scholarly journals Prevalence and Factors Associated with Microalbuminuria among Type 2 Diabetic Patients : A Hospital Based Study

2018 ◽  
Vol 56 (209) ◽  
pp. 516-521 ◽  
Author(s):  
Bikram Khadka ◽  
Mohan Lal Tiwari ◽  
Binod Timalsina ◽  
Prabodh Risal ◽  
Suprita Gupta ◽  
...  

Introduction: Microalbuminuria is the earliest clinical evidence of diabetic nephropathy. However, prevalence and associated factors with microalbuminuria among type 2 diabetic patients has been understudied area of research in Nepalese context. This study aimed to determine the prevalence and factors associated with microalbuminuria among type 2 diabetic patients. Methods: This study was a hospital-based cross-sectional study. Blood samples for serum creatinine, Hemoglobin A1C, Fasting blood sugar and urine sample for microalbumin and urine creatinine were collected and analyzed using validated and standardized tools from a total of 400 Type 2 diabetic patients in Devdaha Medical College and Teaching Hospital, Rupandehi, Nepal from August 2014 to September 2017. Microalbuminuria was defined as urinary albumin-to-creatinine ratio greater than 30 and less than300 μg /mg of creatinine Results: Of 400 type 2 diabetic patients, 186 (46.5%) had microalbuminuria. The mean values of FBS, HbA1C, serum creatinine, microalbumin, microalbumin/urine creatinine ratio were higher in microalbuminuria group. Microalbuminuria was significantly positively correlated with duration of diabetes, FBS, HbA1C, serum creatinine, microalbumin, microalbumin/ urine creatinine, systolic blood pressure and diastolic blood pressure (P< 0.01). Conclusions: Our study demonstrated that nearly half of the type 2 diabetic patients had microalbuminuria. Our results emphasize to increase to accessibility to microalbuminuria testing for all the type 2 diabetic patients and bring them under medical supervision to reduce the unwanted complications of diabetes mellitus.

Medwave ◽  
2017 ◽  
Vol 17 (09) ◽  
pp. e7097-e7097
Author(s):  
Noé Atamari-Anahui ◽  
Franklin W. Martinez-Ninanqui ◽  
Liz Paucar-Tito ◽  
Luz Morales-Concha ◽  
Alejandra Miranda-Chirau ◽  
...  

Author(s):  
Thorkild Friis ◽  
Laurids R Pedersen ◽  
Susanne Arnold-Larsen ◽  
Dorthe B Nielsen

We studied 112 type 2 diabetic patients. Fourteen patients had frank proteinuria, and 37 of the remaining 98 had microalbuminuria which was more frequent in men than in women ( P<0·02). Hypertension was found in 47 of the patients, equally distributed between sexes. Male diabetics with microalbuminuria had higher systolic blood pressure than diabetics without microalbuminuria ( P<0·02). Body mass index was higher in both sexes with hypertension compared to patients without hypertension. In the hypertensive men plasma C-peptide values were higher compared to patients without hypertension ( P<0·01) irrespective of the presence of microalbuminuria. A positive correlation between blood pressure and C-peptide was found ( P<0·01) in the men. We suggest that gender should be taken into account in the analysis and interpretation of microalbuminuria in type 2 diabetes.


2020 ◽  
Author(s):  
Tina Uprety ◽  
Saroj Kunwar ◽  
Soumya Harsha Gurung ◽  
Shraddha Thapa ◽  
Sanjita Shrestha ◽  
...  

Abstract ObjectiveMetabolic syndrome and diabetes mellitus concurrently potentiates a number of risk factors, significantly higher prevalence of cardiovascular diseases. Numerous risk factors associated with diabetes gets intensified by the presence of metabolic syndrome. Diabetes and metabolic syndrome together can increase the risk of cardiovascular disease by 2 to 4 folds. The main objective of this study was to determine the prevalence of MetS in Type 2 Diabetic patients. Components of metabolic syndrome were measured and compared to determine the prevalence. Hospital based cross-sectional study was conducted from September 2019 to December 2019 at Star hospital and Modern Technical College, Sanepa, Nepal. A total number of 353 patients with type 2 diabetes visiting Star Hospital were included in the study. ResultsAmong 353 participants, metabolic syndrome was diagnosed in 242 (68.5%) participants using NCEP-ATPIII criteria. The prevalence of MetS was 68.5% among which male were 123 (76.3%) and female were 119 (61.9%). MetS was found to be highest in age group of 50-59 years with 34.2% (83) participants. Dyslipidemia with raised TG 71.4% and reduced HDL 76% was found to be most prevalent component in our study followed by hypertension 73.1%.


Author(s):  
Santisith Khiewkhern ◽  
Witaya Yoosook ◽  
Wisit Thongkum ◽  
Chitkamon Srichompoo ◽  
Sawan Thitisutti

Introduction: Diabetic Nephropathy (DN) is one of the most serious long-term complications of patients with type 2 diabetes and the leading cause of end-stage kidney failure. Early detection and risk reduction measures can prevent DN. However, data showing the survival time and factors associated with DN development among Thai patients with type 2 diabetes is currently not available. Aim: This study aims to explore the survival time and examine the risk factors associated with the development of DN among Thai patients with type 2 diabetes. Materials and Methods: This cross-sectional retrospective study was conducted during 1st January, 2002 to 3rd December, 2017 to performed and to explore the survival time and examine the risk factors associated with the development of DN among 1,540 patients with type 2 diabetes who received treatment at the Diabetes Mellitus (DM) clinic in Mahachanachai Hospital, Yasothon Province, Thailand. Data was collected from the Hospital Experience (HOSxP) program and medical records from 2002 to 2017. Kaplan-Meier and Cox’s regressions were used for data analysis. Results: From those 15 years, out of 1,540 cases 306 eligible patients with type 2 DM were selected for survival analysis. The results showed that 274 patients met the criteria for DN (89.50%) and 32 patients (10.50%) did not meet the criteria for DN. The median of DN survival time was five years. Multivariate Cox’s regression analysis confirmed that systolic blood pressure had a statistically significant association with the development of DN among hospitalised type 2 diabetic patients. Conclusion: Duration of Diabetes and Systolic blood pressure are associated with the development of DN. The application of future prevention and control measures are highly recommended to control systolic blood pressure for DN protection.


2020 ◽  
Vol Volume 13 ◽  
pp. 2189-2198
Author(s):  
Gedion Asnake Azeze ◽  
Bulcha Guye Adema ◽  
Getachew Asmare Adella ◽  
Birhanu Wondimeneh Demissie ◽  
Mohammed Suleiman Obsa

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