scholarly journals FEATURES OF THE REACTION OF THE HEART RATE OF LABORATORY ANIMALS EXPOSED TO VARIOUS MODES OF MOTOR ACTIVITY DURING ADMINISTRATION β, α1 AND α2-ADRENO STIMULANTS

2021 ◽  
Vol 247 (3) ◽  
pp. 306-311
Author(s):  
A.V. Shigapova ◽  
◽  
I.H. Vakhitov ◽  
R.H. Ravilov ◽  
A.H. Volkov ◽  
...  
Keyword(s):  
Heart Rate ◽  
Motor Activity ◽  
Heart Rate Response ◽  
Laboratory Animals ◽  
Muscle Training ◽  
High Level ◽  
First Time

For the first time, studies have been conducted to study the features of the heart rate response of laboratory animals exposed to various modes of motor activity when administered β, α1 and α2-adrenostimulants. It was found that in animal’s subject to a regime of limited motor activity, i.e. hypokinesia, the heart rate response to the introduction of β and α1-adreno stimulators remains at a high level. It was revealed that the regime of systematic muscle training significantly contributes to the reduction of this reaction. It was found that in the process of systematic muscle training of animals, there is also a significant decrease in the heart rate response to the introduction of an α2-adrenostimulator. The hypokinesia mode keeps this reaction at a high level.

scholarly journals THE ROLE OF β, α1 AND α2-ADRENO RECEPTORS IN THE REGULATION OF THE HEART RATE OF LABORATORY ANIMALS EXPOSED TO VARIOUS MODES OF MOTOR ACTIVITY

2021 ◽  
Vol 248 (4) ◽  
pp. 291-296
Author(s):  
A.V. Shigapova ◽  
◽  
I.Kh. Vakhitov ◽  
R.S. Safin ◽  
I.R. Ibatullin ◽  
...  
Keyword(s):  
Heart Rate ◽  
Motor Activity ◽  
Heart Rate Response ◽  
Laboratory Animals ◽  
Initial Reaction ◽  
Muscle Training ◽  
Pronounced Decrease ◽  
Motor Mode ◽  
First Time

For the first time, studies were conducted to study the features of the heart rate response of laboratory animals exposed to various modes of motor activity when administered with β, α1 and α2-blockers. It was found that in all the experimental groups of animals studied, a decrease in the heart rate response was observed in the first week after the introduction of β, α1 and α2-adreno blockers. It was revealed that the initial reaction of the heart rate on the introduction of β, α1 and α2-blockers depends on the level of motor activity of laboratory animals. It was found that the most pronounced decrease in the heart rate response to the introduction of different subtypes of adreno-blockers is observed in the group of animals with limited motor activity. At the same time, the smallest decrease in the heart rate response occurs in the group of animals subject to enhanced motor mode. It was revealed that in the group of experimental animals, during further muscle training, by the end of the fourth week, there was a less pronounced decrease in the heart rate response to the administration of β, α1 and α2-adreno blockers. It was found that in a group of animals subject to a regime of limited motor activity, by the end of the fourth week of hypokinesia, the most pronounced decrease in the heart rate response to the introduction of β, α1-targeted blockers occurs.

scholarly journals THE EFFECT OF A TRAUMATIC BRAIN INJURY ON CHANGES IN THE HEART RATE OF RATS SUBJECT TO VARIOUS MODES OF MOTOR ACTIVITY

2021 ◽  
Vol 10 (4) ◽  
pp. 3310-3315
Author(s):  
Bulat Ildarovich Vakhitov
Keyword(s):  
Traumatic Brain Injury ◽  
Heart Rate ◽  
Brain Injury ◽  
Motor Activity ◽  
Heart Rate Response ◽  
Age Groups ◽  
Preschool Age ◽  
Pronounced Increase ◽  
Age Related ◽  
First Time

For the first time, studies have been conducted to study the reaction of animal heart rate to various modes of motor activity after a traumatic brain injury. It was revealed that on the first day after modeling an open head injury in rats of all age groups, a pronounced increase in heart rate was observed. In this case, the smallest heart rate response to brain injury is observed in animals of immature age. It was found that the implementation of systematic dynamic exercises by animals of mature and preschool age after modeling a craniocerebral injury contributes to a significant decrease in heart rate. A more pronounced formation of training bradycardia is observed in immature animals. It was revealed that limiting motor activity and performing isometric exercises after a traumatic brain injury maintain heart rate at an increased level in all age groups of animals and significantly inhibits the natural, age-related decrease in heart rate in immature animals.

Maternal blood pressure and heart rate response to pelvic floor muscle training during pregnancy

2014 ◽  
Vol 93 (7) ◽  
pp. 678-683 ◽  
Author(s):  
Cristine H. Ferreira ◽  
Luciane M.V. Naldoni ◽  
Juliana dos Santos Ribeiro ◽  
Maria Cristina C.C. Meirelles ◽  
Ricardo de Carvalho Cavalli ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Pelvic Floor ◽  
Heart Rate Response ◽  
Pelvic Floor Muscle Training ◽  
Pelvic Floor Muscle ◽  
Maternal Blood ◽  
Muscle Training ◽  
Maternal Blood Pressure

scholarly journals Technical Analysis and Heart Rate Response of Minifootball Players During a Competitive Match

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Jamel Halouani ◽  
Thouraya Mhenni ◽  
Nejah Kacem ◽  
Khaled Trabelsi ◽  
Cain Clark ◽  
...  
Keyword(s):  
Heart Rate ◽  
Body Mass ◽  
High Intensity ◽  
Heart Rate Response ◽  
Rest Heart Rate ◽  
Technical Analysis ◽  
Technical Ability ◽  
High Level ◽  
Number Of Passes

Objectives: The aim of this study was to investigate the technical actions and heart rate response of amateur minifootball players during a competitive match. Methods: Ten male amateur minifootball players (age: 26.3 ± 4.2 years, height: 176 ± 7.4 cm and body mass: 78.9 ± 10 kg), from a First Division Tunisian team, participated in a match (2 × 25-min with 10 min rest). Heart rate was recorded during the whole time that participants spent on court. The minifootball match was recorded and analyzed for technical actions (i.e., data pertaining to passes, shots, actions, duels, fouls) using InStat. Results: Results showed that a minifootball match induced an intensity of 84.2% heart rate max (HRmax) (i.e., high intensity). The percentage of success in actions was 53.33 % and in shots was 36.54 %. A large number of passes (400 (290 successful)) and duels (210 (145 successful)) was found both in offensive and defensive phases. Conclusions: A minifootball match is of high intensity and requires a high level of physical and technical ability.

The discriminative control of a conditioned heart rate response.

1957 ◽  
Author(s):  
Philip J. Bersh ◽  
Joseph M. Notterman ◽  
William N. Schoenfeld
Keyword(s):  
Heart Rate ◽  
Heart Rate Response ◽  
Discriminative Control ◽  
Conditioned Heart Rate

Heart Rate Recovery Changes during Competition Period in High-Level Basketball Players

2018 ◽  
Vol 1 (80) ◽  
Author(s):  
Audrius Gocentas ◽  
Anatoli Landõr ◽  
Aleksandras Kriščiūnas
Keyword(s):  
Heart Rate ◽  
Heart Rate Recovery ◽  
Team Sports ◽  
Basketball Players ◽  
Coeffi Cients ◽  
Competition Period ◽  
Monitoring Training ◽  
Intense Training ◽  
High Level

Research background and hypothesis. Replete schedule of competitions and intense training are features of contemporary team sports. Athletes, especially the most involved ones, may not have enough time to recover. As a consequence, aggregated fatigue can manifest in some undesirable form and affect athlete’s performance and health.Research aim. The aim of this study was to evaluate the changes in heart rate recovery (HRR) and investigate possible relations with sport-specifi c measures of effi cacy in professional basketball players during competition season.Research methods. Eight male high-level basketball players (mean ± SD, body mass, 97.3 ± 11.33 kg; height 2.02 ± 0.067 m, and age 23 ± 3.12 years) were investigated. The same basketball specifi c exercise was replicated several times from September till April during the practice sessions in order to assess the personal trends of HRR. Heart rate monitoring was performed using POLAR TEAM SYSTEM. Investigated athletes were ranked retrospectively according to the total amount of minutes played and the coeffi cients of effi cacy. Research results. There were signifi cant differences in the trends of HRR between the investigated players. The most effective players showed decreasing trends of HRR in all cases of ranking.Discussion and conclusions. Research fi ndings have shown that the quality of heart rate recovery differs between basketball players of the same team and could be associated with sport-specifi c effi cacy and competition playing time.Keywords: adaptation, autonomic control, monitoring training.

A Confrontation between Two Doctrines: The Birth of Struggle for Hegemony in Hebrew Children's Literature during the 1930s and 1940s

2008 ◽  
Vol 1 (2) ◽  
pp. 139-155 ◽  
Author(s):  
YAEL DARR
Keyword(s):  
Children's Literature ◽  
Educational System ◽  
Single Channel ◽  
Children’S Literature ◽  
The Political ◽  
Literary Creation ◽  
History Of ◽  
High Level ◽  
First Time ◽  
Literary Quality

This article describes a crucial and fundamental stage in the transformation of Hebrew children's literature, during the late 1930s and 1940s, from a single channel of expression to a multi-layered polyphony of models and voices. It claims that for the first time in the history of Hebrew children's literature there took place a doctrinal confrontation between two groups of taste-makers. The article outlines the pedagogical and ideological designs of traditionalist Zionist educators, and suggests how these were challenged by a group of prominent writers of adult poetry, members of the Modernist movement. These writers, it is argued, advocated autonomous literary creation, and insisted on a high level of literary quality. Their intervention not only dramatically changed the repertoire of Hebrew children's literature, but also the rules of literary discourse. The article suggests that, through the Modernists’ polemical efforts, Hebrew children's literature was able to free itself from its position as an apparatus controlled by the political-educational system and to become a dynamic and multi-layered field.

Effect of human galanin on the response of circulating catecholamines to hypoglycemia in man

1995 ◽  
Vol 133 (6) ◽  
pp. 723-728 ◽  
Author(s):  
Ettore C degli Uberti ◽  
Maria R Ambrosio ◽  
Marta Bondanelli ◽  
Giorgio Transforini ◽  
Alberto Valentini ◽  
...  
Keyword(s):  
Heart Rate ◽  
Healthy Subjects ◽  
Sympathetic Nerve Activity ◽  
Heart Rate Response ◽  
Statistical Significance ◽  
Inhibitory Effect ◽  
Amino Acid Residues ◽  
Nerve Activity ◽  
Receptor Stimulation

degli Uberti EC, Ambrosio MR, Bondanelli M, Trasforini G, Valentini A, Rossi R, Margutti A, Campo M. Effect of human galanin on the response of circulating catecholamines to hypoglycemia in man. Eur J Endocrinol 1995;133:723–8. ISSN 0804–4643 Human galanin (hGAL) is a neuropeptide with 30 amino acid residues that has been found in the peripheral and central nervous system, where it often co-exists with catecholamines. In order to clarify the possible role of hGAL in the regulation of sympathoadrenomedullary function, the effect of a 60 min infusion of hGAL (80 pmol·kg−1 · min−1) on plasma epinephrine and norepinephrine responses to insulin-induced hypoglycemia in nine healthy subjects was investigated. Human GAL administration significantly reduced both the release of basal norepinephrine and the response to insulin-induced hypoglycemia, whereas it attenuated the epinephrine response by 26%, with the hGAL-induced decrease in epinephrine release failing to achieve statistical significance. Human GAL significantly increased the heart rate in resting conditions and clearly exaggerated the heart rate response to insulin-induced hypoglycemia, whereas it had no effect on the blood pressure. We conclude that GAL receptor stimulation exerts an inhibitory effect on basal and insulin-induced hypoglycemia-stimulated release of norepinephrine. These findings provide further evidence that GAL may modulate sympathetic nerve activity in man but that it does not play an important role in the regulation of adrenal medullary function. Ettore C degli Uberti, Chair of Endocrinology, University of Ferrara, Via Savonarola 9, I-44100 Ferrara, Italy

Synthesis of a silymarin-gold nanoparticle conjugate and analysis of its liver-protecting activity

2021 ◽  
Vol 22 ◽  
Author(s):  
Sergey Staroverov ◽  
Sergey Kozlov ◽  
Alexander Fomin ◽  
Konstantib Gabalov ◽  
Alexey Volkov ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Liver Disease ◽  
Carbon Tetrachloride ◽  
Glutathione Depletion ◽  
Laboratory Animals ◽  
Experimental Hepatitis ◽  
Acute Liver Disease ◽  
The Mean ◽  
Extent Of Damage ◽  
First Time

Background: The liver disease problem prompts investigators to search for new methods of liver treatment. Introduction: Silymarin (Sil) protects the liver by reducing the concentration of free radicals and the extent of damage to the cell membranes. A particularly interesting method to increase the bioavailability of Sil is to use synthesized gold nanoparticles (AuNPs) as reagents. The study considered whether it was possible to use the silymarin-AuNP conjugate as a potential liver-protecting drug. Method: AuNPs were conjugated to Sil and examine the liver-protecting activity of the conjugate. Experimental hepatitis and hepatocyte cytolysis after carbon tetrachloride actionwere used as a model system, and the experiments were conducted on laboratory animals. Result: For the first time, silymarin was conjugated to colloidal gold nanoparticles (AuNPs). Electron microscopy showed that the resultant preparations were monodisperse and that the mean conjugate diameter was 18–30 nm ± 0.5 nm (mean diameter of the native nanoparticles, 15 ± 0.5 nm). In experimental hepatitis in mice, conjugate administration interfered with glutathione depletion in hepatocytes in response to carbon tetrachloride was conducive to an increase in energy metabolism, and stimulated the monocyte–macrophage function of the liver. The results were confirmed by the high respiratory activity of the hepatocytes in cell culture. Conclusion: We conclude that the silymarin-AuNP conjugate holds promise as a liver-protecting agent in acute liver disease caused by carbon tetrachloride poisoning.

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