scholarly journals Possibilities of using postnatal ultrasound screening of the uropoietic tract

2021 ◽  
Vol 4 (1) ◽  
pp. 39-42
Author(s):  
Kateryna Dmytriieva ◽  
Dmytro Dmytriiev
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Neonatal Period ◽  
Slovak Republic ◽  
Obstructive Uropathy ◽  
Main Task ◽  
Ultrasound Screening ◽  
Normal Functioning ◽  
Clinically Significant ◽  
Tract Infections

The article provides information on the possibilities of using postnatal ultrasound screening of the uropoietic tract illustrated by the results of using this method in the Slovak Republic. Its main task is to identify malformations of the uropoietic system that were not diagnosed during prenatal diagnosis. The most clinically significant malformations of the kidneys are associated with impaired urine flow (obstructive uropathy). Patients with these malformations often require surgical intervention in the neonatal period or in early childhood. Early diagnosis and timely correction of obstructive uropathy allows maintaining the normal functioning and morphological integrity of the kidneys, preventing the development of chronic kidney disease, improving the quality and life expectancy of patients. Thus, the costs of screening research are incommensurate with the consequences of an untimely diagnosed pathology and the treatment of complications such as chronic kidney disease, kidney failure, recurrent urinary tract infections (antibiotic therapy, hemodialysis, etc.).

P318 The nexus between chronic kidney disease and urinary tract infections

2017 ◽  
Author(s):  
Teofana Otilia Bizerea ◽  
Anca Roxana Paul ◽  
Ramona Stroescu ◽  
Raluca Isac ◽  
Mihai Gafencu ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Urinary Tract ◽  
Kidney Disease ◽  
Urinary Tract Infections ◽  
Tract Infections

scholarly journals Short- and long-term outcomes after incident pneumonia in adults with chronic kidney disease: a time-dependent analysis from the Stockholm CREAtinine Measurement project

2019 ◽  
Vol 35 (11) ◽  
pp. 1894-1900
Author(s):  
Guobin Su ◽  
Marco Trevisan ◽  
Junichi Ishigami ◽  
Kunihiro Matsushita ◽  
Cecilia Stålsby Lundborg ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Knee Joint ◽  
Joint Replacement ◽  
Cox Regression ◽  
Ckd Progression ◽  
Knee Joint Replacement ◽  
Adjusted Risk ◽  
Tract Infections ◽  
Pneumonia Diagnosis

Abstract Background Little is known about the health sequelae of pneumonia in persons with chronic kidney disease (CKD). Methods We studied adults with CKD in Stockholm during 2006–11, who not previously been diagnosed with lower respiratory tract infections. We used multivariable-adjusted Cox regression with pneumonia as a time-varying exposure to estimate hazard ratios (HRs) [95% confidence intervals (CIs)] for the events of death, major adverse cardiovascular events (MACEs), acute kidney injury (AKI), CKD progression or hospitalization for urinary tract infections (UTIs)/sepsis. Cataract and knee/joint replacement served as negative control outcomes. Results We identified 71 931 adults (mean age 79 years, 59% women), of whom 8379 (12%) were diagnosed with pneumonia during follow-up; incident pneumonia was associated with 10 times higher adjusted mortality risk during the first 90 days [HR = 10.0, 95% confidence interval (CI) 9.5–10.5] and double the mortality beyond 90 days from pneumonia diagnosis (HR = 2.0; 95% CI 1.9–2.1). Incident pneumonia was similarly associated with higher adjusted risk of MACE (<90 days: HR = 12.6; 95% CI 12.0–13.3; ≥90 days: HR = 1.5; 95% CI 1.4–1.6). The adjusted risk of CKD progression and UTI/sepsis hospitalization was highest within 90 days from pneumonia but remained elevated thereafter. For AKI, the association with incident pneumonia was only seen within 90 days. Neither cataract nor knee/joint replacement was related to pneumonia. Conclusions Incident pneumonia was associated with increased risks of MACE, CKD progression, severe UTI/sepsis and death, with risks highest soon after pneumonia diagnosis but extending beyond 90 days. Our findings highlight the susceptibility for adverse outcomes of CKD patients following pneumonia diagnosis, and may inform clinical decisions regarding vaccination strategies.

scholarly journals Purple Urine Bag Syndrome: More Than Eyes Can See

2019 ◽  
Vol 13 (3) ◽  
pp. 125-132 ◽  
Author(s):  
Nikos Sabanis ◽  
Eleni Paschou ◽  
Panagiota Papanikolaou ◽  
Georgios Zagkotsis
Keyword(s):  
Chronic Kidney Disease ◽  
Urinary Tract ◽  
Kidney Disease ◽  
Urinary Tract Infections ◽  
Predisposing Factors ◽  
Recruitment Strategy ◽  
Purple Urine Bag Syndrome ◽  
Tract Infections ◽  
Purple Urine

Background/Aims: Purple urine bag syndrome (PUBS) is an uncommon clinical entity characterized by purple urine discoloration in the setting of urinary tract infections. Pa-thophysiology of PUBS has been correlated to aberrant metabolism of tryptophan. Multiple predisposing factors have been recognized, namely: female gender, advanced age, constipation, institutionalization, long-term catheter-ization, dementia and chronic kidney disease. Herein, we present a comprehensive review of all PUBS cases reported in PubMed, focusing on the predisposing factors and the microorganisms related to PUBS. Methods: We performed a search in PubMed database for articles referring to PUBS, published in English, French, Spanish and German from January 1978 until November 2017. The literature recruitment strategy was based on several keywords and Medical Subject Heading combination such as “purple urine bag syndrome” or PUBS or “urine discoloration”. The finally selected articles were categorized into case reports/series (88 articles including 112 patients) and studies (10 articles including 134 patients). Demographical data as well as predisposing factors were recorded and further analyzed. Results: According to our findings, mean age of PUBS patients was 78.9 ± 12.3 years, 70.7% were female while 90.1% were suffering from constipation, 76.1% were in a bedridden situation, 45.1% were experiencing long-term catheterization, 42.8% had been diagnosed with dementia, 14.3% had recurrent urinary tract infections and 14.1% were chronic kidney disease patients. 91.3% of patients presenting with PUBS alkaline urine were observed while the most common microbe in urine cultures was E. coli. Conclusions: PUBS is considered benign process in the majority of catheterized patients. Clinicians should be aware of the syndrome that may indicate serious comorbidities.

scholarly journals Pharmacotherapy assessment in chronic kidney disease: validation of the pair instrument for use in Brazil

2020 ◽  
Author(s):  
Alessandra Batista Marquito ◽  
Hélady Sanders Pinheiro ◽  
Natália Maria da Silva Fernandes ◽  
Rogério Baumgratz de Paula
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Clinical Judgment ◽  
Medical Records ◽  
Chronic Renal Disease ◽  
Drug Related Problems ◽  
Longitudinal Observational Study ◽  
Clinically Significant ◽  
Validated Instrument ◽  
Level Of Agreement

Abstract Individuals with chronic kidney disease (CKD) use polypharmacy, which, in combination with renal impairment, exposes them to the risk of drug-related problems (DRPs). There are no available tools in Brazil to systematically assess the pharmacotherapy and management of DRPs in this population. Therefore, the objective of this work was to validate the PAIR instrument (Pharmacotherapy Assessment in Chronic Renal Disease) for use in Brazilian Portuguese. This is a retrospective longitudinal observational study. Medical records from 100 CKD patients under conservative treatment, between 2016 and 2017, in a nephrology clinic, were analyzed. PAIR was applied by pharmacists in two consultations of the same patient, with an interval of 6 months. Reliability, conceptual validity, responsiveness of the instrument and prevalence of DRPs in the studied sample were assessed. A mean of 1.26 ± 0.96 DRPs/patient was identified. Inter-rater reliability coefficients (k) ranged from 0.58 to 0.94 and from 0.79 to 1.00 for test-retest, revealing moderate to perfect level of agreement. In conceptual validity, a mean of 1.60 ± 1.24 DRPs/patient was identified by the nephrologist through clinical judgment, compared to 1.33±0.76 DRPs/patient identified by the pharmacist using PAIR (p = 0.07). Therefore PAIR allowed the identification of clinically significant DRPs. In responsiveness, a mean of 1.26 ± 0.96 DRPs/patient was identified at the first consultation and 1.11 ± 1.02 DRPs/patient at the subsequent consultation (p = 0.17) by the pharmacist using PAIR. The number of DRPs between the periods did not change. As a conclusion, the PAIR allowed the identification of clinically significant DRPs in CKD, constituting a new validated instrument to be used in Brazil.

scholarly journals Pediatric chronic kidney disease rates in Southern Israel are higher than reported

F1000Research ◽  
2013 ◽  
Vol 2 ◽  
pp. 186
Author(s):  
Daniel Landau ◽  
Ruth Schreiber ◽  
Anya Kleinman ◽  
Alina Vodonos ◽  
Hannah Shalev
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Obstructive Uropathy ◽  
Pediatric Nephrology ◽  
Developed Countries ◽  
Renal Diseases ◽  
Disease Rates ◽  
Ckd Stage ◽  
Stage 1 ◽  
Diagnosis Age

Background: The incidence and prevalence of pediatric chronic kidney disease (p-CKD) in developed countries has previously been estimated to be 12 and 75 cases/106 population respectively, much lower than reports in young adults (age 20-40) (40,000/106). Thus, the extent of p-CKD may be underestimated.Methods: Being the only Pediatric Nephrology center in Southern Israel, we reviewed all detected cases of p-CKD (stages 1-5) between 1994-2008. We then prospectively summarized the incidence and prevalence of CKD between 2009-2010. Results: We retrospectively identified 192 children (53.9% of Bedouin origin, 53.4% males, median diagnosis age: 1 year) with CKD. The prevalence in December 2008 was 795 cases/106 for all CKD stages and 331/106 for CKD stage >2. Calculated incidence for the study period (1994-2008) was 46/106/year. The main CKD etiologies were: hypodysplasia: 35%; obstructive uropathy: 13%; genetic renal diseases: 28% and glomerulonephritis: 15%. The proportions of children in each CKD stage were as follows: stage 1: 50%; stages 2-4: 30%; stage 5: 20%. During a subsequent two-year study period we identified 26 new CKD cases (incidence: 54 cases/106/year). Conclusions: p-CKD rates in our area are higher than reported and maybe even higher if asymptomatic populations are screened. Fifty percent of detected cases have CKD stage 1. This may contribute significantly to CKD beyond the pediatric age.

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