scholarly journals Screening for Oral Cavity Cancer: A 1-year Experience of a Regional Hospital in Taiwan

1970 ◽  
Vol 52 (195) ◽  
pp. 902-906
Author(s):  
Tzu-Hang Chi ◽  
Chien-Han Yuan ◽  
Rong-Feng Chen

Introduction: The purpose of this study was to analyze the risk factors affecting precancerous lesions, and cancer of oral cavity, and to assess efficacy of visual screening for oral mucosal lesions. Methods: The medical records of patients older than 30 years of age with history of habitual cigarette smoking or betel quid chewing that received screening for oral mucosal lesions between January 2012 and December 2012 were retrospectively reviewed. The patients' age, gender, risk factors, screening findings, and histopathology results of biopsy were included for further analysis. Results: A total of 1341 patients were enrolled in this study. There were 1080 males and 261 females ranging from 30 to 96 years of age, with a mean age of 53.9±13.6 years. After screening, 226 (16.9%) were found to be positive of oral lesions. Among these 226 patients, 69 (30.5%) underwent biopsy under local anesthesia, and the histopathology showed malignancy in 13 (5.8%). All of the confirmed malignant cases were squamous cell carcinoma. Among them, 12 received further staging examination and one was lost to follow-up resulting in unknown stage. The early stage oral cavity cancer (stage I and II) accounted for 84.6% (11/13).   Conclusions: The detection rate of early stage oral cavity cancer in our study was reasonable. Therefore, visual screening for oral cavity cancer is recommended for patients with habitual cigarette smoking or betel quid chewing. Keywords: betel quid chewing; cigarette smoking; oral cavity cancer; screening.  

2016 ◽  
Vol 17 (1) ◽  
pp. 46-52 ◽  
Author(s):  
Kala Chand Debnath ◽  
Md. Sahab Uddin ◽  
Srijan Goswami ◽  
Oscar Herrera-Ca ◽  
Md. Tanvir Kabir ◽  
...  

Oral Oncology ◽  
2014 ◽  
Vol 50 (8) ◽  
pp. 721-731 ◽  
Author(s):  
Chun-Ta Liao ◽  
Christopher G. Wallace ◽  
Li-Yu Lee ◽  
Chuen Hsueh ◽  
Chien-Yu Lin ◽  
...  

2006 ◽  
Vol 130 (1) ◽  
pp. 57-61 ◽  
Author(s):  
Paul Chih-Hsueh Chen ◽  
Chin-Chen Pan ◽  
Chih Kuo ◽  
Chih-Pei Lin

Abstract Context.—In contrast to previous studies about the association of oral squamous cell carcinoma with human papillomavirus (HPV) 16/18, the associations between nonmalignant oral lesions (chronic inflammation, submucous fibrosis, leukoplakia, and squamous papilloma) and HPV are much less well understood. Objective.—We conducted this study using an in situ polymerase chain reaction in situ hybridization assay, which is one of the most sensitive methods for in situ viral detection. Other known oral cancer risk factors, including betel quid chewing and cigarette smoking, were also analyzed. Design.—Oral specimens from 23 patients with submucous fibrosis, 36 patients with leukoplakia, 22 patients with squamous papilloma, and 21 patients without significant lesions were analyzed for the presence of HPV DNA. Their betel quid chewing and cigarette smoking histories were reviewed. Results.—HPV-16 and HPV-18 were frequently identified in all 3 oral lesions (61.5% and 42.1%), while HPV-6 and HPV-11 were seen only in squamous papilloma (21.1% and 5.0%). HPV-18, betel quid chewing, and smoking were significantly associated with leukoplakia and squamous papilloma, while only betel quid chewing and smoking were significantly associated with submucous fibrosis. Multivariate analysis showed that the betel quid chewing habit remained an independent factor for leukoplakia and squamous papilloma. Conclusions.—Our data indicated that betel quid chewing and smoking habits are 2 important risk factors for these nonmalignant or premalignant oral lesions, while for high-risk HPV, only HPV-18—not HPV-16—is a significant risk factor for leukoplakia and squamous papilloma.


2008 ◽  
Vol 265 (11) ◽  
pp. 1403-1407 ◽  
Author(s):  
Tin-Tin Yen ◽  
Whe-Dar Lin ◽  
Ching-Ping Wang ◽  
Chen-Chi Wang ◽  
Shih-An Liu

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e17002-e17002
Author(s):  
A. Jamshed ◽  
R. Hussain ◽  
K. Rehman ◽  
H. Iqbal ◽  
S. Hameed ◽  
...  

e17002 Background: Squamous cell carcinoma of oral cavity (SCCOC) is characterized by marked geographical differences in frequency and site distribution. Pakistan is situated within the high risk zone on the global oral cancer map. However, no reliable data exists on oral cancer in this area. Our aim was to determine clinicopathological features and patterns at presentation of primary SCCOC in a comprehensive cancer centre in Pakistan. Methods: Demographic, risk factors, pathological and AJCC staging data for SCCOC treated at Shaukat Khanum Memorial Hospital for the period November 2003-October 2008 were obtained from the head and neck unit database. Results: The database identified 666 patients with biopsy proven primary SCCOC. Mean age was 53 years (range 12 - 90 years). Male (428): Female (238) ratio was M64%:F36%. The occurrence of major risk factors for oral cancer specifically smoking, betel quid chewing, naswar (smokeless tobacco) and alcohol use in males (428) was 45% (193), 28% (118), 29% (126), 3% (13), and in females (238) was 8% (20), 29% (68), 13% (30), 0% (0), respectively. Thirty-eight percent (411/666) had no association with tobacco, betel quid or alcohol use. Subsite within oral cavity; anterior tongue 41.1% (274), buccal mucosa 26.6% (177), lower gingival and alveolus 19.5% (130), upper gingival and alveolus 4.1% (27), lips 3.6% (24), retromolar trigone 2.9% (19), hard palate 1.7% (11), and floor mouth 0.6 (4). Broder's/World Health Organization histological grade; grade I 52% (334), grade II 34% (226), grade III 7% (49), and unknown 5% (36). According to AJCC 2002 system 0.2% (1), 10.8% (72), 12.2% (81), 13.2% (88), and 63.7% (420) had stage 0, I, II, III, and IV, respectively. Conclusions: Approximately 80% of patients with primary SCCOC present with stage III or IV disease with anterior tongue as the most common subsite in our hospital. While tobacco and betel quid chewing can be attributed to development of SCCOC in a significant proportion of patients, nearly 38% are unlinked to typical risks factors suggesting other environmental and genetic agents as etiological factors in this region. No significant financial relationships to disclose.


Author(s):  
Malak Mohammed ALOsaimi ◽  
Meshael Aldarrab ◽  
Lama Aldabaan ◽  
Joud Bin Dhawi ◽  
Hanan Alali

Introduction: The use of e cigarettes is on the rise in the Middle East Countries and Saudi Arabia especially.This study aims to evaluate the oral mucosal lesions caused due to electronic cigarette smoking (ECS) use and oral health, including ‘gingival pain and/or bleeding’, ‘tongue and/or inside-cheek pain’, and ‘cracked or broken teeth’ among adolescents. Materials and Methods: A cross-sectional study conducted among 1300 participant in the kingdom of Saudi Arabia using a reliable and valid online questionnaire. The questionnaire was developed by the investigators and Google forms were used to collect the information. The questions were grouped into categories relating to socio-demographic data (age, gender), type of cigarette smoking (conventional, E-cigarette or booth), and cigarette smoking behavior (frequency). Results: It was observed from the present study that even though oral mucosal lesions were more in conventional cigarette smokers but e cigarettes were not the safe option as it has ill effects also. Females used e cigarettes more (30.7%) as compared to males (28.2%). Statistically significant results were obtained for change in color of gingival, disturbed feeling in the tongue (p<0.000). Conclusion: The usage of e cigarettes was seen more among females than males. The oral health effects and especially the change in color, dryness of the oral cavity and discoloration of the teeth were seen more with the conventional cigarettes users than the e cigarettes users. E cigarettes were also associated with ill effects of the oral cavity.


2011 ◽  
Vol 74 (12) ◽  
pp. 561-566 ◽  
Author(s):  
I-How Chang ◽  
Rong-San Jiang ◽  
Yong-Kie Wong ◽  
Shang-Heng Wu ◽  
Fun-Jou Chen ◽  
...  

2007 ◽  
Vol 117 (1) ◽  
pp. 166-171 ◽  
Author(s):  
Shih-An Liu ◽  
Yong-Kie Wong ◽  
Chiu-Kwan Poon ◽  
Chen-Chi Wang ◽  
Ching-Ping Wang ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document