Seizures associated with the use of meglumine iothalamate 60% in ventriculography

1972 ◽  
Vol 36 (4) ◽  
pp. 474-480 ◽  
Author(s):  
Jorge A. Picaza ◽  
Sam E. Hunter ◽  
Ling Lee

✓ Meglumine iothalamate 60% (Conray) is a water-soluble substance being developed for the roentgenographic visualization of the cerebral ventricular system. Although it offer definite advantages compared to other contrast media, a recognized disadvantage is the possible development of seizures. This complication seems to be relatively rare and largely preventable, but once present may seriously endanger the patient's life. It appears to be a neurotoxic phenomenon, resistant to the usual anticonvulsant medications, and requires the availability of sophisticated personnel and emergency procedures to prevent death.

1971 ◽  
Vol 34 (3) ◽  
pp. 408-411 ◽  
Author(s):  
Sanford R. Weiss ◽  
Robert Raskind

✓ In view of the technical complexity of gas ventriculography and the physiologic hazards of water insoluble contrast media, methylglucamine iothalamate 60% (Conray) was used in the diagnosis of brain tumor or congenital malformation in 15 children 1 mos to 10 yrs of age. The method proved simple, reliable, and radiographically satisfactory. General or local anesthesia was used. It was not necessary to change the position of the head during study. The medium left the ventricular system within 5 to 10 min and was excreted in the urine within 24 hrs. No complications occurred.


1973 ◽  
Vol 39 (3) ◽  
pp. 359-361 ◽  
Author(s):  
Isaac Z. Kosary ◽  
Rina Tadmor ◽  
George Ouaknine ◽  
Jackson Braham

✓ The authors report the use of the water-soluble spinal contrast medium Dimer-X in 100 cases of suspected lumbar disc disease. It was particularly valuable in delineating small laterally-placed protrusions causing root compression, which are often difficult to demonstrate with oily contrast media. Side effects were mild and transient, and no serious complications were encountered.


2013 ◽  
Vol 675 ◽  
pp. 317-321
Author(s):  
Meng Ying Fang ◽  
Li Chun Liu ◽  
Fang Yin ◽  
Wu Di Zhang ◽  
Shi Qing Liu ◽  
...  

Using petroleum ether to extract the fermentative fluid (bio-slurry), then to get the inhibition mechanism of it, and infer which is the main component in inhibition mechanism of biogas. The conclusion found by the experiment is that fat soluble substance is better than water soluble substance in inhibition mechanism, and fat soluble substance is close to 75% biogas fermentation fluid, while water soluble substance is worst. That is to say, the main subject in inhibition mechanism is hided in the fat soluble substance.


2020 ◽  
Vol 60 (10) ◽  
pp. 2496-2510
Author(s):  
Maja D. Markovic ◽  
Vesna V. Panic ◽  
Sanja I. Seslija ◽  
Pavle M. Spasojevic ◽  
Vukasin Dj. Ugrinovic ◽  
...  

1974 ◽  
Vol 41 (1) ◽  
pp. 20-28 ◽  
Author(s):  
Howard M. Eisenberg ◽  
James E. McLennan ◽  
Keasley Welch

✓ Cats were made hydrocephalic by cisternal instillation of kaolin. Three to 8 weeks later it was found by perfusion between the ventricular system and the spinal subarachnoid space that communication had been reestablished through a demonstrably dilated central canal of the spinal cord. Absorption of fluid from the ventricular system, measured both by ventriculospinal perfusion and, after ligation of the spinal cord, by perfusion between the lateral ventricles, was found to be indistinguishable from zero over a wide range of ventricular pressure.


1973 ◽  
Vol 38 (2) ◽  
pp. 204-214 ◽  
Author(s):  
Francisco Velasco ◽  
Pedro Molina-Negro

✓ Microelectrode recordings made in 64 human cases of movement disorder or intractable pain were used to study the relation of the site of electrical activity to the ventricular system. Standardizing the cases by dividing the AC-PC line in equal parts and using the same units to divide the areas above and below the intercommissural line and the distance of the electrodes to the midline revealed that the dispersion of the electrical activities in regard to AC-PC line was minimal and overlapping practically nonexistent. It is concluded that, at least for the areas explored, the size of each diencephalon nucleus is proportional to the size of other diencephalic nuclei, and its internal structure and relation to radiological landmarks are fairly constant.


1972 ◽  
Vol 36 (3) ◽  
pp. 348-350 ◽  
Author(s):  
Albert L. Rhoton ◽  
Manuel R. Gomez

✓ A patient with postinflammatory hydrocephalus had a multiloculated, lateral ventricular system that was treated by a routine shunting procedure after the multiloculated system had been converted into a uniloculated system by direct intraventricular surgery.


1983 ◽  
Vol 58 (4) ◽  
pp. 531-537 ◽  
Author(s):  
Burton P. Drayer ◽  
Charles Vassallo ◽  
Abraham Sudilovsky ◽  
J. Scott Luther ◽  
Robert H. Wilkins ◽  
...  

✓ A double-blind study was performed to compare metrizamide with the new iodinated water-soluble nonionic contrast medium, iopamidol, for conventional and computerized tomography lumbosacral myelography. Both contrast agents were used in 30 patients, and were equivalent in terms of image quality and clinical accuracy. Headaches and nausea were less severe using iopamidol. The most striking difference was found in adverse neurobehavioral reactions and associated electroencephalographic abnormalities, which were noted in 17% of the metrizamide group but were not seen with the use of iopamidol. Iopamidol appears to be superior to metrizamide for intrathecal applications. An explanation of the differential neurotoxicity is provided.


2015 ◽  
Vol 1 (2) ◽  
pp. 102
Author(s):  
Anwar Kasim ◽  
Yoli Sub’han ◽  
Netty Sri Indeswari

ABSTRACT Studying about the change of physical and chemical properties Gambir paste during 28 days was conducted in order to know the change primarily the chemical content and physical properties as storage consequences. Experimental design was used completely randomized design for 4, 8, 12, 16, 20, 24, and 28 days storage periods. Replication was two and as a control was used paste non treatment. F-test and T-Dunnet test were applicated for statistical analysis. The result indicated that treatment can not change physical properties but change the chemical properties gambir paste. The initial water contents of gambir paste was 72.26% and after 28 days storage 71.68%. Color of gambir paste was still yellow during storage. The initial non water soluble substance was 6.96% and after 28 days storage 4.69%. The initial non alcohol soluble substance was 14.83% and after 28 days storage 13.15%. The initial chatechin contents was 72.22% and after 28 days storage 65.38%. The initial tannin contents 38.68% and after 28 days storage 35.12%. Total ash content of gambir paste was 2.72%.   Keywords : gambir, paste, storage, change, properties


1935 ◽  
Vol 13b (5) ◽  
pp. 269-275 ◽  
Author(s):  
G. H. Findlay ◽  
J. F. Snell

Skazin's observation that maple flavor is not present as such in sugar maple sap but develops at boiling temperatures (100–104 °C.) has been confirmed. Levorotatory glucosides cannot be detected in sap concentrated to 1/150 its volume, and are therefore probably not present in amounts exceeding 1 gm. (calculated as coniferin) per 50 litres. In maple wood, pyrocatechol tannins were detected but no alcohol-soluble glucosides. The sap contains succinic acid, a glucosidase, an unsaponifiable oil, a water-soluble substance melting at 191.5 °C. and having the composition C11H21O9, and an acetone-soluble substance giving lignin-like color tests. Maple flavor could not be developed in any individual constituent of the sap.


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