An Acid Catalysed Intramolecular C–C Coupling Reaction of 8-halomethyl-16-methoxy[2.2]Metacyclophanes
2005 ◽
Vol 2005
(8)
◽
pp. 495-497
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Keyword(s):
The hydrolysis of 8-bromomethyl[2.2]metacyclophane 1a with a methoxy group at the 16-position was carried out in an 80% aqueous dioxane solution by refluxing in the presence of Nafion-H (a solid perfluorinated resin sulfonic acid) as a catalyst. The reaction yielded the corresponding 8-hydroxymethyl[2.2]metacyclophane 3 and the intramolecular C–C coupling product 2 with a spiro skeleton.
1987 ◽
pp. 513
◽
1969 ◽
Vol 0
(10)
◽
pp. 558-559
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Keyword(s):
Keyword(s):