle‐aged patients and the role played by socioeconomic, psychosocial, and clinical differences. Methods and Results We studied 313 participants (65% non‐Hispanic Black) <61 years old hospitalized for confirmed type 1 MI at Emory‐affiliated hospitals and followed them for 5 years. We used Cox proportional‐hazard models to estimate the association of race with a composite end point of recurrent MI, stroke, heart failure, or cardiovascular death after adjusting for demographic, socioeceonomic status, psychological, and clinical risk factors. The mean age was 50 years, and 50% were women. Compared with non‐Black patients, Black patients had lower socioeconomic status and more clinical and psychosocial risk factors but less angiographic coronary artery disease. The 5‐year incidence of cardiovascular events was higher in Black (35%) compared to non‐Black patients (19%): hazard ratio (HR) 2.1, 95% CI, 1.3 to 3.6. Adjustment for socioeconomic status weakened the association (HR 1.3, 95% CI, 0.8–2.4) more than adjustment for clinical and psychological risk factors. A lower income explained 46% of the race‐related disparity in outcome. Conclusions Among young and middle‐aged adult survivors of an MI, Black patients have a 2‐fold higher risk of adverse outcomes, which is largely driven by upstream socioeconomic factors rather than downstream psychological and clinical risk factors.

T786C eNOS polymorphism as risk factor for recurrent myocardial infarction in young and middleaged patients

2020 ◽  
pp. 17-21
Author(s):  
E. A. Shishkina ◽  
O. V. Khlynova ◽  
A. V. Tuev ◽  
A. V. Krivtsov
Keyword(s):  
Myocardial Infarction ◽  
Risk Factor ◽  
Coronary Intervention ◽  
Middle Aged ◽  
Aged Patients ◽  
Recurrent Myocardial Infarction ◽  
Enos Polymorphism ◽  
Acute Mi ◽  
Oxide Synthase ◽  
Endothelial Nitric Oxide

Objective. To determine the possible role of the endothelial nitric oxide synthase (eNOS) polymorphism T786C (rs 2070744) in developing of recurrent myocardial infarction (MI) in young and middle-aged patients. Materials and methods. 114 patients with acute MI treated with percutaneous coronary intervention and thrombolysis that were admitted to Clinical cardiologic dispensary (Perm city, Russia) were enrolled into a study. Among them there were 28 patients with recurrent MI. The eNOS T786C polymorphism were determined by real-time PCR. Results. In T786C polymorphism of eNOS, compared with the T/T genotype, it was determined that those with T/C has 2,27 fold (95 % CI: 1.01–5.49), and those with the CC genotype has 2.22 times (95 % CI: 1.30–8.53) (p = 0.034) greater risk of developing recurrent MI. Patients with severe coronary arteries atherosclerosis more frequently had eNOS T786C polymorphism of T/C genotype (OR = 4,67; 95 % CI: 1,38–15,37; p = 0,031). Conclusion. The eNOS T786C variants could be evaluated as recurrent MI risk factor in young and middle-aged patients.

Smoking as an independent risk factor for myocardial infarction or stroke in type 2 diabetes: a report from the Swedish National Diabetes Register

2009 ◽  
Vol 16 (4) ◽  
pp. 506-512 ◽  
Author(s):  
Peter M. Nilsson ◽  
Jan Cederholm ◽  
Katarina Eeg-Olofsson ◽  
Björn Eliasson ◽  
Björn Zethelius ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Type 2 Diabetes ◽  
Risk Factor ◽  
Total Mortality ◽  
Lipid Lowering ◽  
Diabetic Patients ◽  
Middle Aged ◽  
Aged Patients ◽  
Diabetes Register

Background Few earlier studies have analysed smoking as a risk factor for myocardial infarction (MI) or stroke in type 2 diabetic patients. Design and methods A longitudinal study involved 13 087 female and male patients with type 2 diabetes from the Swedish National Diabetes Register with no previous MI or stroke at baseline, aged 30–74 years, and with data available for all analysed variables, followed up for mean 5.7 years. Results Adjusted hazard ratios (HRs) for smoking and first-incident fatal/nonfatal MI, stroke and total mortality were 1.7 [95% confidence interval (CI): 1.4–2.0; P < 0.001], 1.3 (95% CI: 1.1–1.6; P = 0.006) and 1.8 (95% CI: 1.5–2.2; P < 0.001), respectively, by Cox regression analysis, adjusted for age, sex, diabetes duration, hypoglycaemic treatment, haemoglobin A1c, blood pressure, body mass index, microalbuminuria, antihypertensive and lipid-lowering drugs. Adjusted HR was higher for fatal MI, 2.1 (95% CI: 1.7–2.7; P < 0.001), than for nonfatal MI, 1.4 (95% CI: 1.2–1.7; P < 0.001). The highest HRs were observed in more frequently smoking (22%), middle-aged patients (age < 60 years) for fatal/nonfatal MI, 2.3 (95% CI: 1.8–3.1; P < 0.001) and for total mortality, 2.5 (95% CI: 1.6–3.8, P < 0.001), whereas lower HRs were observed in older and less smoking patients. With predicted cessation of smoking in patients aged below 60 years, 24% (95% CI: 15–33%) of cases of fatal/nonfatal MI and 24% (11–37%) of cases of total mortality may have been prevented. Conclusion The risk for MI and total mortality associated with smoking is high in type 2 diabetes, especially in more frequently smoking, middle-aged patients, and was higher for MI than for stroke, and also higher for fatal than for nonfatal events. Smoking cessation would strongly affect risk reduction.

scholarly journals The Relationship among Death Anxiety, Knowledge and Attitudes toward Advance Directives in Middle-Aged Patients with Acute Myocardial Infarction

2021 ◽  
Vol 23 (3) ◽  
pp. 226-238
Author(s):  
Mi Young Suh ◽  
Jeong Sun Kim
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Advance Directives ◽  
Death Anxiety ◽  
Pearson Correlation ◽  
Average Score ◽  
Middle Aged ◽  
Aged Patients ◽  
Knowledge And Attitudes ◽  
The Relationship

Purpose: This study aimed to identify the relationship between death anxiety, knowledge, and attitudes toward advance directives in middle-aged patients with acute myocardial infarction.Methods: Data were collected through a survey of 142 middle-aged adults from August 27th to October 4th, 2019 in G city. Data analysis was performed using descriptive statistics, t-test, one-way ANOVA, Scheffé test, and Pearson correlation coefficient.Results: The average score of participants’ death anxiety and attitudes toward advance directives was 44.14± 6.71 and 43.61±3.53, respectively, and the average correct rate in knowledge of advance directives was 57.1%. Participants showed significant differences in death anxiety (F=3.75, p=.013), knowledge of advance directives (F=3.02, p=.033), and attitudes toward advance directives (t=2.31, p=.022) depending on the presence or absence of an object to discuss their health status. Also, there were significant differences in knowledge of advance directives (t=3.43, p=.001) and attitude toward advance directives (t=2.23, p=.027) depending on whether participants perceived the meaning of advance directives. There were positive correlations (r=.38, p<.001) between knowledge of advance directives and attitudes toward advance directives in middle-aged patients with acute myocardial infarction.Conclusion: Active information-provision and promotional strategies are needed to enhance a correct understanding of advance directives for middle-aged acute myocardial infarction patients with a high probability of sudden death to recognize the need for an advance directive and reinforce a positive attitude.

scholarly journals Assessment of Acute Stress Disorder of Young and Middle-Aged Patients With Acute Myocardial Infarction And Analysis of The Influencing Factors

2021 ◽  
Author(s):  
Minjuan Wu ◽  
Wang Wenqin ◽  
Zhang Xingwei ◽  
Li Junhua
Keyword(s):  
Myocardial Infarction ◽  
Social Support ◽  
Acute Myocardial Infarction ◽  
Cardiac Rehabilitation ◽  
Stress Disorder ◽  
Acute Stress ◽  
Acute Stress Disorder ◽  
Middle Aged ◽  
Aged Patients ◽  
Aged People

Abstract Background: Young and middle-aged people are considered a vulnerable group to experience acute stress disorder (ASD) after acute myocardial infarction (AMI). This study aims to explore influencing factors to ASD in young and middle-aged groups.Methods: 190 patients of 18–60 years of age with acute myocardial infarction were enrolled in this study. We assessed the association between ASD and demographic data, adult attachment, and social support.Results: A total of 190 young and middle-aged people were investigated in this study. Among them, 65 cases were positive for acute stress disorder, with a positive rate of 34.21%. Multivariate stepwise regression showed that attachment-related anxiety, distribution of criminal vessels, perceived support, complications, and attachment-related avoidance are the main factors affecting acute stress disorder of young and middle-aged patients with AMI.Conclusions: The incidence of acute stress disorder in young and middle-aged patients with AMI is high. We should strengthen social support and pay attention to the psychological state of patients in the process of follow-up cardiac rehabilitation to improve their ability to deal with acute stress events and actively participate in postoperative cardiac rehabilitation.

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