The relationship between latent trigger point and muscle strength in healthy subjects: A double-blind study

1. A double-blind study was undertaken to determine whether the infusion of bombesin inhibits the intake of a carbohydrate-rich meal, consumed 15 min after a 300 ml banana shake, in nine lean healthy subjects and whether the possible inhibition of food intake by bombesin is mediated by cholecystokinin. 2. The amount of food eaten during infusion of bombesin (267 ±60 g) and bombesin combined with the cholecystokinin-receptor antagonist loxiglumide (269±39g) was slightly (P = 0.09) less than during saline infusion (384 ± 40 g). In addition, preprandial feelings of hunger were significantly less during infusion of both bombesin and bombesin combined with loxiglumide. 3. In conclusion, infusion of bombesin tends to inhibit the intake of a carbohydrate-rich meal after a preload by a cholecystokinin-independent mechanism.

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The effectiveness of trigger point treatment in rotator cuff pathology: A randomized controlled double-blind study

Journal of Back and Musculoskeletal Rehabilitation ◽

10.3233/bmr-181306 ◽

2019 ◽

Vol 32 (3) ◽

pp. 519-527

Author(s):

Yildiz Analay Akbaba ◽

Ebru Kaya Mutlu ◽

Suleyman Altun ◽

Ezgi Turkmen ◽

Tansu Birinci ◽

...

Keyword(s):

Rotator Cuff ◽

Trigger Point ◽

Blind Study ◽

Double Blind Study ◽

Double Blind ◽

Randomized Controlled

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A double-blind study of prophylactic effect of misoprostol on lesions of gastric and duodenal mucosa induced by oral administration of tolmetin in healthy subjects

Digestive Diseases and Sciences ◽

10.1007/bf01309338 ◽

1986 ◽

Vol 31 (S2) ◽

pp. 131S-136S ◽

Cited By ~ 72

Author(s):

Frank L. Lanza

Keyword(s):

Oral Administration ◽

Healthy Subjects ◽

Duodenal Mucosa ◽

Blind Study ◽

Double Blind Study ◽

Prophylactic Effect ◽

Double Blind

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Effect of digoxin on global respiratory muscle strength after cholecystectomy: a double blind study

Thorax ◽

10.1136/thorax.55.6.497 ◽

2000 ◽

Vol 55 (6) ◽

pp. 497-501 ◽

Cited By ~ 4

Author(s):

N M Siafakas

Keyword(s):

Muscle Strength ◽

Respiratory Muscle ◽

Blind Study ◽

Double Blind Study ◽

Respiratory Muscle Strength ◽

Double Blind

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The relationship between gluteus medius latent trigger point and muscle strength in healthy subjects

Journal of Bodywork and Movement Therapies ◽

10.1016/j.jbmt.2021.10.001 ◽

2021 ◽

Author(s):

Fatih Bagcier ◽

Ozan Volkan Yurdakul ◽

Ahmet Üşen ◽

Merve Bozdag

Keyword(s):

Muscle Strength ◽

Healthy Subjects ◽

Trigger Point ◽

Gluteus Medius ◽

The Relationship

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Methods to Assess Breathlessness in Healthy Subjects: A Critical Evaluation and Application to Analyse the Acute Effects of Diazepam and Promethazine on Breathlessness Induced by Exercise or by Exposure to Raised Levels of Carbon Dioxide

Clinical Science ◽

10.1042/cs0610429 ◽

1981 ◽

Vol 61 (4) ◽

pp. 429-439 ◽

Cited By ~ 73

Author(s):

R. D. Stark ◽

S. A. Gambles ◽

J. A. Lewis

Keyword(s):

Carbon Dioxide ◽

Healthy Subjects ◽

Critical Evaluation ◽

Double Blind Study ◽

Double Blind ◽

Cardiorespiratory Function ◽

Graded Exercise ◽

High Level ◽

A Minor ◽

The Relationship

1. Methods were devised and evaluated for inducing breathlessness by submaximal graded exercise in healthy subjects while objective measurements of cardiorespiratory function were made. Breathlessness was assessed with serial visual analogue scales (VAS), but with various measures to enhance repeatability. 2. A high level of reproducibility was obtained in spite of the subjective nature of the assessment. Individual responses were described by the relationship between breathlessness and ventilation. The sensitivity of the method was demonstrated by the use of inspiratory resistances which disturbed this relationship and caused greater breathlessness for a given level of ventilation. 3. These methods were applied to six healthy subjects to analyse the effects of acute doses of diazepam and promethazine on breathlessness induced by graded exercise or by rebreathing carbon dioxide in a double-blind study. 4. During exercise, diazepam and promethazine did not reduce breathlessness, although there was a minor trend with promethazine. During exposure to elevated levels of carbon dioxide, diazepam and promethazine had no effect on breathlessness. Diazepam and promethazine produced similar levels of sedation, but neither drug had significant effects on the ventilatory response to carbon dioxide. These preliminary findings contrast with those reported for chronic diazepam in ‘pink puffers’. 5. Raised levels of carbon dioxide caused greater breathlessness in relation to ventilation than did exercise.

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A Double-Blind Study on Acupuncture Sensations with Japanese Style of Acupuncture: Comparison between Penetrating and Placebo Needles

Evidence-based Complementary and Alternative Medicine ◽

10.1155/2018/8128147 ◽

2018 ◽

Vol 2018 ◽

pp. 1-11

Author(s):

Masako Nishiwaki ◽

Miho Takayama ◽

Hiroyoshi Yajima ◽

Morihiro Nasu ◽

Joel Park ◽

...

Keyword(s):

General Hospital ◽

Healthy Subjects ◽

Massachusetts General Hospital ◽

Blind Study ◽

Double Blind Study ◽

Insertion Depth ◽

Double Blind ◽

Acupuncture Sensation

To investigate the acupuncture sensations elicited by the Japanese style of acupuncture, penetrating acupuncture and skin-touch placebo needles were randomly administered at various insertion depths (5 and 10 mm for the penetrating needles and 1 and 2 mm for the placebo needles) at LI4 to 50 healthy subjects. Among the 12 acupuncture sensations in the Massachusetts General Hospital Acupuncture Sensation Scale (MASS), “heaviness” was the strongest and most frequently reported sensation with the 10 mm needles, but not with the 5 mm needles. There were no significant differences in number of sensations elicited, MASS index, range of spreading, and intensity of needle pain for 5 mm penetration versus 1 mm skin press and 10 mm penetration versus 2 mm skin press. The MASS index with 2 mm skin-touch needles was significantly larger than that with 1 mm skin-touch and 5 mm penetrating needles. The factor structures in the 12 acupuncture sensations between penetrating and skin-touch needles were different. The acupuncture sensations obtained in this study under satisfactorily performed double-blind (practitioner–patient) conditions suggest that a slight difference in insertion depth and skin press causes significant differences in quantity and quality of acupuncture sensations.

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