scholarly journals EFFICACY OF INTERFERENTIAL THERAPY ON SELECTED CARDIOPULMONARY PARAMETERS OF ASTHMATIC PATIENTS WITH POST COVID19 EXPOSURE: STUDY PROTOCOL

2021 ◽  
Author(s):  
Eniola Awolola
Keyword(s):  
Quality Of Life ◽  
Asthma Control ◽  
Muscle Relaxation ◽  
Study Data ◽  
The Body ◽  
Smooth Muscle Relaxation ◽  
Asthmatic Patients ◽  
Asthma Patients ◽  
Interferential Therapy

Background: Interferential therapy (IFT) is the application of two medium frequency currents to the skin to stimulate and activate different systems in the body using specific frequencies and frequency ranges. IFT in the thoracic region aims to reduce myalgia in the chest and upper back, reduce muscular fatigue and induce mucus expectoration. This study is designed to test the efficacy of IFT on asthma patients recently exposed to SARS-CoV-2 virus.Methods: IFT will be administered as an intervention to 28 asthma patients with and without a history of COVID-19 exposure for 20 minutes. Six continuous outcome variables at different points will be utilized as an outcome measure. Selected Baseline Pulmonary Function Test (PFT) and Cardiopulmonary Variables (CVS) will be assessed on entry into the study, Quality of life and asthma control will be evaluated every two (2) weeks of the study. Data obtained will be analyzed using descriptive and inferential statistics of repeated ANOVA; P<0.05. Discussion: The study outcome will compare the efficacy of IFT on Bronchial Asthma patients with Post COVID-19 exposure, identify the relationship between the Intervention on Asthma patients with or without COVID-19 exposure.Contribution of Paper: Asthma control in the SARS-CoV-2 virus is still unclear, this study aims to evaluate the effect of airway smooth muscle relaxation induced by IFT on the possible long-term manifestations of SARS-CoV-2 virus on asthma control, and quality of life of asthma patients. This study will add to the existing knowledge on the management of the severe acute respiratory syndrome.

scholarly journals Comparative efficacy of interferential therapy, bronchodilators, and body positioning on asthma control and quality of life of patients with bronchial asthma: Study protocol

2021 ◽  
Author(s):  
Eniola Awolola Oladejo ◽  
Sonill Maharaj Sooknunan
Keyword(s):  
Quality Of Life ◽  
Asthma Control ◽  
Bronchial Asthma ◽  
Body Position ◽  
Study Data ◽  
The Body ◽  
University Teaching ◽  
Placebo Control ◽  
Interferential Therapy

AbstractBackgroundInterferential therapy (IFT) is the application of two medium frequency currents to the skin to stimulate and activate different systems in the body using specific frequencies and frequency ranges. IFT aims to reduce myalgia in the chest and upper back, reduce muscular fatigue and induce mucus expectoration. This study is designed to compare the efficacy of IFT on asthma control and quality of life of asthma patients pre-and post-administration of bronchodilators and determine the most influential body position in its application.MethodsForty-eight (48) patients aged 18 years and above with bronchial Asthma attending the respiratory clinic at the Lagos State University Teaching Hospital, Ikeja (LASUTH) will be assessed for the study eligibility. The study design will be a double-blinded, randomized control trial with four intervention groups and four parallel placebo control groups. IFT will be administered as an intervention to patients on short and long-acting bronchodilators in an assigned fundamental body position for 20 minutes. Six continuous outcome variables at different points will be utilized as an outcome measure. Baseline Pulmonary Function Test (PFT) will be assessed on entry into the study, Quality of life and asthma control will be evaluated every two (2) weeks of the study. Data obtained will be analyzed using descriptive and inferential statistics of repeated ANOVA; P<0.05.DiscussionThe study outcome will compare the efficacy of IFT on Bronchial Asthma, identify its effect in different body positions, and compare the relationship between its application and the bronchodilator medication frequently used by the patients.Trial Registrationhttps://pactr.samrc.ac.za/TrialDisplay.aspx?TrialID=10942:PACTR202005807526130

scholarly journals Assessment of quality of life in asthma patients in 5 to 18 years of children

2020 ◽  
Vol 7 (11) ◽  
pp. 2214
Author(s):  
Nikhil Jain ◽  
Karan Joshi
Keyword(s):  
Quality Of Life ◽  
Asthma Control ◽  
Persistent Asthma ◽  
Tertiary Hospital ◽  
P Value ◽  
Cross Sectional ◽  
Asthmatic Patients ◽  
Asthma Patients ◽  
Severity Of The Disease

Background: Asthma is a common cause of morbidity and mortality with prevalence of 300 million in world. The QOL of asthmatic patients cannot be determined only on the basis the severity of the disease, but requires a measurement of personal perception. This study was conducted with the aim to assess and compare the QOL using PedsQl scale in asthma patients between 5 to 18 years of age with different demographic and clinical variables.Methods: This was a cross-sectional observational study conducted at respiratory clinic in tertiary hospital, Rewa from October 2017 to June 2019. A total number of 150 asthmatic patients and their parents participated. Asthmatic patients (N=150) and their parents, presenting to asthma clinic of Gandhi Memorial Hospital, Rewa (after applying inclusion-exclusion criteria) were assessed for QOL using PedsQl scale 3.0. Statistical analysis was performed by SPSS version 20. Test of significance by student T-test and one way ANOVA.Results: The QOL is severely hampered by asthma with mean of 59 in intermittent asthma, 51 in mild, 44.74 in moderate and 40 in severe persistent asthma, significant p value of <0.05. Younger age, level of asthma control and severity were significantly related to QOL with p value of <0.05. Sex, socioeconomic status, were insignificantly related.Conclusions: QOL is impaired as the grading of asthma increases. Impairment of Quality of life are mostly associated with low level of asthma control, poly-therapy and frequent night attacks.

scholarly journals Correlation of illness perception, asthma control, and lung function value to the quality of life of asthma outpatients

2019 ◽  
Vol 4 (1) ◽  
pp. 43
Author(s):  
Nadia Aisah Mayzika ◽  
Asri Wido Mukti
Keyword(s):  
Quality Of Life ◽  
Lung Function ◽  
Asthma Control ◽  
Illness Perception ◽  
Life Quality ◽  
Equation Modeling ◽  
Asthmatic Patients ◽  
Asthma Patients ◽  
The Relationship

Asthma is a heterogeneous disease and chronic inflammation of the respiratory tract that has an impact on the decreased quality of life. The design of this research is non-experimental cross-sectional. The variables of this study are illness perception, control of asthma, lung function values, and life quality of asthma patients. The relationship of asthma control, illness perception, lung function value, and life quality of asthma patients can be seen with structural equation modeling using Smart-PLS software. The results are only control of asthma affects life quality, where the coefficient value is 0.511, which is positive and significant (p = 0,000). Lung function value and asthma quality indicate that lung function has a positive relationship direction seen from the coefficient value of 0.306 but not significant (p = 0.061). The correlation between illness perception and life quality of asthma was negative, where the coefficient value was - 0.142 and not significantly different (p = 0.332). This means that the direction of the relationship is reversed; it means the quality of life of asthmatic patients, which affects illness perception by 14.2%. The conclusion is that the life quality of asthmatic patients is influenced by the control of asthma and lung function. But it’s different from illness perception, where there is a negative relationship between illness perception and life quality of asthma patients. Which means illness perception affects the life quality of asthma patients.

scholarly journals Fatigue is Highly Prevalent in Patients with Asthma and Contributes to the Burden of Disease

2018 ◽  
Vol 7 (12) ◽  
pp. 471 ◽  
Author(s):  
Maarten Van Herck ◽  
Martijn Spruit ◽  
Chris Burtin ◽  
Remco Djamin ◽  
Jeanine Antons ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Asthma Control ◽  
Global Strategy ◽  
Airflow Limitation ◽  
Stepwise Multiple Regression ◽  
Life Questionnaire ◽  
Exacerbation Rate ◽  
Asthmatic Patients ◽  
Severe Fatigue

The 2018 update of the Global Strategy for Asthma Management and Prevention does not mention fatigue-related symptoms. Nevertheless, patients with asthma frequently report tiredness, lack of energy, and daytime sleepiness. Quantitative research regarding the prevalence of fatigue in asthmatic patients is lacking. This retrospective cross-sectional study of outpatients with asthma upon referral to a chest physician assessed fatigue (Checklist Individual Strength-Fatigue (CIS-Fatigue)), lung function (spirometry), asthma control (Asthma Control Questionnaire (ACQ)), dyspnea (Medical Research Council (MRC) scale), exercise capacity (six-minute walk test (6MWT)), and asthma-related Quality-of-Life (QoL), Asthma Quality of Life Questionnaire (AQLQ) during a comprehensive health-status assessment. In total, 733 asthmatic patients were eligible and analyzed (47.4 ± 16.3 years, 41.1% male). Severe fatigue (CIS-Fatigue ≥ 36 points) was detected in 62.6% of patients. Fatigue was not related to airflow limitation (FEV1, ρ = −0.083); was related moderately to ACQ (ρ = 0.455), AQLQ (ρ = −0.554), and MRC (ρ = 0.435; all p-values < 0.001); and was related weakly to 6MWT (ρ = −0.243, p < 0.001). In stepwise multiple regression analysis, 28.9% of variance in fatigue was explained by ACQ (21.0%), MRC (6.5%), and age (1.4%). As for AQLQ, 42.2% of variance was explained by fatigue (29.8%), MRC (8.6%), exacerbation rate (2.6%), and age (1.2%). Severe fatigue is highly prevalent in asthmatic patients; it is an important determinant of disease-specific QoL and a crucial yet ignored patient-related outcome in patients with asthma.

Effect of vitamin D supplementation on asthma control in patients with vitamin D deficiency: the ACVID randomised clinical trial

Thorax ◽  
2020 ◽  
pp. thoraxjnl-2019-213936
Author(s):  
Rubén Andújar-Espinosa ◽  
Lourdes Salinero-González ◽  
Fátima Illán-Gómez ◽  
Manuel Castilla-Martínez ◽  
Chunshao Hu-Yang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Asthma Control ◽  
Intervention Group ◽  
Vitamin D Supplementation ◽  
Control Group ◽  
Asthmatic Patients ◽  
Secondary Endpoints

BackgroundThe relationship between asthma and vitamin D deficiency has been known for some time. However, interventional studies conducted in this regard have shown conflicting results.ObjectiveTo evaluate the efficacy of vitamin D supplementation in asthmatic patients in improving the degree of control of asthma.MethodsRandomised, triple-blind, placebo-controlled, parallel-group study in adult asthmatic patients with serum 25-hydroxyvitamin-D3 <30 ng/mL. The intervention group received oral supplementation with 16 000 IU of calcifediol per week, and the control group had placebo added to their usual asthma treatment. The study period was 6 months. The primary endpoint was the degree of asthma control as determined by the asthma control test (ACT). Secondary endpoints included quality of life measured using the mini Asthma Quality of Life Questionnaire, the number of asthma attacks, oral corticosteroid cycles, the dose of inhaled corticosteroids, number of emergency visits, unscheduled consultations with the primary care physician and hospitalisations for asthma.ResultsOne hundred and twelve patients were randomised (mean age 55 years, with 87 (78%) being women). Of the 112 patients, 106 (95%) completed the trial. Half the patients (56) were assigned to the intervention group and the other half to the control group. A statistically significant clinical improvement was observed in the intervention group (+3.09) compared with the control group (−0.57) (difference 3.66 (95% CI 0.89 to 5.43); p<0.001) as measured using ACT scores. Among the secondary endpoints, a significant improvement in the quality of life was found in the intervention group (5.34), compared with the control group (4.64) (difference 0.7 (95% CI 0.15 to 1.25); p=0.01).ConclusionAmong adults with asthma and vitamin D deficiency, supplementation with weekly oral calcifediol compared with placebo improved asthma control over 6 months. Further research is needed to assess long-term efficacy and safety.Trial registration numberNCT02805907.

Factors affecting asthma psychomorbidity, control and illness-related quality of life: what is the interaction?

2011 ◽  
Vol 26 (S2) ◽  
pp. 1745-1745
Author(s):  
N. Pilipenko ◽  
M. Karekla
Keyword(s):  
Quality Of Life ◽  
Asthma Control ◽  
Research Literature ◽  
Smoking History ◽  
Inflammatory Disorder ◽  
Chronic Inflammatory Disorder ◽  
Asthma Patients ◽  
Related Quality ◽  
The Impact

Asthma is a chronic inflammatory disorder of the airways, ounknown etiology and growing prevalence (GINA, 2009). Appropriate asthma management can control the disorder and enable patients to enjoy a good quality of life (WHO, 2007).Yet, many asthma patients are unable to maintain asthma control (Rabe et al., 2003) for various reasons, including psychological ones (Feldman et al., 2005).This study examined the prevalence of psychomorbidity, and its interaction with asthma control difficulties and asthma-related quality of life in a sample of 200 asthma patients in Cyprus. Asthma diagnoses and severity were established by medical chart review.Psychomorbidity was evaluated using the Patient Health Questionnaire (Spitzer, 1999). Additionally, the impact of asthma-specific (e.g. asthma knowledge), health-specific (e.g. smoking history) and socio-demographic (e.g. perceived poverty) factors was examined as prior research literature suggests these may significantly impact asthma control and asthma-related quality of life.Currently, the present study is in its final stages of data collection (to conclude 2010). The results will offer valuable insights into the mechanisms and factors which affect asthma control, quality of life, and psychomorbidity. In doing so, the present study will contribute to the improved understanding of asthma patients’ experiences, essential to guide medical and psychological interventions.

scholarly journals Relation of Asthma Control with Quality of Life among a Sample of Egyptian Asthmatic School Children

2019 ◽  
Vol 7 (17) ◽  
pp. 2780-2785
Author(s):  
Hala G. Elnady ◽  
Lobna S. Sherif ◽  
Rania N. Sabry ◽  
Dina Abu Zeid ◽  
Hanan Atta ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Asthma Control ◽  
Asthma Severity ◽  
Physical Symptoms ◽  
Life Questionnaire ◽  
Asthma Control Questionnaire ◽  
Asthmatic Children ◽  
Asthmatic Patients ◽  
Egyptian Children

BACKGROUND: Asthma is considered a chronic health illness that not only resulted in physical symptoms but also emotional effects. It is; therefore, so important to assess the quality of life of asthmatic patients besides their level of disease control. AIM: To determine the correlation of asthma control with the health-related quality of life (HRQOL) of asthmatic children in Egypt. METHODS: One hundred and twenty-eight asthmatic Egyptian children were enrolled in the study. They were subjected to asthma severity grading, asthma control questionnaire (ACQ) and pediatric asthma quality of life questionnaire (PAQLQ). Studied cases were taken from 6 primary and preparatory schools, Giza governorate. RESULTS: The mean child control score was significantly higher in not well-controlled asthmatics compared to well-controlled asthmatics (p < 0.005). The not well controlled asthmatic children showed significantly lower activity limitation score, symptoms score, and overall asthmatic score compared to controlled asthmatic children (p < 0.05). The severity of asthma shows significant positive correlation with symptoms score, emotional function score and overall asthmatic score (p < 0.05). CONCLUSION: The quality of life for the asthmatic children is strongly correlated with the level of asthma control and severity.

scholarly journals Clinical, functional and inflammatory evaluation in asthmatic patients after a simple short-term educational program: a randomized trial

2021 ◽  
Author(s):  
Soraia Nogueira Felix ◽  
Rosana Camara Agondi ◽  
Marcelo Vivolo Aun ◽  
Clarice Rosa Olivo ◽  
Francine Maria de Almeida ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Asthma Control ◽  
Educational Intervention ◽  
Intervention Group ◽  
Educational Activity ◽  
Control Group ◽  
Life Questionnaire ◽  
Asthmatic Patients ◽  
Quality Life

Abstract This study aimed to evaluate the clinical evolution, functional parameters and inflammatory activity of asthma in patients who submitted to an educational intervention. 58 adult patients over 18 years of age with partly controlled and uncontrolled asthma were randomized into an intervention group (IG) (N = 32) and a control group (CG) (N = 26) and evaluated for 12 weeks. The Asthma Control Test (ACT), Asthma Control Questionnaire (ACQ), Asthma Quality Life Questionnaire (AQLQ) and Beck Depression Inventory (BDI) questionnaires were applied. Spirometry, exhaled nitric oxide (NO), exhaled breath condensate (EBC) and induced sputum (IS), measurement of the peak flow and symptoms were performed. The IG patients received an educational activity for 30 minutes applied by a nurse. Statistical analysis: analysis of variance with repeated intragroup measures. IG presented a decreased number of eosinophils in IS and IL-17A in EBC, an increase in the percentage of FEV1 after bronchodilatation and an improvement in quality of life compared to the CG. There was an improvement in depression levels and a decrease in IL-4 and IL-5 in the IS and in the EBC in the IG compared to the CG. Our results suggest that an educational intervention can bring benefits concerning the control of inflammation, lung function alterations, quality of life and levels of depression in asthmatic patients. Registration: ClinicalTrials.gov; NCT03655392.

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