Differences in surgical outcomes for patients with craniosynostosis in the US: impact of socioeconomic variables and race

2016 ◽  
Vol 17 (1) ◽  
pp. 27-33 ◽  
Author(s):  
Faris Shweikeh ◽  
David Foulad ◽  
Miriam Nuño ◽  
Doniel Drazin ◽  
Matthew A. Adamo
Keyword(s):  
Private Insurance ◽  
International Classification Of Diseases ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Hospital Charges ◽  
Teaching Hospitals ◽  
National Study ◽  
Current Recommendation ◽  
National Trends ◽  
Neurosurgical Intervention

OBJECT Craniosynostosis is often treated with neurosurgical intervention. The aim of this study was to report and analyze the clinical and socioeconomic characteristics of patients with craniosynostosis and to present current national trends. METHODS Using the Kids’ Inpatient Database for the years 2000, 2003, 2006, and 2009, the authors identified patients with craniosynostosis using International Classification of Diseases, Ninth Revision, Clinical Modification diagnosis codes and their associated procedure codes. Clinical features, demographics, inpatient procedures, outcomes, and charges were collected and analyzed. RESULTS Of the 3415 patients identified, 65.8% were White, 21.4% were Hispanic, and 3.2% were Black. More than 96% were treated at urban teaching hospitals and 54.2% in southern or western regions. White patients were younger (mean 6.1 months) as compared with Blacks (mean 10.9 months) and Hispanics (mean 9.1 months; p < 0.0001) at the time of surgery. A higher fraction of Whites had private insurance (70.3%) compared with nonwhites (34.0%–41.6%; p < 0.001). Approximately 12.2% were nonelective admissions, more so among Blacks (16.9%). Mean hospital length of stay (LOS) was 3.5 days with no significant differences among races. Following surgical treatment, 12.1% of patients developed complications, most commonly pulmonary/respiratory (4.8%), wound infection (4.4%), and hydrocephalus (1.4%). The mean overall hospital charges were significantly lower for Whites than nonwhites ($34,527 vs $44,890–$48,543, respectively; p < 0.0001). CONCLUSIONS The findings of this national study suggest a higher prevalence of craniosynostosis in Hispanics. The higher predisposition among males was less evident in Hispanics and Blacks. There was a significant percentage of nonelective admissions, more commonly among Blacks. Additionally, Hispanics and Blacks were more likely to receive surgery at an older age, past the current recommendation of the optimum age for surgical intervention. These findings are likely associated with a lack of early detection. Although mean LOS and rate of complications did not significantly differ among different races, nonwhites had, on average, higher hospital charges of $10,000–$14,000. This discrepancy may be due to differences in type of insurance, craniosynostosis type, rates of comorbidities, and delay in treatment. Although there are several limitations to this analysis, the study reports on relevant disparities regarding a costly neurosurgical intervention, and ways to diminish these disparities should be further explored.

Influence of acute graft-versus-host disease (aGVHD) during allogeneic hematopoietic stem cell transplantation (HSCT) engraftment admission on hospital length of stay (LOS), charges, and costs.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e18544-e18544
Author(s):  
Jingbo Yu ◽  
Shreekant Parasuraman ◽  
Anshul Shah ◽  
Siva Narayanan
Keyword(s):  
Resource Use ◽  
Private Insurance ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Hospital Charges ◽  
Cost Ratio ◽  
Hematopoietic Stem ◽  
Allogeneic Hsct ◽  
Wilcoxon Rank Sum Test ◽  
Stratified Sample

e18544 Background: aGVHD is a common complication of allogeneic HSCT and a significant cause of transplant-related morbidity and mortality. Limited data exist on healthcare resource use and costs of aGVHD during HSCT engraftment admission. This study estimated LOS, charges, and costs of aGVHD during HSCT engraftment admission in the US. Methods: Inpatient discharges between 2009-2013 using the Nationwide In-patient Sample (NIS) database were analyzed. NIS is a representative (20% stratified) sample of all discharges from US community hospitals included in the Healthcare Cost and Utilization Project (HCUP). Discharges for allogeneic HSCT engraftment admissions with aGVHD (ICD-9 279.51) were compared with those without GVHD. Costs were calculated from hospital charges using a standard HCUP Charge-to-Cost Ratio. LOS, charges, and costs were compared using Wilcoxon rank sum test. Correlation between LOS and charges or costs was calculated using Pearson’s coefficient. Results: 729 discharges with aGVHD and 5958 discharges without GVHD were analyzed. Demographic characteristics were similar for both groups except age: female (40% vs 42%), Caucasian (67% vs 68%), private insurance (60% vs 63%); mean age was 39 and 45 years for patients with and without aGVHD respectively (p < 0.001). In-hospital mortality rate was 16% for patients with aGVHD vs 5% without GVHD (p < 0.001). Despite younger age of the aGVHD group, mean unadjusted LOS was significantly longer, and mean unadjusted charges and costs were significantly higher with aGVHD vs without GVHD (54.2 days vs 29.8 days, $690,244 vs $366,213, $218,425 vs $122,387, respectively). Charges and costs were directly proportional to LOS (r = 0.711, p < 0.001). Conclusions: Overall, occurrence of aGVHD during HSCT engraftment admission resulted in almost doubling of LOS, charges, and costs. Mitigating aGVHD may reduce LOS and subsequent inpatient resource use for HSCT. [Table: see text]

Abstract WP355: Intracerebral Hemorrhage Care in a Stroke Unit is Safe and Associated With Lower Costs

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Corey R Fehnel ◽  
Linda C Wendell ◽  
N. Stevenson Potter ◽  
Kimberly Glerum ◽  
Richard N Jones ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Stroke Unit ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Hospital Charges ◽  
Total Hospital ◽  
Reduced Costs ◽  
Reducing Costs ◽  
Ich Score ◽  
Median Hospital

Background: There is little data to support level of care decisions for lower risk intracerebral hemorrhage (ICH) patients. The addition of a dedicated stroke unit (SU) at our institution allowed for a comparison of such patients cared for in the intensive care unit (ICU) or SU. We hypothesized that SU care of select ICH patients would not change functional outcome, and result in reduced costs. Methods: Two retrospective cohorts of consecutive patients with small (<20 cc) supratentorial ICH and the absence of anticoagulation were enrolled. In the first study period from August 1, 2008 to February 1, 2011, patients were admitted to the neurological or medical ICU (historical control). In the second study period from August 1, 2012 to January 30, 2014, patients were admitted to a dedicated SU. Intubated patients, those requiring vasopressors, osmotic therapy, or ventriculostomy were excluded. Primary outcomes were discharge modified Rankin Score (mRS) and total hospital charges. Multivariate analyses were used for predicting mRS and early complications. Results: There were 104 patients included in the analysis (41 ICU, 63 SU). Mean age, gender and race did not differ significantly between groups. Mean ICH volume was 6cc in the SU group and 8cc in the ICU group (P>.05). Prior antiplatelet use, ICH location, and ICH score did not differ between groups. Intraventricular hemorrhage and hydrocephalus were more common in the ICU group (P<.001). Two SU patients transferred to the ICU for pneumonia and acute myocardial infarction. There were no significant differences in complications such as ICH expansion, use of osmotic therapy, seizures, or pneumonia. There was no difference in discharge mRS between groups (P>.05). Median hospital length of stay was 6 days in the ICU group and 3 days in SU group (P<.001). Median direct costs for the ICU group were $5,859 (IQR 4,782-9,733) and were $4,078 (IQR 2,861-6,865) for the SU group (P<.001). Unit of admission was not a significant predictor of early complication (P=.73) or discharge mRS (P=.43) in multivariate analysis. Conclusions: This preliminary retrospective study provides support for select low-risk ICH patients to be safely cared for in a lower intensity setting with potential for reducing costs.

Abstract 16190: National Trends in RSV Hospitalizations in Children With Hemodynamically Significant Heart Disease, 1997-2009

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Patricia Y Chu ◽  
Christoph P Hornik ◽  
Jennifer S Li ◽  
Michael J Campbell ◽  
Kevin D Hill
Keyword(s):  
Heart Disease ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Early Adoption ◽  
Rsv Infection ◽  
Common Ventricle ◽  
Syncytial Virus ◽  
National Trends ◽  
Left Heart Syndrome ◽  
The Impact

Background: Children with hemodynamically significant heart disease (HS-HD) are at risk for morbidities and mortality due to respiratory syncytial virus (RSV). Palivizumab was approved for RSV prophylaxis in 1998. Guidelines released in December 2003 recommend palivizumab for all children < 2 yrs with HS-HD. We sought to define the impact of RSV prophylaxis in children with HS-HD by evaluating trends in U.S. RSV hospitalizations. Methods: The 1997, ’00, ’03, ’06 and ’09 Healthcare Cost and Utilization Project (HCUP) Kids’ Inpatient Databases (KID) were used to estimate U.S. RSV hospitalizations in children < 2 yrs, overall and in those with HS-HD, using standard HCUP weighting methods. RSV was defined by ICD-9-CM codes for RSV infection. HS-HD was defined using ICD-9-CM codes from the Clinical Classifications Software for congestive heart failure, or an ICD-9-CM code for pulmonary hypertension, common truncus, common ventricle, or hypoplastic left heart syndrome. Results: Our cohort included an estimated 461,491 RSV hospitalizations; 2,132 in children with HS-HD. Figure 1 depicts hospitalizations over time. There was no evident trend in number of overall RSV hospitalizations, however RSV hospitalizations in children with HS-HD declined by 39% from ’97 to ‘09. The largest decline was from ’97-’03. RSV hospitalizations in children with HS-HD relative to overall hospitalizations in children with HS-HD declined annually from ’97-’06 with a small increase in ‘09 (3.8%, 3.5%, 3.0%, 2.3% and 2.6% for successive analytic years). In 2009 mean hospital length of stay for children with HS-HD and RSV was 22.5 ± 2.1 days. Conclusions: RSV disease burden in children with HS-HD has declined since palivizumab approval. Much of this decline occurred before palivizumab was recommended for use in HS-HD, perhaps reflecting early adoption of prophylaxis, or greater awareness of alternative preventative strategies. RSV remains a significant cause of morbidity in children with HS-HD.

scholarly journals Outcomes and National Trends for the Surgical Treatment of Lumbar Spine Trauma

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Doniel Drazin ◽  
Miriam Nuno ◽  
Faris Shweikeh ◽  
Alexander R. Vaccaro ◽  
Eli Baron ◽  
...  
Keyword(s):  
Patient Safety ◽  
Lumbar Spine ◽  
Univariate Analysis ◽  
Multivariable Analysis ◽  
Compression Fracture ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Nationwide Inpatient Sample Database ◽  
Average Patient ◽  
National Trends

Introduction. Operative treatment of lumbar spine compression fractures includes fusion and/or cement augmentation. Our aim was to evaluate postoperative differences in patients treated surgically with fusion, vertebroplasty, or kyphoplasty.Methods. The Nationwide Inpatient Sample Database search for adult vertebral compression fracture patients treated 2004–2011 identified 102,316 surgical patients: 30.6% underwent spinal fusion, 17.1% underwent kyphoplasty, and 49.9% underwent vertebroplasty. Univariate analysis of patient and hospital characteristics, by treatment, was performed. Multivariable analysis was used to determine factors associated with mortality, nonroutine discharge, complications, and patient safety.Results. Average patient age: fusion (46.2), kyphoplasty (78.5), vertebroplasty (76.7) (p<.0001). Gender, race, household income, hospital-specific characteristics, and insurance differences were found (p≤.001). Leading comorbidities were hypertension, osteoporosis, and diabetes. Risks for higher mortality (OR 2.0: CI: 1.6–2.5), nonroutine discharge (OR 1.6, CI: 1.6–1.7), complications (OR 1.1, CI: 1.0–1.1), and safety related events (OR 1.1, CI: 1.0–1.1) rose consistently with increasing age, particularly among fusion patients. Preexisting comorbidities and longer in-hospital length of stay were associated with increased odds of nonroutine discharge, complications, and patient safety.Conclusions. Fusion patients had higher rates of poorer outcomes compared to vertebroplasty and kyphoplasty cohorts. Mortality, nonroutine discharge, complications, and adverse events increased consistently with older age.

scholarly journals Surgical treatment of adolescent idiopathic scoliosis in the United States from 1997 to 2012: an analysis of 20, 346 patients

2015 ◽  
Vol 16 (3) ◽  
pp. 322-328 ◽  
Author(s):  
Hari T. Vigneswaran ◽  
Zachary J. Grabel ◽  
Craig P. Eberson ◽  
Mark A. Palumbo ◽  
Alan H. Daniels
Keyword(s):  
Surgical Treatment ◽  
Adolescent Idiopathic Scoliosis ◽  
Idiopathic Scoliosis ◽  
The United States ◽  
Hospital Length ◽  
Operative Approach ◽  
Hospital Length Of Stay ◽  
Hospital Charges ◽  
Average Hospital ◽  
The Mean

OBJECT Adolescent idiopathic scoliosis (AIS) can cause substantial morbidity and may require surgical intervention. In this study, the authors aimed to evaluate US trends in operative AIS as well as patient comorbidities, operative approach, in-hospital complications, hospital length of stay (LOS), and hospital charges in the US for the period from 1997 to 2012. METHODS Patients with AIS (ICD-9-CM diagnosis codes 737.30) who had undergone spinal fusion (ICD-9-CM procedure codes 81.xx) from 1997 to 2012 were identified from the Kids' Inpatient Database. Parameters of interest included patient comorbidities, operative approach (posterior, anterior, or combined anteroposterior), in-hospital complications, hospital LOS, and hospital charges. RESULTS The authors identified 20, 346 patients in the age range of 0–21 years who had been admitted for AIS surgery in the defined study period. Posterior fusions composed 63.4% of procedures in 1997 and 94.1% in 2012 (r = 0.95, p < 0.01). The mean number of comorbidities among all fusion groups increased from 3.0 in 1997 to 4.2 in 2012 (r = 0.92, p = 0.01). The percentage of patients with complications increased from 15.6% in 1997 to 22.3% in 2012 (r = 0.78, p = 0.07). The average hospital LOS decreased from 6.5 days in 1997 to 5.6 days in 2012 (r = -0.86, p = 0.03). From 1997 to 2012, the mean hospital charges (adjusted to 2012 US dollars) for surgical treatment of AIS more than tripled from $55,495 in 1997 to $177,176 in 2012 (r = 0.99, p < 0.01). CONCLUSIONS Over the 15-year period considered in this study, there was an increasing trend toward using posterior-based techniques for AIS corrective surgery. The number of comorbid conditions per patient and thus the medical complexity of patients treated for AIS have increased. The mean charges for the treatment of AIS have increased, with a national bill over $1.1 billion per year in 2012.

scholarly journals National trends in hospital length of stay for acute myocardial infarction in China

2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Qian Li ◽  
Zhenqiu Lin ◽  
Frederick A Masoudi ◽  
Jing Li ◽  
Xi Li ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Length Of Stay ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
National Trends

Incidence, Cost, and Mortality Associated With Hospital-Acquired Conditions After Resection of Cranial Neoplasms

Neurosurgery ◽  
2014 ◽  
Vol 74 (6) ◽  
pp. 638-647 ◽  
Author(s):  
Brad E. Zacharia ◽  
Christopher Deibert ◽  
Gaurav Gupta ◽  
Dawn Hershman ◽  
Alfred I. Neugut ◽  
...  
Keyword(s):  
Hospital Costs ◽  
Hospital Length Of Stay ◽  
Hospital Charges ◽  
Teaching Hospitals ◽  
Surgical Volume ◽  
Hospital Level ◽  
Odds Ratios ◽  
Medical Comorbidities ◽  
Hospital Acquired Conditions ◽  
Hospital Acquired

ABSTRACT BACKGROUND: In 2007, the Centers for Medicare and Medicaid Services stopped reimbursing for treatment of specified hospital-acquired conditions (HACs), also known as “never events.” OBJECTIVE: To establish benchmarks for HACs after common neurosurgical oncologic procedures. METHODS: We identified adults in the Nationwide Inpatient Sample between 2002 and 2009 who underwent resection of a benign or malignant brain tumor. Baseline demographics, medical comorbidities, and hospital-level variables were assessed. A generalized estimating equation, multivariable-logistic model was used to identify predictors of HACs, mortality, prolonged hospital length of stay, and increased hospital charges. RESULTS: We identified 310,133 patients undergoing surgical treatment of a cranial neoplasm; 5.4% experienced an HAC. More medical comorbidities and the presence of an immediate postoperative neurosurgical complication increased one's risk of having an HAC (odds ratios: 1.56 and 2.48, respectively; both P &lt; .01). Patients who experienced an HAC faced increased in-hospital mortality (6.47% vs 1.53%; P &lt; .01) and increased total hospital costs ($52,882.61 vs $25,569.45; P &lt; .01). Patients at urban teaching hospitals and those with a high surgical volume were more likely to experience an HAC compared with those treated at rural nonteaching hospitals and those with a low surgical volume (odds ratios: 1.33 and 1.16, respectively; P &lt; .01). CONCLUSION: We found a 5.4% incidence of HACs after neurosurgical oncologic procedures, which varied based on several patient and hospital-level factors. A thorough analysis of the relationship between patient, procedure, and HAC incidence will be important to developing fair compensation practices for physicians as well as payers. Additionally, further investigation may identify opportunities for future quality improvement initiatives.

scholarly journals Medication omissions in the first 48 hours after admission: failure in prescribed medicines reaching in-patients in paediatrics wards at the University Teaching Hospitals, Children’s Hospital in Lusaka, Zambia

2021 ◽  
Vol 10 (12) ◽  
pp. 1324
Author(s):  
Martin Kampamba ◽  
Steven Mulolo ◽  
Margaret Phiri ◽  
Martha Chibale Chulu ◽  
Webrod Mufwambi ◽  
...  
Keyword(s):  
Medication Administration ◽  
Median Number ◽  
Hospital Length ◽  
University Teaching ◽  
Hospital Length Of Stay ◽  
Teaching Hospitals ◽  
Prescribed Medicines ◽  
The University ◽  
University Teaching Hospitals ◽  
Omission Errors

Background: The first few days of in-patient care are possibly the most significant in a patient’s recovery and any omitted medications during this period may harm the patient or increase their hospital length of stay. Therefore, our study aimed at assessing the frequency of medication administration omission errors and their reasons for the omission in the paediatric wards after admission at University Teaching Children’s Hospital.Methods: This was a descriptive study in which 259 patient files and drug charts were reviewed. Admission prescription charts were studied in detail over a period of four weeks and all drugs prescribed but then not given in the first 48 hours were recorded as omitted medications, along with the reason given for their omission.Results: From the 259 drug charts, a total of 1598 doses of drugs were ordered within 48 hours of admission. However, from this, only a total of 1132 doses were administered with the remaining 466 doses omitted, which accounted for a frequency of 29.2%. When the frequency of medication omission errors was compared, parenteral drugs (70.8% vs. 25.3%, [p=0.0001]), afternoon shift (48.5% vs. 15.8%, [p=0.0001]), and anti-infective medications (69.1% vs. 39.4%, [p=0.0001]) were found to be the most frequently omitted medications. There were also considerably more medication omissions in patients prescribed with more medications (median number: 4, I QR [2, 6] vs. median number: 2, IQR [2, 4], [p=0. 0.001]). The most common reason for the omission was medication unavailability (89.3%), followed by work overload (71.4%), and the patient is off the ward (71.4%).Conclusions: This study revealed that medication omissions are a continuing problem and this may result in increased morbidity and mortality rates. There is a need to put in place specific strategies to reduce this problem. 

Enterocutaneous Fistula Complicating Trauma Laparotomy: A Major Resource Burden

2009 ◽  
Vol 75 (1) ◽  
pp. 30-32 ◽  
Author(s):  
Pedro G.R. Teixeira ◽  
Kenji Inaba ◽  
Joseph Dubose ◽  
Ali Salim ◽  
Carlos Brown ◽  
...  
Keyword(s):  
Length Of Stay ◽  
Injury Severity Score ◽  
Resource Utilization ◽  
Severity Score ◽  
Injury Severity ◽  
Enterocutaneous Fistula ◽  
Hospital Length ◽  
Hospital Length Of Stay ◽  
Hospital Charges ◽  
Hollow Viscus

Enterocutaneous fistula (ECF) is an uncommon and poorly studied postoperative complication. The objective of this study was to analyze the incidence and resource utilization of patients who developed an ECF after trauma laparotomy. All patients with an ECF occurring after trauma laparotomy at a Level I trauma center were identified through a review of both the Trauma Registry and the Morbidity and Mortality reports for a 9-year period ending in December 2006. Each ECF case was matched with a control (non-ECF) that did not develop this complication after laparotomy. The matching criteria were: age, gender, mechanism of injury, Injury Severity Score, Abbreviated Injury Score, and damage control laparotomy requiring an open abdomen. Outcomes analyzed were intensive care unit (ICU) and hospital length of stay, mortality, and total hospital charges. During the 9-year period, of 2373 acute trauma laparotomies performed, 36 (1.5%) patients developed an enterocutaneous fistula, and were matched to 36 controls. Patients with an ECF were 31 ± 12 years of age, were 97 per cent male, had a mean Injury Severity Score of 21 ± 10, and 75 per cent were penetrating. Eighty-nine per cent of the ECF patients had a hollow viscus injury. The most common was colon (69%), followed by small bowel (53%), duodenum (36%), and stomach (19%). Fifty-six per cent of the ECF patients had multiple hollow viscus injuries. The development of an ECF was associated with significantly increased ICU length of stay (28.5 ± 30.5 vs 7.6 ± 9.3 days, P = 0.004), hospital length of stay (82.1 ± 100.8 vs 16.2 ± 17.3 days, P < 0.001), and hospital charges ($539,309 vs $126,996, P < 0.001). In conclusion, the development of an enterocutaneous fistula after laparotomy for trauma resulted in a significant impact on resource utilization including longer ICU and hospital length of stay and higher hospital charges. Further investigation into the prevention and treatment of this costly complication is warranted.

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