Intestinal Lead and Calcium Absorption: Effect of 1, 25-Dihydroxycholecalciferol and Lead Status

1990 ◽  
Vol 194 (3) ◽  
pp. 258-264 ◽  
Author(s):  
C. S. Fullmer
1988 ◽  
Vol 48 (2) ◽  
pp. 312-315 ◽  
Author(s):  
M S Sheikh ◽  
C A Santa Ana ◽  
M J Nicar ◽  
L R Schiller ◽  
J S Fordtran

Metabolism ◽  
1976 ◽  
Vol 25 (9) ◽  
pp. 989-993 ◽  
Author(s):  
Walter J. Meyer ◽  
Ib Transbol ◽  
Frederic C. Bartter ◽  
Catherine Delea

1977 ◽  
Vol 16 (04) ◽  
pp. 163-167
Author(s):  
K. Bakos ◽  
Věra Wernischová

SummaryWhole-body counting makes an important contribution of radioisotope techniques to ȁEin vivo“ absorption studies, in comparison with other methods. In a large number of subjects, the method was tested for its usefulness in the diagnosis of calcium malabsorption. The effects of drugs, of the calcium load in the gut and of the whole-body content of calcium on the absorption process were studied in a control group.


1962 ◽  
Vol 40 (4) ◽  
pp. 481-492
Author(s):  
J. G. Devlin ◽  
D. K. O'Donovan

ABSTRACT A case is reported of intermittent hypercalcaemia, hypophosphataemia and severe skeletal rarefaction with cystic changes. An occult calcium malabsorption was found. Fat, triolein and iron absorption and radiological examinations were normal. There was gross intestinal mucosal atrophy. She was shown to be in a state of negative calcium balance and this was reversed by vitamin D. A gluten-free diet also improved calcium absorption. It is postulated that the patient had severe secondary hyperparathyroidism as the skeleton reverted to normal after six months of medical treatment.


1987 ◽  
Vol 116 (3_Suppl) ◽  
pp. S163-S164
Author(s):  
G. RÜMENAPF ◽  
E. MEYER ◽  
T. BEER ◽  
P.O. SCHWILLE
Keyword(s):  
Low Dose ◽  

2020 ◽  
Vol 20 (10) ◽  
pp. 1682-1695
Author(s):  
Foziyah Zakir ◽  
Kanchan Kohli ◽  
Farhan J. Ahmad ◽  
Zeenat Iqbal ◽  
Adil Ahmad

Osteoporosis is a progressive bone disease that remains unnoticed until a fracture occurs. It is more predominant in the older age population, particularly in females due to reduced estrogen levels and ultimately limited calcium absorption. The cost burden of treating osteoporotic fractures is too high, therefore, primary focus should be treatment at an early stage. Most of the marketed drugs are available as oral delivery dosage forms. The complications, as well as patient non-compliance, limit the use of oral therapy for prolonged drug delivery. Transdermal delivery systems seem to be a promising approach for the delivery of anti-osteoporotic active moieties. One of the confronting barriers is the passage of drugs through the SC layers followed by penetration to deeper dermal layers. The review focuses on how anti-osteoporotic drugs can be molded through different approaches so that they can be exploited for the skin to systemic delivery. Insights into the various challenges in transdermal delivery and how the novel delivery system can be used to overcome these have also been detailed.


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