Use of side branch in saphenous vein interposition graft for high-flow EC/IC bypass procedures

2005 ◽  
Vol 103 (1) ◽  
pp. 186-187 ◽  
Author(s):  
Dennis J. Rivet ◽  
John E. Wanebo ◽  
Gareth A. Roberts ◽  
Ralph G. Dacey

✓ Saphenous vein (SV) interposition grafts are often used for high-flow extracranial—intracranial bypass procedures. During these procedures, it is essential to remove air and debris from the graft and to evaluate blood flow through the graft after it has been anastomosed to other cortical vessels. In this paper, the authors describe the preservation of a large side branch on the proximal end of the SV. This side branch can be used to flush out air and debris from the graft and to evaluate blood flow during revascularization.

2009 ◽  
Vol 57 (9) ◽  
pp. 889-897 ◽  
Author(s):  
Richard D. Kenagy ◽  
Seung-Kee Min ◽  
Alexander W. Clowes ◽  
John D. Sandy

High blood flow through baboon polytetrafluorethylene aorto-iliac grafts increases neointimal vascular smooth muscle cell (SMC) death, neointimal atrophy, and cleavage of versican to generate the DPEAAE neoepitope, a marker of ADAMTS-mediated proteolysis. In this study, we have determined the effect of high blood flow on transcript abundance in the neointima for ADAMTS1, −4, −5, −8, −9, −15, and −20. We found that after 24 hr of flow, the mRNA for ADAMTS4 was significantly increased, whereas that for the other family members was unchanged. Because vascular SMC death is markedly increased in the graft after 24 hr of high flow, we next examined the possibility that the ADAMTS4 induction and the cell death are causally related. The addition of Fas ligand to SMC cultures increased both ADAMTS4 mRNA and cell death ∼5-fold, consistent with the idea that ADAMTS4-dependent cleavage of versican may be partly responsible for cell death and tissue atrophy under these conditions.


1999 ◽  
Vol 42 (3) ◽  
pp. 673-679 ◽  
Author(s):  
Masahide NAKAMURA ◽  
Toshinori EBA ◽  
Margot R. ROACH ◽  
Ralph G. KRATKY ◽  
Masahiro OTOMO

Author(s):  
Luís Fernando Tirapelli ◽  
Daniela Pretti da Cunha Tirapelli ◽  
Marcelo Bellini Dalio ◽  
Alfredo José Rodrigues ◽  
Paulo Roberto Barbosa Évora

Neurosurgery ◽  
2013 ◽  
Vol 74 (1) ◽  
pp. 62-70 ◽  
Author(s):  
Ryan P. Morton ◽  
Anne E. Moore ◽  
Jason Barber ◽  
Farzana Tariq ◽  
Kevin Hare ◽  
...  

Abstract BACKGROUND: High-flow extracranial-intracranial (EC-IC) bypass is performed by using radial artery graphs (RAGs) or saphenous vein grafts (SVGs) for various pathologies such as aneurysms, ischemia, and skull-base tumors. Quantifying the acceptable amount of blood flow to maintain proper cerebral perfusion has not been well established, nor have the variables that influence flow been determined. OBJECTIVE: To identify the normative range of blood flow through extracranial-intracranial RAGs and SVGs as measured by duplex ultrasonography. Multiple variables were evaluated to better understand their influence of graft flow. METHODS: All EC-IC grafts performed at Harborview Medical Center from 2005 to 2012 were retrospectively reviewed for this cohort study. Daily extracranial graft duplex ultrasonography with flow volumes and transcranial graft Doppler were examined, as were short- and long-term outcomes. Both ischemic and hyperemic events were evaluated in further detail. RESULTS: Eighty monitorable high-flow EC-IC bypasses were performed over the 8-year period. Sixty-five bypasses were performed by using RAGs and 15 were performed with SVGs. The average flow was 133 mL/min for RAGs and 160 mL/min for SVGs (P = .25). For both RAG and SVG groups, the donor and recipient vessel selected significantly impacted flow. For the RAG group only, preoperative graft diameter, postoperative hematocrit, and postoperative date significantly influenced flow. A 1-week average of >200 mL/min was 100% sensitive to cerebral hyperemia syndrome. CONCLUSION: This study establishes the normative range of duplex ultrasonographic flow after high-flow EC-IC bypass, as well the usefulness and practicality of such monitoring as a surrogate to flow in the postoperative period.


2018 ◽  
Vol 9 (7) ◽  
pp. 871-879
Author(s):  
Rajesh Shrivastava ◽  
R. S. Chandel ◽  
Ajay Kumar ◽  
Keerty Shrivastava and Sanjeet Kumar

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