Pancreatic metastasis of invasive ductal breast carcinoma: A potential diagnostic pitfall

The 42-year-old patient, diagnosed with Stage IIA breast cancer, completed the postoperative adjuvant chemotherapy and radiotherapy. At the 11th year of diagnosis, a 3 cm tumor was detected in the pancreas and pancreatectomy was performed. Although the diagnosis of primary pancreatic adenocarcinoma was made at first, then the pancreatic metastasis of breast cancer was discovered. Pancreatic metastasis of breast cancer is extremely rare, and a limited number of patients have been reported in the literature. Here, we report an additional case of this rare tumor and the problems correlating with its diagnosis.

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Challenges in the correct assessment of a case of aggressive thyroid carcinoma with synchronous breast cancer, case report and review of the literature: essential role of radiopharmaceuticals

Current Radiopharmaceuticals ◽

10.2174/1874471013666200928105151 ◽

2020 ◽

Vol 13 ◽

Author(s):

Andra Piciu ◽

Alexandru Mester ◽

George Rusu ◽

Doina Piciu

Keyword(s):

Breast Cancer ◽

Papillary Thyroid Carcinoma ◽

Breast Carcinoma ◽

Thyroid Carcinoma ◽

Bone Metastases ◽

Essential Role ◽

Papillary Thyroid ◽

Invasive Ductal Breast Carcinoma ◽

Ductal Breast Carcinoma

Background: Thyroid carcinoma represents a complex pathology that can still be considered a medical challenge, despite having a better prognosis and life expectancy than most other neoplasms, also the scenario of multiple malignancies involving thyroid cancer is nowadays a common reality. Materials and methods: We reviewed the literature regarding the aggressive presentation of synchronous thyroid and breast cancer. In the current paper we are reporting the case of a 59 years-old woman, diagnosed with invasive ductal breast carcinoma and papillary thyroid carcinoma, presenting a natural history of both aggressive synchronous tumors. At the moment of hospitalization, the diagnostic was breast carcinoma with multiple secondary lesions, suggestive for lung and bone metastases, and nodular goiter. Results: Searching the literature PUBMED with the terms “thyroid carcinoma and synchronous breast carcinoma we found 86 studies; introducing the term “aggressive” the result included 4 studies, among them none being relevant for aggressive and synchronous. A similar search was done in SCOPUS finding 92 documents and after introducing the term aggressive, the number of papers was 8, none being for the synchronous aggressive metastatic thyroid and breast carcinoma. The majority of imaging diagnostic tools were used in this particular medical case, in order to ensure the best potential outcome. The final diagnostic was papillary thyroid carcinoma with lung and unusual multiple bone metastases and synchronous invasive ductal breast carcinoma with subcutaneous metastases. Conclusion: The case illustrates the challenges in correct assessment of oncologic patients, despite the advances in medical imaging and technologies and underlines the essential role of nuclear medicine procedures in the diagnostic and therapy protocols.

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Isolated right adrenal metastasis from an invasive ductal breast carcinoma.

10.32512/jmr/2.2.2019/10.13 ◽

2019 ◽

pp. 10-13

Keyword(s):

Breast Cancer ◽

Breast Carcinoma ◽

Invasive Ductal Carcinoma ◽

Adrenal Glands ◽

Ductal Carcinoma ◽

Adrenal Metastasis ◽

Breast Carcinomas ◽

Invasive Ductal Breast Carcinoma ◽

Invasive Breast Carcinomas ◽

Histopathological Type

Invasive ductal carcinoma (IDC) is the most common histopathological type of breast cancer, accounting for up to 85% of all invasive breast carcinomas [1]. It spreads usually to the bone first. Solitary metastasis is commonly located in the lung, liver or brain [2]. Adrenal glands locations are extremely rare [3]. We report a case of isolated metachronous right adrenal metastasis, diagnosed four years after breast IDC management. The aim is to highlight clinical, diagnostic and therapeutic characteristics of this entity.

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Uterine Metastases in a Diagnosed Case of Invasive Ductal Breast Carcinoma: A Rare Presentation

International Journal of Medical and Pharmaceutical Case Reports ◽

10.9734/ijmpcr/2021/v14i330137 ◽

2021 ◽

pp. 29-33

Author(s):

Musa Azhar ◽

Syed Abdul Mannan Hamdani ◽

Jhanzeb Iftikhar ◽

Waqas Ahmad ◽

Sajid Mushtaq ◽

...

Keyword(s):

Breast Cancer ◽

Breast Carcinoma ◽

Endometrial Hyperplasia ◽

Ductal Carcinoma ◽

Carcinoma Of The Breast ◽

Invasive Ductal Breast Carcinoma ◽

Rare Presentation ◽

Curative Intent ◽

Initial Management ◽

High Propensity

Breast cancer is the commonest cancer among females and has a high propensity to metastasize, but gynaecological organs are rarely affected. We report a case where invasive ductal carcinoma of the breast metastasized to the uterus after initial management with curative intent. Our patient was on tamoxifen, which can cause endometrial hyperplasia and lead to a challenge in eventual diagnosis.

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Breast carcinoma en Cuirasse - case report

Anais Brasileiros de Dermatologia ◽

10.1590/abd1806-4841.20131926 ◽

2013 ◽

Vol 88 (4) ◽

pp. 608-610 ◽

Cited By ~ 4

Author(s):

Gabriela Mantovanelli de Oliveira ◽

Daniele Bueno Carvalho Zachetti ◽

Hugo Rocha Barros ◽

Adriana Tiengo ◽

Ney Romiti

Keyword(s):

Breast Cancer ◽

Breast Carcinoma ◽

Cutaneous Metastasis ◽

Contralateral Breast ◽

Skin Involvement ◽

Breast Volume ◽

Invasive Ductal Breast Carcinoma ◽

Skin Infiltration ◽

One Year ◽

The Right

Cutaneous metastasis is a phenomenon that results from a tumor spreading via lymphatic or vascular embolization, direct implant during surgery or skin involvement by contiguity. The primary malignant tumor that most commonly metastasizes to the skin in women is breast cancer, which can be manifested through papulonodular lesions, erysipeloid or sclerodermiform infiltration, en cuirasse. We report the case of a female patient, 78 years old, with papular, scaly and confluent lesions in the right breast for one year, progressing to edema and skin infiltration, reduction of breast volume and plaque en cuirasse, and similar lesions in the contralateral breast and abdomen for four months. The pathological diagnosis was invasive ductal breast carcinoma with Paget-like foci, epidermal skin metastases and lymphatic embolization.

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Anal metastasis as the sentinel and isolated presentation of invasive ductal breast carcinoma

Annals of The Royal College of Surgeons of England ◽

10.1308/rcsann.2016.0108 ◽

2016 ◽

Vol 98 (5) ◽

pp. e68-e70 ◽

Cited By ~ 1

Author(s):

C Rengifo ◽

S Titi ◽

J Walls

Keyword(s):

Breast Cancer ◽

Breast Carcinoma ◽

Cancer Metastasis ◽

Breast Cancer Metastasis ◽

Axillary Lymph Nodes ◽

Axillary Lymph ◽

Invasive Ductal Breast Carcinoma ◽

Ductal Breast Carcinoma ◽

The Uk ◽

Expanding Population

Breast cancer currently affects 1 in 8 women in the UK during their lifetime. Common sites for breast cancer metastasis include the axillary lymph nodes, bones, lung, liver, brain, soft tissue and adrenal glands. There is well documented evidence detailing breast metastasis to the gastrointestinal tract but anal metastasis is exceptionally rare. We present the case of a 78-year-old woman with an anal metastasis as the sentinel and isolated presentation of an invasive ductal breast carcinoma. As advances in the treatment of breast cancer improve, and with an ageing and expanding population, there will be an increasing number of cancer survivors, and more of these unusual presentations may be encountered in the future.

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Cognitive disfunctions in women with breast cancer treated with adjuvant chemotherapy: A preliminary report

Journal of Clinical Oncology ◽

10.1200/jco.2009.27.15_suppl.e20742 ◽

2009 ◽

Vol 27 (15_suppl) ◽

pp. e20742-e20742

Author(s):

D. Gercovich ◽

H. Hirsch ◽

P. Lopez ◽

N. Gercovich ◽

L. Vázquez ◽

...

Keyword(s):

Breast Cancer ◽

Cognitive Function ◽

Adjuvant Chemotherapy ◽

Breast Carcinoma ◽

Cognitive Skills ◽

Small Sample ◽

Anxiety And Depression ◽

Adult Women ◽

Cognitive Domains ◽

The Impact

e20742 Background: Recent studies suggest that women diagnosed with breast cancer and treated with adjuvant chemotherapy may suffer cognitive deterioration. These studies, however, present a number of limitations including a small sample of patients, retrospective evaluation of cognitive skills, lack of cognitive-function measurements previous to the chemotherapy and a lack of evaluation of psycho-pathological factors that could potentially influence on the cognitive function of the subjects. The aim of this study is to present the preliminary results of a prospective study about the impact of conventional adjuvant chemotherapy on a series of cognitive domains in adult women diagnosed with breast carcinoma, monitoring frequent psycho-pathological variables such as anxiety and depression. Methods: The present is a cohort, observational study. It includes patients with a diagnosis of stage I and II breast carcinoma, treated with standard chemotherapy and able to give their consent. The protocol has 3 stages of evaluation. First evaluation: a basal measurement between diagnosis and the first chemotherapy course. The second and third evaluations are done at 8 and 14 months respectively after the first one. Each patient has been studied using a neuro-psychological battery of 17 different tests which evaluate the following cognitive domains: global cognitive functioning, intelligence, memory, language and executive functions. The levels of anxiety and depression were studied simultaneously. Further tests will be done for related samples, so as to compare changes within a group. Results: Up to date 14, patients have completed the basal battery of tests. We expect to find differences in the cognitive functions of the patients treated with adjuvant chemotherapy. The aforementioned differences will be controlled with psycho-pathological measurements. Conclusions: The present study will allow us to evaluate in a prospective and exhaustive way cognitive deficiencies in women with breast carcinoma treated with adjuvant chemotherapy. In addition, the use of psycho-pathological instruments will allow monitoring and understanding the neuro-psychological results in a more reliable way. No significant financial relationships to disclose.

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