Economic comparison of common treatment protocols and J5 vaccination for clinical mastitis in dairy herds using optimized culling decisions

Clinical mastitis (CM) is the most common microbial disease treated in dairy cows. We analyzed the antimicrobial usage in cows with CM (n = 11,420) in large dairy herds (n = 43) in Estonia. CM treatment data were collected during a 12-month study period. The antimicrobial usage was observed during the 21 days from the initiation of treatment, and the incidence of antimicrobial-treated CM was calculated for each study herd. The effect of intramammary (IMM), systemic, and combined (systemic and IMM) penicillin treatment of CM on the post-treatment somatic cell count (SCC) was analyzed using the treatment records of 2222 cows from 24 herds with a mixed multivariable linear regression model. The median incidence of antimicrobial-treated CM was 35.8 per 100 cow-years. Procaine benzylpenicillin and marbofloxacin were used in 6103 (35.5%, 95% CI 34.8–36.2) and 2839 (16.5%, 95% CI 16.0–17.1) CM treatments, respectively. Post-treatment SCC was higher after IMM penicillin therapy compared to systemic or combination therapy. Treatment of CM usually included first-choice antimicrobials, but different antimicrobial combinations were also widely used. The effect of procaine benzylpenicillin to post-treatment SCC was dependent on the administration route, cow parity, and days in milk. Further studies should evaluate the factors affecting veterinarians’ choice of antimicrobial used in the treatment of CM.

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Comparison of Ketosis, Clinical Mastitis, Somatic Cell Count, and Reproductive Performance between Free Stall and Tie Stall Barns in Norwegian Dairy Herds with Automatic Feeding

Acta Veterinaria Scandinavica ◽

10.1186/bf03548498 ◽

1997 ◽

Vol 38 (2) ◽

pp. 181-192

Author(s):

J. P. Valde ◽

D. W. Hird ◽

M. C. Thurmond ◽

O. Østerås

Keyword(s):

Somatic Cell ◽

Cell Count ◽

Reproductive Performance ◽

Somatic Cell Count ◽

Clinical Mastitis ◽

Dairy Herds ◽

Norwegian Dairy

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Characterization of Escherichia coli Strains Derived from Cow Milk of Subclinical and Clinical Cases of Mastitis

Applied Sciences ◽

10.3390/app11020541 ◽

2021 ◽

Vol 11 (2) ◽

pp. 541

Author(s):

Katarzyna Grudlewska-Buda ◽

Krzysztof Skowron ◽

Ewa Wałecka-Zacharska ◽

Natalia Wiktorczyk-Kapischke ◽

Jarosław Bystroń ◽

...

Keyword(s):

Escherichia Coli ◽

Bacterial Species ◽

Subclinical Mastitis ◽

Clinical Mastitis ◽

Economic Problem ◽

Cow Milk ◽

P Value ◽

Dairy Herds ◽

E Coli ◽

Bonferroni Test

Mastitis is a major economic problem in dairy herds, as it might decrease fertility, and negatively affect milk quality and milk yield. Out of over 150 bacterial species responsible for the udder inflammation, Escherichia coli is one of the most notable. This study aimed to assess antimicrobial susceptibility, resistance to dipping agents and biofilm formation of 150 E. coli strains isolated from milk of cows with subclinical and clinical mastitis. The strains came from three dairy herds located in Northern and Central Poland. The statistical analyses were performed with post-hoc Bonferroni test and chi-square test (including Yates correction). The data with a p value of <0.05 were considered significant. We found that the tested strains were mostly sensitive to antimicrobials and dipping agents. It was shown that 37.33% and 4.67% of strains were resistant and moderately resistant to at least one antimicrobial agent, respectively. No extended-spectrum beta-lactamases (ESBL)-producing E. coli were detected. The majority of strains did not possess the ability to form biofilm or formed a weak biofilm. The strong biofilm formers were found only among strains derived from cows with subclinical mastitis. The lowest bacteria number was noted for subclinical mastitis cows’ strains, after stabilization with iodine (3.77 log CFU × cm−2) and chlorhexidine (3.96 log CFU × cm−2) treatment. In the present study, no statistically significant differences in susceptibility to antibiotics and the ability to form biofilm were found among the strains isolated from cows with subclinical and clinical mastitis. Despite this, infections in dairy herds should be monitored. Limiting the spread of bacteria and characterizing the most common etiological factors would allow proper treatment.

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